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Sail the turquoise waters of the Caribbean on these 12 top Colombia cruises for 2025 and 2026. Discover the walled city of Cartagena, port town Santa Marta, and the magical Islas de San Bernardo Some of the activities on our Colombia small ship cruises include snorkeling, hiking, and wildlife observation. Let your expert local English-speaking guides show you the hot spots and the off-the-beaten-path hidden gems in Colombia and the Caribbean coast. We work with only the best small ships that carry under 500 guests, ensuring an intimate and exclusive experience. Our Colombia cruises range from $3,150 to $69,990 for cruises of 8 to 15 days. Contact one of Adventure Life's Colombia cruise specialists for assistance to match you with the perfect small cruise ship for your next vacation. 
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    • Colombia
Balboa
from $3,150
EXPLORE

Panama to Aruba

12 Day Itinerary aboard Star Clipper
  • Transit the Panama Canal locks
  • Walk colonial Balboa streets
  • Explore forts in Portobelo
  • Visit San Blas and Guna villages
  • See Cartagena and Santa Marta
Starts / Ends
Balboa / Oranjestad
Activities
Snorkeling, Small Ship Sailing, Archaeological Site Visits, Local Market Visits
Activity Level
Variable
Sail the Panama Canal on a 10-day Star Clippers cruise through Central America. Begin in Balboa, then transit the Panama Canal and see the locks in action. Explore Spanish forts in Portobelo, meet the Guna people in the San Blas Islands, and discover Colombia’s coastal cities of Cartagena and Santa Marta. Enjoy scenic days under sail.
Cruise Details
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Mompox, Colombia
from $4,039
EXPLORE

Magic of Colombia - Cruise Only

Barranquilla - Cartagena - 8 Day Itinerary aboard MS AmaMagdalena
  • Experience Barranquilla’s Carnaval
  • Explore Sitio Nuevo’s village life
  • Discover Boca de Tacaloa landscapes
  • Stroll Mompox’s colonial streets
Starts / Ends
Cartagena / Cartagena
Activity Level
Variable
Embark on an 8-day cruise along Colombia's Magdalena River from Barranquilla to Cartagena on the AmaMagdalena. Enjoy vibrant music, local coffee, unique wildlife, and authentic cultural experiences, including a private Carnaval celebration.
Cruise Details
0
Magdalena River, Colombia
from $4,039
EXPLORE

Wonders of Colombia - Cruise Only

Cartagena - Barranquilla - 8 Day Itinerary aboard MS AmaMagdalena
  • Explore vibrant Getsemani Cartagena
  • Discover historic Palenque town
  • Tour scenic Calamar by bicycle taxi
  • Witness gold artistry in Mompox
Starts / Ends
Cartagena / Cartagena
Activity Level
Variable
Sail the majestic Magdalena River on an 8-day cruise aboard the MS AmaMagdalena. Experience Colombia’s vibrant rhythms, rich history, and lively culture as you explore Palenque, Cartagena, and beyond.
Cruise Details
0
Boats Moored to the Quay at Bridgetown Harbour
from $4,450
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Royal Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends
Bridgetown / Balboa
Activity Level
Variable
Starting at the Caribbean port of Bridgetown, this 15-day cruise aboard the Royal Clipper sails through the turquoise Caribbean waters en route to the Panama Canal, visiting Grenada, Bonaire, Curacao, Aruba, and Colombia along the way. Explore the tropical jungles, snorkel in vibrant reefs, immerse yourself in tribal culture, and marvel at the Panama Canal.
Cruise Details
0
Mompox, Colombia
from $4,039
EXPLORE

Wonders of Colombia

Cartagena - Barranquilla - 8 Day Itinerary aboard MS AmaMelodia
  • Explore ancient ruins and markets
  • Visit Bocas de Cenizas and museum
  • Enjoy Columbian nature and wildlife
Starts / Ends
Cartagena / Cartagena
Activities
Festival Visits
Activity Level
Variable
Discover Colombia's wonders on an 8-day cruise along the Magdalena River aboard AmaMelodia. Visit Palenque, the first free city, and the vibrant Getsemaní neighborhood in Cartagena. Discover the blend of cultures, music, and art that define the country.
Cruise Details
0
Paradise Tropical Island - Bocas del Toro archipelago - Island Colon
from $24,990
2for1
EXPLORE

Pristine Islands of the Bahamas & the Panama Canal

Nassau - Panama City - 11 Day Itinerary aboard Scenic Eclipse
  • Explore Nassau’s colonial streets
  • Visit Staniel Cay’s beaches
  • Discover San Salvador’s coral reefs
  • Meet Cabo de La Vela’s Wayuu people
Starts / Ends
Nassau / Panama City
Activities
Wildlife Viewing, Village Visits
Activity Level
Variable
Join an 11-day cruise from Nassau to Panama City on the Scenic Eclipse, exploring the Bahamas' clear waters and vibrant island cultures. Experience highlights like Pig Beach and the Panama Canal, blending leisure with cultural discovery.
Cruise Details
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Tranquil shores and swaying palms welcome you to Cayman Brac
from $4,240
EXPLORE

