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Top Main River Cruises & Trips in October 2022

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Take an amazing cruise to Main River in October 2022 on one of Adventure-Life's hand-selected small ships. The most popular things to do on cruises to Frankfurt, Wurzburg, Bamberg, and Wertheim during October 2022 are river cruises, biking, small ship cruises, archaeological site visits, and land & sea exploration. Our cruises in October 2022 range from $1,999 to $10,699 for a trip of 5 to 15 days. Enjoy Main River in October on one of these 7 exceptional itineraries in 2022 while sailing from port-to-port on your comfortable small ship without changing hotels or repacking your bags for the entire cruise duration.  Contact one of Adventure Life's cruise planners for help planning your dream trip to Main River in October 2022.
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Panoramic view of Budapest cityscape
$3,950
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Trans-European Cruise

Strasbourg to Budapest - 13 Day Itinerary aboard MS France
  • Visit the historical city of Mainz
  • Explore Miltenberg's architecture
  • Enjoy Passau's baroque charm
  • Discover Austrian history
Activities:
Biking, River Cruises, Urban Exploration
Activity Level:
Relaxed
Explore Central Europe from the comfort of your luxury ship during this 13-day voyage aboard the MS France. VisitWürzburg, a magic city situated on the right bank of the Main River, a city famous for its baroque palace. Enjoy aguided tour to Rothenburg, a magnificent walled town set up high on …
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Explore beautiful Amsterdam
$6,499
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Rhine, Main & Danube Discovery

Amsterdam to Vienna - 15 Day Itinerary aboard River Princess
  • Visit the pastel-hued Melk Abbey
  • Würzburg Residence & Hofburg Palace
  • Sample local specialties
  • Discover Volkach wine country
  • See Bavarian Forest National Park
Starts/ Ends in:
Amsterdam / Vienna
Activities:
Archaeological Sites, Biking, Hiking, Land & Sea, River Cruise, Urban Exploration, Village Visit
Activity Level:
Relaxed
Delight in this 15-day full spectrum of Europe’s culture, history, architecture, cuisine and numerous UNESCO World Heritage sites resting along the rivers of Rhine, Main and Danube. Discover Germany’s splendidly quaint villages, towns, prominent landmarks and the region’s best …
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$3,499
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Rhine & Moselle

Strasbourg to Frankfurt - 10 Day Itinerary aboard River Queen
  • 3 UNESCO World Heritage sites
  • Experience historic Speyer
  • Explore Cochem’s castles
  • Let Moselle and Rhine captivate you
Starts/ Ends in:
Strasbourg / Frankfurt
Activities:
Archaeological Sites, Biking, Land & Sea, Small Ship Cruise, Village Visit
Activity Level:
Relaxed
Germany’s spectacular backdrops and breathtaking natural wonders will reveal themselves as you cruise along the alluring Moselle and Rhine rivers. SeeStrasbourg, a dynamic city that has changed its nationality four times, has a lot to offer.Savor a one-of-a-kind experience in historic Speyer, …
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$4,299
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Rhine, Moselle & Blissful Baden-Baden

Baden-Baden - Frankfurt - 12 Day Itinerary aboard River Queen
  • Visit 3 UNESCO World Heritage sites
  • Cruise along Moselle & Rhine rivers
  • See Germany’s oldest town - Trier
Starts/ Ends in:
Strasbourg / Frankfurt
Activities:
Archaeological Sites, Biking, Land & Sea, Small Ship Cruise, Village Visit
Activity Level:
Relaxed
Germany’s spectacular backdrops and breathtaking natural wonders will reveal themselves as you cruise along the alluring Moselle and Rhine rivers. Discover Baden-Baden, a city so stunning that they named it twice.Visit Strasbourg, a dynamic city that has changed its nationality four times, …
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Cologne, Germany
$3,199
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Classic Germany & Amsterdam

Amsterdam-Nuremberg - 8 Day Itinerary aboard River Princess
  • Sample the region’s iconic treats
  • Wander into picturesque riverscapes
  • Pass through the Dutch countryside
  • Discover Volkach wine country
Starts/ Ends in:
Amsterdam / Nuremberg
Activities:
Archaeological Sites, Hiking, Land & Sea, River Cruise, Village Visit
Activity Level:
Relaxed
The many wonders of the Rhine and Main rivers are yours to discover on this voyage through the most charming towns of Germany.BoardRiver Princess in Amsterdam and pass through the Dutch countryside to arrive in Cologne, where a blend of medieval charm and dramatic architecture are just a sample of …
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Western Church with water canal view in Amsterdam
$1,999
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A Taste of Rhine

Northbound - 5 Day Itinerary aboard Avalon Artistry II
  • Join the Guided Canal Cruise
  • Take a Guided Walk of Cologne
  • Cruise through Rhine George
  • Visit the Mechanical Music Museum
Starts/ Ends in:
Frankfurt / Amsterdam
Activities:
River Cruise, Small Ship Cruise
Activity Level:
Relaxed
Get the perfect view of Germany’s Rhine River with a sample of its charms from Frankfurt to Amsterdam.Visit Siegfried’s Mechanical Musical Instrument Museum in Rüdesheim or enjoy your free time exploring Koblenz.Take a Guided Walk of Cologne visiting the famoustwin-steepled gothic …
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Enjoy a tranquil stroll in Amsterdam
$2,099
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A Taste of Rhine (Northbound)

5 Day Itinerary aboard Avalon Imagery II
  • Join the Guided Canal Cruise
  • Take a Guided Walk of Cologne
  • Cruise through Rhine George
  • Visit the Mechanical Music Museum
Starts/ Ends in:
Frankfurt / Amsterdam
Activities:
River Cruise, Small Ship Cruise
Activity Level:
Relaxed
Discover extraordinary destinations in Germany and Holland on this Rhine River cruise to sample local charms and traditions from Frankfurt to Amsterdam. Sail through the stunning Rhine Gorge on your way to Rüdesheim—the Rhine Valley’s wonderful wine country. Hear the sounds of …
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