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South America Fly + Cruise Adventures

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Cruise South America on one of these 13 flight and cruise combination trips selected by Adventure Life. These trips usually include a flight one way and a cruise the other way, which is a good option if you want to see more of South America in less time. Popular activities on these fly-cruise trips include Wildlife Viewing, Kayaking, Whale Watching, Photography Seminars, and Hiking.Trips to South America in 2026 start at $11,900 to $100,625 for 9 to 25 days-day itineraries. Let us know what kind of experience you're looking for in South America, and an Adventure Life travel specialist can help you plan the right trip.
 
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    • South America
from $11,900
EXPLORE

Galapagos Inner Loop

San Cristobal to San Cristobal - 10 Day Itinerary aboard Silver Origin
  • Observe Galapagos Wildlife
  • Visit Historic Post Office
  • Explore Volcanic Islands
  • Discover Conservation Efforts
Starts / Ends
San Cristobal / San Cristobal Airport
Activity Level
Variable
Discover the Galapagos on this 10-day journey from San Cristobal to San Cristobal aboard Silver Origin. Begin with a two-night stay in Quito before exploring islands including Bartolome, Isabela, Fernandina, Floreana, and Santa Cruz. Observe wildlife, snorkel, kayak, hike volcanic landscapes, and visit conservation centers.
Cruise Details
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Iconic wildlife of the Galapagos sunning themselves
from $12,600
EXPLORE

Galapagos Outer Loop

San Cristobal to San Cristobal - 10 Day Itinerary aboard Silver Origin
  • Explore Quito Ecuador pre-cruise
  • Experience Genovesa Island
  • Observe North Seymour wildlife
  • Discover Española cliff ecosystems
Starts / Ends
Quito / Quito
Activity Level
Variable
Experience a 10-day journey from Quito, Ecuador to San Cristóbal, Galápagos aboard Silver Origin with pre-cruise stays in Quito, volcanic islands, and guided wildlife encounters across Genovesa, Española, Fernandina, and Santa Cruz, featuring snorkeling, hiking, and iconic species.
Cruise Details
0
from $12,995
EXPLORE

Magellan Discoverer Inaugural Air-Cruise

Roundtrip Punta Arenas - 10 Day Itinerary aboard Magellan Discoverer
  • Start your adventure in Punta Arena
  • Enjoy Patagonia Adventures
  • Beagle Channel and Drake Passage
  • Antarctic Exploration
  • Return Flight from King George Isla
Starts / Ends
Punta Arenas / Punta Arenas
Activity Level
Variable
Embark on a 10-day cruise on the Magellan Discoverer from Punta Arenas to Antarctica. Sail the Strait of Magellan, explore Glacier Alley, and cross the Drake Passage to the South Shetland Islands and Antarctic Peninsula. Spend three days discovering fjords, icebergs, and wildlife before flying back from King George Island.
Cruise Details
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Penguin jump in Antarctica
from $13,495
Save 15%
EXPLORE

Complete Antarctica: Sail In, Fly Out

Ushuaia - Punta Arenas - 11 Day Itinerary aboard Ocean Nova
  • Cross Drake Passage route
  • Explore Antarctic Peninsula landing
  • Visit South Shetland Islands
  • Explore Estancia Olga Teresa
Starts / Ends
Ushuaia / Punta Arenas
Activity Level
Variable
Take an 11-day trip from Ushuaia, Argentina to Punta Arenas, Chile aboard Ocean Nova. Cross the Drake Passage, explore Antarctica by Zodiac, and visit the South Shetland Islands and King George Island. Observe penguins, seals, and whales, and learn from onboard experts during the journey.
Cruise Details
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Mirror-smooth waters in the Lemaire Channel
from $19,400
EXPLORE

King George Island to King George Island

Antarctica Bridge - 10 Day Itinerary aboard Silver Endeavour
  • Explore the Antarctic Peninsula
  • Fly straight to Antarctica
  • Discover King George Island
  • Observe Adelie Penguins
Starts / Ends
Santiago / Puerto Williams
Activity Level
Variable
Sail on a 10-day fly-cruise aboard Silver Endeavour, flying to King George Island to begin an Antarctic expedition. Explore the Antarctic Sound, Antarctic Peninsula, and South Shetland Islands through guided Zodiac cruises, landings, and wildlife encounters.
Cruise Details
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Penguins on the shores of Antarctica
from $33,195
EBD
EXPLORE

South Georgia, Falklands & Antarctic Odyssey

Ushuaia - Punta Arenas - 20 Day Itinerary aboard Sylvia Earle
  • Discover Falklands’ beaches
  • Marvel at South Georgia’s glaciers
  • Spot Antarctica's wildlife
  • Explore Ushuaia’s rugged landscapes
Starts / Ends
Port of Ushuaia / Punta Arenas
Activities
Snorkeling
Activity Level
Variable
Join a 20-day cruise on the Sylvia Earle, exploring Ushuaia, the Falklands, South Georgia, and Antarctica. Experience stunning landscapes, diverse wildlife, and expert-led activities, concluding with a flight from King George Island to Punta Arenas.
Cruise Details
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1800's whaling station
from $32,295
EBD
EXPLORE

