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Top Rome Cruises & Trips

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Rome
The Roman Colosseum in autumn
Italy
Trevi Fountain in Rome
Amalfi
Explore Italy's colorful Amalfi coast
Naples
Naples at Sunset, Italy
Lipari
Roman Babakin
Hiking on the Amalfi coast overlooking the Tyrrhenian sea
Ponza
Sail around the crystal waters of Corsica
Portoferraio
Charming port cities line the coves of the French Riviera
Sardinia
A small island sits out in the crystal clear waters of the sea.
Sicily
Balate Dorin
Visit charming Sicily
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Explore these 6 top Rome cruises for 2026 and 2027. Some of the most popular activities on our Rome trips include Archaeological Site Visits, Local Market Visits, Wine Tasting, Village Visits, and Biking. Discover with your expert local English-speaking guides who will show you the hot spots and the off-the-beaten-path hidden gems. We work with only the best small ships that carry under 500 fortunate guests, and we can give you unbiased advice to match you with the perfect ship and perfect cruise for your next vacation. Our Rome cruises start from $5,499 for cruises of 9 to 14 days. Contact one of Adventure Life's Rome cruise specialists for help planning a seamless trip.
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    • Rome
Piazza Navona, Rome, Italy
from $5,499
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Rome, Venice & the Jewels of Veneto

Venice to Rome - 11 Day Itinerary aboard S.S. La Venezia
  • Explore Doge’s Palace
  • Stroll Burano and Mazzorbo
  • Tour Ancient Rome
  • Visit St. Mark’s Basilica
Starts / Ends
Venice / Rome
Activities
Urban Exploration, Biking
Activity Level
Variable
Sail from Venice to Rome on an 11-day cruise aboard the S.S. La Venezia. Experience early access to St. Mark’s Basilica, Vicenza’s Teatro Olimpico, Murano’s glassblowers, and Rome’s ancient wonders. Explore Chioggia, Burano, and Padua while enjoying unforgettable cultural, historical, and culinary moments.
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Visit Rome's famed Colosseum
from $12,795
EBD
EXPLORE

The Amalfi, Sicily and Malta: The Godfather

Rome - Valletta - 12 Day Itinerary aboard MV Douglas Mawson
  • Discover Rome’s imperial relics
  • Explore Gaeta’s medieval fortress
  • Wander Naples’ ancient streets
  • Marvel at Pompeii’s ruins
Starts / Ends
Rome / Valletta
Activities
Small Ship Sailing
Activity Level
Variable
Join this 12-day cruise on the Douglas Mawson, exploring Southern Italy, Sicily, and Malta's stunning history and culture. Experience the Amalfi Coast, ancient cities, and Malta's heritage while savoring local cuisine and vibrant Mediterranean life.
Cruise Details
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Mount Etna looms over an ancient town
from $14,595
EBD
EXPLORE

The Amalfi, Sicily and Malta: The Godfather

Rome - Valletta - 13 Day Itinerary aboard MV Douglas Mawson
  • Explore Rome to view the Colosseum
  • Explore Gaeta monastery site
  • Sail the Amalfi Coast
  • Wander Agrigento and Greek ruins
Starts / Ends
Rome / Valletta
Activities
Village Visits, Archaeological Site Visits, Wine Tasting, Local Market Visits
Activity Level
Variable
Embark on a 13-day Mediterranean cruise aboard the Douglas Mawson, exploring Sicily, Malta, and the stunning Amalfi Coast. Experience ancient architecture, rich histories, and the region's famous cuisine amidst scenic coastal landscapes.
Cruise Details
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Beautiful town of Vernazza in Liguria, Italy
from $10,095
EBD
EXPLORE

Nice to Rome: La Dolce Vita

Nice - Rome - 9 Day Itinerary aboard MV Douglas Mawson
  • Stroll Nice’s Old Town
  • Discover Picasso’s creative retreat
  • Wander Saint-Paul de Vence
  • See Pisa’s Leaning Tower
Starts / Ends
Nice / Rome
Activity Level
Variable
Embark on a 9-day cruise from Nice to Rome on the Douglas Mawson, featuring guided tours, boutique shopping, and classic sites like the Colosseum. Enjoy "Your Choice" experiences, exploring iconic attractions and savoring Mediterranean culture, history, and cuisine along the way.
Cruise Details
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Evening lights of Marseille
from $13,595
EBD
EXPLORE

A Mediterranean Masterpiece

Barcelona - Rome - 13 Day Itinerary aboard MV Douglas Mawson
  • Stroll Nice’s Riviera promenades
  • Wander Port-Vendres’ streets
  • Discover Gaudí’s Sagrada Familia
  • Admire Cezanne’s landscapes
Starts / Ends
Barcelona / Rome
Activity Level
Variable
Join a 13-day cruise aboard the Douglas Mawson through Spain and Italy, starting in Barcelona with a Flamenco show and visiting landmarks like Gaudí's Sagrada Familia. Explore coastal towns and the French Riviera, and end in Rome, immersing in both countries' rich culture, art, and history.
Cruise Details
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Brilliant blue of Venice's lagoon
from $6,499
EXPLORE

Grand Highlights of Italy & Slovenia

Ljubljana to Rome - 14 Day Itinerary aboard S.S. La Venezia
  • Explore Lake Bled from Ljubljana
  • Visit Doge’s Palace
  • Tour the Vatican City
  • Taste Chioggia Wines
Starts / Ends
Ljubljana / Rome
Activity Level
Variable
Discover Slovenia and Italy on a 14-day cruise from Ljubljana to Rome aboard S.S. La Venezia. Visit Lake Bled, Venice’s Doge’s Palace, Chioggia’s markets, and the ancient wonders of Rome. Savor regional wines, explore medieval towns, and enjoy private after-hours access to St. Mark’s Basilica.
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