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Top Mekong River Trips & Tours in September 2026

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Harvesting rice in Vietnam
from $2,782
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Mekong River - Upstream - High water

Saigon to Siem Reap - 8 Day Itinerary aboard Jayavarman
  • Witness Cai Be Candy Making
  • Discover skilled craftsmanship
  • Experience scenic views at Delta
  • Tour Phnom Penh
  • Discover cultures of Mekong Delta
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Village Visits, Archaeological Site Visits, Cooking Classes
Activity Level
Variable
Embark on an 8-day Mekong River cruise aboard the Jayavarman, from Saigon to Siem Reap. Experience the beauty and culture of the lower Mekong River, explore charming riverside towns, and uncover the rich history and traditions that define this remarkable region.
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Angkor Wat
from $10,950
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Wonders of Cambodia, Vietnam and the Mekong

Siem Reap - Ho Chi Minh - 15 Day Itinerary aboard Emerald Harmony
  • Explore Angkor Thom’s royal city
  • Witness sunrise over Angkor Wat
  • Visit Angkor Ban’s resilient homes
  • Learn Cambodia’s history
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Set sail on a 15-day cruise from Siem Reap to Ho Chi Minh City aboard the Emerald Harmony, exploring Angkor Wat, Phnom Penh, and a Cao Dai temple in Vietnam. Experience local culture, crafts, and a two-night hotel stay in the vibrant Ho Chi Minh City.
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Sunset over the Mekong River
from $15,695
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Treasures of the Mekong

Ho Chi Minh City - Siem Reap - 13 Day Itinerary aboard Scenic Spirit
  • Explore Ho Chi Minh City’s tunnels
  • Visit Cai Be’s orchard island
  • Uncover Sa Dec’s markets
  • Admire Oudong’s serene monastery
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Set sail on a 13-day cruise from Ho Chi Minh City to Siem Reap aboard the Scenic Spirit, exploring the rich culture and history of Vietnam and Cambodia. Enjoy activities like cooking classes, temple tours, and immersive experiences, including a monk’s blessing and a gala dinner.
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Khone Pha Pheng waterfall, a famous waterfall in Southern of Laos
from $1,144
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Southern Laos

Lao's Mekong River - 5 Day Itinerary
  • Explore Wat Phou Ancient Ruins
  • Cruise Mekong River Scenic Islands
  • View Khone Phapheng Massive Falls
  • Cycle Don Khone Peaceful Trails
  • Visit Liphi Cascading Waterfalls
Starts / Ends
Pakse / Pakse
Activity Level
Relaxed
Discover the hidden gems of Southern Laos on this immersive 5-day private adventure. You explore the ancient UNESCO ruins of Wat Phou, cruise the Mekong to the peaceful 4000 Islands, and experience local life with a fishing trip and island BBQ. The trip concludes with the stunning waterfalls and tribal villages of the cool Bolaven Plateau.
Tour Details
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Statues and intricate relief carvings inside Angkor Wat
from $10,950
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Wonders of Vietnam, Cambodia and the Mekong

Ho Chi Minh - Siem Reap - 15 Day Itinerary aboard Emerald Harmony
  • Explore Cu Chi Tunnels
  • Tour Sa Dec’s markets
  • Visit My An Hung village
  • Discover Gieng Island industries
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Local Market Visits, Wildlife Viewing, Land & Sea Exploration
Activity Level
Variable
Set sail on a 15-day cruise aboard Emerald Harmony, starting in Ho Chi Minh City and journeying through the Mekong River to discover villages like My An Hung and iconic sites such as the Cao Dai Temple. Conclude your adventure in Siem Reap, exploring the rich cultural heritage of Cambodia, including the famous Angkor Wat.
Cruise Details
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Explore the floating village of Tonle Sap
from $4,940
Up to 30%
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Mekong Discovery - Phnom Penh to Ho Chi Minh

