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The Gate at Prasat Vimean Suor in Cambodia

Siem Reap Land & Sea Cruises

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Discover Cambodia's wonders with one of Adventure Life's 17 exceptional land and sea cruises in 2026 or 2027. Explore historic temples, bustling cityscapes, and lush countryside on land, then sail enchanting rivers. Immerse yourself in rich cultural experiences, from Khmer delicacies to traditional arts. Cambodia's beauty, from its majestic Angkor Wat to its peaceful Tonlé Sap Lake, will fascinate even the most seasoned traveler. Our cruises, lasting from 8 to 18 days, start at $3,079 and offer an unparalleled experience. Contact us to get started.
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    • Siem Reap
The Vinh Trang Temple in My Tho, Vietnam
from $3,675
EXPLORE

From the Angkor Temples to the Mekong Delta

Siem Reap - Ho Chi Minh - 11 Day Itinerary aboard RV Indochine
  • Visit the Banteay Srei temple
  • Explore the terrace of Elephants
  • Discover Kampong Chhnang
  • Tour Phnom Penh's National Museum
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Experience an 11-day cruise on the RV Indochine from Siem Reap to Ho Chi Minh City, navigating over 2,700 miles of the Mekong River. Explore cultural landmarks like Angkor and Phnom Penh, all while enjoying colonial-inspired comfort aboard your vessel.
Cruise Details
0
Killing Fields, Phnom Penh
from $7,105
EXPLORE

Luxury Mekong and Temple Discovery Cruise

Siem Reap - Ho Chi Minh - 11 Day Itinerary aboard Scenic Spirit
  • Uncover Tan Chau’s cultural gems
  • Admire Angkor Wat’s divine beauty
  • Visit Banteay Srei
  • Explore Siem Reap’s French colonial
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Wildlife Viewing
Activity Level
Variable
Experience an 11-day cruise on the Scenic Spirit through Cambodia and Vietnam, starting in Siem Reap with visits to Angkor Wat and local markets. Enjoy a Mekong River journey with stops at various towns, cultural activities, and end your trip in Ho Chi Minh City.
Cruise Details
0
Kampong Chhnang
from $6,428
EXPLORE

Charms of the Mekong

16 Day Itinerary aboard AmaDara
  • Explore Ho Chi Minh vibrant city
  • Visit Phnom Penh historic palaces
  • Discover Cai Be markets
  • Tour Siem Reap ancient temples
Starts / Ends
Ho Chi Minh City / Hanoi
Activity Level
Variable
Embark on a 16-day cruise aboard the MS Amadara. Explore the Mekong, visit rural villages and ancient temples, and discover Angkor’s UNESCO sites in Siem Reap before concluding with an overnight stay at Ha Long Bay.
Cruise Details
0
Sunset over the Mekong River
from $7,780
EXPLORE

Treasures of the Mekong

Ho Chi Minh City - Siem Reap - 13 Day Itinerary aboard Scenic Spirit
  • Explore Ho Chi Minh City’s tunnels
  • Visit Cai Be’s orchard island
  • Uncover Sa Dec’s markets
  • Admire Oudong’s serene monastery
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Cooking Classes
Activity Level
Variable
Set sail on a 13-day cruise from Ho Chi Minh City to Siem Reap aboard the Scenic Spirit, exploring the rich culture and history of Vietnam and Cambodia. Enjoy activities like cooking classes, temple tours, and immersive experiences, including a monk’s blessing and a gala dinner.
Cruise Details
0
Local moving cattle through the fields
from $6,228
EXPLORE

Riches of the Mekong

16 Day Itinerary aboard AmaDara
  • Explore Hanoi’s rich heritage
  • Cruise Ha Long’s stunning waters
  • Discover Angkor Thom’s grandeur
  • Sail Mekong’s timeless villages
Activities
Hiking
Activity Level
Variable
Embark on a 16-day cruise aboard the MS Amadara, exploring Hanoi, Ha Long Bay, Siem Reap, and Ho Chi Minh City. Discover ancient temples, cruise the Mekong River, visit charming villages, and experience the vibrant blend of history and modern life in Vietnam and Cambodia.
Cruise Details
0
Bike ride by Angkor Wat Temple
from $4,860
EXPLORE

Wonders of Cambodia, Vietnam and the Mekong

Siem Reap - Ho Chi Minh - 13 Day Itinerary aboard Emerald Harmony
  • Explore ancient Angkor Thom
  • Discover temples at Ta Prohm
  • Visit Kampong Tralach
  • Tour Vietnam’s rural life
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Embark on a 13-day cruise in Southeast Asia aboard the Emerald Harmony, exploring the ancient wonders of Angkor Wat and navigating the Mekong River. Conclude your journey with a two-night stay in Ho Chi Minh City after discovering Cambodian history and Vietnam's Cao Dai temple.
Cruise Details
0
Statues and intricate relief carvings inside Angkor Wat
from $3,874
Save 15%
EXPLORE

