Have questions? We're here.
Sunset over the Mekong River

Best Mekong Cruises

Travel made your way
Talk with an expert
Build your ideal Mekong River trip. Call 1.406.541.2677
Start Planning My Trip
Cruise the Mekong River into the heart of the Indochina Peninsula - starting high in the Himalayas, the Mekong River winds down through Tibet and China before defining the border of Myanmar and Laos and then flowing into Thailand, Cambodia, and Vietnam. Our Mekong cruises immerse travelers in Buddhist culture, visiting temples and most notably the expansive ruins at Angkor Wat. Trekking through villages along the Mekong River can be a humbling experience that only grows your appreciation of a simple lifestyle. You'll also stop in major cosmopolitan cities like Ho Chi Minh City in Vietnam and Cambodia's buzzing capital of Phnom Penh. Let us know when you're ready to start planning your cruise on the Mekong River!
Filter (65 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • Mekong River
Phnom Penh Royal Palace complex
from $1,355
20% Off
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard The Jahan
  • Observed locals along the river
  • See Cai Be’s rice & candy making
  • Explore the Gieng Island
  • Visit Phnom Penh cultural sites
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jahan. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.
Cruise Details
0
Phnom Penh Golden Temple
from $3,015
20% Off
EXPLORE

Mekong River - Upstream - Low water

Saigon - Siem Reap - 8 Day Itinerary aboard The Jahan
  • Visit Phnom Penh landmarks
  • Explore Kampong Laeang pottery
  • Meet Binh Thanh weavers
  • Explore Angkor Ban village
Starts / Ends
My Tho / Siem Reap
Activity Level
Variable
Journey 8 days from Saigon to Siem Reap aboard The Jahan, exploring the Mekong River’s changing landscapes and riverside life. Visit workshops in Cai Be, fruit gardens on Tan Phong Island, and communities in Cambodia that craft silver, weave silk, and make mats. Discover Phnom Penh, Angkor Ban, and the temples near Kampong Cham.
Cruise Details
0
Sunset over the Mekong River
from $4,105
EXPLORE

Classic Mekong

Upstream - 8 Day Itinerary aboard RV Bassac Pandaw
  • Explore the floating fish farms
  • Discover Ben Tre orchards
  • See Phnom Penh's National Museum
  • Tour local pottery village
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Fishing
Activity Level
Variable
Explore both Vietnam's and Cambodia's striking cultural contrast in this 8-day Upstream Classic Mekong Cruise from Saigon to Siem Reap aboard RV Bassac Pandaw. Navigate the Mekong and Tonle Sap Rivers, visit historic temples, rural villages, floating fish farms, and bustling markets.
Cruise Details
0
Everyday life in Vietnam
from $3,049
EXPLORE

Charms of the Mekong - Cruise Only

Ho Chi Minh - Siem Reap - 8 Day Itinerary aboard AmaDara
  • Explore Cai Be’s vibrant workshops
  • Discover Sa Dec history
  • Visit Phnom Penh landmarks
  • Experience Oknhatey, silk weaving
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Embark on an 8-day river cruise aboard the MS Amadara, starting in Ho Chi Minh City, a vibrant blend of history and modernity. Cruise the Mekong River, exploring villages, pagodas, and markets and experiencing local traditions, including a monk’s blessing and artisan crafts.
Cruise Details
0
The colorful Tonle Sap village
from $10,570
EXPLORE

Mekong Expedition - Ho Chi Minh to Siem Reap (Extension)

Low water - 8 Day Itinerary aboard Aqua Mekong
  • Discover My An Hung
  • Enjoy a traditional performance
  • Learn to cook Mekong dishes
  • Visit Cambodia's National Museum
  • Past by Buddhist temples
Activity Level
Variable
From Ho Chi Minh, Vietnam to Phnom Penh, Cambodia, luxurious Aqua Mekong takes you on this 8-day Mekong River cruise, visiting Buddhist temples, local villages & markets, and touring Chau Doc, Kampong Chhnang, Kampong Tralach, Koh Oknha Tey, and Sa Dec.
Cruise Details
0
Explore the floating village of Tonle Sap
from $10,570
EXPLORE

Mekong Expedition - Phnom Penh to Ho Chi Minh

8 Day Itinerary aboard Aqua Mekong
  • Walk across Kampong Prasat
  • Learn more about the local products
  • Visit the Tuol Sleng Museum
  • Discover Tan Chau
Starts / Ends
Phnom Penh / Ho Chi Minh City
Activities
Kayaking
Activity Level
Variable
Admire the diverse cultures and stunning natural beauty of Cambodia & Vietnam on this 8-day river cruise aboard Aqua Mekong. Hikes and bike rides complement cultural tours and market visits as you explore the cities & sites of Cai Be, Chau Doc, Ho Chi Minh City, Kampong Chhnang, Kampong Tralach, Koh Chen, and Phnom Penh.
Cruise Details
0
Royal Palace and Silver Pagoda
from $1,354
20% Off
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard Jayavarman
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit the Gieng Island
Starts / Ends
Phnom Penh / Ho Chi Minh City
Activities
Village Visits, Local Market Visits, Archaeological Site Visits
Activity Level
Variable
Cruise downstream on the Mekong River in majestic style aboard the Jayavarman on this 4-day journey from Phnom Penh to Saigon. Learn about the culture and heritage with visits to rural villages, historic pagodas, and colorful markets
Cruise Details
0
Vietnam's bird sanctuary
from $10,570
EXPLORE

