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Top Main River Cruises & Trips

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Explore these 13 top Main River cruises for 2023 and 2024. Some of the most popular activities on our Main River trips include cruises, river cruises, biking, wine tasting, and village visits. Discover Frankfurt, Wurzburg, Bamberg, Wertheim, and Main River with your expert local English-speaking guides who will show you the hot spots and the off-the-beaten-path hidden gems. We work with only the best small ships that carry under 500 fortunate guests, and we can give you unbiased advice to match you with the perfect ship and perfect cruise for your next vacation. Our Main River cruises start from $2,221 for cruises of 5 to 16 days. Contact one of Adventure Life's Main River cruise specialists for help planning a seamless trip.
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Panoramic view of Budapest cityscape
$3,908
EXPLORE

Trans-European Cruise

Strasbourg to Budapest - 13 Day Itinerary aboard MS France
  • Visit the historical city of Mainz
  • Explore Miltenberg's architecture
  • Enjoy Passau's baroque charm
  • Discover Austrian history
Activities:
Biking, River Cruises, Urban Exploration
Activity Level:
Relaxed
Explore Central Europe from the comfort of your luxury ship during this 13-day voyage aboard the MS France. VisitWürzburg, a magic city situated on the right bank of the Main River, a city famous for its baroque palace. Enjoy aguided tour to Rothenburg, a magnificent walled town set up high on …
Cruise Details
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View of Strasbourg city
$3,299
EXPLORE

Medieval Treasures - Cruise Only

8 Day Itinerary aboard MS Amaprima
  • Explore “La Petite France”
  • Discover Speyer's Cathedral
  • Taste Romerberg's culinary delights
  • Enjoy historical Miltenberg
Activities:
Biking, Hiking, Small Ship Cruises, Wine Tasting
Activity Level:
Relaxed
Marvel at some of Europe’s grandest Baroque jewels at the Würzburg Residenz. Visit one of Mark Twain’s favorite cities, Heidelberg, and meander through Miltenberg, with its half-timbered houses that lean crookedly against one another. Take a gondola ride over Rüdesheim’s …
Cruise Details
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Explore beautiful Amsterdam
$7,395
EXPLORE

Jewels of Europe

Amsterdam to Budapest - 15 Day Itinerary aboard Scenic Pearl
  • Visit the Bishops’ Residenz
  • Discover the Dom cathedral
  • Explore Bamberg Old Town
  • View Prague's architectural marvels
Starts / Ends:
Amsterdam / Budapest
Activities:
Biking, Christmas Market Visits, Hiking, River Cruises, Urban Exploration
Activity Level:
Relaxed
Join the Scenic Pearl on this fascinating cruise from Amsterdam to Budapest and discover European regions rich in ancient trade history. Today, the Rhine, Main, and Danube rivers wind their way through forested ridges, magnificent vineyards, and charming towns. See traditional Dutch windmills in …
Cruise Details
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View of Strasbourg city
$3,799
EXPLORE

Medieval Treasures - Cruise Only

8 Day Itinerary aboard MS Amacerto
  • Explore “La Petite France”
  • Discover Speyer's Cathedral
  • Taste Romerberg's culinary delights
  • Enjoy historical Miltenberg
Activities:
Biking, Hiking, Small Ship Cruises, Wine Tasting
Activity Level:
Relaxed
Marvel at some of Europe’s grandest Baroque jewels at the Würzburg Residenz. Visit one of Mark Twain’s favorite cities, Heidelberg, and meander through Miltenberg, with its half-timbered houses that lean crookedly against one another. Take a gondola ride over Rüdesheim’s …
Cruise Details
0
$3,999
EXPLORE

Rhine & Moselle

Strasbourg to Frankfurt - 10 Day Itinerary aboard River Queen
  • 3 UNESCO World Heritage sites
  • Experience historic Speyer
  • Explore Cochem’s castles
  • Let Moselle and Rhine captivate you
Starts / Ends:
Strasbourg / Frankfurt
Activities:
Archaeological Site Visits, Biking, Land & Sea Exploration, Small Ship Cruises, Village Visits
Activity Level:
Relaxed
Germany’s spectacular backdrops and breathtaking natural wonders will reveal themselves as you cruise along the alluring Moselle and Rhine rivers. SeeStrasbourg, a dynamic city that has changed its nationality four times, has a lot to offer.Savor a one-of-a-kind experience in historic Speyer, …
Cruise Details
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River through Koblenz Germany
$2,221
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The Valley of the romantic Rhine, the Moselle and the Main

Strasbourg Roundtrip - 7 Day Itinerary aboard MS Gérard Schmitter
  • Cruise Iffezheim & Gambsheim locks
  • Enjoy Strasbourg at night
  • Visit the unique Reichsburg Castle
  • Join an exclusive wine tasting
Activities:
River Cruises, Village Visits, Wine Tasting
Activity Level:
Relaxed
Board the MS Gérard Schmitter and discover the authentic European charm as you explore the Rhine, Moselle, and Main Rivers on this exclusive 7-day cruise. Enjoy an exceptional tour of old Strasbourg at night aboard a canal boat. Visit the charming city of Frankfurt and enjoy a guided tour. …
Cruise Details
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Visit castle ruins in the German countryside
$4,599
EXPLORE