Panama to Jamaica

Balboa - Montego Bay - 15 Day Itinerary aboard Star Clipper
  • Explore Balboa’s architecture
  • Transit Panama Canal’s locks
  • Discover Portobelo’s Spanish forts
  • Tour Puerto Limon’s markets
Starts / Ends
Balboa / Isla de Providencia
Activity Level
Variable
Join a 15-day cruise from Balboa to Montego Bay aboard the Star Clippers, sailing through the Panama Canal and exploring cultural gems like Portobelo and Puerto Limon. Relax at sea and visit beautiful beaches in Bocas del Toro and the diving hotspots of George Town and Cayman Brac before concluding your journey in Jamaica.
Cruise Details
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Panama's turquoise waters
from $4,450
EXPLORE

Panama to Antigua

15 Day Itinerary aboard Royal Clipper
  • Explore Balboa’s colonial charm
  • Transit Panama’s iconic canal
  • Discover San Blas culture
  • Enjoy Aruba’s clear waters
Starts / Ends
Balboa / St. John's
Activity Level
Variable
Set sail on a 15-day Royal Clipper cruise from Balboa, Panama, featuring a full Panama Canal transit and visits to the San Blas Islands, Cartagena, and the Caribbean gems of Aruba, Curacao, and Bonaire. Experience lush Grenada and volcanic St. Lucia, and finish your journey in Antigua, all while enjoying elegant sailing and stunning island views.
Cruise Details
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The vivid colors of the San Blas Islands
from $4,330
EXPLORE

Barbados to Panama

Bridgetown - Balboa - 15 Day Itinerary aboard Star Clipper
  • Explore Bridgetown’s heritage
  • Discover St. George’s coastal views
  • Admire Kralendijk’s marine life
  • Wander Willemstad’s streets
Starts / Ends
Bridgetown / Balboa
Activity Level
Variable
Set sail on a 15-day cruise with Star Clipper from Bridgetown, Barbados, exploring the Caribbean’s rich culture and history, ending in Balboa, Panama. Visit stunning destinations like Tobago Cays, Grenada, and the San Blas Islands, and experience the Panama Canal.
Cruise Details
0
Traditional Maracas in Colombia
from $4,039
$2500
EXPLORE

Magic of Colombia

Barranquilla - Cartagena - 8 Day Itinerary aboard MS AmaMelodia
  • Experience Carnaval of Barranquilla
  • Visit Nueva Venecia
  • Discover the picturesque Cienega
Starts / Ends
Cartagena / Cartagena
Activity Level
Variable
Embark on an 8-day cruise from Barranquilla to Cartagena aboard the AmaMelodia and experience the allure of Colombia. Discover the rich culture and traditions of San Agustin, Mompox, and La Dorada, and indulge in Colombia's famous coffee. Encounter the country's unique flora and fauna as you journey through this diverse and captivating land.
Cruise Details
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Sunset over Cartagena, Colombia
from $6,450
Save 20%
EXPLORE

Panama and Colombia: Exploring the Caribbean Coast

Panama to Cartagena - 8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Meet Indigenous people of Guna Yala
  • Look for unique tropical wildlife
  • See colonial architecture
Starts / Ends
Panama City / Cartagena
Activities
Kayaking, Stand Up Paddle Boarding, Hiking
Activity Level
Variable
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coasts of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Sail from Panama City to Cartagena, with stops in Portobelo, Guna Yala, Archipelago, and more.
Cruise Details
0
Mountains by the ocean in St Lucia
from $8,490
Save 10%
EXPLORE

Panama, Colombia & Caribbean Islands

Colon to Fort-de-France - 13 Day Itinerary aboard Le Champlain
  • Sail through the Central America.
  • See San Blas, Bonaire & Grenadines
  • Experience swim and snorkel.
  • Learn traditions of the Kuna people
  • Dive with an experienced instructor
Starts / Ends
Colon / Fort de France
Activities
Land & Sea Exploration
Activity Level
Variable
Join Le Bellot for an exceptional 13-day cruise sailing from Colón to Fort-de-France. This itinerary gives you the opportunity to appreciate the richness and diversity of Afro-Caribbean cultures, an azure blue sky, and white-sand beaches. Visit stunning ports, including Portobelo, Cartagena, Santa Marta, Mayreau Island, and Soufriére.
Cruise Details
0
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