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Top Southeast Asia Trips & Tours

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Select one of the below 121 best Southeast Asia trips for 2025 and 2026. Your local English-speaking guide will lead your small group or personalized private tour on an extraordinary adventure exploring Phnom Penh, Ho Chi Minh City, Siem Reap, Kampong Chhnang, and My Tho. Our Southeast Asia trips for 2025 feature Local Market Visits, Village Visits, Archaeological Site Visits, Biking, and Wildlife Viewing, and start from $166 for trips of 5 to 16 days. Contact Adventure Life's Southeast Asia trip planning experts to start planning your next seamless trip.
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Royal Palace in Phnom Penh
from $7,490
2for1
EXPLORE

Majestic Mekong River Cruise

Ho Chi Minh City - Phnom Penh - 8 Day Itinerary aboard Emerald Harmony
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
This 8-day cruise exploration hosted by Emerald Harmony takes you to the majestic Mekong River that teaches you to embrace and appreciate Vietnam and Cambodia.
  • Walk around Sa Dec
  • Explore Phnom Penh
  • Discover My An Hung Island
  • Visit Long Khan Island
Cruise Details
0
Explore the floating village of Tonle Sap
from $10,290
NO SS
EXPLORE

Mekong Expedition - Phnom Penh to Ho Chi Minh

8 Day Itinerary aboard Aqua Mekong
Starts / Ends
Phnom Penh / Ho Chi Minh City
Activity Level
Variable
Admire the diverse cultures and stunning natural beauty of Cambodia & Vietnam on this 8-day small ship cruise aboard Aqua Mekong. Hikes and bike rides complement cultural tours and market visits as you explore the cities & sites of Cai Be, Chau Doc, Ho Chi Minh City, Kampong Chhnang, Kampong Tralach, Koh Chen, Phnom Penh.
  • Walk across Kampong Prasat
  • Learn more about the local products
  • Visit the Tuol Sleng Museum
  • Discover Tan Chau
Cruise Details
0
Kampong Chhnang
from $5,818
EXPLORE

Charms of the Mekong

16 Day Itinerary aboard MS Amadara
Starts / Ends
Ho Chi Minh City / Hanoi
Activities
Land & Sea Exploration
Activity Level
Variable
Embark on a 16-day cruise aboard the MS Amadara. Explore the Mekong, visit rural villages and ancient temples, and discover Angkor’s UNESCO sites in Siem Reap before concluding with an overnight stay at Ha Long Bay.
  • Explore Ho Chi Minh vibrant city
  • Visit Phnom Penh historic palaces
  • Discover Cai Be markets
  • Tour Siem Reap ancient temples
Cruise Details
0
from $5,054
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Laotian Serendipity

Vientiane to Huay Xai - 10 Day Itinerary aboard Anouvong
Starts / Ends
Vientiane / Huay Xai
Activity Level
Variable
Board the Heritage Line, Anouvong, for a 10-day cruise through the Laotian upper Mekong Delta from Vientiane to Huay Xai, Laos. Experience the local life as you cruise along the scenic Mekong River while exploring one of Southeast Asia’s most unique and charming cities.
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Luang Prabang cultural sites
  • See the crystal-water of Kuang Si
  • Explore the jungle of Ban Khok Kham
Cruise Details
0
Phnom Penh Golden Temple
from $2,741
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Mekong River - Upstream - Low water

Saigon - Siem Reap - 8 Day Itinerary aboard The Jahan
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Discover the Mekong River during low water season aboard The Jahan on this 8-day cruise, which sails along the lower Mekong from Saigon to Siem Reap. Explore the mighty Mekong and learn about the culture and history of different towns along the river.
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Tan Chau floating fish farm
  • Visit Phnom Penh cultural sites
Cruise Details
0
Floating Market in Cai Be
from $2,741
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Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard The Jahan
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Join this 8-day Mekong River cruise during the high water season from Siem Reap to Saigon. Get an inside look at the southern cultures of Vietnam and Cambodia as you travel across the mighty Mekong delta. Stop in charming port towns and immerse yourself in the city's culture and history.
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Tan Chau floating fish farm
  • Visit Phnom Penh cultural sites
Cruise Details
0
Kampong Chhnang
from $2,839
EXPLORE

Riches of the Mekong - Cruise Only

8 Day Itinerary aboard MS Amadara
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Embark on an 8-day river cruise from Siem Reap to Ho Chi Minh aboard the MS Amadara, exploring rural villages, bustling markets, and historic sites. Experience Cambodia and Vietnam’s rich culture through artisan crafts, temple visits, and unique rides by oxcart, tuk-tuk, and trishaw.
  • Explore Angkor Ban village
  • Visit Oknhatey, Silk Island
  • Tour Phnom Penh highlights
  • Discover Oudong, royal capital
Cruise Details
0
Everyday life in Vietnam
from $2,839
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Charms of the Mekong - Cruise Only

Ho Chi Minh - Siem Reap - 8 Day Itinerary aboard MS Amadara
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Embark on an 8-day river cruise aboard the MS Amadara, starting in Ho Chi Minh City, a vibrant blend of history and modernity. Cruise the Mekong River, exploring villages, pagodas, and markets and experiencing local traditions, including a monk’s blessing and artisan crafts.
  • Explore Cai Be’s vibrant workshops
  • Discover Sa Dec history
  • Visit Phnom Penh landmarks
  • Experience Oknhatey, silk weaving
Cruise Details
0
landscape view in Laos
from $4,049
EXPLORE

