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Wertheim River Cruises

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Set on the tranquil Main River in central Germany, the quaint town of Wertheim is a charming port between the Wurzburg, Mainz, and Rudesheim. The town itself is known for its artisan glass making and beautiful medieval architecture. Visitors to Wertheim can explore the city in a number of ways - bike tours along the Main River are a great active way to see the area; a walking tour of the city will acquaint you with its history and culture; and foodies will enjoy the tour of a local bakery, where you can sample a fresh pretzel. Many of the Main River cruises visiting Wertheim also cruise the Rhine and Danube Rivers. Let us know when you're ready to start planning your Main River cruise experience in Wertheim.
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Top 10 Rhine River Cruises of Wertheim for 2025-2026

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Explore historic Bamberg

Europe's Rivers & Castles - Cruise Only

8 Days from $4,449
Set sail on an 8-day river cruise aboard the MS Amacerto, exploring Europe’s charm from the scenic Main River to the Upper Middle Rhine Valley's castles and Moselle's vineyards. Visit picturesque villages like Bernkastel, Cochem, and Rothenburg, admire the Wurzburg Residenz fresco, and savor German wines and smoked beer.
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Historic Nuremberg

Classic Christmas Markets

8 Days from $4,999
During this 8-Day main river cruise aboard S.S Elisabeth, Celebrate the holidays on a festive Christmas Market from Nuremberg to Frankfurt. Discover traditional markets, sample local holiday treats, and experience celebrations on a luxurious holiday-season voyage.
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Visit old town Frankfurt

Classic Christmas Markets

8 Days from $4,599
During this 8-day main river cruise aboard S.S. Emilie, experience the best of Germany’s Classic Christmas markets on traditions on this magical river cruise from Nuremberg to Frankfurt. Discover sample local holiday treats, and experience celebrations on a luxurious holiday-season voyage.
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Rathaus in Vienna

Magnificent Europe - Cruise Only

15 Days from $7,499
Embark on a 15-day cruise from Budapest to Amsterdam aboard the MS Amastella, sailing the Danube, Main, and the Rhine through five captivating countries. Explore UNESCO treasures, savor Rieslings, enjoy European cuisine, and adventure through scenic landscapes.
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Visit charming Passau

Magnificent Europe

17 Days from $8,449
Embark on a 17-day cruise aboard the MS Amastella, exploring three iconic rivers across five countries. Discover UNESCO World Heritage treasures like Cologne’s Cathedral, Würzburg Palace, and Melk Abbey, while enjoying fine wines, diverse cuisines, and scenic hikes and bike rides in Passau and Vienna.
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Frauenkirche church in Nuremberg

Europe's Rivers & Castles

14 Days from $6,814
Embark on a 14-day cruise with 3 nights in Prague and Paris aboard the MS Amaprima. Explore castle-lined shores, storybook villages, and historic treasures while savoring Germany’s famed wines, beers, and Rüdesheim coffee.
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Enjoy a quiet moment on the banks of the Danube

Splendours of Europe

15 Days from $12,190
Embark on a 14-day river cruise on the Emerald Dawn, starting in Budapest and exploring cities like Vienna, Wurzburg, and Cologne along the Danube, Rhine, and Main rivers. Experience guided tours and unique cultural highlights, culminating in Amsterdam's vibrant atmosphere.
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Explore the inspiring Amsterdam

Grand European Tour: Budapest to Amsterdam

15 Days from $4,999
Join this 15-day Grand European Tour from Amsterdam to Budapest. Explore the beauty, nature, and architecture of Netherlands, Germany, Austria, and Hungary while sailing along the Danube, Main and Rhine Rivers.
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Explore the unique architecture of Bamberg

European Jewels

15 Days from $6,999
Sail the Danube on a 15-day river cruise from Budapest to Amsterdam aboard the River Duchess. Explore historic cities, stunning landscapes, and cultural treasures with expert-guided tours, wine tastings, and local experiences.
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Budapest, the capital city of Hungary

Ultimate European Journey

24 Days from $11,999
Embark on a 24-day cruise from Amsterdam to Bucharest aboard the River Duchess. Sail through eight nations, visit five capital cities, and explore UNESCO sites like Cologne Cathedral and the Rhine Valley.
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2 Best Deals for Rhine River Cruises visiting Wertheim, Germany for 2025-2026

Trip Name From Days Summary
Splendours of Europe $12,190 15 Embark on a 14-day river cruise on the Emerald Dawn, starting in Budapest and exploring cities like Vienna, Wurzburg, and Cologne along the Danube, Rhine, and Main rivers. Experience guided tours and unique cultural highlights, culminating in Amsterdam's vibrant atmosphere.
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Europe's Rivers & Castles - Cruise Only $4,449 8 Set sail on an 8-day river cruise aboard the MS Amacerto, exploring Europe’s charm from the scenic Main River to the Upper Middle Rhine Valley's castles and Moselle's vineyards. Visit picturesque villages like Bernkastel, Cochem, and Rothenburg, admire the Wurzburg Residenz fresco, and savor German wines and smoked beer.
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Wertheim Travel Guide

Highlights of Wertheim, Germany
As you cruise the Rhine River in Germany, enjoy the splendid little port town of Wertheim, considered one of Germany's most beautiful cities and tucked between bigger cities like Frankfurt and Nuremberg. Your time in Wertheim may include activities like:
  • A pretzel making demonstration and tasting
  • Guided bike tours of the countryside
  • Hikes along the banks of the Rhine River
After your tour of Wertheim, your cruise will continue on to other destinations like Rudesheim, Cologne, Wurzburg, Bamberg, Regensburg, and even perhaps the neighboring countries of Belgium to the north or Austria, Slovakia, and Hungary to the south if your Rhine River cruise also includes several days on the blue Danube River.

Want to visit Europe during a unique season? Consider a cruise to Wertheim during the early winter months of November and December to see the incredible displays at the Christmas Markets set up in the Old Towns of most cities along the Rhine in Germany.
Romantic evening light on the Rhine

Europe’s Top Rivers for Cruises

From the comfort of modern and elegant river vessels, travelers no longer have to worry about packing and unpacking their suitcases at every hotel, long haul train and bus rides between destinations, or uncertainty about where they’ll have their next meal - Adventure Life’s hand-picked European River cruises offer all-inclusive experiences along the most interesting waterways of Europe.
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Explore Basel

Best Time to Take a Main River Cruise (Germany)

The Main River of southern Germany connects the Danube River to the east with the Rhine River to the northwest. As the Rhine?s largest tributary and the primary artery between two of Europe?s longest rivers, cruises that include the Main River are usually a bit longer - between 7 days and three weeks, crossing central Europe.
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Romantic evening light on the Rhine

Best Times to Cruise the Rhine

Late April to early June and September to early October are widely considered the best times to cruise the Rhine River due to ideal weather and crowds, though cruise prices are correspondingly higher during these periods. That said, the decision of when to take a Rhine River cruise is largely a personal preference of weather.
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