Have questions? We're here.

Missouri Cruises 2024

Travel made your way
Talk with an expert
Build your ideal United States trip. Call 1.406.541.2677
Start Planning My Trip
Explore the rich tapestry of Missouri's river culture and history on our 6 meticulously curated river cruises for 2024. Traverse the legendary Mississippi, where each bend in the river reveals a new chapter of American heritage—from the vibrant musical roots of St. Louis to the historic battlefields that shaped Civil War narratives. Our guests are invited to immerse themselves in an array of cultural experiences, including archaeological site visits that whisper tales from bygone eras, village visits offering a glimpse into local life, and urban exploration through cities pulsating with contemporary vigor. Over 9 to 23 days, you will have opportunities to savor regional delicacies, revel in authentic American music styles, and engage with communities preserving their unique legacies along these storied waters. With options available starting at $5,545, it is an invitation to partake in a voyage as diverse as America itself—where every traveler finds something that resonates deeply with their spirit. To weave these unforgettable encounters into your own legacy of adventure,contact one of Adventure Life's tour specialists for help planning your next seamless trip along Missouri’s majestic waterways.
Filter (6 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Level
  • Experiences
  • Activities
  • Ship
  • Destinations
    • Missouri
View the iconic arch when you visit St. Louis, gateway to the west
$12,999
EXPLORE

America’s Great River

St. Paul to New Orleans - 15 Day Itinerary aboard Viking Mississippi
  • Explore St. Louis' arts scene
  • Enjoy American music styles
  • Learn Civil War history
  • Experience New Orleans' culture
  • Visit the Quad Cities
Starts / Ends:
St. Paul / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Relaxed
Discover the history, natural beauty, and distinctive regional cultures of America's great river, the mighty Mississippi, on this 15-day cruise aboard Viking Mississippi. Set sail from St. Paul, Minnesota, and venture south toward New Orleans, Louisiana. Along the way, visit small towns and …
Cruise Details
0
Mississippi River, St. Paul Minnesota
$5,545
EXPLORE

Upper Mississippi River

St. Louis, MO to St. Paul, MN - 9 Day Itinerary aboard American Melody
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Witness wildlife and nature
  • Admire local artwork in Red Wing
Starts / Ends:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Embark on a cruise along the Upper Mississippi River, exploring St. Louis, Alton, Hannibal, Muscatine, Dubuque, Winona, and Red Wing. Visit Mark Twain's home, witness diverse landscapes, and enjoy expert-guided tours. Adapt to the river's character as you relax on lounges, decks, or …
Cruise Details
0
The upper Mississippi region
$6,999
EXPLORE

America’s Heartland

St. Louis to St. Paul - 12 Day Itinerary aboard Viking Mississippi
  • Discover history of the Mississippi
  • Explore Dubuque, Iowa
  • Experience Mississippi river towns
  • Admire local artisan work
Starts / Ends:
St. Louis / St. Paul
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Relaxed
On this enlightening journey on the Upper Mississippi, hear stories of pioneers and the Lewis and Clark Expedition; walk in the footsteps of Mark Twain; and learn about the Norwegian migration. Enjoy the view as your ship navigates through the river’s intricate lock system. Experience the …
Cruise Details
0
Visit historic Minneapolis
$15,640
EXPLORE

Complete Mississippi River

New Orleans - St. Paul - 23 Day Itinerary aboard American Melody
  • Explore Natchez's Grand Homes
  • Visit Oak Alley
  • Delve into Baton Rouge's history
  • Unravel Vicksburg's Civil War
Starts / Ends:
New Orleans / St. Paul
Activity Level:
Relaxed
Embark on a 23-day Mississippi River cruise, spanning 10 states on the American Melody. Explore the cultural tapestry of the Mighty Mississippi, touching on history, charm, and scenic landscapes. From lively New Orleans to Minneapolis, discover Baton Rouge's history, St. Francisville's …
Cruise Details
0
Visit historic Minneapolis
$15,640
EXPLORE

Complete Mississippi River

New Orleans, LA to St. Paul, M - 23 Day Itinerary aboard American Symphony
  • Explore Natchez's Grand Homes
  • Visit Oak Alley
  • Delve into Baton Rouge's history
  • Unravel Vicksburg's Civil War
Starts / Ends:
New Orleans / St. Paul
Activity Level:
Relaxed
Embark on a 23-day Mississippi River cruise, spanning 10 states on the American Symphony. Explore the cultural tapestry of the Mighty Mississippi, touching on history, charm, and scenic landscapes. From lively New Orleans to Minneapolis, discover Baton Rouge's history, St. Francisville's …
Cruise Details
0
Mississippi River, St. Paul Minnesota
$6,530
EXPLORE

Upper Mississippi River

St. Louis, MO to St. Paul, MN - 9 Day Itinerary aboard American Symphony
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Witness wildlife and nature
  • Admire local artwork in Red Wing
Starts / Ends:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Embark on a cruise along the Upper Mississippi River, exploring St. Louis, Alton, Hannibal, Muscatine, Dubuque, Winona, and Red Wing. Visit Mark Twain's home, witness diverse landscapes, and enjoy expert-guided tours. Adapt to the river's character as you relax on lounges, decks, or …
Cruise Details
0
1-6 of 6 Results

United States Travel Guide

Favorite United States All Trips

Top Missouri Travel Destinations

Missouri Trips by Departure Date

Top Experiences in Missouri

Missouri Trips by Activity

More Reasons

Why Travel With Adventure Life

All News

Recognized By