Laotian Serendipity

Huay Xai to Vientiane - 8 Day Itinerary aboard Anouvong
Starts / Ends
Huay Xai / Vientiane
Activities
Wildlife Viewing, Cooking Classes, Hiking, Kayaking, Spa Relaxation, Rainforest Exploration
Activity Level
Variable
Board the Heritage Line, Anouvong, for an 8-day cruise through the Laotian upper Mekong Delta from Huay Xai to Vientiane, Laos. Experience local life as you cruise along the scenic Mekong River while exploring one of Southeast Asia’s most unique and charming cities.
  • Observed locals along the river
  • Explore Luang Prabang at night
  • Visit Luang Prabang cultural sites
  • See the crystal-water of Kuang Si
  • Explore the jungle of Ban Khok Kham
Cruise Details
0
The beautiful Vinh Trang temple near My Tho
from $2,782
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Mekong River - Upstream - Low water

Saigon to Siem Reap - 8 Day Itinerary aboard Jayavarman
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Explore the Mekong River in sumptuous luxury aboard the Jayavarman on this 8-day low-water river journey, which cruises majestically along the lower Mekong from Saigon to Siem Reap. Explore the mighty Mekong and learn about the culture and history of different towns along the river.
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Tan Chau floating fish farm
  • Visit Phnom Penh cultural sites
Cruise Details
0
Sunset over the Mekong River
from $2,529
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Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard Jayavarman
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Explore the Mekong on this 8-day high-water Mekong River cruise from Siem Reap to Saigon. Get an inside look at the southern cultures of Vietnam and Cambodia as you travel across the mighty Mekong Delta. Stop in charming port towns and immerse yourself in the city's culture and history.
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Tan Chau floating fish farm
  • Visit Phnom Penh cultural sites
Cruise Details
0
Boat floating along the Mekong River
from $2,782
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Mekong River - Downstream - Low water

Siem Reap to Saigon - 8 Day Itinerary aboard Jayavarman
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Embark on this 8-day Mekong River cruise from Siem Reap to Saigon during low water season and discover the wonders of the Mekong. Experience the diverse cultures of Vietnam and Cambodia as you navigate the mighty Mekong Delta. Pause at quaint port towns and fully engage with the local culture and history.
  • Interact with locals
  • Explore Cambodian culture
  • Observed locals along the river
  • Explore the Mekong River
  • Discover villages and markets
Cruise Details
0
Flower farms in Sa Dec, Vietnam
from $2,529
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Mekong River - Upstream - High water

Saigon to Siem Reap - 8 Day Itinerary aboard Jayavarman
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Local Market Visits, Archaeological Site Visits, Village Visits
Activity Level
Variable
Embark on this 8-day high river expedition on the Jayavarman and experience the Mekong River as it flows from Saigon to Siem Reap. Explore the lower Mekong and discover the diverse cultures and historical significance of the towns along its course.
  • Explore rural villages
  • Discover skilled craftsmanship
  • Experience scenic views at Delta
  • Explore floating markets
  • Discover cultures of Mekong Delta
Cruise Details
0
Royal Palace in Phnom Penh
from $1,505
EXPLORE

Mekong River - Upstream - Low water

Phnom Penh to Siem Reap - 5 Day Itinerary aboard The Jahan
Starts / Ends
Phnom Penh / Siem Reap
Activity Level
Variable
Join this 5-day Mekong River cruise from Phnom Penh to Siem Reap. Travel across the mighty Mekong delta to get an inside look at Cambodian culture. Stop in charming port towns and immerse yourself in the city's culture and history.
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit a local home in Kampong Cham
Cruise Details
0
Royal Palace and Silver Pagoda
from $1,505
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Phnom Penh - 5 Day Itinerary aboard The Jahan
Starts / Ends
Siem Reap / Phnom Penh
Activity Level
Variable
Join this 5-day high water river cruise aboard the Jahan from Siem Reap to Phnom Penh, and travel across the mighty Mekong Delta to discover the ancient pre-Angkorian temples and Cambodian culture.
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit a local home in Kampong Cham
Cruise Details
0
The Vinh Trang Temple in My Tho, Vietnam
from $3,215
EXPLORE

From the Angkor Temples to the Mekong Delta

Siem Reap - Ho Chi Minh - 11 Day Itinerary aboard RV Indochine
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Experience an 11-day cruise on the RV Indochine from Siem Reap to Ho Chi Minh City, navigating over 2,700 miles of the Mekong River. Explore cultural landmarks like Angkor and Phnom Penh, all while enjoying colonial-inspired comfort aboard your vessel.
  • Visit the Banteay Srei temple
  • Explore the terrace of Elephants
  • Discover Kampong Chhnang
  • Tour Phnom Penh's National Museum
Cruise Details
0
Phnom Penh Royal Palace complex
from $1,243
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard The Jahan
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jahan. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.
  • Observed locals along the river
  • See the floating market in Cai Be
  • Visit Phnom Penh cultural sites
  • Visit Tan Chau floating fish farm
Cruise Details
0
Traditional mat-making
from $1,243
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard The Jahan
Starts / Ends
Phnom Penh / My Tho
Activities
Biking
Activity Level
Variable
On this 4-day journey from Phnom Penh to Saigon, cruise downstream on the lower Mekong River in majestic style aboard the Jahan. See the stunning scenery and discover the culture and history of the various towns along the mighty Mekong.
  • Experience Binh Thanh Island
  • Explore My An Hung Village
  • Discover Tan Chau
  • Experience Cao Dai
Cruise Details
0
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