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Top Mississippi Tours & Cruises in 2026

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Discover Mississippi in 2026 on one of these trips hand selected by the travel experts at Adventure Life. Select any of the below 6 top-rated trips where you will explore Natchez, and Vicksburg with an exceptional bilingual guide on a small group or customizable private tour. The most popular things to do in Mississippi in are cruises, river cruises, urban exploration, cultural, and archaeological site visits. Our Mississippi trips in 2026 range in price from $3,475 to $29,435 for trips of 8 to 23 days. Contact one of Adventure Life's expert Mississippi trip planners for help planning a seamless experience.
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Explore historic New Orleans
$4,190
Savings
EXPLORE

Historic Mississippi River Cruise

New Orleans Roundtrip - 8 Day Itinerary aboard American Melody
  • Explore the antebellum of Natchez
  • Visit historic Civil War sites
  • Discover Oak Alley's historic charm
  • Visit charming ports and cities
Starts / Ends:
New Orleans / New Orleans
Activities:
River Cruises, Urban Exploration
Activity Level:
Variable
Board American Melody for this 8-day cruise along the Mississippi River. Explore unique sites and attractions, admiring the beauty of the world on a roundtrip river cruise from New Orleans. Uncover the history of Oak Alley Plantation, Baton Rouge's dynamic blend of history and modernity, and …
Cruise Details
0
Visit Louisiana's capital city of Baton Rouge
$3,475
Savings
EXPLORE

Historic Mississippi River Cruise

New Orleans Roundtrip - 8 Day Itinerary aboard American Heritage
  • Explore the antebellum of Natchez
  • Visit historic Civil War sites
  • Discover Oak Alley's historic charm
  • Visit charming ports and cities
Starts / Ends:
New Orleans / New Orleans
Activities:
River Cruises, Urban Exploration
Activity Level:
Variable
Board American Heritage for this 8-day cruise along the Mississippi River. Explore unique sites and attractions, admiring the beauty of the world on a roundtrip river cruise from New Orleans. Uncover the history of Oak Alley Plantation, Baton Rouge's dynamic blend of history and modernity, and …
Cruise Details
0
Memphis, Tennesse, USA downtown cityscape at dusk over Beale Street
$5,190
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Melody
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a captivating 9-day cruise aboard the American Melodyfrom Memphis to New Orleans, navigating the mighty Mississippi River. Explore Memphis' musical legacy and vibrant culture before cruising through days of enchanting river views. Vicksburg unfolds its Civil War history, Natchez …
Cruise Details
0
Visit historic Memphis, Tennessee
$5,190
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Symphony
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a captivating 9-day cruise aboard the American Symphonyfrom Memphis to New Orleans, navigating the mighty Mississippi River. Explore Memphis' musical legacy and vibrant culture before cruising through days of enchanting river views. Vicksburg unfolds its Civil War history, Natchez …
Cruise Details
0
Visit Louisiana's capital city of Baton Rouge
$4,530
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Heritage
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a captivating 9-day cruise aboard the American Heritagefrom Memphis to New Orleans, navigating the mighty Mississippi River. Explore Memphis' musical legacy and vibrant culture before cruising through days of enchanting river views. Vicksburg unfolds its Civil War history, Natchez …
Cruise Details
0
Visit historic Minneapolis
$15,640
Savings
EXPLORE

Complete Mississippi River

New Orleans - St. Paul - 23 Day Itinerary aboard American Melody
  • Explore Natchez's Grand Homes
  • Visit Oak Alley
  • Delve into Baton Rouge's history
  • Unravel Vicksburg's Civil War
Starts / Ends:
New Orleans / St. Paul
Activity Level:
Variable
Embark on a 23-day Mississippi River cruise, spanning 10 states on the American Melody. Explore the cultural tapestry of the Mighty Mississippi, touching on history, charm, and scenic landscapes. From lively New Orleans to Minneapolis, discover Baton Rouge's history, St. Francisville's …
Cruise Details
0
1-6 of 6 Results

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