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Top Moselle River Trips & Tours in September 2026

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Discover Moselle River in September 2026 on one of these 14 tours hand-selected by the travel experts at Adventure Life. Explore the best of during September 2026 as you enjoy Wine Tasting, Village Visits, Hiking, Biking, and Archaeological Site Visits. Prices for trips in September 2026 range from $1,430 to $82,500 for a vacation of 5 to 15 days. Choose any of the below 14 itineraries in September 2026 and customize it when you contact one of Adventure Life's expert Moselle River trip planners.
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Cochem town on the Mosel River, Germany
from $10,725
EXPLORE

Classic Cruise – Germany & Luxembourg

Koblenz - Remich - 7 Day Itinerary aboard La Nouvelle Etoile
  • Visit Winningen for Mosel wines
  • Tour Cochem castle views
  • Taste Zell wines at Dr Weiss’s cell
  • Discover Trier’s Roman heritage
Activity Level
Variable
Join a 7-day cruise on the La Nouvelle Etoile along the Moselle River from Koblenz to Remich, featuring wine tastings and cultural tours. Explore historic landmarks like Burg Eltz and Trier, culminating in a final dinner in Luxembourg’s capital.
Cruise Details
0
Ehrenfels Castle on Rhine River near Rudesheim
from $1,430
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The Rhine and Moselle Rivers

Strasbourg to Cochem - 5 Day Itinerary aboard MS Monet
  • Tour Mainz and Gutenberg
  • Wine tasting in Rudesheim
  • Explore Boppard
Starts / Ends
Strasbourg / Cochem
Activity Level
Variable
Sail across Strasbourg, Mainz, Rudesheim, Boppard, Koblenz, Alken and Cochem on this spectacular 5-day journey aboard the MS Monet. Discover all the beauty and authentic European charm of this region.
Cruise Details
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Explore historic Bamberg
from $4,849
$2500
EXPLORE

Europe's Rivers & Castles - Cruise Only

Nuremberg - Luxembourg - 8 Day Itinerary aboard MS Amacerto
  • Explore Wurzburg’s Baroque splendor
  • Discover Bamberg’s architecture
  • Stroll Wertheim’s charming streets
  • Visit Rudesheim’s vineyard gondola
Starts / Ends
Nuremberg / Luxembourg
Activities
Hiking
Activity Level
Variable
Set sail on an 8-day river cruise aboard the MS Amacerto, exploring Europe’s charm from the scenic Main River to the Upper Middle Rhine Valley's castles and Moselle's vineyards. Visit picturesque villages like Bernkastel, Cochem, and Rothenburg, admire the Wurzburg Residenz fresco, and savor German wines and smoked beer.
Cruise Details
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River through Koblenz Germany
from $2,348
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The Valley of the romantic Rhine, the Moselle and the Main

Strasbourg Roundtrip - 7 Day Itinerary aboard MS Gérard Schmitter
  • Cruise Iffezheim & Gambsheim locks
  • Enjoy Strasbourg at night
  • Visit the unique Reichsburg Castle
  • Join an exclusive wine tasting
Activity Level
Variable
Explore the enchanting cities of Strasbourg, Frankfurt, Cochem, Koblenz, Rudesheim and Mannheim on this 7-day river cruise aboard the MS Gérard Schmitter. As you travel the Rhine, Moselle, and Main rivers, you'll have the chance to tour ancient towns, bike through verdant valleys, savor the local wines, and explore castles.
Cruise Details
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Historic old town Strasbourg
from $2,043
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4 Rivers: The Moselle, Sarre, Romantic Rhine, and Neckar Valleys (Port-to-port cruise)

Luxembourg to Strasbourg - 7 Day Itinerary aboard MS Leonardo Da Vinci
  • Enjoy a Luxembourg city guided tour
  • Experience wine tasting in Remich
  • Explore Roman sites in Trier
  • Stroll in Koblenz's old town
Starts / Ends
Luxembourg / Strasbourg
Activities
Wine Tasting, Archaeological Site Visits, Village Visits, Urban Exploration
Activity Level
Variable
Embark on a 7-day river cruise aboard MS Leonardo Da Vinci from Luxembourg to Strasbourg along the Moselle, Rhine, and Neckar Rivers. Explore Trier’s Roman heritage, Cochem Castle, Koblenz, Rudesheim vineyards, and Heidelberg’s historic charm. Enjoy wine tastings, guided tours, and lively evenings on board.
Cruise Details
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Strasbourg at dusk
from $1,995
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The Valley of the Romantic Rhine, the Moselle and the Main

Strasbourg Roundtrip - 7 Day Itinerary aboard MS La Boheme
  • Enjoy Strasbourg at night
  • Visit Cochem, Pearl of the Moselle
  • See the unique Reichsburg Castle
  • Discover the famous Lorelei Rock
Starts / Ends
Strasbourg / Strasbourg
Activity Level
Variable
Discover three extraordinary rivers: the enchanting Rhine, the graceful Moselle, and the charming Main, on this incredible 7-day cruise aboard La Boheme exploring this romantic region. Delight yourself with the enchanting city of Frankfurt with its mix of ancient and modern sites that are sure to astonish you.
Cruise Details
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Heidelberg
from $7,619
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Rhine & Moselle Delights

