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St. Louis' iconic arch at night

Mark Twain's Mississippi

St. Louis to Minneapolis - Example 9 Day Cruise aboard American Queen
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Explore the land and river that inspired legendary American author Samuel Clemens, better known by his pen name, Mark Twain. Cruise northward from St. Louis, Missouri along the mighty Mississippi River, toward the city of Minneapolis. Along the way, explore port towns such as Hannibal, Missouri, the hometown of Mark Twain; Dubuque, Iowa, one of the oldest cities in the state; La Crosse, Wisconsin, a relaxed small town with a culture influenced by its history of Irish and German immigrants; and Red Wing, Minnesota, where you can admire the work of local artisans and learn about the town's role in America's westward expansion. This 9-day journey aboard American Queen introduces you to the heart of America. 
Cruise the Mississippi River on your small ship cruiseAmerican queen2St. Louis' iconic arch at night
Highlights
  • Explore the parks and museums of St. Louis, Missouri
  • See Mark Twain's childhood home and inspiration in his hometown of Hannibal
  • Relax in the laid-back lifestyle of La Crosse and its diverse influences
  • Admire the work of local artists and craftspeople in Red Wing, Minnesota
Places Visited
Trip Type:
  • Small Ship
Activity Level: Relaxed
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Full Itinerary

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Day 1: St. Louis, Missouri

Enjoy your complimentary stay at the pre-cruise hotel. The evening is yours to become acquainted with the city. Our Hospitality Desk will be located in the hotel, and our friendly staff can assist with everything from general questions about your upcoming voyage to reserving premium experiences. Both American Queen Steamboat Company and local representatives will be readily available to provide you with dining, entertainment and sightseeing options to maximize your time here.

Day 2: Alton, Missouri | Embark

This adventurist’s oasis is always welcoming to our guests – as dewdrops of watercraft greet them from the shorelines. Founded in 1837, Alton has preserved its small-town aesthetic, but mated it with the modern industry and art that birthed its contemporary ambiance. Cafés overlook limestone bluffs draped in greenery as breezes and birds alike whistle through the trees. Enjoy both the indoor and outdoor treasures that showcase the enchantment that this river town has to offer. 

Day 3: Hannibal, Missouri

  • Ship
  • 1 Breakfast, 1 Lunch, 1 Dinner
Hannibal could be described as ordinary, but the father of American literature would beg to differ. The town, with style and dignity, comes to life in the writings of Mark Twain. People, entities and livelihoods of Hannibal’s past endure within the pages of masterpieces such as “The Adventures of Huckleberry Finn” and “Life on the Mississippi,” and the town’s preservation efforts allow our quests to step right onto the page where Twain left off. Today, the river stretches north toward country that’s almost as wild and beautiful as it must have been then, and, still enlivened by the coming and going of rivercraft, this exuberant port marks the start of adventure for all who visit. 

Day 4: River Cruising

  • Ship
  • 1 Breakfast, 1 Lunch, 1 Dinner
Watch small river towns and lush landscapes slowly become lost in the horizon as sunlight plays upon the deck. Take hold of a literary classic, curl up on a plush chair in a cozy corner and relish in the moment of tranquility. Experience the fulfillment that river cruising offers.

Day 5: Clinton, Iowa

  • Ship
  • 1 Breakfast, 1 Lunch, 1 Dinner
At the height of its economy during the late 19th century, Clinton was regarded as the lumber capital of the nation. Today, agriculture plays a big part in Clinton’s economy, which is visible in beautiful rolling fields filled in late summer with luscious, fresh harvest crops. Explore the history of this fascinating river town, and discover a lifestyle that will stand out from today’s norm. 

Day 6: Dubuque, Iowa

  • Ship
  • 1 Breakfast, 1 Lunch, 1 Dinner
Explore Dubuque, the roots from which Iowa sprouted. It’s brimming with opportunity for river travelers to experience an All-America City. Check off your outdoor bucket list in the perfect nature getaway for any adventure, and explore historic districts peppered with preserved history. From the architectural delight of Tiffany-designed windows in St. Luke’s United Methodist Church to the exhibits of the Dubuque Museum of Art, this city captures artistry. Victorian meets bohemian in this ever-growing Mississippi River gem that’s sure to leave dazzling memories. 

Day 7: La Crosse, Wisconsin

  • Ship
  • 1 Breakfast, 1 Lunch, 1 Dinner
This river town has a long-standing romance with the steamboat era, and as our paddlewheeler kisses its port, guests are welcomed by its eye-catching vistas and expansive waterfront park. Within its depths, La Crosse harbors a vibrant community; the cultural exchange among it and its six sister cities showcases a deep appreciation for enrichment through diversity. Influences from far-off destinations such as Bantry, Ireland, and Bavaria, Germany, woven into the history and charm of this scenic port, will certainly stir a traveler’s soul.

