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Top Amsterdam Trips & Tours in September 2025

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Discover Amsterdam in September 2025 on one of these 33 tours hand-selected by the travel experts at Adventure Life. Explore the best of during September 2025 as you enjoy Biking, Wine Tasting, Hiking, Village Visits, and Land & Sea Exploration. Prices for trips in September 2025 range from $3,382 to $18,599 for a vacation of 8 to 15 days. Choose any of the below 33 itineraries in September 2025 and customize it when you contact one of Adventure Life's expert Amsterdam trip planners.
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    • Amsterdam
Heidelberg
from $7,399
EXPLORE

Rhine & Moselle Delights

15 Day Itinerary aboard MS Amaprima
  • Cruise tranquil Lake Lucerne
  • Explore Strasbourg on foot
  • Visit Trier, Germany’s oldest city
  • Admire Amsterdam's beauty
Activities
Land & Sea Exploration
Activity Level
Variable
This 15-day Rhine & Moselle River cruise aboard MS Amaprima takes you from Zurich to Basel to Amsterdam, passing through Germany and France along the way. Hike and bike in the lush Rhine Valley, stroll the "Crossroads of Europe" in Strasbourg, and savor the best wines and beers that have made this region famous.
Cruise Details
0
Discover charming Heidelberg
from $8,190
2for1
EXPLORE

Jewels of the Rhine

Amsterdam - Basel - 8 Day Itinerary aboard Emerald Sky
  • Discover the charming Koblenz
  • Visit a Black Forest village
  • Discover the beauty of Strasbourg
  • Tour Heidelberg Castle
Starts / Ends
Amsterdam / Basel
Activity Level
Variable
Set sail on an 8-day cruise from Amsterdam to Basel aboard the Emerald Sky, exploring Holland and Germany. Enjoy a canal tour in Amsterdam, visit iconic windmills, and experience cities like Cologne, Koblenz, Heidelberg, Strasbourg, and Freiburg.
Cruise Details
0
Strasbourg
from $4,639
CLP
EXPLORE

Captivating Rhine - Cruise Only

Amsterdam to Basel - 8 Day Itinerary aboard MS AmaSiena
  • Take an Amsterdam canal tour
  • Enjoy bike tours and wine tastings
  • Hike up the Philosopher's Path
  • Join a panoramic tour of Strasbourg
Starts / Ends
Amsterdam / Basel
Activity Level
Variable
Sail from Amsterdam to Basel on an 8-day Rhine River cruise aboard the MS Amasiena, passing vineyard-clad hills and fairytale castles. Explore charming towns, savor local flavors, and experience the beauty of Alsace, the Black Forest, and beyond.
Cruise Details
0
Visit beautiful and historic Strasbourg
from $7,119
EXPLORE

Rhine Castles & Swiss Alps

13 Day Itinerary aboard MS Amaserena
  • Discover Amsterdam’s charming canal
  • Explore Cologne’s historic treasure
  • Cruise Rhine Gorge’s castles
  • Visit Rudesheim’s scenic vineyards
Starts / Ends
Amsterdam / Basel
Activity Level
Variable
Sail aboard the MS Amaserena on a 13-day cruise through Europe, featuring Amsterdam’s canals, Germany’s Rhine Gorge castles, France’s Alsace charm, and Italy’s glamorous Lake Como. Explore five countries and iconic landmarks.
Cruise Details
0
Stroll along the canals of Dusseldorf
from $7,879
CLP
EXPLORE

Grand Rhine and Dutch Canals - Cruise Only

Amsterdam - Basel - 15 Day Itinerary aboard MS Amastella
  • Explore Amsterdam’s canals
  • Discover Hellevoetsluis history
  • Wander Ghent’s streets
  • Stroll Antwerp’s Old Town
Starts / Ends
Amsterdam / Basel
Activities
Wine Tasting, Hiking, Biking, Village Visits, Local Market Visits, Archaeological Site Visits
Activity Level
Variable
Join a 15-day river cruise on the MS Amastella, exploring the flavors and sights of the Netherlands, Belgium, Germany, France, and Switzerland. Enjoy local delicacies, historic castles, and guided insights into the rich culture along the UNESCO-listed Rhine Gorge.
Cruise Details
0
The warm glow of city lights in Brussels
from $4,639
CLP
EXPLORE