From the Angkor Temples to the Mekong Delta

Siem Reap to Ho Chi Minh City - 11 Day Itinerary aboard RV Indochine II
  • Visit Angkor Wat temples
  • Explore Phnom Penh landmarks
  • Visit Cu Chi tunnels in Saigon
  • Discover Koh Chen crafts
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Land & Sea Exploration, Village Visits, Archaeological Site Visits, Local Market Visits
Activity Level
Variable
Embark on an 11-day Mekong River cruise through Vietnam and Cambodia aboard RV Indochine II. Start in Siem Reap with Angkor temples, then sail across Tonle Sap Lake and explore Phnom Penh, Chau Doc, Sa Dec, Cai Be, and Ho Chi Minh City. Visit floating villages, historic landmarks, and cultural sites.
Cruise Details
0
Aerial view of Angkor Wat
from $3,340
Save 15%
EXPLORE

From the Mekong Delta to the Angkor Temples

Ho Chin Min City to Angkor - 11 Day Itinerary aboard RV Indochine
  • Visit Ho Chi Minh landmarks
  • Cu Chi tunnels tour
  • Explore Angkor Wat temples
  • Tour Sa Dec historic house
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Urban Exploration
Activity Level
Variable
Experience an 11-day Mekong River cruise from Vietnam to Cambodia aboard RV Indochine. Explore Ho Chi Minh City landmarks, My Tho canals, Phnom Penh palaces, and Siem Reap’s Angkor temples. Visit bustling markets, floating villages, craft villages, and historic sites. Discover culture, tradition, and history on a unique river adventure through Southeast Asia.
Cruise Details
0
Guest photographing Angkor Wat during Sunrise in Cambodia
from $13,556
EXPLORE

Sailing Vietnam and Cambodia’s Mekong River

Northtbound - 13 Day Itinerary aboard Jahan
  • Explore Saigon’s historic landmarks
  • Discover Phnom Penh culture
  • Witness Angkor Wat sunrise
  • Cruise Cai Be canals
  • Meet village artisans
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Embark on a 13-day Mekong River cruise through Vietnam and Cambodia, sailing aboard the elegant Jahan. Explore vibrant markets, ancient temples, floating villages, and historic landmarks from Saigon to Angkor Wat.
Cruise Details
0
A boat trip through the Tra Su Cajuput Forest in the Mekong Delta region of Vietnam
from $3,079
$2500
EXPLORE

Riches of the Mekong - Cruise Only

8 Day Itinerary aboard AmaDara
  • Explore Angkor Ban village
  • Visit Oknhatey, Silk Island
  • Tour Phnom Penh highlights
  • Discover Oudong, royal capital
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Embark on an 8-day river cruise from Siem Reap to Ho Chi Minh aboard the MS Amadara, exploring rural villages, bustling markets, and historic sites. Experience Cambodia and Vietnam’s rich culture through artisan crafts, temple visits, and unique rides by oxcart, tuk-tuk, and trishaw.
Cruise Details
0
Statues and intricate relief carvings inside Angkor Wat
from $5,010
EXPLORE

Wonders of Vietnam, Cambodia and the Mekong

Ho Chi Minh - Siem Reap - 15 Day Itinerary aboard Emerald Harmony
  • Explore Cu Chi Tunnels
  • Tour Sa Dec’s markets
  • Visit My An Hung village
  • Discover Gieng Island industries
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Experience a 15-day cruise on the Emerald Harmony through the Mekong Delta, immersing in local life in villages like My An Hung and Tan Chau. Conclude your journey in Cambodia, exploring Phnom Penh's historic sites and the iconic Angkor Wat in Siem Reap.
Cruise Details
0
Killing Fields, Phnom Penh
from $7,465
EXPLORE

Wonders of Indochina and the Mekong

Ho Chi Minh City - Bangkok - 16 Day Itinerary aboard Emerald Harmony
  • Tour Ho Chi Minh City Cu Chi Tunnel
  • Discover Ben Tre floating community
  • Visit Sa Dec bustling market
  • Wander Siem Reap wild vegetation
Starts / Ends
Ho Chi Minh City / Thailand
Activity Level
Variable
Embark on a 16-day cruise starting in Ho Chi Minh City, exploring the Mekong River and Cambodia's Phnom Penh, followed by a three-night stay in Siem Reap to visit Angkor Wat. Finally, fly to Luang Prabang, Laos, and conclude your journey in Bangkok, Thailand.
Cruise Details
0
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