Day 8: Red Wing, Minnesota

  • Ship
  • 1 Breakfast, 1 Lunch, 1 Dinner
Red Wing was included on National Geographic Traveler’s list of the world’s most historic places. The city offers endless opportunities to travel back in time and learn about settlers and pioneers who occupied the land before today, or admire the craftsmanship and creativity of local artisans of both the present and the past.

Day 9: Red Wing, Minnesota | Disembark

  • 1 Breakfast
As the journey concludes, there are other opportunities for you to take in the town. Enjoy the city at your leisure, or consider a post-cruise premium experience with airport transfer.

Ship/Hotel

American Queen

American queen2
American Queen1
American Queen Relaxation

Dates & Prices

My Preferred Start Date

Per person starting at
$2,499
Select a Date
Category E
Surrounded by wonderful period details, accompanied by every modern convenience, these cozy havens will make your cares disappear. Ample shelving and storage spaces keep necessities out of the way yet easily accessible. Has 132 sq. ft..
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Category SI
These intimate cabins with ample storage space are slightly scaled down to accommodate the independent traveler, and feature a single bed. Has 80 sq. ft.
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Category D
An expansive bay window overlooking the scenery of America’s heartland is the main draw of this spacious category. Curl up in front of the window with a new novel, and savor a moment that belongs to only you. Has 190 sq. ft. with bay window.
American Queen
Select a Date
Category C
Open your French doors, and enjoy the fresh air. Sit on the deck outside your stateroom, and take in the gently changing views of the landscape, or indulge in a leisurely morning in bed with room service Has 140-160 sq. ft. with open veranda.
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Category B
Can you imagine opening French doors to a sweeping river vista and the sweet scent of magnolia trees? Sit on the deck outside your stateroom and greet early-morning strollers, relax in bed with your favorite book or soak in a hot bath. Has 190-205 sq. ft. with open veranda.
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Category A
With a private veranda, these staterooms are so enjoyable that you might decide to extend your journey. Relax in a cozy armchair and enjoy the view as you anticipate the activities of the day. Has 190 sq. ft. with 40-sq.-ft. private veranda.
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Category SD
Greet the day in your cozy stateroom, relaxing before breakfast, or simply enjoy a leisurely morning in bed with room service. Has 140 sq. ft.
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Category JS
Settle into your sitting area, open the French doors to the deck, and greet the day as the banks of the river majestically slip by. Some staterooms in this category offer a view of the paddlewheel, while others provide expansive views of America’s heartland. Has 210 sq. ft. with open veranda.
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Category PS
These spacious retreats offer unmatched views, each with a 6-foot-square viewing window that overlooks the paddlewheel, for a truly authentic steam boating experience. Stateroom 383: 342 sq. ft. Staterooms 385 and 386: 302 sq. ft.
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Category DS
You will feel right at home on the river in our magnificent suites. Indulge in a soothing soak in your tub, then retire to your cozy armchair or sofa, prop your feet up on the ottoman and read through the River Times – our daily program – to discover the delights that await. Has 230 sq. ft. with open veranda.
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Category LS
Our spacious, elegant suites are furnished to provide the warm ambiance of a fine Southern estate. Open your French doors and delight in sweeping river views as you sip a beverage and share conversation in your cozy sitting area. These suites are the ideal choice for family and friends vacationing together. 353-363 sq. ft. with private or open veranda
American Queen
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Category OS
Open French doors and step out onto your veranda to unwind on your amply furnished patio. Adorned with 11- foot vaulted ceilings, overhead lighting and a cozy interior lounging area with a sofa-bed and cocktail tables, these expansive suites can accommodate up to three guests, and epitomize luxurious river cruising. 348 sq. ft. with 690-sq.-ft. exclusive veranda

Notes

Inclusions
  • Pre-cruise hotel night stay in the embarkation city
  • Included Hop-on/Hop-off Shore Ex on all ports of call (except embark, disembark ports) on AQSC cruises.  Traditional shore excursion program on the VCL ships.  Premium shore excursions available at an extra charge
  • Unlimited beverages including world-class wine lists, top-shelf spirits, local craft beers and specialty coffees
  • All meals including fresh lobster and USDA Prime Beef available every night
  • 24-Hour in-room dining
  • Unlimited WiFi
  • Live, Daily Entertainment and Enrichment
 
Exclusions
  • Port fees
  • Gratuities
  • Premium and Connoisseur Beverage Packages
  • Premium Shore Excursions
  • Air

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Our guide and driver were very good with their knowledge and were very helpful with our questions. It was a very pleasant visit that would have been impossible to do on our own. Hotels and restaurants were fantastic. The special places we got to go to, like the kitchens, were great. Enjoyed the entire trip!
Meyer Smolen
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