Grand European Tour

Amsterdam to Budapest - 15 Day Itinerary aboard Viking Cruises
  • Discove the Dom,Germany’s cathedral
  • Explore Marksburg Castle
  • Visit the Bishops’ Residenz
  • View Germany’s oldest restaurant
Starts / Ends:
Amsterdam / Budapest
Activities:
Biking, Hiking, River Cruises, Urban Exploration
Activity Level:
Relaxed
Embark on your ship in Budapest and discover the Rhine Valley vistas from a 900-year-old castle. Sample the food and wine of Austria’s Wachau Valley. Learn the Viennese waltz and linger in Budapest’s Café Gerbeaud. Indulge all your senses on this 15-day journey spanning the best …
Cruise Details
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Explore the unique architecture of Bamberg
$8,954
EXPLORE

Enchanted Europe

Eastbound - 16 Day Itinerary aboard Avalon Visionary
  • Join a tour in Rüdesheim
  • Enjoy Strasbourg's sights
  • Marvel at the Benedictine Abbey
  • Take a tour of Vienna
  • Taste some good wine on board
Starts / Ends:
Basel / Budapest
Activities:
River Cruises, Village Visits, Wine Tasting
Activity Level:
Relaxed
This river cruise begins in the Rhine River in Basel then will sail to Breisach for a Black Forest excursion and to the city of Strasbourg along the way. Sail to Rüdesheim and through the spectacular Rhine Gorge. The modern and charming city of Frankfurt is also on your route along the Rhine …
Cruise Details
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Explore the inspiring Amsterdam
$3,999
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Remarkable Rhine & Historic Holland

Amsterdam-Basel - 11 Day Itinerary aboard River Empress
  • Visit the Jewish Museum.
  • Visit Kinderdijk village on a tour.
  • Visit Arnhem Airborne Museum WWII
  • Visit Romanesque cathedrals
Starts / Ends:
Amsterdam / Basel
Activities:
Biking, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Board the River Empress and delve into the history and culture of western Europe. Explore bustling cities and quiet villages, admire the stunning scenery of the Rhine River Valley, and wander the region’s world-renowned museums. Along the way, indulge in Central Europe’s delicious …
Cruise Details
0
Place Kleber in Strasbourg
$4,149
EXPLORE

German Grandeur

Eastbound - 9 Day Itinerary aboard Avalon Tranquility II
  • Explore magical Black Forest
  • Discover Mechanical Music Museum
  • Enjoy the visit in wine producer
  • Explore Bamberg
Starts / Ends:
Basel / Nuremberg
Activities:
River Cruises, Village Visits, Wine Tasting
Activity Level:
Relaxed
Your picturesque European river cruise begins on the Rhine River in Basel, Switzerland. You’ll sail to Breisach—with your choice of a visit to Badischer Winzerkeller, or an excursion to the Black Forest. Sail to the city of Strasbourg, France, along the way, and on to the wine village …
Cruise Details
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Basel at Christmas, Switzerland
$2,999
EXPLORE

Christmastime in Alsace and Germany

Northbound - 5 Day Itinerary aboard Avalon Tranquility II
  • Experience the Black Forest
  • Explore Christmas market in Europe
  • Visit Fascinating Heidelberg Castle
  • Tour Strasbourg Cathedral
Starts / Ends:
Basel / Frankfurt
Activities:
Christmas Market Visits, River Cruises
Activity Level:
Relaxed
Board the Avalon Tranquility II on this delightful 5-day cruise exploring the cozy Christmas markets of the towns along the Rhine River. Set off from Basel, Switzerland along the Rhine toward Breisach, Germany, considered a gateway to the legendary Black Forest region. Stroll through the …
Cruise Details
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Explore Basel
$2,428
EXPLORE

Christmastime in Alsace and Germany

Northbound - 5 Day Itinerary aboard Avalon Imagery II
  • Experience the Black Forest
  • Explore cozy Christmas markets
  • Tour historic Heidelberg Castle
  • Visit the Strasbourg Cathedral
Starts / Ends:
Basel / Frankfurt
Activities:
Christmas Market Visits, River Cruises, Small Ship Cruises
Activity Level:
Relaxed
FromSwitzerland and takes you down the Rhine River to France and Germany, with beautiful passing views and quaint villages festively lit and decorated—a unique and unforgettable way to celebrate the season! Board your ship in Basel, Switzerland, then stop in Breisach, considered the gateway …
Cruise Details
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Enjoy a cozy Christmas Market in Frankfurt
$3,599
EXPLORE

Classic Christmas Markets

Nuremberg to Frankfurt - 8 Day Itinerary aboard River Queen
  • Explore Wertheim
  • Christmas market visits
  • Nuremberg tour
Starts / Ends:
Nuremberg / Frankfurt
Activities:
Archaeological Site Visits, Christmas Market Visits, River Cruises, Village Visits, Wine Tasting
Activity Level:
Relaxed
Sail through Christmas country on this 8-day classic holiday cruise aboard River Queen, trying Frankfurt’s famous apple cider and Nuremberg’s gingerbread. Throughout, cozy up to steaming mugs ofglühwein(warm spiced wine) and do as the locals do by collecting different mugs from …
Cruise Details
0
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