Mekong Expedition - Ho Chi Minh to Siem Reap

High water - 8 Day Itinerary aboard Aqua Mekong
  • Experience vibrant markets
  • Enjoy touring Cambodia's capital
  • Visit Long Son Pagoda
  • Explore Prek Toal Core Bird Reserve
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Cooking Classes, Wildlife Viewing
Activity Level
Variable
Board the Aqua Mekong for an unforgettable 8-day cruise up the Mekong River from Saigon, Vietnam, to Siem Reap, Cambodia, with stops in Phnom Penh and Tonle Sap Lake, among other highlights of the Indochina peninsula. Biking, hiking, cultural immersion, market visits, and cooking classes highlight the cruise.
Cruise Details
0
Traditional mat-making
from $1,355
20% Off
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard The Jahan
  • Hear Khmer Rouge survivor story
  • Explore Gieng Island
  • Explore My An Hung Village
  • Discover water hyacinth weaving
  • Experience Tan Phong Island
Starts / Ends
Phnom Penh / Ho Chi Minh City
Activities
Biking
Activity Level
Variable
On this 4-day journey from Phnom Penh to Saigon, cruise downstream on the lower Mekong River in majestic style aboard the Jahan. See the stunning scenery and discover the culture and history of the various towns along the mighty Mekong.
Cruise Details
0
The Vinh Trang Temple in My Tho, Vietnam
from $3,675
EXPLORE

From the Angkor Temples to the Mekong Delta

Siem Reap - Ho Chi Minh - 11 Day Itinerary aboard RV Indochine
  • Visit the Banteay Srei temple
  • Explore the terrace of Elephants
  • Discover Kampong Chhnang
  • Tour Phnom Penh's National Museum
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Land & Sea Exploration
Activity Level
Variable
Experience an 11-day cruise on the RV Indochine from Siem Reap to Ho Chi Minh City, navigating over 2,700 miles of the Mekong River. Explore cultural landmarks like Angkor and Phnom Penh, all while enjoying colonial-inspired comfort aboard your vessel.
Cruise Details
0
Angkor Wat
from $3,645
EXPLORE

From the Temples of Angkor to the Mekong Delta

11 Day Itinerary aboard RV Indochine II
  • Observe the jewel of Khmer art
  • Stop at the “the port of pottery”
  • Observe local craftsmen at work
  • Travel to a beekeeping farm
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Urban Exploration
Activity Level
Variable
On this 11-day cruise of Cambodia & Vietnam aboard the RV Indochine II explore the fascinating Mekong river, its people, culture and history. Explore the waterways of Southeast Asia from the comfort of your floating hotel, making stops to visit Angkor, Tonle Sap, Kampong Tralach, Phnom Penh, My Tho, Ho-Chi- Minh City, and more.
Cruise Details
0
Woman on a boat in Vietnam
from $2,389
EXPLORE

From the Mekong Delta to Siem Reap

Ho Chi Minh City - Siem Reap - 9 Day Itinerary aboard RV Indochine II
  • Join a tour of Ho Ci Minh City
  • Observe Chau Doc´s vibrant market
  • Experience a trip in a “tuk tuk”
  • See Kampong Chhnang´s fish farms
Activity Level
Variable
Discover the culture and history of Vietnam & Cambodia on this 9-day cruise from Ho Chi Minh City to Siem Reap aboard the RV Indochine II, departing from Vietnam's Ho Chi Minh City towards Cambodia's Siem Reap, with stops in My Tho & Phnom Penh along the way.
Cruise Details
0
1-12 of 65 Results

We do the homework for you.

Talk with an expert trip planner 1.800.344.6118

Plan My Trip
Jason Maynard employee profile
Jason M.
Aqua Mekong sailing up the Mekong River
Mekong River

Chat Mekong River with a specialist

Our team is waiting and ready to talk with you about your next adventure. So go ahead and book an appointment with one of our specialized trip planners.

Let's Chat
1.800.344.6118

Where is your next adventure?

Contact Chat Call
More Reasons

Why Travel With Adventure Life

All News

Featured In

How it Works

Connect

No cost, no commitment. Talk with our experts about your dream trip.

Plan

Share your travel style—we match you with the right itinerary or create one just for you.

Book

Lock in knowing every detail is handled and you’re fully supported.

Travel

Enjoy a seamless journey—and unlock 5% off your next adventure.

Top Mekong River Travel Destinations

Mekong River Trips by Departure Date

Top Experiences in Mekong River

Mekong River Trips by Duration

Mekong River Trips by Activity