Have questions? We're here.
Romantic evening light on the Rhine

Wertheim River Cruises

Travel made your way ™
Talk with an expert
Build your ideal Main River trip. Call 1.406.541.2677
Start Planning My Trip
Talk with an expert
Explore Wertheim on a river cruise. Effortlessly float between quaint villages, scenic countryside, and history-rich cities and destinations like  without unpacking your bags. Enjoy Archaeological Site Visits, Hiking, Village Visits, Wine Tasting, and Biking on a specialty Wertheim river cruise. river cruises cost from $4,449 to $27,840 for a 8 to 24 days trip. Adventure Life's Wertheim cruise specialists can help you plan the perfect trip. Contact us to get started planning your trip now.
Filter (9 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • Wertheim
Explore historic Bamberg
from $4,449
EXPLORE

Europe's Rivers & Castles - Cruise Only

Nuremberg - Luxembourg - 8 Day Itinerary aboard AmaCerto
  • Explore Wurzburg’s Baroque splendor
  • Discover Bamberg’s architecture
  • Stroll Wertheim’s charming streets
  • Visit Rudesheim’s vineyard gondola
Starts / Ends
Nuremberg / Luxembourg
Activity Level
Variable
Set sail on an 8-day river cruise aboard the MS Amacerto, exploring Europe’s charm from the scenic Main River to the Upper Middle Rhine Valley's castles and Moselle's vineyards. Visit picturesque villages like Bernkastel, Cochem, and Rothenburg, admire the Wurzburg Residenz fresco, and savor German wines and smoked beer.
Cruise Details
0
Historic Nuremberg
from $5,299
EXPLORE

Classic Christmas Markets

Nuremberg to Frankfurt - 8 Day Itinerary aboard S.S Elisabeth
  • Start cruise in Nuremberg
  • Explore Rothenburg's market
  • Taste Frankfurt’s Christmas treats
  • Enjoy guided walking tours
Starts / Ends
Nuremberg / Frankfurt
Activity Level
Variable
During this 8-Day main river cruise aboard S.S Elisabeth, Celebrate the holidays on a festive Christmas Market from Nuremberg to Frankfurt. Discover traditional markets, sample local holiday treats, and experience celebrations on a luxurious holiday-season voyage.
Cruise Details
0
Visit old town Frankfurt
from $6,749
EXPLORE

Classic Christmas Markets

Nuremberg to Frankfurt - 8 Day Itinerary aboard S.S. Emilie
  • Explore Nuremberg Christmas Market
  • Stroll Rothenburg old town
  • Tour Würzburg Residenz Palace
  • Experience Frankfurt’s Altstadt cha
Starts / Ends
Nuremberg / Frankfurt
Activities
Village Visits, Christmas Market Visits
Activity Level
Variable
During this 8-day main river cruise aboard S.S. Emilie, experience the best of Germany’s Classic Christmas markets on traditions on this magical river cruise from Nuremberg to Frankfurt. Discover sample local holiday treats, and experience celebrations on a luxurious holiday-season voyage.
Cruise Details
0
Stroll through the romantic streets of Amsterdam
from $8,299
EXPLORE

Magnificent Europe - Cruise Only

Amsterdam - Budapest - 15 Day Itinerary aboard AmaSofia
  • Experience Amsterdam's waterways
  • Tour Cologne cathedral
  • Discover Rudesheim vineyards
  • Hike Wertheim Castle ruins
Starts / Ends
Amsterdam / Budapest
Activities
Local Market Visits, Hiking, Biking, Wine Tasting, Urban Exploration, Archaeological Site Visits
Activity Level
Variable
Join a 15-day European river cruise on the MS AmaSofia, sailing through five countries along the Danube, Main, and Rhine rivers. Experience UNESCO World Heritage Sites, regional wine tastings, and guided hiking and biking excursions in Passau and Vienna.
Cruise Details
0
Rathaus in Vienna
from $7,499
EXPLORE