15 Day Itinerary aboard MS Amaprima
  • Cruise tranquil Lake Lucerne
  • Explore Strasbourg on foot
  • Visit Trier, Germany’s oldest city
  • Admire Amsterdam's beauty
Activity Level
Variable
This 15-day Rhine & Moselle River cruise aboard MS Amaprima takes you from Zurich to Basel to Amsterdam, passing through Germany and France along the way. Hike and bike in the lush Rhine Valley, stroll the "Crossroads of Europe" in Strasbourg, and savor the best wines and beers that have made this region famous.
Cruise Details
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Cochem town on the Mosel River, Germany
from $6,029
Save $1500
EXPLORE

The Rhine & Moselle (Northbound)

Basel - Amsterdam - 11 Day Itinerary aboard Avalon Imagery II
  • Explore Black Forest village
  • Visit Strasbourg's Gothic cathedral
  • Discover Heidelberg Castle ruins
  • Taste wine in Bernkastel
Starts / Ends
Basel / Amsterdam
Activities
Biking
Activity Level
Variable
Embark on an 11-day cruise aboard the Avalon Imagery II. Explore the Rhine and Moselle Rivers, starting in Basel. Discover charming cities in Germany, France, and Amsterdam, exploring Breisach, Strasbourg, and the Rhine Gorge while enjoying wine tastings in Bernkastel and a canal cruise in Amsterdam.
Cruise Details
0
Ehrenfels Castle on Rhine River near Rudesheim
from $2,606
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5 Different Rivers: The Rhine, Neckar, Main, Moselle, and Saar (Port-to-port cruise)

Strasbourg to Luxembourg - 9 Day Itinerary aboard MS Leonardo Da Vinci
  • Enjoy Heidelberg Castle guided tour
  • Rudesheim vineyard wine tasting
  • Enjoy Rhine Valley scenic sailing
  • Explore Saarburg’s old town
Starts / Ends
Strasbourg / Remich
Activity Level
Variable
Set sail on a 9-day Rhine and Moselle river cruise from Strasbourg to Luxembourg aboard MS Leonardo Da Vinci. Discover Heidelberg Castle, Mainz Cathedral, and Trier’s Roman ruins. Explore Frankfurt, Rüdesheim’s vineyards, Cochem Castle, and Luxembourg’s historic city center. Enjoy wine tastings, guided tours, and unique cultural landmarks.
Cruise Details
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Cochem
from $4,849
$2500
EXPLORE

Rhine & Moselle Splendors - Cruise Only

Luxembourg - Basel - 8 Day Itinerary aboard MS Amacerto
  • Explore Cochem’s historic castle
  • Cruise Rhine Gorge’s beauty
  • Visit Heidelberg's treasure
  • Taste Rudesheim’s unique coffee
Starts / Ends
Luxembourg / Basel
Activity Level
Variable
Embark on an 8-day river cruise aboard the MS Amacerto. Discover Roman treasures, enchanting folklore, and cultural gems like Strasbourg and Schwetzingen Palace Gardens on this unforgettable journey.
Cruise Details
0
Enjoy time in Dusseldorf
from $7,389
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Vineyards of the Rhine & Moselle

13 Day Itinerary aboard MS Amaprima
  • Explore the Rhine River
  • Admire vibrant Amsterdam
  • Visit a local tavern in Cologne
  • Tour the stunning city of Paris
Starts / Ends
Amsterdam / Paris
Activities
Land & Sea Exploration, Local Market Visits
Activity Level
Variable
On this 13-day cruise aboard MS Amaprima, embark in Amsterdam en route to cosmopolitan Paris. Along the way, admire vineyards and picturesque Rhine castles on your way to charming Rüdesheim. Continue to historic Koblenz and cruise through the world’s steepest vineyards along the Moselle River Valley to quaint Cochem and Bernkastel.
Cruise Details
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Visit charming towns on the Moselle River
from $4,849
EXPLORE

Vineyards of the Rhine & Moselle - Cruise Only

8 Day Itinerary aboard MS Amaprima
  • Tour the romantic Amsterdam
  • Visit Cologne's cathedral
  • Visit Rudesheim's vineyards
  • Admire beautiful castles
Starts / Ends
Amsterdam / Luxembourg
Activity Level
Variable
MS Amaprima hosts this exciting 8-day cruise along the Rhine and Moselle. Explore splendid Cologne with its magnificent dome and admire the picturesque Rhine castles on your way to bustling Frankfurt and medieval Heidelberg. Continue to fascinating Koblenz and cruise the beautiful Moselle River Valley to charming Cochem and lovely Bernkastel.
Cruise Details
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La Nouvelle Etoile Cruising
from $82,500
EXPLORE

Private Charter - Classic Cruise - Germany & Luxembourg

Koblenz - Remich - 7 Day Itinerary aboard La Nouvelle Etoile
  • Tour Trier’s Roman heritage
  • Explore Cochem castle views
  • Visit Winningen for Mosel wines
  • Taste Zell wines at Dr Weiss’s cell
Activity Level
Variable
Join a 7-day private cruise on the La Nouvelle Etoile along the Moselle River from Koblenz to Remich, featuring wine tastings and cultural tours. Explore historic landmarks like Burg Eltz and Trier, culminating in a final dinner in Luxembourg’s capital.
Cruise Details
0
Trier
from $5,659
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Rhine & Moselle Delights - Cruise Only

11 Day Itinerary aboard MS Amaprima
  • Explore “La Petite France”
  • Bike along the Rhine River
  • Discover Porta Nigra's secrets
  • Enjoy the fairytale town of Cochem
Starts / Ends
Basel / Amsterdam
Activity Level
Variable
Begin this exclusive 11-day cruise in Basel and conclude in charming Amsterdam. This voyage includes a large variety of activities so that you can choose how you want to explore the wondrous delights of the Rhine and Moselle River regions.
Cruise Details
0
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