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Gorgeous evening view of Prague

Top Czech Republic Trips & Tours in September 2026

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Discover Czech Republic in September 2026 on one of these 8 tours hand-selected by the travel experts at Adventure Life. Explore the best of during September 2026 as you enjoy Village Visits, Wine Tasting, Biking, Hiking, and Festival Visits. Prices for trips in September 2026 range from $5,824 to $21,075 for a vacation of 11 to 22 days. Choose any of the below 8 itineraries in September 2026 and customize it when you contact one of Adventure Life's expert Czech Republic trip planners.
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    • Czech Republic
Historic Nuremberg
from $12,275
EXPLORE

Gems of the Danube with Prague

Prague - Budapest - 11 Day Itinerary aboard Scenic Crystal
  • Explore Prague’s Gothic center
  • Discover Terezin’s memorial
  • Travel to Regensburg’s Old Town
  • Uncover Passau’s baroque beauty
Starts / Ends
Prague / Budapest
Activity Level
Variable
Join an 11-day cruise from Prague to Budapest on the Scenic Crystal, starting with three nights in Prague to explore iconic sites like the Astronomical Clock. Visit medieval towns and enjoy cultural highlights, ending your journey in Budapest with options for Jewish heritage sites or a charming Danube town.
Cruise Details
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Enjoy a beautiful river view at sunset.
from $5,824
EXPLORE

Romantic Danube

11 Day Itinerary aboard MS Amasonata
  • Tour historical sites in Prague
  • See old-world architecture
  • Bike along the Inn River
  • Choose from optional excursions
Activity Level
Variable
Spend three nights in Prague and enjoy a fascinating cruise from Vilshofen to Budapest with stops in the charming cities of Passau, Austria, Vienna, and Hungary aboard the MS Amasonata.
Cruise Details
0
Prague City and the Charles Bridge at Sunset
from $12,275
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Gems of the Danube with Prague

Prague - Budapest - 11 Day Itinerary aboard Scenic Amber
  • Discover Prague Castle grandeur
  • Uncover Passau’s Old Town
  • Wander Linz’s vibrant streets
  • Tour Melk Abbey’s opulent halls
Starts / Ends
Prague / Budapest
Activity Level
Variable
Experience an 11-day cruise from Prague to Budapest on the Scenic Amber, exploring iconic landmarks and cultural gems. Enjoy tailored excursions, delightful wine tastings, and picturesque stops in cities like Vienna and Bratislava before concluding your journey in vibrant Budapest.
Cruise Details
0
Panoramic view of Budapest cityscape
from $6,834
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Melodies of the Danube

Budapest - Prague - 13 Day Itinerary aboard MS Amabella
  • Discover Budapest's iconic charm
  • Explore Bratislava's regal beauty
  • Wander Vienna's historic splendor
  • Marvel at Passau’s architecture
Starts / Ends
Budapest / Prague
Activity Level
Variable
Set sail on a 13-day cruise aboard the MS Amabella and explore Prague’s wonders. Visit Prague Castle, stroll across Charles Bridge, and discover the UNESCO-listed Old Town or hike through its historic charm.
Cruise Details
0
Explore castle ruins outside beautiful Bratislava
from $10,494
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Grand Danube Cruise

Prague - Bucharest - 22 Day Itinerary aboard MS Amaverde
  • Stroll Regensburg’s medieval lanes
  • Explore Passau’s Baroque beauty
  • Discover Prague’s Gothic charm
  • Taste iconic Czech craft beers
Starts / Ends
Prague / Bucharest
Activities
Biking, Festival Visits, Hiking, Local Market Visits, Village Visits, Wine Tasting, Land & Sea Exploration
Activity Level
Variable
Set sail on a 22-day cruise aboard the MS Amaverde, exploring Romania, Bulgaria, Serbia, Croatia, Hungary, Austria, Germany, and the Czech Republic along the iconic Danube River. Discover historic sites like Bran Castle and the Rock-Hewn Churches of Ivanovo while immersing yourself in the region's rich culture and traditions.
Cruise Details
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A quiet autumn morning in Bratislava
from $10,494
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Grand Danube Cruise with Prague

22 Day Itinerary aboard MS Amabella
  • Explore Prague, timeless charm
  • Cruise Regensburg, historic gem
  • Visit Salzburg, cultural treasure
  • Discover Linz, vibrant history
Starts / Ends
Prague / Bucharest
Activities
Archaeological Site Visits
Activity Level
Variable
Embark on a 22-day cruise aboard the MS Amabella, exploring Romania, Bulgaria, Serbia, and beyond through capitals like Bucharest and Prague. Cruise the Danube, uncover legends at sites like Bran Castle and the Rock-Hewn Churches of Ivanovo, and savor timeless traditions and wines.
Cruise Details
0
Gorgeous evening view of Prague
from $5,824
EXPLORE

Romantic Danube

Prague - Budapest - 11 Day Itinerary aboard MS Amaverde
  • Discover Prague’s medieval charm
  • Taste iconic Czech craft beers
  • Explore Passau’s historic streets
  • Stroll Regensburg’s old town
Starts / Ends
Prague / Budapest
Activity Level
Variable
Embark on an 11-day river cruise with stays in Prague aboard the MS Amaverde, exploring historic cities like Prague, Vienna, and Budapest. Experience the Danube’s charm with visits to UNESCO sites and enchanting towns like Salzburg and Cesky Krumlov.
Cruise Details
0
Gorgeous evening view of Prague
from $6,024
EXPLORE

Romantic Danube

11 Day Itinerary aboard MS Amabella
  • Explore Prague's historic treasures
  • Discover Regensburg medieval charm
  • Hike Passau's scenic hills
  • Marvel Vienna's imperial elegance
Starts / Ends
Prague / Budapest
Activity Level
Variable
Embark on an 11-day river cruise aboard the MS Amabella with Prague, exploring Vienna, Bratislava, and Budapest. Discover Salzburg, Cesky Krumlov, and iconic UNESCO sites along the Danube’s romantic shores.
Cruise Details
0
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Kassandra Magruder Adventure Life employee profile
Kassandra M
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