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Top Mekong River Trips & Tours in December 2026

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The Vinh Trang Temple in My Tho
from $5,519
EXPLORE

From the Mekong Delta to the Temples of Angkor & Hanoi and Halong Bay

Hanoi to Angkor Temples - 14 Day Itinerary aboard RV Indochine
  • Experience Hanoi city tour
  • Cruise along Halong Bay's islands
  • Explore Ho Chi Minh landmarks
  • Explore My Tho bee farm
Starts / Ends
Hanoi / Siem Reap
Activities
Local Market Visits, Urban Exploration, Land & Sea Exploration
Activity Level
Variable
Discover Vietnam and Cambodia on a 14-day cruise from Hanoi to Siem Reap aboard RV Indochine. Cruise Halong Bay, explore Ho Chi Minh City, visit Phnom Penh, and marvel at Angkor temples. Enjoy guided tours, local markets, floating villages, and authentic cuisine with unique cultural experiences along the Mekong River.
Cruise Details
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Cycling along the bridge
from $1,338
EXPLORE

Cycling the Mekong Delta

Vietnam Small Group Tour - 7 Day Itinerary
  • Explore Ho Chi Minh City
  • See the floating market in Cai Be
  • Visit the Khmer templ in Tra Vinh
  • Explore Can Tho's charming villages
  • See the rice paddies in Long Xuyen
  • Discover Chau Doc' diverse culture
Starts / Ends
Ho Chi Minh City / Ho Chi Minh City
Activities
Biking, Homestays
Activity Level
Moderate
Cycle through the Mekong Delta on this 7-day tour from Ho Chi Minh City. Explore vibrant villages, floating markets, and authentic river life on a route that blends active cycling with local culture. Perfect for travelers seeking an extended Mekong River tour, this tour offers a deep dive into the region's scenery and traditions.
Tour Details
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Boy on wooden fishing boat
from $2,452
EXPLORE

Mekong River - Downstream - Low water

Siem Reap to Phnom Penh - 5 Day Itinerary aboard Jayavarman
  • Explore the mighty Mekong River
  • Discover pre-Angkorian temples
  • Explore Tonle's riverine
  • Learn about Phnom Penh
Starts / Ends
Siem Reap / Phnom Penh
Activity Level
Variable
Embark on a 5-day cruise along the Mekong River from Siem Reap to Phnom Penh with the Jayavarman, and cruise the expansive Mekong Delta to discover the pre-Angkorian temples and culture of Cambodia.
Cruise Details
0
Royal Palace and Silver Pagoda
from $11,350
Save $150
EXPLORE

Wonders of Vietnam, Cambodia and the Mekong

Ho Chi Minh City - Siem Reap - 13 Day Itinerary aboard Emerald Harmony
  • Explore Ho Chi Minh City’s streets
  • Venture Cu Chi’s legendary tunnel
  • Witness river life along Ben Tre
  • Stroll Sa Dec’s colorful markets
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Join a 13-day cruise through Vietnam and Cambodia aboard the Emerald Harmony, starting in Ho Chi Minh City and exploring the Mekong Delta’s villages. Conclude your adventure in Siem Reap, visiting the remarkable Angkor Wat temple complex.
Cruise Details
0
Aerial view of Angkor Wat
from $7,250
Up to 30%
EXPLORE

Mekong Explorer - Phnom Penh to Siem Reap (Extension)

5 Day Itinerary aboard Aqua Mekong
  • Watch artisans produce silverware
  • Disembark along the Tonle Sap
  • Admire Khmer artisans
Activity Level
Variable
Interact with the locals and visit colorful marketplaces and cultural attractions along the shorelines while on a tour of this beautiful region. Take a five-day cruise down the Mekong River aboard the Aqua Mekong.
Cruise Details
0
Sunset over the Mekong River
from $2,112
EXPLORE

Saigon and Phnom Penh Short Cruise

Upstream - 4 Day Itinerary aboard RV Bassac Pandaw
  • Explore floating markets
  • Cruise through Mekong Delta
  • Cambodia and Vietnam's culture
Starts / Ends
Liberty Central Saigon Riverside Hotel / Phnom Penh
Activity Level
Variable
Explore the wonders of Vietnam and Cambodia on this 4-day Saigon and Phnom Penh Short Cruise on the RV Bassac Pandaw. Immerse yourself into the contrasting culture of Vietnam Delta and Cambodia.
Cruise Details
0
Angkor Wat
from $11,350
Save $150
EXPLORE

