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United States River Cruises

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Columbia River
Sunrise over Crown Point at Columbia River
Cumberland River
Explore historic Nashville, Tennessee
Florida
Fort Lauderdale strip aerial view
Hawaii
Halawa Bay on Molokai
Illinois River
Aerial views of Chicago
United States
Kayaking
New England
Springtime in Boston
Ohio River
Pacific Northwest
Bridge over Columbia River to Mount Hood
Tennessee River
Washington
Explore the landscape of the Pacific northwest
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Discover the glorious beauty of the United States on a river cruise with Adventure Life in 2025. With 34 diverse tours available, ranging from 6 to 23 days in length, you can sail through iconic American landscapes, cities, and cultural sites. Navigating the country's waterways offers a unique perspective, allowing you to discover the beauty of the Mississippi River, the Columbia and Snake Rivers, or even the Intracoastal Waterway. Wildlife enthusiasts will delight in the opportunity for wildlife viewing, while history buffs can explore archaeological sites along the riverbanks. Adventure Life river cruise experts can match you up on the best US river cruise for every traveler's taste. Visit the United States and contact us for help planning your next seamless adventure.
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Sunrise at Crown Point, Columbia River Gorge, Oregon
from $3,675
EXPLORE

Columbia and Snake Rivers: Food, Wine, and History

Portland - Clarkston - 6 Day Itinerary aboard National Geographic Sea Lion
  • Sail under Portland’s iconic bridge
  • See majestic Multnomah Falls
  • Taste wine in charming Walla Walla
  • Visit historic Whitman Mission site
Starts / Ends
Portland / Clarkston
Activity Level
Variable
Experience a 6-day cruise on the Columbia and Snake rivers aboard the National Geographic Sea Lion, and savor exquisite local cuisine and wines curated by Food & Wine's Ray Isle. Explore stunning landscapes through guided hikes and kayaking while learning about the region's rich history and geology from expert naturalists.
Cruise Details
0
Wander through the historic French Quarter
from $3,499
EXPLORE

New Orleans & Southern Charms

Roundtrip New Orleans - 8 Day Itinerary aboard Viking Mississippi
  • Enjoy Cajun and Creole cuisine
  • Indulge in New Orleans' music
  • Learn the history of Vicksburg
  • See the historic homes of Natchez
Starts / Ends
New Orleans / New Orleans
Activities
Festival Visits, Cooking Classes
Activity Level
Variable
Explore the highlights of the Mississippi River on this 8-day cruise roundtrip from New Orleans aboard Viking Mississippi. Discover port cities such as St. Francisville, Darrow, Baton Rouge, Natchez, and Vicksburg to experience the diverse culture and rich history of the lower Mississippi region.
Cruise Details
0
Visit historic St. Louis
from $5,499
EXPLORE

Heartland of America

Missouri to Minnesota - 8 Day Itinerary aboard Viking Mississippi
  • Walk Mark Twain’s Hannibal
  • Explore John Deere innovations
  • Explore historic Burlington charm
  • Explore ancient mound builders
Starts / Ends
St. Louis / St. Paul
Activities
Hiking
Activity Level
Variable
Discover America’s heartland on an 8-day Viking Mississippi cruise from Alton to Red Wing, exploring St. Louis, Hannibal, Burlington, the Quad Cities, Dubuque, and La Crosse. From Mark Twain’s hometown to the Mississippi River Museum, each stop offers a direct look into the nation’s past.
Cruise Details
0
Explore beautiful Nashville
from $5,499
EXPLORE

Nashville, Memphis & the Cumberland

Memphis to Nashville - 8 Day Itinerary aboard Viking Mississippi
  • Discover Memphis blues roots
  • See Paducah murals
  • Walk historic Clarksville streets
  • Cruise Tennessee River scenery
Starts / Ends
Memphis / Nashville
Activity Level
Variable
Take an 8-day Viking Mississippi cruise through Memphis, Cape Girardeau, Paducah, Clarksville, and Nashville. Visit key cultural and historical sites, from music landmarks to Civil War history and regional museums.
Cruise Details
0
View the iconic arch when you visit St. Louis, gateway to the west
from $11,999
EXPLORE

America’s Great River

St. Paul to New Orleans - 15 Day Itinerary aboard Viking Mississippi
  • Explore St. Louis' arts scene
  • Enjoy American music styles
  • Learn Civil War history
  • Experience New Orleans' culture
  • Visit the Quad Cities
Starts / Ends
St. Paul / New Orleans
Activity Level
Variable
Cruise America's great river on this 15-day itinerary aboard Viking Mississippi. Journey from St. Paul, Minnesota to New Orleans, Louisiana and explore highlights of the mighty Mississippi River. Along the way, visit historic ports such as St. Louis, Memphis, Baton Rouge, and more.
Cruise Details
0
Grinnell Valley in Glacier National Park
from $13,915
Savings
EXPLORE

