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Colombia Cruises

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Sail the turquoise waters of the Caribbean on these 16 top Colombia cruises for 2027 and 2028. Discover the walled city of Cartagena, the port town of Santa Marta, and the magical Islas de San Bernardo. Some of the activities on our small ship cruises include snorkeling, hiking, and wildlife observation. Let your expert local English-speaking guides show you the hot spots and the off-the-beaten-path hidden gems in Colombia and the Caribbean coast. We work with only the best small ships that carry under 500 guests, ensuring an intimate and exclusive experience. Our Colombia cruises range from $3,150 to $43,655 for cruises of 8 to 15 days. Contact one of our trip planners for assistance to match you with the perfect cruise to Colombia.
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    • Colombia
Waterfront views and distinct Dutch colonial facades along the vibrant Handelskade in Willemstad, Curacao
from $7,965
OBC $200
EXPLORE

A Colorful Christmas Season

Curacao to Panama - 8 Day Itinerary aboard Sea Cloud Spirit
  • Explore Willemstad, Curacao
  • See colorful Dutch gabled houses
  • Visit San Felipe Fort
  • Transit the Panama Canal
Starts / Ends
Willemstad / Panama City
Activities
Small Ship Sailing, Urban Exploration
Activity Level
Variable
Set sail on an 8-day Curacao to Panama cruise aboard Sea Cloud Spirit. Explore colorful Willemstad, discover historic Cartagena, sail through the Panama Canal, and conclude in Panama City.
Cruise Details
0
Balboa
from $3,150
EXPLORE

Panama to Aruba

12 Day Itinerary aboard Star Clipper
  • Transit the Panama Canal locks
  • Walk colonial Balboa streets
  • Explore forts in Portobelo
  • Visit San Blas and Guna villages
  • See Cartagena and Santa Marta
Starts / Ends
Balboa / Oranjestad
Activity Level
Variable
Sail the Panama Canal on a 10-day Star Clippers cruise through Central America. Begin in Balboa, then transit the Panama Canal and see the locks in action. Explore Spanish forts in Portobelo, meet the Guna people in the San Blas Islands, and discover Colombia’s coastal cities of Cartagena and Santa Marta. Enjoy scenic days under sail.
Cruise Details
0
Ruins in Colon, Panama
from $6,695
Save 30%
EXPLORE

South American Explorer: Temples, Jungles & the Panama Canal

Lima to Colon - 10 Day Itinerary aboard MV Discoverer
  • Explore Ancient Peru
  • Discover Colombia's Wildlife
  • Transit Panama Canal
  • Experience Ecuador's Coast
Starts / Ends
Callao / Colon
Activities
Wildlife Viewing, Citizen Science, Photography Seminars, Whale Watching
Activity Level
Variable
Experience a 10-day expedition from Callao (Lima), Peru to Colon, Panama aboard MV Discoverer. Explore ancient archaeological sites, Ecuador’s Pacific coast, Colombia’s biodiverse rainforests, and the engineering marvel of the Panama Canal while enjoying wildlife encounters, cultural discoveries, and enriching days at sea.
Cruise Details
0
Mompox, Colombia
from $4,049
$2500
EXPLORE

Magic of Colombia - Cruise Only

Barranquilla - Cartagena - 8 Day Itinerary aboard AmaMagdalena
  • Experience Barranquilla’s Carnaval
  • Explore Sitio Nuevo’s village life
  • Discover Boca de Tacaloa landscapes
  • Stroll Mompox’s colonial streets
Starts / Ends
Cartagena / Cartagena
Activity Level
Variable
Embark on an 8-day cruise along Colombia's Magdalena River from Barranquilla to Cartagena on the AmaMagdalena. Enjoy vibrant music, local coffee, unique wildlife, and authentic cultural experiences, including a private Carnaval celebration.
Cruise Details
0
Mary in Colombia, View of Medellin from coffee plantation_
from $4,049
$2500
EXPLORE

Magic of Colombia

Barranquilla - Cartagena - 8 Day Itinerary aboard AmaMelodia
  • Experience Carnaval of Barranquilla
  • Visit Sitio Nuevo artisan crafts
  • Tour Boca de Tacaloa wetlands
  • Enjoy Mompox jazz performance
Starts / Ends
Cartagena / Cartagena
Activity Level
Variable
Experience an 8-day river cruise along Colombia's Magdalena River from Barranquilla to Cartagena on the AmaMelodia. Enjoy Carnaval festivities, explore artisan towns, and immerse yourself in local culture with music, dance, and historic tours.
Cruise Details
0
Bustling port of Fort de France, Martinique
from $6,940
EXPLORE

