Have questions? We're here.
Playful sea lions

South America Cruises

Travel made your way ™
Talk with an expert
Build your ideal South America trip. Call 800.344.6118
Start Planning My Trip
Filter (558 Results)
  • Start Date
    Months
    Years
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • South America
A lovely reflection off the Amazon River
from $5,150
EXPLORE

Luxury Amazon Explorer - High Water

Roundtrip Nauta - 5 Day Itinerary aboard Aria Amazon
  • Explore the Ucayali River
  • Navigate the Zapote River
  • Tour Nauta’s local market
  • Explore the Yarapa River by skiff
Starts / Ends
Iquitos / Nauta
Activities
Local Market Visits, Fishing
Activity Level
Variable
Embark on a 5-day cruise through the Peruvian Amazon aboard the Aria Amazon, starting with a city tour in Iquitos. Experience the rich biodiversity with river excursions, rainforest hikes, and opportunities to engage with local communities, ending with a visit to the Manatee Rescue Center in Nauta.
Cruise Details
0
Snorkeling
from $7,910
No SS
EXPLORE

Panama, Colombia & Caribbean Islands

Colon - Fort-de-France - 11 Day Itinerary aboard Le Bellot
  • Cartagena colonial old town
  • Visit Santa Marta and Sierra Nevada
  • Visit Bonaire reef marine park
  • Visit Fort-de-France landmarks
Starts / Ends
Colon / Fort de France
Activities
Rainforest Exploration, Snorkeling, Scuba Diving
Activity Level
Variable
Set sail on an 11-day cruise through Panaman, Colombia and Caribbean Islands aboard Le Bellot. Visit Cartagena and Santa Marta with guided historic and cultural excursions. Explore the San Blas Islands for beaches, snorkeling, and Kuna culture. The voyage combines nature, culture, and Caribbean island experiences.
Cruise Details
0
A vast penguin colony nesting beneath the jagged, snow-dusted peaks of Salisbury Plain, South Georgia
from $19,995
EXPLORE

South Georgia In Depth Expedition Micro Cruise

Roundtrip Port Stanley - 15 Day Itinerary aboard Aureum
  • Visit the Western Falkland Islands
  • Search for wildlife and seabirds
  • Explore the Eastern Falklands
  • Discover icy South Georgia
Starts / Ends
Stanley / Stanley
Activity Level
Variable
Join a 15-day expedition cruise to South Georgia on the Explorer Yacht Aureum, where you can explore stunning landscapes and observe active wildlife, including king penguins and elephant seals. Enjoy expert photography tips while visiting historic sites like Grytviken and Fortuna Bay.
Cruise Details
0
A group of penguins on an iceburg
from $23,995
EXPLORE

Antarctica, South Georgia & the Falkland Islands

19 Day Itinerary aboard Le Lyrial
  • Learn more about Ernest Shackleton
  • Set off on Zodiac excursions
  • Explore historic, South Georgia
  • Explore Falkland Islands
Starts / Ends
Buenos Aires / Buenos Aires
Activities
Spa Relaxation
Activity Level
Variable
Board luxurious Le Lyrial on an exciting 19-day expedition cruise to Antarctica. After a flight from Buenos Aires to Ushuaia, Argentina, at the tip of South America, depart toward the Falkland Islands and South Georgia before cruising the Drake Passage and the expansive glaciers and wildlife-rich shorelines of the Antarctic peninsula.
Cruise Details
0
Rockhopper penguins
from $26,075
EXPLORE

Ultimate Antarctica: Falklands, South Georgia & the Antarctic Circle

Ushuaia Roundtrip - 24 Day Itinerary aboard Ocean Nova
  • Cruise through the Beagle Channel
  • Discover South Georgia’s glaciers
  • Visit vast king penguin colonies
  • Cross the Antarctic Circle
Starts / Ends
Port of Ushuaia / Port of Ushuaia
Activities
Kayaking, Citizen Science, Camping
Activity Level
Variable
Embark on a 24-day roundtrip cruise from Ushuaia to Antarctica, the Falkland Islands, and South Georgia aboard the Ocean Nova. Sail through the Beagle Channel, spot penguins, seals, and albatrosses in the Falklands, and explore South Georgia’s glaciers. Discover the Antarctic Peninsula’s towering icebergs and cross the Antarctic Circle.
Cruise Details
0
Cooper Bay on South Georgia Island features dramatic volcanic rock formations meeting the rough Southern Ocean
from $22,995
EXPLORE

South Georgia and Antarctica Shackleton Special Expedition Micro Cruise

Port Stanley - Ushuaia - 20 Day Itinerary aboard Aureum
  • Explore scenic Port Stanley
  • Visit historic Grytviken
  • Watch penguins in St Andrews Bay
  • Step ashore in Antarctica
Starts / Ends
Stanley / Port of Ushuaia
Activities
Hiking, Archaeological Site Visits, Photography Seminars
Activity Level
Variable
Join a 20-day cruise on the Explorer Yacht Aureum, retracing Sir Ernest Shackleton's historic survival route from South Georgia to Antarctica. Experience stunning wildlife and natural beauty while visiting significant sites like Shackleton's grave and Elephant Island.
Cruise Details
0
Relax on the shores of the Caribbean
from $12,295
EXPLORE

Grenadines, Colombia & Panama Canal Transit

Bridgetown - Panama City - 12 Day Itinerary aboard Emerald Azzurra
  • Explore Bequia Caribbean lifestyle
  • Admire Cartagena Old Town
  • See San Blas Islands nature
  • Navigate the Panama Canal
Starts / Ends
Bridgetown / Panama City
Activity Level
Variable
Set sail on a 12-day Caribbean cruise from Bridgetown aboard the Emerald Azzurra, exploring islands like Bequia and Mayreau. Conclude your journey in Panama City after traversing the historic Panama Canal and enjoying vibrant local cultures and stunning coastal views.
Cruise Details
0
Sunset over Cartagena, Colombia
from $12,295
EXPLORE

Panama Canal Transit, Colombia & the Grenadines

Panama City - Bridgetown - 12 Day Itinerary aboard Emerald Azzurra
  • Explore Cartagena walled Old Town
  • Discover Santa Marta oldest city
  • Tour Willemstad Queen Emma Bridge
  • See Mayreau Island Station Hill
Starts / Ends
Panama City / Bridgetown
Activities
Village Visits, Urban Exploration
Activity Level
Variable
Set sail on a 12-day Caribbean cruise from Bridgetown aboard the Emerald Azzurra, exploring islands like Bequia and Mayreau. Conclude your journey in Panama City after traversing the historic Panama Canal and enjoying vibrant local cultures and stunning coastal views.
Cruise Details
0
Giant lily pads on the Amazon River
from $3,856
EXPLORE

Amazon Journey via Ucayali River- Low Water Season

Iquitos to Nauta - 4 Day Itinerary aboard Zafiro
  • Visit the Mirrored Forest
  • See pink and grey dolphins play
  • Explore the black water streams
Starts / Ends
Nauta / Nauta
Activity Level
Variable
Explore the Amazon, Ucayali, and Pacaya Rivers on their way deep into the Pacaya Samiria Reserve, one of Peru´s largest national parks. Go piranha fishing, trek into the dense jungle in search of Amazon wildlife and birds, take a night safari and guided trips, visit local villages, and learn about wildlife preservation efforts in Peru’s Amazonia.
Cruise Details
0
A lone Adelie penguin on an ice floe
from $16,999
EXPLORE

Drake Fly & Sail

King George Island to Ushuaia - 11 Day Itinerary aboard World Navigator
  • Skip one Drake Passage crossing
  • Cruise the Antarctic Sound
  • Spot penguins and seals by Zodiac
  • See remote Antarctic landing sites
  • Explore Paulet Island
Starts / Ends
Punta Arenas / Buenos Aires
Activities
Wildlife Viewing, Whale Watching
Activity Level
Variable
Explore Antarctica on an 11-day cruise aboard World Navigator, starting with an overnight stay in Punta Arenas, before flying to King George Island. Skip one Drake Passage crossing and spend six days exploring the Antarctic Sound and Antarctic Peninsula. Join Zodiac excursions and shore landings to observe penguins, seals, glaciers, and icebergs.
Cruise Details
0
Enjoy a blissful snorkeling trip.
from $6,195
FreeFlight
EXPLORE

Western Islands

7 Day Itinerary aboard Treasure of Galapagos
  • Hike Dragon Hill on Santa Cruz
  • Appreciate Isabela's wetlands
  • Observe diverse wildlife
  • Snorkel, swim & hike the Galapagos
Starts / Ends
Baltra / Baltra
Activity Level
Variable
This 7-day Western Islands cruise on the ship, Treasure of the Galapagos, explores Rabida, Santa Cruz, Fernadina, and more! Experience the fascinating western islands and understand how volcanic activity and isolation shaped the landscape. Encounter diverse wildlife, birdlife, and marinelife on your memorable vacation.
Cruise Details
0
Iceberg Flow during Trip to the Antarctic Peninsula
from $19,050
EXPLORE

The Great Austral Loop

Ushuaia Roundtrip - 19 Day Itinerary aboard Le Lyrial
  • Observe New Island penguins
  • Visit South Georgia’s Gold Harbor
  • Observe whales, seals, and seabirds
  • Explore Salisbury Plain
Starts / Ends
Buenos Aires / Buenos Aires
Activity Level
Variable
Embark on a 19-day cruise from Buenos and Ushuaia to Antarctica aboard Le Lyrial. Explore the Falkland Islands, South Georgia, and the Antarctic Peninsula. Experience Zodiac landings, wildlife encounters, glaciers, and historic polar routes.
Cruise Details
0
481-492 of 558 Results

Relax. We've got this.

Talk with an expert trip planner 800.344.6118

Plan My Trip
Jason Maynard employee profile
Jason M.
Peruvian weavers
South America

Chat South America with a specialist

Our team is waiting and ready to talk with you about your next adventure. So go ahead and book an appointment with one of our specialized trip planners.

Let's Chat
800.344.6118

Where is your next adventure?

Contact Chat Call

Why Travel With Us?

Rewards That Go Further

Secure your 5% Past Traveler Rewards across a wide range of ships and destinations - not a single brand and not just cruises.

More Value.

Receive personal attention and concierge-level service for the same cost as booking direct. Gain access to exclusive rates, perks, and insider expertise on how to maximize the value for your dollar.

Advocacy That Matters

You're backed by a team that knows the industry and has strong relationships—helping ensure you're prioritized and well taken care of every step of the way.

As Featured In

How it Works

Connect

No cost, no commitment. Talk with our experts about your dream trip.

Plan

Share your travel style—we match you with the right itinerary or create one just for you.

Book

Lock in knowing every detail is handled and you’re fully supported.

Travel

Enjoy a seamless journey—and unlock 5% off your next adventure.