National Parks & Legendary Rivers

Portland, OR to Jackson, WY - 16 Day Itinerary aboard American Jazz
  • Cruise Columbia River Gorge
  • Visit Mount St. Helens
  • Enjoy Richland wine tastings
  • Discover Yellowstone’s geysers
Starts / Ends
Portland / Grand Teton National Park
Activities
Local Market Visits, Kayaking, Land & Sea Exploration
Activity Level
Variable
Embark on a 16-day combined Columbia and Snake Rivers cruise aboard American Jazz and land tour through iconic national parks, Glacier, Yellowstone, and Grand Teton National Parks. Explore vibrant towns, hike scenic trails, visit historic landmarks, and enjoy wine tastings, nature tours, and enriching excursions.
Cruise Details
0
Enjoy stunning views of Portland
from $6,355
Savings
EXPLORE

Columbia & Snake Rivers Cruise

Portland - Clarkston - 9 Day Itinerary aboard American Jazz
  • Astoria historic exploration
  • Learn Mount St. Helens eruption
  • Explore The Dalles museums
  • Richland heritage tour
Starts / Ends
Portland / Clarkston
Activity Level
Variable
Embark on a 9-day cruise aboard American Jazz, navigating the Columbia & Snake Rivers. Cruise past Mount Hood and Mount St. Helens, reliving the golden age of riverboats. Explore Astoria's Victorian charm and visit Fort Clatsop. Journey through history in The Dalles, Richland, and Pendleton, culminating in the majestic landscapes of Hells Canyon.
Cruise Details
0
Tour colorful, historic Charleston, South Carolina
from $6,575
Savings
EXPLORE

Southeast Sea Islands Cruise

Charleston to Amelia Island - 9 Day Itinerary aboard American Liberty
  • Tour historic Charleston homes
  • Explore Beaufort’s Cypress Wetlands
  • Visit Mighty Eighth Museum
  • Walk Savannah’s historic district
Starts / Ends
Charleston / Amelia Island
Activity Level
Variable
Cruise the southeastern coast on a 9-day voyage from Charleston, South Carolina to Amelia Island, Florida, aboard American Liberty. Explore Savannah, Beaufort, Hilton Head, and more.
Cruise Details
0
Columbia River Gorge
from $6,060
Savings
EXPLORE

Columbia & Snake Rivers Cruise

Portland - Clarkston - 9 Day Itinerary aboard American Song
  • Explore Astoria's Victorian charm
  • Step ashore in Kalama
  • Discover Richland's scenic trails
  • Cruise the legendary Snake River
Starts / Ends
Portland / Clarkston
Activity Level
Variable
Embark on a 9-day cruise aboard American Song, navigating the Columbia & Snake Rivers. Cruise past Mount Hood, reliving the golden age of riverboats. Explore Astoria's Victorian charm and visit Fort Clatsop. Journey through history in The Dalles, Richland, and Pendleton, culminating in the majestic landscapes of Hells Canyon.
Cruise Details
0
Bridge across the Mississippi at Cape Girardeau
from $5,275
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Symphony
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends
Memphis / New Orleans
Activity Level
Variable
Experience a 9-day cruise aboard American Symphony from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.
Cruise Details
0
Vibrant Sunset with St. Paul City Skyline and Mississippi Riverfront
from $5,635
Savings
EXPLORE

Upper Mississippi River

St. Paul, MN - St. Louis, MO - 9 Day Itinerary aboard American Serenade
  • Tour historic Summit Avenue
  • Explore Dubuque River Museum
  • Experience John Deere Pavilion
  • Visit Mark Twain’s boyhood home
Starts / Ends
St. Paul / St. Louis
Activities
Village Visits, Urban Exploration, Archaeological Site Visits, Wine Tasting, Wildlife Viewing, Biking
Activity Level
Variable
Set sail for 9 days aboard American Serenade from St. Paul to St. Louis. Walk through historic Summit Avenue, admire La Crosse from Grandad’s Bluff, explore Dubuque’s River Museum, and discover Mark Twain’s legacy in Hannibal. Experience curated onboard programs, live music, and the beauty of the Upper Mississippi’s diverse wildlife.
Cruise Details
0
Columbia River Gorge
from $5,240
Savings
EXPLORE

