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Top Czech Republic Trips & Tours in October 2025

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Discover Czech Republic in October 2025 on one of these 9 tours hand-selected by the travel experts at Adventure Life. Explore the best of during October 2025 as you enjoy Biking, Hiking, Village Visits, Local Market Visits, and Wine Tasting. Prices for trips in October 2025 range from $4,714 to $17,173 for a vacation of 10 to 22 days. Choose any of the below 9 itineraries in October 2025 and customize it when you contact one of Adventure Life's expert Czech Republic trip planners.
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    • Czech Republic
Visit charming Passau
from $7,710
2-for-1
EXPLORE

Classic Prague & Danube Delights

Prague - Budapest - 11 Day Itinerary aboard Emerald Destiny
  • Visit the Gothic St Vitus Cathedral
  • Tour the city of Regensburg
  • Explore the town of Passau
  • Ride a bike from Melk to Dürnstein
Starts / Ends
Prague / Budapest
Activity Level
Variable
Take an 11-day trip from Prague to Budapest and experience the Classic Prague and Danube Delights. Enjoy a 3-night stay and a whole day of exploration in Prague. Tour to cities like Regensburg, Passau, Melk, Vienna and more!
Cruise Details
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Budapest, the capital city of Hungary
from $5,499
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Delightful Danube & Prague

Budapest to Prague - 10 Day Itinerary aboard S.S. Beatrice
  • Explore Budapest city with a guide
  • Bike along Bavarian rivers
  • Taste Wachau Valley wines
  • Savor Viennese delicacies
Starts / Ends
Budapest / Prague
Activities
Urban Exploration
Activity Level
Variable
Sail on a 10-day cruise aboard the S.S. Beatrice along the Danube River from Budapest to Prague. Discover vibrant cities, historic castles, and cultural landmarks. Explore the architectural wonders of Budapest, Vienna, and Regensburg. Savor Viennese strudel and wine, and visit medieval castles and Jewish heritage sites.
Cruise Details
0
Enjoy a beautiful river view at sunset.
from $5,314
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Romantic Danube

11 Day Itinerary aboard MS Amasonata
  • Tour historical sites in Prague
  • See old-world architecture
  • Bike along the Inn River
  • Choose from optional excursions
Activity Level
Variable
Spend three nights in Prague and enjoy a fascinating cruise from Vilshofen to Budapest with stops in the charming cities of Passau, Austria, Vienna, and Hungary aboard the MS Amasonata.
Cruise Details
0
Gorgeous evening view of Prague
from $5,414
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Romantic Danube

Prague - Budapest - 11 Day Itinerary aboard MS Amaverde
  • Discover Prague’s medieval charm
  • Taste iconic Czech craft beers
  • Explore Passau’s historic streets
  • Stroll Regensburg’s old town
Starts / Ends
Prague / Budapest
Activity Level
Variable
Embark on an 11-day river cruise with stays in Prague aboard the MS Amaverde, exploring historic cities like Prague, Vienna, and Budapest. Experience the Danube’s charm with visits to UNESCO sites and enchanting towns like Salzburg and Cesky Krumlov.
Cruise Details
0
Gorgeous evening view of Prague
from $4,714
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Romantic Danube

11 Day Itinerary aboard MS Amabella
  • Explore Prague's historic treasures
  • Discover Regensburg medieval charm
  • Hike Passau's scenic hills
  • Marvel Vienna's imperial elegance
Starts / Ends
Prague / Budapest
Activity Level
Variable
Embark on an 11-day river cruise aboard the MS Amabella with Prague, exploring Vienna, Bratislava, and Budapest. Discover Salzburg, Cesky Krumlov, and iconic UNESCO sites along the Danube’s romantic shores.
Cruise Details
0
Panoramic view of Budapest cityscape
from $5,824
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Melodies of the Danube

Budapest - Prague - 13 Day Itinerary aboard MS Amabella
  • Discover Budapest's iconic charm
  • Explore Bratislava's regal beauty
  • Wander Vienna's historic splendor
  • Marvel at Passau’s architecture
Starts / Ends
Budapest / Prague
Activity Level
Variable
Set sail on a 13-day cruise aboard the MS Amabella and explore Prague’s wonders. Visit Prague Castle, stroll across Charles Bridge, and discover the UNESCO-listed Old Town or hike through its historic charm.
Cruise Details
0
Explore Budapest from the serene Danube
from $8,490
2-for-1
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Danube Explorer & Highlights of Budapest

Munich/Passau - Budapest - 10 Day Itinerary aboard Emerald Luna
  • Explore the Danube River
  • Visit UNESCO heritage sites
  • Explore Central Europe
  • Learn about the history of Europe
Starts / Ends
Munich / Budapest
Activities
Village Visits
Activity Level
Variable
Join this 10-day Danube Explorer & Budapest Highlights Cruise on Emerald Luna. Discover five countries and UNESCO sites, experiencing central Europe's essence. Immerse in local encounters, traditions, and cuisine. Uncover history, landmarks, and culture along the Danube's banks.
Cruise Details
0
Explore castle ruins outside beautiful Bratislava
from $9,974
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Grand Danube Cruise

Prague - Bucharest - 22 Day Itinerary aboard MS Amaverde
  • Stroll Regensburg’s medieval lanes
  • Explore Passau’s Baroque beauty
  • Discover Prague’s Gothic charm
  • Taste iconic Czech craft beers
Starts / Ends
Prague / Bucharest
Activities
Biking, Festival Visits, Hiking, Local Market Visits, Wine Tasting, Land & Sea Exploration
Activity Level
Variable
Set sail on a 22-day cruise aboard the MS Amaverde, exploring Romania, Bulgaria, Serbia, Croatia, Hungary, Austria, Germany, and the Czech Republic along the iconic Danube River. Discover historic sites like Bran Castle and the Rock-Hewn Churches of Ivanovo while immersing yourself in the region's rich culture and traditions.
Cruise Details
0
A quiet autumn morning in Bratislava
from $8,999
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Grand Danube Cruise with Prague

22 Day Itinerary aboard MS Amabella
  • Explore Prague, timeless charm
  • Cruise Regensburg, historic gem
  • Visit Salzburg, cultural treasure
  • Discover Linz, vibrant history
Starts / Ends
Prague / Bucharest
Activities
Archaeological Site Visits
Activity Level
Variable
Embark on a 22-day cruise aboard the MS Amabella, exploring Romania, Bulgaria, Serbia, and beyond through capitals like Bucharest and Prague. Cruise the Danube, uncover legends at sites like Bran Castle and the Rock-Hewn Churches of Ivanovo, and savor timeless traditions and wines.
Cruise Details
0
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