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Top Central America & Mexico Tours & Cruises in 2027

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    • Central America & Mexico
Guests explore by zodiac cruise in Portobelo, Panama
from $6,150
Solo Deal
EXPLORE

The Panama Canal, Pearl Islands and Darien Jungle

Southbound - 8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Explore Darien Jungle
  • Visit Portobelo Forts
  • Snorkel Pearl Islands
Starts / Ends
Panama City / Panama City
Activity Level
Variable
Embark on an 8-day Panama Canal, Pearl Islands and Darien Jungle cruise aboard National Geographic. Quest in Colon and explore Panama’s Pacific coast. Cruise Gatun Lake, hike Barro Colorado Island trails, and visit the Pearl Islands. Discover Darien National Park’s rainforest and culture, explore Punta Patiño Reserve, and return to Panama City.
Cruise Details
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Snorkeling among the coral reef system
from $3,925
EXPLORE

Glamping the Seas and Sierras of Baja

8 Day Itinerary
  • Explore diverse Sierra de la Laguna
  • Swim with sea lions & colorful fish
  • Experience rancho culture
  • Discover and be awed by Baja
Starts / Ends
La Paz / La Paz
Activities
Wilderness Lodge Exploration, Camping, Homestays
Activity Level
Relaxed
On this 8-day tour, explore the Sierra La Laguna Biosphere Reserve, La Paz, and Espiritu Santo Island. Admire the marine life on Isla Espiritu Santo, stay in a luxury tent camp in the Sierra, and experience the rancho culture of Baja. Visit La Paz with its world-class beaches, waterfront Malecón, and abundant fresh seafood.
Tour Details
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Aerial view of the summit of Barú volcano, the tallest mountain in Panama at 3,474 meters high
from $3,576
EXPLORE

Discover Panama

8 Day Itinerary
  • Trek the lowland tropical forest
  • Bike, hike, zipline, raft or relax
  • See wildlife in natural habitats
  • Explore Tranquilo Bay
Activities
Biking
Activity Level
Easy Active
This 8-day hotel-based tour of Panama takes you from metropolitan Panama City, through the lowland tropical forest of Soberania National Park, snorkeling, kayaking, hiking, surfing, birding, and exploring Bocas del Toro & Tranquilo Bay, and finally to the Miraflores locks of the Panama Canal.
Tour Details
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Keel-billed Toucan
from $6,230
EXPLORE

Central America Jewels & Panama Canal

Colon to Puntarenas - 8 Day Itinerary aboard Le Laperouse
  • Explore San Blas Islands
  • Discover Historic Portobelo
  • Transit Panama Canal
  • Encounter Costa Rica Wildlife
Starts / Ends
Colon / Puntarenas
Activities
Spa Relaxation
Activity Level
Variable
Explore Panama and Costa Rica on this 8-day voyage from Colón to Puntarenas aboard Le Laperouse. Travel through the Panama Canal, visit the San Blas Islands, Portobelo and Darién National Park, and discover local communities, coastal landscapes and wildlife. The journey also includes time at sea and excursions in Costa Rica’s Osa Peninsula region.
Cruise Details
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Explore beautiful Costa Rica
from $6,125
Solo Deal
EXPLORE

Inland Costa Rica, the Panama Canal and Pearl Islands

San Jose to Panama - 9 Day Itinerary aboard National Geographic Quest
  • Arenal Volcano exploration
  • Relax in Ecotermales hot springs
  • Pearl Islands snorkeling
  • Navigate the Panama Canal
Starts / Ends
San Jose / Panama City
Activities
Stand Up Paddle Boarding, Land & Sea Exploration
Activity Level
Variable
Arrive in San Jose, transfer to La Fortuna and start the 9-day land and sea adventure. Explore Arenal Volcano and rainforest trails. Fly to Panama City and embark National Geographic Quest. Kayak, hike, and cruise the Panama Canal, Gatun Lake, and Pearl Islands while snorkeling, exploring fortresses, and discovering tropical wildlife.
Cruise Details
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Tortuga Island beach
from $7,500
EXPLORE

Costa Rica Unbound

Golfito to Quepos - 8 Day Itinerary aboard M/Y Kontiki Wayra
  • Visit a private beach in Los Mogos
  • Spot wide variety of wildlife
  • See coral reefs in Puerto Jimenez
  • Take a thrilling whitewater rafting
  • Enjoy snorkeling in Biesanz Beach
Starts / Ends
Golfito / Quepos
Activities
Scuba Diving
Activity Level
Variable
Embark on an 8-day luxury cruise on M/Y Kontiki Wayra, exploring Costa Rica's breathtaking Pacific coast. Sail through Golfito, Los Mogos, Punta Adela, Caño Island, Puerto Jiménez, & Corcovado National Park before arriving at Quepos. Experience stunning landscapes, vibrant marine life, pristine beaches, & gourmet dining aboard this exquisite yacht.
Cruise Details
0
Costa Rica Toucan Bird
from $2,010
EXPLORE