Magnificent Europe - Cruise Only

15 Day Itinerary aboard AmaStella
  • Marvel Passau cathedrals
  • Wander Durnstein streets
  • Discover Vienna architecture grand
  • Explore Bratislava history
Activity Level
Variable
Embark on a 15-day cruise from Budapest to Amsterdam aboard the MS Amastella, sailing the Danube, Main, and the Rhine through five captivating countries. Explore UNESCO treasures, savor Rieslings, enjoy European cuisine, and adventure through scenic landscapes.
Cruise Details
0
Enjoy a quiet moment on the banks of the Danube
from $12,190
EXPLORE

Splendours of Europe

Budapest - Amsterdam - 15 Day Itinerary aboard Emerald Dawn
  • Explore Budapest’s grand landmarks
  • Discover Bratislava’s Old Town
  • Tour Vienna’s imperial highlights
  • Visit Melk Abbey’s ancient library
Starts / Ends
Budapest / Amsterdam
Activity Level
Variable
Embark on a 14-day river cruise on the Emerald Dawn, starting in Budapest and exploring cities like Vienna, Wurzburg, and Cologne along the Danube, Rhine, and Main rivers. Experience guided tours and unique cultural highlights, culminating in Amsterdam's vibrant atmosphere.
Cruise Details
0
Explore the inspiring Amsterdam
from $4,999
EXPLORE

Grand European Tour: Budapest to Amsterdam

Budapest to Amsterdam - 15 Day Itinerary aboard Viking
  • Discover Europe’s castles & culture
  • Visit St. Stephen’s Cathedral
  • See St. Peter’s Cathedral
  • Learn Wertheim's tradition
Starts / Ends
Budapest / Amsterdam
Activity Level
Variable
Join this 15-day Grand European Tour from Amsterdam to Budapest. Explore the beauty, nature, and architecture of Netherlands, Germany, Austria, and Hungary while sailing along the Danube, Main and Rhine Rivers.
Cruise Details
0
Explore the unique architecture of Bamberg
from $5,949
Save 50%
EXPLORE

European Jewels

Budapest - Amsterdam - 15 Day Itinerary aboard River Duchess
  • Experience Frankfurt’s
  • Explore Nuremberg
  • Enjoy Rudesheim
  • Discover Vienna
Starts / Ends
Budapest / Amsterdam
Activity Level
Variable
Sail the Danube on a 15-day river cruise from Budapest to Amsterdam aboard the River Duchess. Explore historic cities, stunning landscapes, and cultural treasures with expert-guided tours, wine tastings, and local experiences.
Cruise Details
0
Budapest, the capital city of Hungary
from $14,099
EXPLORE

Ultimate European Journey

Amsterdam - Bucharest - 24 Day Itinerary aboard River Duchess
  • Visit to the Bamberg city on foot
  • Tour the Nazi Party Rally Grounds
  • Visit the beautiful Golubac castle
  • Visit to Dynasty Palace in Belgrade
Starts / Ends
Amsterdam / Bucharest
Activities
Wildlife Viewing
Activity Level
Variable
Embark on a 24-day cruise from Amsterdam to Bucharest aboard the River Duchess. Sail through eight nations, visit five capital cities, and explore UNESCO sites like Cologne Cathedral and the Rhine Valley.
Cruise Details
0
1-9 of 9 Results
  • 1

Plan smarter. Spend better.

Talk with an expert trip planner 1.800.344.6118

Plan My Trip
Tilly Pearson employee headshot
Tilly P.
Romantic evening light on the Rhine
Main River

Chat Wertheim with a specialist

Our team is waiting and ready to talk with you about your next adventure. So go ahead and book an appointment with one of our specialized trip planners.

Let's Chat
1.800.344.6118

Where is your next adventure?

Contact Chat Call
More Reasons

Why Travel With Adventure Life

All News

Featured In

How it Works

Connect

No cost, no commitment. Talk with our experts about your dream trip.

Plan

Share your travel style—we match you with the right itinerary or create one just for you.

Book

Lock in knowing every detail is handled and you’re fully supported.

Travel

Enjoy a seamless journey—and unlock 5% off your next adventure.

Top Main River Travel Destinations

Main River Trips by Departure Date

Top Experiences in Main River

Main River Trips by Duration

Main River Trips by Activity

Tilly Pearson employee headshot
Tilly P
Plan My Trip
We love travel, talk with an expert 1.800.344.6118