Wonders of Cambodia, Vietnam and the Mekong

Siem Reap - Ho Chi Minh - 15 Day Itinerary aboard Emerald Harmony
  • Explore Angkor Thom’s royal city
  • Witness sunrise over Angkor Wat
  • Visit Angkor Ban’s resilient homes
  • Learn Cambodia’s history
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Set sail on a 15-day cruise from Siem Reap to Ho Chi Minh City aboard the Emerald Harmony, exploring Angkor Wat, Phnom Penh, and a Cao Dai temple in Vietnam. Experience local culture, crafts, and a two-night hotel stay in the vibrant Ho Chi Minh City.
Cruise Details
0
Khone Pha Pheng waterfall, a famous waterfall in Southern of Laos
from $1,287
EXPLORE

Southern Laos

Lao's Mekong River - 5 Day Itinerary
  • Explore Wat Phou Ancient Ruins
  • Cruise Mekong River Scenic Islands
  • View Khone Phapheng Massive Falls
  • Cycle Don Khone Peaceful Trails
  • Visit Liphi Cascading Waterfalls
Starts / Ends
Pakse / Pakse
Activity Level
Relaxed
Discover the hidden gems of Southern Laos on this immersive 5-day private adventure. You explore the ancient UNESCO ruins of Wat Phou, cruise the Mekong to the peaceful 4000 Islands, and experience local life with a fishing trip and island BBQ. The trip concludes with the stunning waterfalls and tribal villages of the cool Bolaven Plateau.
Tour Details
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The beautiful Vinh Trang temple near My Tho
from $4,091
Save 20%
EXPLORE

Mekong River - Upstream - Low water

Saigon - Siem Reap - 8 Day Itinerary aboard Jayavarman
  • Aboard a luxury riverboat in Mekong
  • Visit Cai Be workshops
  • Explore Tan Phong Island
  • Cruise the Tonle River
  • Meet monks in Angkor Ban
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Village Visits, Archaeological Site Visits, Cooking Classes
Activity Level
Variable
Sail the Mekong River aboard the Jayavarman on an 8-day cruise from Saigon to Siem Reap. Discover local life along the river, from Vietnam’s craft villages and island communities to Cambodia’s temples, silk weaving villages, and cultural traditions.
Cruise Details
0
Statues and intricate relief carvings inside Angkor Wat
from $12,350
Save $150
EXPLORE

Wonders of Vietnam, Cambodia and the Mekong

Ho Chi Minh - Siem Reap - 15 Day Itinerary aboard Emerald Harmony
  • Explore Cu Chi Tunnels
  • Tour Sa Dec’s markets
  • Visit My An Hung village
  • Discover Gieng Island industries
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Wildlife Viewing
Activity Level
Variable
Set sail on a 15-day cruise aboard Emerald Harmony, starting in Ho Chi Minh City and journeying through the Mekong River to discover villages like My An Hung and iconic sites such as the Cao Dai Temple. Conclude your adventure in Siem Reap, exploring the rich cultural heritage of Cambodia, including the famous Angkor Wat.
Cruise Details
0
Explore the floating village of Tonle Sap
from $4,940
Up to 30%
EXPLORE

Mekong Discovery - Phnom Penh to Ho Chi Minh

4 Day Itinerary aboard Aqua Mekong
  • Walk through verdant plantations
  • Learn about local traditions
  • Visit Vinh Trang Pagoda
  • Tour Sa Dec markets
Activity Level
Variable
Embark the luxurious Aqua Mekong in Phnom Penh, Cambodia, on this 4-day discovery cruise along the Mekong River to Ho Chi Minh City, Vietnam. You'll peruse vibrant markets and visit typical Mekong Delta villages while getting to know local cultures and ways of life, with a visit to Vinh Trang Pagoda and opportunities to bike along the way.
Cruise Details
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Phnom Penh Royal Palace complex
from $13,190
Save $150
EXPLORE

Luxury Mekong

Siem Reap to Ho Chi Minh City - 8 Day Itinerary aboard Scenic Spirit
  • Explore beauty of Angkor Ban
  • Visit architecture of Phnom Penh
  • Visit the Royal Palace
  • Sail through Vinh Te canal
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Experience an 8-day cruise along the Mekong River from Siem Reap to Ho Chi Minh on the Scenic Spirit, blending cultural exploration with relaxation. Discover historical sites and local traditions while enjoying luxurious comfort and the region's vibrant contrasts.
Cruise Details
0
25-36 of 43 Results

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