Costa Rica to Panama

Puerto Caldera - Balboa - 8 Day Itinerary aboard Star Clipper
  • Explore Puerto Caldera’s coast
  • Relax on Isla Tortuga’s beaches
  • Experience Golfito’s rich history
  • Snorkel in Golfo de Chiriqui’s
Starts / Ends
Puerto Caldera / Balboa
Activities
Ziplining, Small Ship Sailing
Activity Level
Variable
Set sail on an 8-day cruise aboard the Star Clipper, starting in Puerto Caldera, Costa Rica. Explore stunning beaches, vibrant marine parks, and rich history before concluding your adventure in Balboa, Panama.
Cruise Details
0
Ruins in Colon, Panama
from $13,300
EXPLORE

Costa Rica & Panama Coastal Expedition Cruise

Liberia Airport to Panama City - 15 Day Itinerary aboard Safari Voyager
  • Explore Santa Rosa Wilderness
  • Visit Embera Cultural Village
  • Cross Panama Canal
  • Discover Guna Yala Islands
Starts / Ends
Liberia / Panama City
Activities
Snorkeling, Archaeological Site Visits, Rainforest Exploration, Wildlife Viewing, Hiking, Kayaking, Village Visits, Whale Watching
Activity Level
Variable
Experience a 15-day expedition cruise from Liberia, Costa Rica, to Panama City, Panama, aboard Safari Voyager. Explore remote national parks, tropical islands, vibrant reefs, and Indigenous communities while kayaking, snorkeling, hiking, and crossing the iconic Panama Canal on an unforgettable small-ship adventure.
Cruise Details
0
Clear waters of the Caribbean sea
from $7,170
EXPLORE

Panama and Costa Rica by Sea - with Smithsonian Journeys

Puntarenas to Colon - 8 Day Itinerary aboard Le Laperouse
  • Explore Darien National Park
  • Embera village visit
  • See Miraflores Locks view
  • Experience Guna community encounter
Starts / Ends
Puntarenas / Colon
Activity Level
Variable
Set sail on an 8-day cruise from Puntarenas to Colon aboard Le Laperouse. Explore Quepos, Darien National Park, Flamenco Island, the San Blas Islands, and complete the full Panama Canal crossing with cultural encounters and wildlife viewing.
Cruise Details
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Panama Canal
from $5,772
Solo Deal
EXPLORE

Costa Rica and the Panama Canal

Eastbound - 8 Day Itinerary aboard National Geographic Quest
  • Observe animals in their habitat
  • Kayak through magical mangroves
  • Transit the historical Panama Canal
  • Explore Gulf of Panama beaches
Activity Level
Variable
Discover Costa Rica & Panama on this 8-day cruise aboard the National Geographic Quest. Venture into remote wilderness and hike among monkeys, sloths, and tropical birds, explore idyllic islands, snorkel over a vibrant coral reef, and take an expedition landing craft cruise through mangroves.
Cruise Details
0
Beautiful beach of Corcovado National Park
from $4,200
EXPLORE

Pura Vida Express

Golfito to Drake Bay - 5 Day Itinerary aboard M/Y Kontiki Wayra
  • Visit a private beach in Los Mogos
  • See coral reefs in Puerto Jimenez
  • Enjoy water activities
  • Spot wide variety of wildlife
Starts / Ends
Golfito / Drake Bay
Activities
Whitewater Rafting
Activity Level
Variable
Discover the stunning Pacific coast of Costa Rica with a 5-day luxury cruise onboard M/Y Kontiki Wayra. Sail through Golfito, Los Mogos, Puerto Jiménez, Punta Adela, and Corcovado National Park. Experience the breathtaking scenery, abundant marine life, and pristine beaches.
Cruise Details
0
Paradise tropical in Belize Central America
from $1,690
EXPLORE

Treasures of Belize

8 Day Itinerary
  • Explore Lamanai Mayan ruins
  • Stay at a secluded jungle lodge
  • Search for Belizean marine life
  • Choose from a menu of activities
Activities
Fishing
Activity Level
Relaxed
This tour incorporates a secluded jungle stay and a beach getaway on Ambergris Caye at the secluded Lamanai Outpost Lodge. See myriad marine life such as sea turtles, eagle rays, nurse sharks, and hundreds of species of fish. You can also explore the island by bicycle, rent a catamaran, or just relax on the beach! 
Tour Details
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