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Stop in Avignon on your cruise of the Rhône river.

Avignon River Cruises

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Experience the charming city of Avignon in France with Adventure Life's 13 diverse cruises for 2025. Join us on a cruise journey through the heart of Provence, where you can explore historic landmarks, picturesque villages, and stunning vineyards along the Rhône River. Discover the rich cultural heritage of Avignon, known for its impressive medieval architecture, vibrant arts scene, and delicious cuisine. From wine tasting to local market visits, each moment offers a unique opportunity to immerse yourself in the beauty and history of this region. Engage in urban exploration, archaeological site visits, and village tours, all while surrounded by the natural splendor that has inspired artists for generations. With options for cultural enthusiasts and food & wine lovers alike, don't miss this chance to delve into the captivating nature, history, and flavors of Avignon. Contact one of Adventure Life's Avignon specialists for help planning your next seamless trip.
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    • Avignon
Warm lights glow through the blue hour in Lyon
from $4,139
CLP
EXPLORE

Colors of Provence - Cruise Only

Lyon - Arles - 8 Day Itinerary aboard MS Amakristina
  • Tour the highlights of Lyon, France
  • Stop at the home of a local vintner
  • Learn about olive farming tradition
  • Take the Artist Experience tour
Starts / Ends
Lyon / Arles
Activity Level
Variable
Embark the MS Amakristina in Arles, France for your week-long cruise through France's legendary wine regions, including Cotes du Rhone, Burgundy and Beaujolais. Enjoy wine tastings, ancient Roman ruins, and medieval villages on this European vacation. Les Baux, Avignon, Viviers, Tournon, and Vienne are all stops before arriving to Lyon, France.
Cruise Details
0
Stop in Avignon on your cruise of the Rhône river.
from $2,799
EXPLORE

Lyon & Provence

Avignon - Lyon - 8 Day Itinerary aboard Viking River Cruises
  • Explore Avignon
  • Experience Arles' vibrant city
  • Visit Viviers’ Old Town
  • Discover Beaujolais
Starts / Ends
Avignon / Lyon
Activity Level
Variable
Join this 8-day expedition and tour lands of fine wine & cuisine from Avignon to Lyon aboard Viking River Cruises. Explore Avignon’s Palace of the Popes and excite your palate in Lyon, capital of French gastronomy.
Cruise Details
0
Famous view of Lyon, France
from $13,690
2for1
EXPLORE

Spectacular South of France

11 Day Itinerary aboard Scenic Sapphire
  • Tour St. Rémy & St. Paul de Mausole
  • Enjoy a concert at Palais des Papes
  • Explore Château de Cormatin
  • Explore Lyon
Starts / Ends
Lyon / Lyon
Activity Level
Variable
Enjoy this 11-day luxury round-trip cruise from Lyon aboard Scenic Sapphire. Visit Lyon, Avignon, Viviers and Beaune to explore the centuries-old architecture of Southern France. Sample the celebrated wines and other gastronomic delights for a full South of France experience.
Cruise Details
0
Sprawling vineyards of France
from $6,914
EXPLORE

Colors of Provence

14 Day Itinerary aboard MS Amakristina
  • Enjoy Lyon's culinary delights
  • Visit the Beaujolais wine region
  • Join a Provencal cooking lesson
  • Admire Antoni Gaudi’s works
Starts / Ends
Paris / Barcelona
Activity Level
Variable
This 14-day cruise of France & Spain is a splash of cultures - spend 3 nights in Paris, then travel by high-speed TGV train to Lyon and start on a lovely cruise through Provence onboard MS Amakristina. Then catch the TGV to Spain for 3 nights in Barcelona. Enjoy wine tasting, riding, cooking workshops, and archaeology.
Cruise Details
0
Stop in Avignon on your cruise of the Rhône river.
from $3,799
EXPLORE

Burgundy & Provence

Arles to Lyon - 8 Day Itinerary aboard S.S. Catherine
  • Discover Arles’ Roman ruins
  • Visit Avignon's Palace of the Popes
  • Learn about silk weaving at Lyon
  • Visit Beaune’s Hospices
Starts / Ends
Arles / Lyon
Activity Level
Variable
Embark on an 8-day Burgundy & Provence cruise from Arles to Lyon aboard the S.S. Catherine. Visit towns like Avignon, where medieval charm and the majestic Palace of the Popes await. Next, explore the quaint village of Viviers and its storied past, and then explore the twin wine villages of Tain-l’Hermitage and Tournon.
Cruise Details
0
Discover the history and art of Barcelona
from $5,669
EXPLORE

Essence of Burgundy & Provence

14 Day Itinerary aboard MS Amacello
  • Discover Geneva’s vibrant history
  • Explore Annecy’s picturesque charm
  • Stroll Dijon’s medieval streets
  • Visit Tournus’ Benedictine abbey
Starts / Ends
Geneva / Nice
Activity Level
Variable
Embark on a 14-day cruise aboard the Amacello through Switzerland and France, from Geneva and Annecy through Burgundy and Provence. Indulge in Lyon’s culinary delights, explore historic treasures, and end with three unforgettable nights in Nice, Monaco, and Monte Carlo.
Cruise Details
0
Cruise the Rhone river in charming Lyon
from $1,350
EXPLORE