South Georgia, Falklands & Antarctic Odyssey

Ushuaia - Punta Arenas - 20 Day Itinerary aboard Sylvia Earle
  • Discover Falklands’ beaches
  • Marvel at South Georgia’s glaciers
  • Spot Antarctica's wildlife
  • Explore Ushuaia’s rugged landscapes
Starts / Ends
Port of Ushuaia / Punta Arenas
Activities
Scuba Diving
Activity Level
Variable
Join a 20-day cruise on the Sylvia Earle, exploring Ushuaia, the Falklands, South Georgia, and Antarctica. Experience stunning landscapes, diverse wildlife, and expert-led activities, concluding with a flight from King George Island to Punta Arenas.
Cruise Details
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Blue ice of Antarctica
from $13,495
Save 15%
EXPLORE

Antarctica: Fly the Drake Passage

Punta Arenas Roundtrip - 9 Day Itinerary aboard Ocean Nova
  • Observe South Shetland Islands
  • Visit Chilean Patagonia ranch
  • Explore King George Island
  • View Antarctic wildlife encounter
Starts / Ends
Punta Arenas / Punta Arenas
Activity Level
Variable
9-day expedition from Punta Arenas aboard Ocean Nova. Journey includes flight to King George Island, Antarctic Peninsula exploration via Zodiac and shore landings, visits to the South Shetland Islands, and a return via Punta Arenas with a Patagonia excursion before departure.
Cruise Details
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An ocean of icebergs.
from $19,995
EXPLORE

Antarctica & South Georgia Air-Cruise

Ushuaia - Punta Arenas - 18 Day Itinerary aboard Magellan Discoverer
  • Visit historic Grytviken
  • Witness king penguin colonies
  • Explore Antarctic Peninsula
  • Trace Shackleton’s expedition
Starts / Ends
Port of Ushuaia / Punta Arenas
Activities
Hiking
Activity Level
Variable
Explore South Georgia and Antarctica on this 18-day expedition from Ushuaia to Punta Arenas aboard Magellan Discoverer. Visit Grytviken, St. Andrew’s Bay, Salisbury Plain, Elephant Island, the South Shetland Islands, and the Antarctic Peninsula. Travel by Zodiac, attend expert talks, and observe penguins, albatrosses, glaciers, and historic sites.
Cruise Details
0
An ocean of icebergs.
from $13,495
Save 15%
EXPLORE

Complete Antarctica: Fly In, Sail Out

Punta Arenas - Ushuaia - 9 Day Itinerary aboard Ocean Nova
  • Cross Drake Passage flight
  • Explore Antarctic Peninsula sites
  • Observe penguins seals whales
  • Tour South Shetland Islands
Starts / Ends
Punta Arenas / Ushuaia
Activities
Wildlife Viewing, Kayaking, Whale Watching, Photography Seminars, Citizen Science
Activity Level
Variable
Travel 9 days from Punta Arenas, Chile to Ushuaia, Argentina aboard Ocean Nova. Fly across the Drake Passage, explore Antarctica and the South Shetland Islands, and observe penguins, seals, and whales. Take part in guided landings, Zodiac excursions, and educational sessions with polar experts.
Cruise Details
0
Mirror-smooth waters in the Lemaire Channel
from $45,980
Savings
EXPLORE

Antarctica, South Georgia and the Falklands

Roundtrip Buenos Aires - 22 Day Itinerary aboard National Geographic Endurance
  • Admite Antarctica's unique beauty
  • Observe spectacular wildlife
  • Discover three different regions
  • Enjoy incredible photo ops
Starts / Ends
Buenos Aires / Santiago
Activity Level
Variable
This extraordinary 22-day Antarctica expedition takes you to Antarctica, South Georgia, and the Falkland Islands. Enjoy an extra day at the Peninsula by flying from the Falkland Islands back to the mainland. Take full advantage of rare wildlife sightings, watching whales feed off the bow or perfect conditions for a late day kayaking excursion.
Cruise Details
0
Spot king penguins in subantarctic islands
from $37,274
HALF DEP
EXPLORE

Antarctica, South Georgia, and the Falklands

Roundtrip Santiago, Chile - 22 Day Itinerary aboard National Geographic Resolution
  • Marvel at a king penguin colony
  • Experience Antarctic ice
  • See incredible wildlife
  • Travel to three distinct regions
Starts / Ends
Santiago / Santiago
Activity Level
Variable
Marvel at vast colonies of penguins, spot majestic whales, look for a variety of species of seals, and watch soaring sea birds. Explore rugged, untouched landscapes, and be humbled by massive icebergs and mountains. The ultimate Southern Ocean experience, this unforgettable 22-day expedition cruise takes you into spectacular wilderness.
Cruise Details
0
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Peruvian weavers
South America

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