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Top Spain Trips & Tours in September 2022

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Discover Spain in September 2022 on one of these 14 tours hand-selected by the travel experts at Adventure Life. Explore the best of Salamanca, Barcelona, Bilbao, Douro River, and Cadiz during September 2022 as you enjoy wine tasting, urban exploration, small ship cruises, archaeological site visits, and land & sea exploration. Prices for trips in September 2022 range from $2,160 to $29,499 for a vacation of 5 to 15 days. Choose any of the below 14 amazing itineraries in September 2022 and customize it to make it your own with the help of one of Adventure Life's expert Spain trip planners.
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Porto with Dom Luis Bridge
$5,199
EXPLORE

Enticing Douro

11 Day Itinerary aboard MS Amadouro
  • Tour Belem Tower
  • Explore the Castelo da Pena
  • Travel to Lamego
  • Enjoy Sandeman Winery
Starts/ Ends in:
Lisbon / Regua
Activities:
Hiking, Land & Sea, River Cruise, Wine Tasting
Activity Level:
Relaxed
Rambling vineyards and charming native farms cling to the steep sides of the Douro River Valley, creating an incomparable backdrop to one of Europe’s most unspoiled regions and to Port country — the world’s oldest demarcated wine region. Visit Porto, the beautiful “City of …
Cruise Details
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The colorful streets of Spain
$7,205
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Iberian Peninsula: Bilbao to Lisbon

8 Day Itinerary aboard Sea Cloud Spirit
  • Explore the Alto Douro wine region
  • Visit the beautiful Playa de Rodas
  • Enjoy traditional Basque cuisine
  • Discover La Coruña
Starts/ Ends in:
Bilbao / Lisbon
Activities:
Sailing Schooner, Small Ship Cruise
Activity Level:
Relaxed
Culture, history, and art come face to face with traditional Galician lifestyle on this spectacular 8-day cruise. Explore Santiago de Compostela, one of the world's most famous pilgrimage sites, the goal and climax of the Camino de Santiago, a path that has existed since the 11th century. The …
Cruise Details
0
Stop in sunny Salamanca
$8,595
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Unforgettable Douro with Lisbon

14 Day Itinerary aboard Scenic Azure
  • Visit the Maritime Museum
  • Visit Palacio Nacional
  • Relax and enjoy musical performance
  • Explore the Douro Museum in Regua
Starts/ Ends in:
Lisbon / Porto
Activities:
River Cruises, Small Ship Cruises, Wine Tasting
Activity Level:
Relaxed
Discover the beautiful Douro river valley with a relaxing adventure aboard Scenic Azure. Attend an exclusive Sundowners cocktail event on the manicured lawns of the Douro Museum, and watch as the sun sinks beneath the fruitful vines of Régua’s plentiful vineyards. Tour the Baroque-style town of …
Cruise Details
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Salamanca, Spain
$4,299
EXPLORE

Enticing Douro

8 Day Itinerary aboard MS Amadouro
  • Tour the São Bento Railway Station
  • Sample Bôlas de Lamego
  • Soak up the Douro River
  • Visit the Palacio de Mateus
Starts/ Ends in:
Porto / Douro River
Activities:
Hiking, Land & Sea Exploration, Wine Tasting
Activity Level:
Relaxed
Visit Porto, the beautiful “City of Bridges,”; and Salamanca, the “Golden City,” on this 8-day Douro River cruise on MS Amadouro. Taste wines from historic wineries and soak up the genuine beauty of one of Europe’s most unadulterated landscapes. Rambling vineyards and …
Cruise Details
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The beautiful port city of Cadiz, Spain
$2,733
EXPLORE

Enchanting Landscapes and Cultures in Spain and Portugal

Seville Roundtrip - 8 Day Itinerary aboard MS La Belle de Cadix
  • Discover Andalucia and the Algarve
  • Explore the city of Seville
  • Visit Doñana National Park
  • Enjoy Spain and Portugal journey
Starts/ Ends in:
Seville / Seville
Activities:
River Cruise, Urban Exploration, Wine Tasting
Activity Level:
Relaxed
Travel to the heart of Andalusia and the Algarve on MS La Belle de Cadix. Along the Guadalquivir, discover the town of Cordoba, which combines history and modernity. Visit Seville and its Alcázar palace, an astonishing mix of architectural styles. Then, be carried away by the sublime city of …
Cruise Details
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Sprawling vineyards of France
$6,969
EXPLORE

Colors of Provence

14 Day Itinerary aboard MS Amakristina
  • Enjoy Lyon's culinary delights
  • Visit the Beaujolais wine region
  • Join a Provencal cooking lesson
  • Admire Antoni Gaudi’s works
Starts/ Ends in:
Paris / Barcelona
Activities:
Archaeological Sites, Biking, Cooking Class, River Cruise, Urban Exploration, Wine Tasting
Activity Level:
Relaxed
Cruise through France’s legendary wine growing regions, home to such famous vintages as Beaujolais and Côte du Rhône. Enjoy wine tastings at local vintners, marvel at ancient Roman ruins, stroll through medieval villages, and shop for Provencal crafts. Visit the UNESCO World …
Cruise Details
0
Discover the history and art of Barcelona
$7,059
EXPLORE