The tip of Provence to Lyon on the Rhone and Saone River

7 Day Itinerary aboard MS Rhone Princess
  • Discover the Vercors Massif
  • The Camargue and its customs
  • Visit Avignon's Papal Palace
  • Explore Beaujolais
Starts / Ends
Martigues / Macon
Activity Level
Variable
On MS Rhone Princess, embark on an exceptional seven-day cruise from the Rhône to the Saône River. Marseille's Mediterranean port, a safari through the wild Camargue, and a visit to the Beaujolais wineries are among the highlights.
Cruise Details
0
Cruise the Rhone river in charming Lyon
from $4,609
EXPLORE

Active & Discovery on the Rhone

Southbound - 8 Day Itinerary aboard Avalon Poetry II
  • Explore Lyon’s hidden passageways
  • Discover Tournon’s medieval city
  • Taste chocolate in Tain-l’Hermitage
  • Visit Avignon’s iconic Palace
Starts / Ends
Lyon / Arles
Activities
Kayaking
Activity Level
Variable
Embark on an 8-day cruise aboard the Avalon Poetry II, where each port offers exciting adventures and options. Explore Provence’s stunning lavender fields, picturesque bike routes, wine caves, and art-inspired experiences from Lyon to Arles.
Cruise Details
0
Visit colorful Lyon
from $11,590
2for1
EXPLORE

Idyllic Rhone

Nice - Lyon - 8 Day Itinerary aboard Scenic Sapphire
  • Visit the beautiful city of Lyon
  • Explore the region of Beaujolais
  • Uncover the history of Vienne
  • Explore the ancient town of Viviers
Starts / Ends
Lyon / Nice
Activities
Cooking Classes, Urban Exploration
Activity Level
Variable
Enjoy an exceptional Scenic Culinaire experience as you sail from Tarascon to Lyon along the Rhône and Saone rivers aboard the luxurious Scenic Sapphire. Visit the Notre Dame Basilica in Lyon for breathtaking views over one of the most beautiful regions of France, renowned for its art and food.
Cruise Details
0
Arles overview
from $7,590
2for1
EXPLORE

Sensations of Lyon and Provence

Lyon - Marseille - 8 Day Itinerary aboard Emerald Liberté
  • Explore Lyon
  • Discover Chalon-sur-Saône
  • Experience Tournon
  • Uncover the rich history of Arles
Starts / Ends
Lyon / Marseille
Activity Level
Variable
Sail from Marseille to Lyon for another fun and exciting 8-day cruise along the Rhone and Saone Rivers. Emerald Liberté offers comfortable accommodations before exploring different cities.
Cruise Details
0
The architectures of Lyon
from $4,139
CLP
EXPLORE

Essence of Burgundy & Provence - Cruise Only

8 Day Itinerary aboard MS Amacello
  • Explore Chalon-Sur-Saone's heritage
  • Discover Tournus’ Romanesque abbey
  • Experience Arles’ Roman ruins
  • Stroll through Beaune’s cobblestone
Starts / Ends
Dijon / Arles
Activity Level
Variable
Embark on an 8-day cruise aboard the MS Amacello through Burgundy and Provence, savoring French flavors and exploring Roman heritage, charming towns, and iconic sites like Lyon’s culinary treasures and Avignon’s Papal Palace.
Cruise Details
0
Panoramic view of Paris
from $7,899
CLP
EXPLORE

Grand Seine and Rhone - Cruise Only

Paris - Arles - 15 Day Itinerary aboard MS Amalyra
  • Visit Les Andelys Chateau Gaillard
  • Discover Honfleur’s harbor
  • Experience Normandy’s beaches
  • Explore Monet’s Giverny gardens
Starts / Ends
Paris' Seine River / Arles
Activities
Biking, Village Visits, Hiking, Archaeological Site Visits, Local Market Visits, Wine Tasting
Activity Level
Variable
Set sail on a 15-day cruise from Paris to Arles on the MS Amalyra, exploring iconic regions along the Seine, Saone, and Rhone rivers. Enjoy historical sites, exquisite wines, and culinary delights, culminating in the vibrant city of Arles.
Cruise Details
0
Warm lights glow through the blue hour in Lyon
from $11,590
2for1
EXPLORE

Idyllic Rhône

Lyon-Tarascon - 8 Day Itinerary aboard Scenic Sapphire
  • Visit the beautiful city of Lyon
  • Explore the region of Beaujolais
  • Uncover the history of Vienne
  • Explore the ancient town of Viviers
Starts / Ends
Lyon / Avignon
Activity Level
Variable
From Lyon to Avignon, cruise along the Rhône and Sâone rivers aboard the luxurious Scenic Sapphire and enjoy an exclusive Scenic culinaire experience. Explore Provence, one of the most beautiful regions of France, known for its art and cuisine.
Cruise Details
0
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