Top South America Tours & Cruises in 2027

Embark on this 4-day Amazon River luxury cruise on the Aqua Nera, from the Amazon port town of Iquitos. Your journey includes Yacapana Islands, Lake Clavero, Pacaya Samiria National Reserve, and the major tributaries of Ucayali and Maranon. Keep your eyes open for the mysterious pink river dolphin along the way, and enjoy activities like hiking & kayaking.

On this 5-day Casanare Wildlife Safari in Colombia, witness incredible wildlife in El Encanto de Guanapalo natural reserve. You explore a vast plain with extensive ranches that still preserve the traditions of the region, experiencing these customs with Llaneros while riding horses through the savannahs.

On this 7-day Coastal Gems of Uruguay Tour, discover José Ignacio, like the Hamptons for New Yorkers, which offers a chic getaway with a relaxed, sophisticated vibe and a unique South American bohemian charm. Visit Rocha Province, part of UNESCO's Bañados del Este Biosphere Reserve, which boasts exceptional biodiversity.

Explore in 5 days Galapagos Islands and navigate on Fragata yacht around Santa Cruz, Isabela and Rabida islands

The Sacred Valley and Lares Adventure to Machu Picchu offers the perfect combination of traditional adventure travel and cultural immersion. This 8-day lodge-to-lodge journey will alternate between an exploration of the astounding natural scenery of the Sacred Valley and an intimate look at Andean culture, both in busy towns and in remote of mountain hamlets.

Designed for the active traveler, this 5-day tour based at Araras EcoLodge in Brazil enables you to walk, trek, horseback ride, canoe, and bike around the expansive Pantanal region. Enjoy a new adventure every day as you marvel at the unique flora, fauna, and landscape, accompanied by an expert local guide.

One of the most remote, authentic, and adventurous Amazon tours! Travel by kayak deep into the Ecuadorian Amazon jungle looking for tapir, monkeys, macaws, and other wildlife.

On this 4-day Uruguay Beach Escape Tour, discover José Ignacio, Uruguay's equivalent of the Hamptons for locals, where you can escape the urban hustle in style. This small coastal town radiates a unique South American bohemian allure that's simply enchanting. Make sure to secure reservations for all the essential local experiences!

Explore the Amazon rainforest, one of the most biodiverse regions in the world, while staying at an eco-lodge like Calanoa Amazonas during this 5-day Calanoa Amazonas Experience in Colombia. Learn about conservation efforts to preserve wildlife while viewing exotic species and their natural habitats.

Experience the iconic wilderness of Patagonia’s saw-toothed peaks, cerulean glaciers, and soaring fjords over 10 days of exploration. Discover Chilean Patagonia’s highlights including the stunning Beagle Channel and famous Cape Horn. Hike, kayak, and Zodiac cruise wild fjords, and explore wildlife reserves not easily accessible to the public.

Begin and end your nine-day trip discovering the best of Ecuador high in the Andes where we'll explore the colonial capital city of Quito. Then, bargain with colorfully-dressed indigenous women in the Otavalo Market, visit the Bellavista Cloud Forest, Cotopaxi Volcano & National Park and the town of Baños on this tour of the best of the Ecuadorian Andes.

Spend four nights in the Ecuadorian Amazon at the La Selva rainforest lodge with professional naturalists and indigenous guides. Paddle a canoe on black water lakes, spot monkeys and birds in the rainforest canopy, and relax away the evenings on one of the most luxurious experiences in the Amazon Rainforest.