Best of Holland & Belgium - Cruise Only

Roundtrip Amsterdam - 8 Day Itinerary aboard MS Amastella
  • Explore Utrecht's medieval charm
  • Visit De Haar Castle’s grandeur
  • Discover Hellevoetsluis harbor
  • Stroll through historic Ghent
Starts / Ends
Amsterdam / Amsterdam
Activity Level
Variable
Sail on an 8-day cruise roundtrip from Amsterdam aboard the MS Amastella, exploring the Netherlands and Belgium's flavors, sights, and sounds. Savor Belgian chocolates, admire grand castles, and glide through Amsterdam's iconic canals.
Cruise Details
0
Ehrenfels Castle on Rhine River near Rudesheim
from $4,639
CLP
EXPLORE

Enchanting Rhine - Cruise Only

Basel - Amsterdam - 8 Day Itinerary aboard MS Amalucia
  • Explore Heidelberg's castle views
  • Savor Rudesheim's famed Riesling
  • Stroll Strasbourg's streets
  • Discover Breisach's scenic past
Starts / Ends
Basel / Amsterdam
Activity Level
Variable
Embark on an 8-day river cruise aboard the MS Amalucia, exploring cities where rich history meets modern progress. Journey along the scenic Rhine, passing 40 castles, timeless traditions, and inspiring towns like Heidelberg, where Mark Twain wrote A Tramp Abroad.
Cruise Details
0
Old city of Koblenz by night
from $10,590
2for1
EXPLORE

Rhine Highlights

Amsterdam - Basel - 8 Day Itinerary aboard Scenic Pearl
  • Admire Cologne's cathedral
  • Cruise Europe’s beautiful rivers
  • Discover history of Heidelberg
  • Enjoy Amsterdam’s canals
Starts / Ends
Amsterdam / Basel
Activity Level
Variable
Experience an enriching 8-day cruise from Amsterdam to Basel on the Scenic Pearl, uncovering historic cities and scenic towns along the Rhine. Enjoy Amsterdam's canals, Koblenz's culture, Cochem's vineyards, Baden-Baden's thermal spa, and Strasbourg's unique architecture.
Cruise Details
0
Rudesheim
from $4,639
CLP
EXPLORE

Enchanting Rhine - Cruise Only

Basel - Amsterdam - 8 Day Itinerary aboard MS Amaviola
  • Visit Heidelberg’s historic sites
  • Experience Dusseldorf’s culture
  • Explore Cologne’s Old Town
  • Enjoy Dutch specialties
Activity Level
Variable
Embark on an 8-day cruise from Basel to Amsterdam aboard the MS Amaviola, where vibrant cities and charming towns reveal rich histories. Sail along the Rhine's UNESCO World Heritage stretch, featuring stunning castles and delightful villages.
Cruise Details
0
View of Strasbourg city
from $4,639
CLP
EXPLORE

Enchanting Rhine - Cruise Only

8 Day Itinerary aboard MS Amastella
  • See Strasbourg's Gothic Cathedral
  • Enjoy Heidelberg's natural beauty
  • Hike through Rüdesheim
  • Admire Amsterdam's canals
Activity Level
Variable
From Basel, Switzerland to Amsterdam, the Netherlands, this classic 8-day cruise of the Rhine & Moselle Rivers aboard the MS Amastella will take you through scenic wine country, where you can visit, hike, and tour the historic towns, museums, and canals of Breisach, Strasbourg, Manheim & Heidelberg, the castles of Rüdesheim, and Koblenz & Cologne.
Cruise Details
0
Trier
from $5,539
CLP
EXPLORE

Rhine & Moselle Delights - Cruise Only

11 Day Itinerary aboard MS Amaprima
  • Explore “La Petite France”
  • Bike along the Rhine River
  • Discover Porta Nigra's secrets
  • Enjoy the fairytale town of Cochem
Starts / Ends
Basel / Amsterdam
Activity Level
Variable
Begin this exclusive 11-day cruise in Basel and conclude in charming Amsterdam. This voyage includes a large variety of activities so that you can choose how you want to explore the wondrous delights of the Rhine and Moselle River regions.
Cruise Details
0
Explore Basel
from $6,399
EXPLORE

Castles along the Rhine

Basel - Amsterdam - 8 Day Itinerary aboard S.S. Victoria
  • Tour the capital of Alsatian wines
  • Enjoy a visit the Romanesque cathed
  • Visit the Marksburg Castle
  • Walk through Strasbourg
Starts / Ends
Amsterdam / Basel
Activity Level
Variable
During this 8-day cruise from Basel to Amsterdam aboard the S.S. Victoria, cruise along the impressive Rhine River —Germany on one side, France on the other. Discover Alsace, whose dual French and German heritage has given it fabulous food and a winemaking tradition that goes back to the Romans.
Cruise Details
0
River through Koblenz Germany
from $3,382
EXPLORE