Essence of Burgundy & Provence

14 Day Itinerary aboard MS Amacello
  • Visit Chillon Castle
  • Cooking class in Valence
  • Explore Tournus
  • Enjoy the “City of Gaudi” Barcelona
Starts/ Ends in:
Chalon Sur Saone / Barcelona
Activities:
River Cruises, Urban Exploration
Activity Level:
Relaxed
From romantic cities to foodie havens and artistic epicenters, this 14-day itinerary enlivens all your senses. Spend three nights in Geneva before going to Lyon, France’s culinary capital. Savor the beauty of legendary vineyards and imbibe in local vintages like Beaujolais and Côtes du …
Cruise Details
0
Explore the history of Sardinia
$3,695
EXPLORE

Glamorous Cote D'Azur

5 Day Itinerary aboard Sea Cloud Spirit
  • Relax on the beaches of France
  • Explore vibrant Barcelona
  • Wander beautiful Nice
  • Tour Corsica's capital, Ajaccio
Starts/ Ends in:
Barcelona / Nice
Activities:
Small Ship Cruises
Activity Level:
Relaxed
Explore some of the highlights of the western Mediterranean on this delightful 5-day cruise from Spain to France aboard Sea Cloud Spirit. Begin your trip in beautiful Barcelona, exploring the art and architecture of this vibrant city, from its lush gardens to the distinctive Gaudí buildings. …
Cruise Details
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Waterways of Libourne
$7,099
EXPLORE

Taste of Bordeaux

15 Day Itinerary aboard MS Amadolce
  • Visit the Atrium
  • Tour Arcachon
  • Explore the Castle of Roquetaillade
  • Enjoy wine tasting
Activities:
Land & Sea, Wine Tasting
Activity Level:
Relaxed
Board the Amadolce and enjoy 2 nights in Bilbao and 2 nights in San Sebastian leading up to a 7-night roundtrip Bordeaux cruise, followed by 2 nights in the Loire Valley and 1 night in Paris. On your roundtrip Bordeaux cruiseenjoy one of the world’s undisputed wine regions. Iconic …
Cruise Details
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The architectures of Lyon
$4,299
EXPLORE

Essence of Burgundy & Provence - Cruise Only

8 Day Itinerary aboard MS Amacello
  • Visit Chillon Castle
  • Cooking class in Valence
  • Explore Tournus
  • Enjoy the “City of Gaudi” Barcelona
Starts/ Ends in:
Chalon Sur Saone / Barcelona
Activities:
River Cruise, Urban Exploration
Activity Level:
Relaxed
Indulge in French flavors on a palate-pleasing 8-day river cruise that highlights the essence of France’s Burgundy and Provence. Uncover the Roman history of Chalon-sur Saône and delight in charming Tournus with its towering Romanesque abbey and historic apothecary shop. Visit French …
Cruise Details
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Visit the historic Belem tower near Lisbon
$3,895
EXPLORE

Secrets of the Douro

Porto - Porto - 8 Day Itinerary aboard Emerald Radiance
  • Visit Quinta do Tedo vineyard
  • Experience Roman times
  • Explore Douro Valley
  • Admire eclectic mix architecture
Starts/ Ends in:
Lisbon / Porto Antigo
Activities:
Archaeological Site Visits, River Cruises, Village Visits, Wine Tasting
Activity Level:
Relaxed
Start your voyage in Porto by boarding the Emerald Waterways Star-Ship. The Douro, a symbol of Portugal's origin and growth as a nation, has long served as the country's lifeblood. After leaving the pastel-colored city of Porto, travel across the enchanting countryside. The riverbanks are …
Cruise Details
0
Visit the town of Pinhao, in the heart of the beautiful Douro Valley
$2,588
EXPLORE

Portugal to Spain - Porto, the Douro Valley and Salamanca

8 Day Itinerary aboard MS Infante Don Henrique
  • Admire the city of Porto at night
  • Taste the famous Porto wine
  • Explore the old city of Salamanca
  • Tour Lamego's monumental sanctuary
Activities:
River Cruises, Wine Tasting
Activity Level:
Relaxed
Taste Europe's high culture, delicious cuisine, rich history, and stunning landscapes on this 8-day round-trip cruise along the beautiful Douro River. Cross the Iberian Peninsula aboard the MSInfante Don Henrique, a comfortable ship designed to accommodate 142 passengers. Visit a wine cellar …
Cruise Details
0
Porto Cityscape, Portugal
$5,899
EXPLORE

Douro River Valley

8 Day Itinerary aboard S.S. Sao Gabriel
  • Explore the Ribeira district
  • Visit Castelo Rodrigo
  • Enjoy private tastings of Port wine
Starts/ Ends in:
Porto / Porto
Activities:
Archaeological Sites, River Cruise, Urban Exploration, Wine Tasting
Activity Level:
Relaxed
As you follow the Douro River through Portugal and into Spain, you’ll cruise past steeply terraced hillsides, quaint villages and acres of ripe vineyards. Enjoy private tastings of port. Explore Porto’s historic Ribeira district, home to iconic rabelo boats, cutting-edge cuisine and a …
Cruise Details
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Relax on the sunny beaches of Spain
$5,999
EXPLORE

Western Mediterranean Gems I

11 Day Itinerary aboard Seabourn Sojourn
  • Explore Civitavecchia
  • Walk through the coves of Sardinia
  • Enjoy the sights of Monaco
  • See medieval to modern architecture
Starts/ Ends in:
Civitavecchia / Barcelona
Activities:
Archaeological Site Visits, Small Ship Cruises
Activity Level:
Relaxed
Start your 11-day Seabourn Sojourn Western Mediterranean voyage in Civitavecchia, where Michelangelo completed Bramante's Renaissance fortifications. Sardinia's coastline is filled with deep-cut bays, rocky outcrops, and excellent beaches for strolling and playing. An explosion of color …
Cruise Details
0
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