4 Day Itinerary aboard Aqua Mekong
  • Walk through verdant plantations
  • Learn about local traditions
  • Visit Vinh Trang Pagoda
  • Tour Sa Dec markets
Activity Level
Variable
Embark the luxurious Aqua Mekong in Phnom Penh, Cambodia, on this 4-day discovery cruise along the Mekong River to Ho Chi Minh City, Vietnam. You'll peruse vibrant markets and visit typical Mekong Delta villages while getting to know local cultures and ways of life, with a visit to Vinh Trang Pagoda and opportunities to bike along the way.
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Phnom Penh Royal Palace complex
from $13,590
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Luxury Mekong

Siem Reap to Ho Chi Minh City - 8 Day Itinerary aboard Scenic Spirit
  • Explore beauty of Angkor Ban
  • Visit architecture of Phnom Penh
  • Visit the Royal Palace
  • Sail through Vinh Te canal
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Urban Exploration
Activity Level
Variable
Experience an 8-day cruise along the Mekong River from Siem Reap to Ho Chi Minh on the Scenic Spirit, blending cultural exploration with relaxation. Discover historical sites and local traditions while enjoying luxurious comfort and the region's vibrant contrasts.
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The beautiful Angkor Wat
from $10,890
Up to 30%
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Mekong Expedition - Siem Reap to Ho Chi Minh

8 Day Itinerary aboard Aqua Mekong
  • Visit Prek Toal Core Bird Reserve
  • Sail to floating village Chhnok Tru
  • See Cambodia's capital & sights
  • Meet and interact with locals
Activities
Kayaking
Activity Level
Variable
This 8-day cultural cruise aboard the Aqua Mekong takes you from Siem Reap, Cambodia, to Ho Chi Minh City, Vietnam, stopping at Tonle Sap Lake and other local destinations of interest along the Mekong River. You'll visit Prek Toal Core, sail into Chhnok Tru, a true floating village, and see Cambodia's capital by motorized tuk-tuk.
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The colorful Tonle Sap village
from $6,590
Up to 30%
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Mekong Explorer - Siem Reap to Phnom Penh

5 Day Itinerary aboard Aqua Mekong
  • Visit Prek Toal Core Bird Reserve
  • Meet and interact with locals
  • Attend a Buddhist blessing ceremony
Activity Level
Variable
Embark the Aqua Mekong on this 5-day voyage down the Mekong River from Siem Reap to Phnom Penh. Stop in charming floating villages, interact with the local peoples of the area, and explore the colorful markets and cultural sites which line the shores.
Cruise Details
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Mekong River
from $1,656
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Mekong River - Downstream - High water

Siem Reap to Phnom Penh - 5 Day Itinerary aboard The Jahan
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Cycle historic sites & workshops
Starts / Ends
Siem Reap / Phnom Penh
Activity Level
Variable
Join this 5-day high water river cruise aboard The Jahan from Siem Reap to Phnom Penh, and travel across the mighty Mekong Delta to discover the ancient pre-Angkorian temples and Cambodian culture.
Cruise Details
0
Floating village in Southeast Asia
from $1,685
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Mekong River - Downstream - High water

Siem Reap to Phnom Penh - 5 Day Itinerary aboard Jayavarman
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Try making traditional Khmer snack
Starts / Ends
Siem Reap / Phnom Penh
Activity Level
Variable
From Siem Reap to Phnom Penh, join this 5-day High Water Mekong river cruise aboard the Jayavarman and journey through the vast Mekong Delta to explore the historic pre-Angkorian temples and Cambodian culture.
Cruise Details
0
Young monk in a temple
from $1,656
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Mekong River - Upstream - High water

Phnom Penh to Siem Reap - 5 Day Itinerary aboard The Jahan
  • Observed locals along the river
  • Village visits
  • Immerse in culture
  • Cruise the Mekong River
Starts / Ends
Phnom Penh / Siem Reap
Activities
Biking
Activity Level
Variable
Experience a 5-day High Water Serenity Cruise, from Phnom Penh to Siem Reap, to explore Cambodian culture as you travel through the majestic Mekong delta. Along the way, you visit delightful port towns and indulge in the city's rich heritage and traditions.
Cruise Details
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