Panama, Colombia & Caribbean Islands

Fort-de-France - Colon - 10 Day Itinerary aboard Le Bellot
  • Uncover lush Minca
  • Stroll through Port Elizabeth
  • Admire colorful Willemstad
  • Visit historic Santa Marta
Starts / Ends
Fort de France / Colon
Activities
Snorkeling, Archaeological Site Visits, Local Market Visits, Scuba Diving, Village Visits
Activity Level
Variable
Set sail on a 10-day cruise aboard the Le Bellot to explore the stunning Caribbean, including the vibrant towns and rich history of Panama and Colombia. Swim in turquoise waters and snorkel in marine reserves while discovering unique cultures and ecosystems.
Cruise Details
0
Boats Moored to the Quay at Bridgetown Harbour
from $4,450
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Royal Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends
Bridgetown / Balboa
Activity Level
Variable
Starting at the Caribbean port of Bridgetown, this 15-day cruise aboard the Royal Clipper sails through the turquoise Caribbean waters en route to the Panama Canal, visiting Grenada, Bonaire, Curacao, Aruba, and Colombia along the way. Explore the tropical jungles, snorkel in vibrant reefs, immerse yourself in tribal culture, and marvel at the Panama Canal.
Cruise Details
0
Cartagena Old Town
from $4,049
$2500
EXPLORE

Wonders of Colombia

Cartagena - Barranquilla - 8 Day Itinerary aboard AmaMelodia
  • Experience Palenque’s rich culture
  • Celebrate Barranquilla Carnaval
  • Visit Santa Bárbara artisans
  • Ride Calamar’s historic paola
Starts / Ends
Cartagena / Cartagena
Activities
Festival Visits
Activity Level
Variable
Discover Colombia's wonders on an 8-day cruise along the Magdalena River aboard AmaMelodia. Visit Palenque, the first free city, and the vibrant Getsemaní neighborhood in Cartagena. Discover the blend of cultures, music, and art that define the country.
Cruise Details
0
Snorkeling
from $7,910
No SS
EXPLORE

Panama, Colombia & Caribbean Islands

Colon - Fort-de-France - 11 Day Itinerary aboard Le Bellot
  • Cartagena colonial old town
  • Visit Santa Marta and Sierra Nevada
  • Visit Bonaire reef marine park
  • Visit Fort-de-France landmarks
Starts / Ends
Colon / Fort de France
Activities
Hiking, Rainforest Exploration
Activity Level
Variable
Set sail on an 11-day cruise through Panaman, Colombia and Caribbean Islands aboard Le Bellot. Visit Cartagena and Santa Marta with guided historic and cultural excursions. Explore the San Blas Islands for beaches, snorkeling, and Kuna culture. The voyage combines nature, culture, and Caribbean island experiences.
Cruise Details
0
Relax on the shores of the Caribbean
from $12,295
EXPLORE

Grenadines, Colombia & Panama Canal Transit

Bridgetown - Panama City - 12 Day Itinerary aboard Emerald Azzurra
  • Explore Bequia Caribbean lifestyle
  • Admire Cartagena Old Town
  • See San Blas Islands nature
  • Navigate the Panama Canal
Starts / Ends
Bridgetown / Panama City
Activity Level
Variable
Set sail on a 12-day Caribbean cruise from Bridgetown aboard the Emerald Azzurra, exploring islands like Bequia and Mayreau. Conclude your journey in Panama City after traversing the historic Panama Canal and enjoying vibrant local cultures and stunning coastal views.
Cruise Details
0
Sunset over Cartagena, Colombia
from $12,295
EXPLORE

Panama Canal Transit, Colombia & the Grenadines

Panama City - Bridgetown - 12 Day Itinerary aboard Emerald Azzurra
  • Explore Cartagena walled Old Town
  • Discover Santa Marta oldest city
  • Tour Willemstad Queen Emma Bridge
  • See Mayreau Island Station Hill
Starts / Ends
Panama City / Bridgetown
Activity Level
Variable
Set sail on a 12-day Caribbean cruise from Bridgetown aboard the Emerald Azzurra, exploring islands like Bequia and Mayreau. Conclude your journey in Panama City after traversing the historic Panama Canal and enjoying vibrant local cultures and stunning coastal views.
Cruise Details
0
Panama's turquoise waters
from $4,450
EXPLORE

Panama to Antigua

15 Day Itinerary aboard Royal Clipper
  • Explore Balboa’s colonial charm
  • Transit Panama’s iconic canal
  • Discover San Blas culture
  • Enjoy Aruba’s clear waters
Starts / Ends
Balboa / St. John's
Activity Level
Variable
Set sail on a 15-day Royal Clipper cruise from Balboa, Panama, featuring a full Panama Canal transit and visits to the San Blas Islands, Cartagena, and the Caribbean gems of Aruba, Curacao, and Bonaire. Experience lush Grenada and volcanic St. Lucia, and finish your journey in Antigua, all while enjoying elegant sailing and stunning island views.
Cruise Details
0
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Kassandra Magruder Adventure Life employee profile
Kassandra M.
Colombia

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