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Ship in the Panama Canal

Panama Canal Cruises & Tours

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Cruise through the Panama Canal with Adventure Life. It's one of the most important waterways in the world and one of mankind's most impressive feats of engineering, cutting across the isthmus of Panama and connecting the Pacific and Atlantic Oceans - a vital pathway for international trade. Originally, it was built in the early 20th century and officially opened in 1914 for commercial trade, but more than a century later, this intricate canal of locks and levies is open to cruise vessels as well, allowing adventurous travelers to witness this man-made marvel and experience the best that Panama has to offer. We offer a number of half-day and day-long add-on itineraries and also feature several cruises aboard luxurious Panama Canal small ships. Contact us when you're ready to start planning your trip to Panama!
Panama Cruises

7 Best Panama Canal Cruises for 2025-2026

Panama Cruises
Explore beautiful Costa Rica

Panama and Costa Rica by Sea: The Natural Wonders of Central America – with Smithsonian Journeys

8 Days from $6,420
Join this 8-day cruise aboard Le Champlain to explore the natural wonders and cultural heritage of Panama and Costa Rica, including the white sands of Holandes Cayes, the iconic Panama Canal, and Panama City's historic Old Quarter.
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Secrets of Central America

11 Days from $9,230
Join this 11-day Secrets of Central America cruise and explore Panama and Costa Rica, starting at San Lorenzo’s Fort and traveling from the Atlantic to the Pacific. Visit the San Blas Islands, the Pearl Islands, Darien National Park, and cross the Panama Canal. Meet local communities, and discover the biodiversity of Rio Esquinas and Curú Nature Reserve.
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Boats Moored to the Quay at Bridgetown Harbour

Barbados to Panama

15 Days from $4,350
Starting at the Caribbean port of Bridgetown, this 15-day cruise aboard the Royal Clipper sails through the turquoise Caribbean waters en route to the Panama Canal, visiting Grenada, Bonaire, Curacao, Aruba, and Colombia along the way. Explore the tropical jungles, snorkel in vibrant reefs, immerse yourself in tribal culture, and marvel at the Panama Canal.
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Panama Canal

Costa Rica and the Panama Canal

8 Days from $7,461
Discover Costa Rica & Panama on this wonderful 8-day expedition cruise aboard the National Geographic Quest. Venture into remote wilderness and hike among monkeys, sloths, and tropical birds, explore idyllic islands, snorkel over a vibrant coral reef, and take an expedition landing craft cruise through mangroves.
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The vivid colors of the San Blas Islands

Barbados to Panama

15 Days from $4,240
Set sail on a 15-day cruise with Star Clipper from Bridgetown, Barbados, exploring the Caribbean’s rich culture and history, ending in Balboa, Panama. Visit stunning destinations like Tobago Cays, Grenada, and the San Blas Islands, and experience the Panama Canal.
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The vivid colors of the San Blas Islands

Panama to Antigua

15 Days from $4,350
Set sail on a 15-day Royal Clipper cruise from Balboa, Panama, featuring a full Panama Canal transit and visits to the San Blas Islands, Cartagena, and the Caribbean gems of Aruba, Curacao, and Bonaire. Experience lush Grenada and volcanic St. Lucia, and finish your journey in Antigua, all while enjoying elegant sailing and stunning island views.
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Sunset over Cartagena, Colombia

Panama and Colombia: Exploring the Caribbean Coast

8 Days from $6,810
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coasts of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Sail from Panama City to Cartagena, with stops in Portobelo, Guna Yala, Archipelago, and more.
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All Panama Tours

Top 4 Day Tours & Short Panama Canal Trips for 2025-2026

Trip Name From Days Next Departure Summary
Panama Canal Full Transit $323 1 May 17, 2025 This Panama City one-day tour takes you on the incredible journey from the Atlantic Ocean all the way to the Pacific Ocean, traversing two impressive locks via the manmade wonder that is the Panama Canal.
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Panama Canal Partial Transit $276 ½ Apr 30, 2025 Climb aboard and experience the "Eighth Wonder of the World" first hand as you transit through the Miraflores Locks to the Pacific Ocean.
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Explore Panama City $308 ½ Apr 30, 2025 Tour Panama City with a local guide, well versed in the history of the area. See a transit of the Panama canal and tour Casco Antiguo where the pirate Henry Morgan waged his attack in 1671.
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San Lorenzo and Agua Claras Locks $355 1 Apr 30, 2025 Visit Aguas Clara Visitor Center for stunning Gatun Lake views and marvel at the historic San Lorenzo Fort. Explore scenic landscapes, rich wildlife, and Panama Canal expansion highlights in one action-packed day.
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Panama Canal Travel Guide

Ship in the Panama Canal

Top Highlights of the Panama Canal

Explore the top highlights of the Panama Canal and discover its fascinating history and engineering marvels.
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Panama Canal Travel Guide 
The Panama Canal, one of humanity's greatest feats of engineering and tenacity, connects the Atlantic to the Pacific, creating one of the most important international maritime trade routes in the world. In addition to being an important commercial waterway, it provides an excellent way for vacationers to experience the best of all of the tropics.

Activities: 
  • Snorkeling & diving
  • Sea kayaking
  • Hiking through jungles
  • Meeting indigenous communities
  • Learing about the human history that has impacted this small Central American country
  • Exploring national parks
  • Crossing through the intricate locks of the Panama Canal!
Other destinations from the Panama Canal:
In addition to the jungles and beaches of Panama, most cruises also feature several days in Costa Rica, the Caribbean, or both!
Gatun Lock of the Panama Canal

The Panama Canal

When one thinks of Panama, the famous canal is probably the first thing that comes to mind. For travelers, visiting the Panama Canal is a highlight that should be included on any trip to this country. If your interest is peaked, here is a brief history and some interesting facts about the this engineering wonder of the world.
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Some beach time

Panama Travel Info

Panama is probably best know around the world for its canal - one of the greatest engineering marvels ever built. While this is definitely something to see while visiting the country, there is so much more to experience. Panama boasts white sand beaches along the Caribbean, beautiful mountainous landscapes, modern urban areas, and wildlife galore!
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Sloth sanctuary

Panama FAQs

Have your trip to Panama booked? Now what? From the best time to visit to what the food will be like, this FAQ gives travelers more of an idea of what to expect on a trip to Panama. We have answered some of the most common traveler questions in hopes of helping you feel better prepared for the adventure.
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Blue water and lush rain forest in Panama

Best Time to Travel to Panama

Bottom Line: The best time to visit Panama is between February and April, when there is the least amount of rain and the hottest, sunniest temperatures. Value seekers might be willing to travel during the wetter months for a better deal.
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Starfish on the beach

Top Places to Visit on a Panama Cruise

The Pearl Islands, the San Blas Islands, and Coiba National Park are some of the many incredible places that a Panama cruise has to offer. These places will show you both the exotic tropical scenery and wildlife of the country.
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Watching ships pass through the Panama Canal

Panama Canal Cruise: Large vs. Small Cruise Ships

The size of your ship matters more than you would think. With a small ship you have the advantage of accessing smaller ports, beaches, locks, and canals. Additionally, generally, small ship cruises are less expensive than large ship cruises. But larger cruises have some advantages as well. Read this article to figure out what they are!
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Panama Travel Guide

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