Columbia & Snake Rivers Cruise

Portland to Clarkston - 9 Day Itinerary aboard American West
  • Explore Astoria's Victorian charm
  • Step ashore in Kalama
  • Discover Richland's scenic trails
  • Cruise the legendary Snake River
Starts / Ends
Portland / Clarkston
Activity Level
Variable
Embark on a 9-day cruise aboard American West, navigating the Columbia & Snake Rivers. Cruise past Mount Hood and Mount St. Helens, reliving the golden age of riverboats. Explore Astoria's Victorian charm and visit Fort Clatsop. Journey through history in The Dalles, Richland, and Pendleton, culminating in the majestic landscapes of Hells Canyon.
Cruise Details
0
Columbia River
from $3,890
Savings
EXPLORE

Columbia River Gorge Cruise

Roundtrip Portland - 7 Day Itinerary aboard American Pride
  • Discover Hood River’s museums
  • Walk through The Dalles
  • Visit Mount St. Helens
  • Taste local wines from Hood River
Starts / Ends
Portland / Portland
Activities
Small Ship Sailing
Activity Level
Variable
Set sail on a 7-day Columbia River Gorge cruise aboard American Pride. Explore Portland, Hood River, The Dalles, and Kalama. Discover the pioneers at the Oregon Trail’s end and learn about the region’s history at museums like the Columbia Gorge Discovery Center and the Fort Dalles Museum.
Cruise Details
0
Visit Louisiana's capital city of Baton Rouge
from $3,630
Savings
EXPLORE

Historic Mississippi River Cruise

New Orleans Roundtrip - 8 Day Itinerary aboard American Heritage
  • Experience Natchez’s beauty
  • Visit historic Civil War sites
  • Discover Oak Alley's historic charm
  • Visit charming ports and cities
Starts / Ends
New Orleans / New Orleans
Activity Level
Variable
The American Heritage hosts this 8-day Mississippi River cruise from New Orleans. Explore historic plantations, Civil War sites, and charming towns. Immerse in the rich culture, cuisine, and music of the Deep South.
Cruise Details
0
Vibrant Sunset with St. Paul City Skyline and Mississippi Riverfront
from $12,620
Savings
EXPLORE

Grand Heartland Cruise

Minnesota - Louisiana - 16 Day Itinerary aboard American Serenade
  • Visit mansions and art galleries
  • See the Gateway Arch and St. Louis
  • Visit Natchez’s antebellum homes
  • Experience Memphis' musical legacy
Starts / Ends
St. Paul / New Orleans
Activity Level
Variable
Embark on a 16-day Mississippi River cruise from Minnesota to Louisiana aboard American Serenade, exploring St. Paul to New Orleans with stops in La Crosse, Dubuque, Davenport, Hannibal, St. Louis, Memphis, Vicksburg, and Natchez. Enjoy onboard activities, stunning scenery, and experiences like the Mark Twain Boyhood Home and more.
Cruise Details
0
View monuments from the Civil War in Mississippi
from $4,610
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Heritage
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends
Memphis / New Orleans
Activity Level
Variable
Experience a 9-day cruise aboard American Heritage from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.
Cruise Details
0
View the iconic arch when you visit St. Louis, gateway to the west
from $9,240
Savings
EXPLORE

Grand Ohio River Cruise

Pittsburgh to St. Louis - 16 Day Itinerary aboard American Melody
  • Explore historic Marietta, Ohio
  • Explore Maysville’s Railroad
  • Visit Louisville’s Churchill Downs
  • Tour Paducah’s wall murals
Starts / Ends
Pittsburgh / St. Louis
Activity Level
Variable
Sail from Pittsburgh to St. Louis on a 16-day Ohio River cruise aboard American Melody. Visit historic towns like Marietta, Cincinnati, Louisville, and Paducah. Discover museums, landmark sites, and cultural excursions while enjoying daily enrichment programs and scenic cruising.
Cruise Details
0
Natchez
from $3,999
EXPLORE

Mississippi Delta Explorer

New Orleans - Memphis - 8 Day Itinerary aboard Viking Mississippi
  • Explore Darrow
  • Visit Natchez historic sites
  • Learn the history of Vicksburg
  • Culinary adventure of Mississippi
  • Know the history of rock 'n' roll
  • American South's Cultural Heritage
Starts / Ends
New Orleans / Memphis
Activity Level
Variable
On this 8-day Mississippi Delta Explorer from New Orleans to Memphis aboard the Viking Mississippi, visit historic towns like Darrow, Natchez, and Vicksburg. Enjoy Cajun and Creole cuisine, Memphis barbecue, and explore the South’s rich history, culture, and music.
Cruise Details
0
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