Best Mainz Rhine River Cruises, Tours & Trips for 2025-2026

At the confluence of the Rhine and Main rivers, Mainz was home to the 15th century innovator Johannes Gutenberg, whose printing press revolutionized the world. When you visit this city on your Rhine River cruise, you'll learn more about the history of the press at the Gutenberg Museum. Just a few minutes stroll from the river port, spend some time strolling the ancient medieval avenues of this well-preserved town.medieval buildings, intriguing cobbled streets, Roman ruins, Baroque churches, charming restaurants and eclectic shops. This part of the Rhine is considered by many to be one of the most scenically beautiful sections, and features the famous Rock of Lorelei and the neighboring towns of Koblenz and Worms and is a one-day cruise from Strasbourg, France. Contact our experts today to start planning your trip!

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10 Best Rhine River Cruises to Mainz for 2025-2026

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Enjoy a cozy Christmas market with loved ones

Christmas on the Romantic Rhine

4 Days from $1,188

Cruise the romantic Rhine Valley this Christmas and discover the famous Christmas market of Strasbourg, one of the biggest in Europe, aboard the MS Leonard Da Vinci.

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The Romantic Rhine Valley and the Rock of Lorelei

5 Days from $1,119

Experience the Rhine Valley on this 5-day round-trip river cruise from Strasbourg, France aboard the MS Monet. As you visit the towns of Koblenz, Mainz, Rudesheim, and Manheim, you'll visit iconic sites like Heidelberg, Stolzenfels Castle, and the quaint villages & savory wineries that characterize the Rhine Valley.

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The Magic of Christmas: Savory Delights And Holiday Traditions On A Rhine River Cruise

5 Days from $1,258

Join MS Beethoven in a memorable 5-day Christmas cruise on the Rhine River to explore the oldest, most revered Christmas markets in Europe. Explore the festive international Christmas markets in Rüdesheim, Mainz, and Gambsheim,

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1 Best Rhine River Cruise Deals for 2025-2026

Trip Name	From	Days	Summary
Vineyards of the Rhine & Moselle - Cruise Only	$3,949	8	MS Amaprima hosts this exciting 8-day cruise along the Rhine and Moselle. Explore splendid Cologne with its magnificent dome and admire the picturesque Rhine castles on your way to bustling Frankfurt and medieval Heidelberg. Continue to fascinating Koblenz and cruise the beautiful Moselle River Valley to charming Cochem and lovely Bernkastel. 0

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Mainz Travel Guide

Highlights of Mainz, Germany

Just a few minutes away from the dock you'll find a charming medieval city of great historic importance waiting to be explored. Don't miss these unique experiences:

Exploring the Gutenberg Museum - the pride and joy of Mainz is the museum dedicated to the Gutenberg press and the first printed pages of text in the form of the Gutenberg bible.
Tasting local wines with the locals in a half-timbered Altstadt tavern
St-Stephan-Kirche church would be yet another Gothic church if not for the spectacular blue stained glass windows made by Russian-Jewish artist Marc Chagall.
Museum für Antike Schifffahrt – The Museum of Ancient Seafaring contains the remains of several 5th century Roman warships found wrecked in the Rhine. Replicas were re-constructed based on these originals.

Popular Destinations in Mainz, Germany
Some of the most popular destinations frequently visited on a trip to Mainz, Germany are: