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South America Fly + Cruise Adventures

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Cruise South America on one of these 10 hand-picked flight and cruise combination trips by Adventure Life. Many consider combining a flight with a cruise where you normally fly one way and cruise the opposite way as the best way to see South America as they let you cover more distance in less time. Some of the most popular things to do on a fly-cruise adventure to South America are Kayaking, Whale Watching, Wildlife Viewing, Adventure Options, and Snorkeling. Prices for cruises to South America in 2025 start at $4,995 to $60,795 for voyages of 6 to 20 days. Tell us about your ideal South America experience and one of Adventure Life's travel specialists can help you design the perfect, seamless trip.
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    • South America
from $12,995
EXPLORE

Magellan Discoverer Inaugural Air-Cruise

Roundtrip Punta Arenas - 10 Day Itinerary aboard Magellan Discoverer
  • Start your adventure in Punta Arena
  • Enjoy Patagonia Adventures
  • Beagle Channel and Drake Passage
  • Antarctic Exploration
  • Return Flight from King George Isla
Starts / Ends
Punta Arenas / Punta Arenas
Activity Level
Variable
Embark on a 10-day cruise on the Magellan Discoverer from Punta Arenas to Antarctica. Sail the Strait of Magellan, explore Glacier Alley, and cross the Drake Passage to the South Shetland Islands and Antarctic Peninsula. Spend three days discovering fjords, icebergs, and wildlife before flying back from King George Island.
Cruise Details
0
from $6,795
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Antarctica Express Air Cruise

Punta Arenas - Ushuaia - 6 Day Itinerary aboard Magellan Discoverer
  • Visit the South Shetland Islands
  • Drake Passage navigation
  • Explore Puerto Williams
  • Chance to visit Cape Horn
Starts / Ends
Punta Arenas / Port of Ushuaia
Activity Level
Variable
The Antarctica Express Air cruise is a compact 6-day expedition. Begin in Punta Arenas, Chile, with a flight to King George Island to explore penguin colonies, ice-filled bays, and Antarctic wildlife. Sail through the Drake Passage, spot seabirds and whales, and, weather permitting, land at Cape Horn. Conclude in Ushuaia, Argentina.
Cruise Details
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from $17,895
25% OFF
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Antarctic Explorer - Fly/Sail Expedition

Ushuaia - Punta Arenas - 12 Day Itinerary aboard Sylvia Earle
  • See the activity of a penguin city
  • Chance to spot leopard seals
  • Cruise on a Zodiac
Starts / Ends
Punta Arenas / Ushuaia
Activities
Scuba Diving
Activity Level
Variable
Explore Antarctica on this 12-day cruise from Ushuaia to Punta Arenas aboard Sylvia Earle. Reduce your time at sea by flying one way over the Drake Passage and sailing the other way. Discover the Antarctic Peninsula, South Shetland Islands, and the Legendary Cape Horn.
Cruise Details
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A humpback whale dives beneath the Antarctic waters
from $16,195
EBD
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Antarctic Express: Sail South, Fly North

Buenos Aires - Punta Arenas - 10 Day Itinerary aboard World Voyager
  • Witness Antarctic wildlife
  • Fly over the Drake Passage
  • Visit research stations
  • Experience thrilling Zodiac rides
  • Witness massive icebergs
Starts / Ends
Port of Ushuaia / Punta Arenas
Activity Level
Variable
Embark on a 10-day Antarctic Express: Cruise South, Fly North Expedition aboard World Voyager. Antarctic cruise, exploring Ushuaia, the Drake Passage, and the Antarctic Peninsula. Encounter penguins, whales, and breathtaking ice landscapes on this once-in-a-lifetime adventure.
Cruise Details
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1800's whaling station
from $29,395
25% OFF
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South Georgia, Falklands & Antarctic Odyssey

Ushuaia - Punta Arenas - 20 Day Itinerary aboard Sylvia Earle
  • Discover South Georgia's wildlife
  • Discover Antarctica
  • Explore Antarctica's wildlife
  • Discover seals
  • Explore Falklands-Malvinas
Starts / Ends
Port of Ushuaia / Punta Arenas
Activities
Photography Seminars
Activity Level
Variable
Explore South Georgia and the Antarctic Peninsula on this 20-day cruise aboard Sylvia Earle from Ushuaia to Punta Arenas. Encounter captivating wildlife in South Georgia, learn Falklands-Malvinas' history, and witness peaceful grandeur in Antarctica, including the world's largest king penguin colonies.
Cruise Details
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Two Glacier Mountains symmetrically reflecting in the Antarctic water
from $18,695
25% OFF
EXPLORE

Antarctica: Through the Lens - Fly/Sail Expedition

12 Day Itinerary aboard Greg Mortimer
  • Fly over the Drake Passage
  • Spot penguins, seals, and whales
  • Take Zodiac cruises
  • Photograph glaciers and icebergs
Starts / Ends
Punta Arenas / Ushuaia
Activities
Snorkeling
Activity Level
Variable
Embark on the 12-day Antarctic Explorer - Fly/Sail Expedition from Punta Arenas to Ushuaia aboard the Greg Mortimer. Fly over the Drake Passage to maximize your time exploring the Antarctic Peninsula. Experience vast glaciers, penguins, seals, and whales. Take Zodiac cruises, photograph icebergs, and witness skuas.
Cruise Details
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Albatross nest amid rolling hills in Falkland Islands
from $20,395
25% OFF
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Antarctic Explorer - Fly/Sail Expedition

Punta Arenas - Ushuaia - 12 Day Itinerary aboard Douglas Mawson
  • Join a Fly/Sail cruise expedition
  • Spot Antarctic wildlife
  • Witness Antarctic Peninsula glacier
  • Watch whales in Antarctic waters
Starts / Ends
Punta Arenas / Ushuaia
Activity Level
Variable
Embark on the 12-day Antarctic Explorer - Fly/Sail Expedition from Punta Arenas to Ushuaia aboard the Douglas Mawson. Fly over the Drake Passage to maximize your time exploring the Antarctic Peninsula. Experience vast glaciers, penguins, seals, and whales. Take Zodiac cruises, photograph icebergs, and witness skuas.
Cruise Details
0
Emperor penguin chick in Antarctica
from $13,395
EBD
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Antarctic Express: Fly South, Sail North

Punta Arenas - Buenos Aires - 9 Day Itinerary aboard World Voyager
  • Fly to King George Island
  • Spot whales and penguins
  • Cross the legendary Drake
  • Experience thrilling Zodiac rides
  • Cruise the Antarctic Peninsula
Starts / Ends
Punta Arenas / Buenos Aires
Activities
Wildlife Viewing, Whale Watching, Adventure Options, Kayaking, Hiking, Stand Up Paddle Boarding, Small Ship Sailing
Activity Level
Variable
Explore the Antarctic on this 10-day Antarctic Express: Fly South, Sail North cruise from Punta Arenas to Ushuaia aboard World Voyager. Explore the breathtaking Antarctic Peninsula and the South Shetland Islands, where you'll encounter towering glaciers, massive icebergs, and diverse wildlife, including penguins, whales, and seals.
Cruise Details
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Air transportation
from $5,995
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Antarctica Express Air Cruise

Ushuaia - Punta Arenas - 6 Day Itinerary aboard Magellan Explorer
  • Visit the legendary Cape Horn
  • Attend presentations and lectures
  • Sail through ice-filled bays
  • Explore Antarctic bases & stations
Starts / Ends
Port of Ushuaia / Punta Arenas
Activity Level
Variable
The shortest possible trip to Antarctica is this 6-day cruise/flight starting in Ushuaia, through the Beagle Channel, legendary Cape Horn, and mythical waters of the Drake Passage to experience a day in one of the most spectacular places on earth - Antarctica! Return on a flight from King George Island to Patagonia's Punta Arenas, Chile.
Cruise Details
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Incredible ice formations
from $4,995
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Antarctica Express Air Cruise

6 Day Itinerary aboard Ocean Nova
  • Visit the legendary Cape Horn
  • Attend presentations and lectures
  • Sail through ice-filled bays
  • Explore Antarctic bases & stations
Starts / Ends
Port of Ushuaia / Punta Arenas
Activity Level
Variable
The fastest possible trip to Antarctica, and one of most economical is this 6-day cruise/flight starting in Ushuaia. Sail the Beagle Channel, Cape Horn, and mythical Drake Passage to experience a day in one of the most spectacular places on earth - Antarctica! Return on a flight from King George Island to Patagonia's Punta Arenas, Chile.
Cruise Details
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