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Top Czech Republic Trips & Tours in April 2026

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Prague City and the Charles Bridge at Sunset
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Discover Czech Republic in April 2026 on one of these 9 tours hand-selected by the travel experts at Adventure Life. Explore the best of during April 2026 as you enjoy Biking, Hiking, Wine Tasting, Local Market Visits, and Village Visits. Prices for trips in April 2026 range from $4,399 to $30,499 for a vacation of 10 to 22 days. Choose any of the below 9 itineraries in April 2026 and customize it when you contact one of Adventure Life's expert Czech Republic trip planners.
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Gorgeous evening view of Prague
from $5,024
EXPLORE

Legendary Danube

11 Day Itinerary aboard MS Amasonata
  • Discover attractive Prague
  • Visit the famous city of Pilzen
  • Enjoy Nuremberg's countryside
  • Bike along the Danube River
Activity Level
Variable
Fall in love with the Danube on this 14-day Danube River cruise aboard the MS Amasonata. Discover some of the most important cities such as Nuremberg, Regensburg, Passau, Linz, Vienna, and Budapest, and select from a large variety of daily activities and excursions. As you cruise through Eastern Germany, don't miss the excellent Bavarian cuisine!
Cruise Details
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Budapest, the capital city of Hungary
from $4,399
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Delightful Danube & Prague

Budapest to Prague - 10 Day Itinerary aboard S.S. Beatrice
  • Explore Budapest city with a guide
  • Bike along Bavarian rivers
  • Taste Wachau Valley wines
  • Savor Viennese delicacies
Starts / Ends
Budapest / Prague
Activity Level
Variable
Sail on a 10-day cruise aboard the S.S. Beatrice along the Danube River from Budapest to Prague. Discover vibrant cities, historic castles, and cultural landmarks. Explore the architectural wonders of Budapest, Vienna, and Regensburg. Savor Viennese strudel and wine, and visit medieval castles and Jewish heritage sites.
Cruise Details
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Gorgeous evening view of Prague
from $5,024
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Romantic Danube

Prague - Budapest - 11 Day Itinerary aboard MS Amaverde
  • Discover Prague’s medieval charm
  • Taste iconic Czech craft beers
  • Explore Passau’s historic streets
  • Stroll Regensburg’s old town
Starts / Ends
Prague / Budapest
Activity Level
Variable
Embark on an 11-day river cruise with stays in Prague aboard the MS Amaverde, exploring historic cities like Prague, Vienna, and Budapest. Experience the Danube’s charm with visits to UNESCO sites and enchanting towns like Salzburg and Cesky Krumlov.
Cruise Details
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Gorgeous evening view of Prague
from $5,324
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Romantic Danube

11 Day Itinerary aboard MS Amabella
  • Explore Prague's historic treasures
  • Discover Regensburg medieval charm
  • Hike Passau's scenic hills
  • Marvel Vienna's imperial elegance
Starts / Ends
Prague / Budapest
Activity Level
Variable
Embark on an 11-day river cruise aboard the MS Amabella with Prague, exploring Vienna, Bratislava, and Budapest. Discover Salzburg, Cesky Krumlov, and iconic UNESCO sites along the Danube’s romantic shores.
Cruise Details
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Hungarian parliament, Budapest
from $5,834
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Blue Danube Discovery

13 Day Itinerary aboard MS Amasonata
  • Admire charming Budapest
  • Enjoy unique Hungarian traditions
  • Discover Vienna's Imperial Palace
  • Taste Dürnstein’s unique wine
Activity Level
Variable
Discover the Danube River on this unique 13-day exploration of Europe. Start with 2 nights in historical Budapest, followed by an unforgettable 7-night Danube River cruise to Nuremberg, concluding with 3 nights in the charming city of Prague. A flexible itinerary with plenty of daily tour options allows you to design your own trip.
Cruise Details
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Panoramic view of Budapest cityscape
from $5,734
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Melodies of the Danube

Budapest - Prague - 13 Day Itinerary aboard MS Amabella
  • Discover Budapest's iconic charm
  • Explore Bratislava's regal beauty
  • Wander Vienna's historic splendor
  • Marvel at Passau’s architecture
Starts / Ends
Budapest / Prague
Activity Level
Variable
Set sail on a 13-day cruise aboard the MS Amabella and explore Prague’s wonders. Visit Prague Castle, stroll across Charles Bridge, and discover the UNESCO-listed Old Town or hike through its historic charm.
Cruise Details
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Explore Prague's colorful streets
from $8,999
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Portraits of Eastern Europe

Prague to Bucharest - 19 Day Itinerary aboard S.S. Beatrice
  • Walk through Regensburg city
  • Visit to the Spitz’ Shipping Museum
  • Tour to the Vienna Opera House.
  • See the Artstetten Castle in a tour
Starts / Ends
Prague / Bucharest
Activities
Urban Exploration, Wildlife Viewing
Activity Level
Variable
Embark on a 19-day Portraits of Eastern Europe Cruise from Prague to Bucharest aboard S.S. Beatrice. Begin in Budapest and journey through Hungary, Croatia, Serbia, Bulgaria, and Romania. Discover historical landmarks, breathtaking landscapes, and vibrant local cultures as you explore captivating cities like Belgrade, Vukovar, and Bucharest.
Cruise Details
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Frauenkirche church in Nuremberg
from $6,814
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Europe's Rivers & Castles

Prague - Paris - 14 Day Itinerary aboard MS Amaprima
  • Explore attractive Prague
  • Admire Nuremberg's Gothic churches
  • Visit the medieval city of Wertheim
  • Sail through the Rhine River gorge
Activity Level
Variable
Embark on a 14-day cruise with 3 nights in Prague and Paris aboard the MS Amaprima. Explore castle-lined shores, storybook villages, and historic treasures while savoring Germany’s famed wines, beers, and Rüdesheim coffee.
Cruise Details
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A quiet autumn morning in Bratislava
from $9,394
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Grand Danube Cruise with Prague

22 Day Itinerary aboard MS Amabella
  • Explore Prague, timeless charm
  • Cruise Regensburg, historic gem
  • Visit Salzburg, cultural treasure
  • Discover Linz, vibrant history
Starts / Ends
Prague / Bucharest
Activities
Biking, Festival Visits, Hiking, Local Market Visits, Village Visits, Wine Tasting, Land & Sea Exploration, Archaeological Site Visits
Activity Level
Variable
Embark on a 22-day cruise aboard the MS Amabella, exploring Romania, Bulgaria, Serbia, and beyond through capitals like Bucharest and Prague. Cruise the Danube, uncover legends at sites like Bran Castle and the Rock-Hewn Churches of Ivanovo, and savor timeless traditions and wines.
Cruise Details
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