From Basel to Amsterdam: The Treasures of the Celebrated Rhine River

Basel to Amsterdam - 8 Day Itinerary aboard MS Symphonie
  • Visit Colmar and Unterlinden Museum
  • Explore Rhine Valley
  • Tour Mainz Old Town
  • Stroll Keukenhof Gardens
Starts / Ends
Basel / Amsterdam
Activities
Urban Exploration
Activity Level
Variable
Sail from Basel to Amsterdam on an 8-day cruise aboard MS Symphonie. Visit Colmar, Strasbourg, Mainz, Koblenz, Cologne, and Amsterdam. Choose between classic sightseeing and discovery excursions in each port. Tour historic cities, view scenic Rhine landscapes, and visit museums and gardens.
Cruise Details
0
Schloss Neuschwanstein overlooks the green countryside
from $6,499
EXPLORE

Enchanting Rhine

Zurich - Amsterdam - 12 Day Itinerary aboard MS Amaviola
  • Explore Cologne’s Old Town
  • Experience Dusseldorf, a city rich
  • Enjoy Dutch specialties
  • Visit Heidelberg’s historic sites
Activity Level
Variable
Embark on a 12-day cruise with stays in Zurich and Lucerne aboard the MS Amaviola, where vibrant cities and charming towns reveal rich histories. Sail along the Rhine's UNESCO World Heritage stretch, featuring stunning castles and delightful villages.
Cruise Details
0
Historic Zurich with River Limmat, Switzerland
from $6,499
EXPLORE

Enchanting Rhine

Zurich - Amsterdam - 12 Day Itinerary aboard MS Amastella
  • Wander Strasbourg’s charming street
  • Discover Basel’s historical gems
  • Stroll medieval walls in Lucerne
  • Explore Zurich’s vibrant history
Activity Level
Variable
Sail the Rhine on a 12-day cruise with stays in Zurich and Lucerne aboard the MS Amastella. Explore vibrant cities, storybook towns, and a UNESCO-listed landscape of castles, breweries, and timeless traditions.
Cruise Details
0
Ehrenfels Castle on Rhine River near Rudesheim
from $4,639
CLP
EXPLORE

Captivating Rhine - Cruise Only

Amsterdam - Basel - 8 Day Itinerary aboard MS Amaviola
  • Cruise Amsterdam’s scenic canals
  • Discover Cologne’s Gothic beauty
  • Explore Dusseldorf’s vibrant charm
  • Sail the Rhine Gorge’s epic views
Starts / Ends
Amsterdam / Basel
Activity Level
Variable
Embark on an 8-day cruise from Amsterdam to Basel aboard the MS Amaviola, where picturesque vineyards and historic castles await. Discover charming towns like Strasbourg and Colmar, from Rudesheimer coffee to German beer, while enjoying local flavors.
Cruise Details
0
Strasbourg
from $7,329
EXPLORE

Captivating Rhine

14 Day Itinerary aboard MS Amaviola
  • Join a guided bike tour
  • Visit Speyer
  • Enjoy Parc de l’Orangerie
  • Explore the Black Forest
Activity Level
Variable
From Amsterdam’s colorful canals to the majestic Swiss Alps, enjoy a 14-day exploration of the Rhine Valley, starting with two days in Amsterdam followed by 7 nights aboard the MS Amaviola, and concluding with four nights in Switzerland between Lucerne and Zurich. Sample the local brews of beer and coffee with chances to hike and bike as well!
Cruise Details
0
Explore Basel
from $6,499
EXPLORE

Enchanting Rhine

Zurich - Amsterdam - 12 Day Itinerary aboard MS Amacerto
  • Explore Zurich's vibrant history
  • Wander Strasbourg's streets
  • Visit Breisach's countryside
  • Cruise Rhine's stunning castles
Starts / Ends
Zurich / Amsterdam
Activity Level
Variable
Set sail from Zurich to Amsterdam on a 12-day Rhine cruise aboard the MS Amacerto. Discover vibrant cities, storied towns, and timeless traditions amid stunning castles and scenic riverbanks.
Cruise Details
0
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