Have questions? We're here.
What a view.

Top South America Tours & Cruises in 2028

Travel made your way
Talk with an expert
Build your ideal South America trip. Call 1.406.541.2677
Start Planning My Trip
Filter (204 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • South America
Sea lions bask in the sun on the beach
from $8,339
EXPLORE

Galápagos Islands Expedition Cruise – In Darwin’s Footsteps

Quito Roundtrip - 9 Day Itinerary aboard Santa Cruz II
  • Visit Cerro Colorado
  • Observe friendly sea lions
  • Admire South Plaza's natural beauty
  • Snorkel & kayak at Gardner Bay
Starts / Ends
Quito / Baltra
Activities
Urban Exploration
Activity Level
Variable
Join the Santa Cruz II on a fantastic 9-day sailing adventure exploring the wonderful Galapagos Islands. This famous volcanic archipelago is considered one of the world's foremost destinations for wildlife viewing. Visit Baltra, Isabela, Fernandina, Santa Cruz, and Floreana.
Cruise Details
0
Green sea turtle swimming
from $8,195
EXPLORE

Southern Islands

San Cristobal - Baltra - 4 Day Itinerary aboard Hermes Ultra Luxury Cruise
  • Visit Tijeretas Hill bird colony
  • Discover Floreana Island's beaches
  • Snorkel with sea lions
Starts / Ends
San Cristobal Airport / Baltra
Activities
Stand Up Paddle Boarding
Activity Level
Variable
Set sail on a 4-day Hermes Ultra Luxury Cruise to the Eastern Galapagos Islands. Explore San Cristóbal, and visit Tijeretas Hill. Enjoy Gardner Bay and Punta Suárez on Española, then discover unique beaches, flamingos, and marine life at Punta Cormorant on Floreana. Conclude your journey at the Charles Darwin Research Station and fly back home.
Cruise Details
0
A monkey in the Amazon
from $4,250
Up to 30%
EXPLORE

Luxury Amazon Discovery - Low Water

Roundtrip Nauta - 4 Day Itinerary aboard Aria Amazon
  • Explore Iquitos heritage charm
  • Experience the Marañon River
  • Spot Amazon wildlife
  • Visit Yarapa River villages
Starts / Ends
Iquitos / Nauta
Activities
Rainforest Exploration, Fishing
Activity Level
Variable
Experience a 4-day Amazon River cruise on the Aria Amazon, starting with a city tour and tasty Amazon-inspired cuisine. Explore vibrant wildlife along the Ucayali, Tahuayo, and Yarapa Rivers, while enjoying nighttime excursions and a visit to local villages.
Cruise Details
0
Christ the Redeemer Statue in Rio de Janeiro
from $1,001
EXPLORE

Highlights of Rio

4 Day Itinerary
  • Visit Christ the Redeemer
  • Enjoy views from Sugarloaf Mountain
  • Tour Rio de Janeiro's city center
Activity Level
Relaxed
This 4-day exploration of Rio de Janeiro highlights all the main attractions, including visits to Christ the Redeemer, Corcovado, and Sugarloaf Mountain. Customize this tour to suit your needs and explore the marvelous city at your own pace, from its lively clubs to its marvelous cathedrals. It makes a perfect extension to any other Brazil trip!
Tour Details
0
Blue-footed Booby lands on North Seymour Island, Galapagos Islands.
from $7,300
HALF DEP
EXPLORE

Exploring Galapagos

Quito Roundtrip - 10 Day Itinerary aboard National Geographic Endeavour II
  • View endemic wildlife
  • Discover scenic coastlines
  • See varied islands and habitats
  • Experience the Galápagos undersea
Starts / Ends
Quito / Quito
Activities
Whale Watching
Activity Level
Variable
Spend 10 days exploring the legendary Galapagos Islands aboard National Geographic Endeavour II. Actively experience the wildlife and wonders of the islands through kayaking, snorkeling, swimming, and hiking.
Cruise Details
0
A pair of friendly sea lions
from $13,207
EXPLORE

Galapagos Islands – In Darwin’s Footsteps plus Machu Picchu

Lima to Quito - 14 Day Itinerary aboard Santa Cruz II
  • Discover Machu Picchu
  • Travel Charles Darwin's footsteps
  • Cruise Galapagos Islands
  • Discover wildlife on land and sea
Starts / Ends
Lima / Quito
Activities
Wildlife Viewing, Archaeological Site Visits, Snorkeling, Kayaking, Hiking, Land & Sea Exploration, Local Market Visits, Biking, Citizen Science
Activity Level
Variable
Travel from Lima, Peru, to the Galapagos and Quito on this 14-day adventure aboard Santa Cruz II. You explore Machu Picchu, Cusco, and the Sacred Valley before cruising the Galapagos Islands and encountering iconic wildlife.
Cruise Details
0
Bartolome Island and Pinnacle Rock
from $9,993
EXPLORE

Galapagos Islands – Nine of the Best Isles

Quito Roundtrip - 11 Day Itinerary aboard Santa Cruz II
  • Explore Quito Old Town
  • See nine of the best isles
  • Discover Isabela & Fernandina
  • Experience Santiago coastline
  • Learn islands and Darwin research
Starts / Ends
Quito / Baltra
Activity Level
Variable
Enjoy an 11-day Galapagos Island Cruise on Santa Cruz II, starting in Quito and visiting Santa Cruz, Isabela, Fernandina, and more. Discover wildlife, beaches, and volcanic landscapes.
Cruise Details
0
Sacha Lodge La Balsa Restaurant
from $2,896
EXPLORE

Sacha Lodge

Ecuadorian Amazon - 7 Day Itinerary
  • Paddle dugout canoes along creeks
  • Take night walks through the forest
  • Observe the unique wildlife
  • View the forest from the canopy
Activities
Wilderness Lodge Exploration
Activity Level
Easy Active
Flying from Quito to the Amazonian city of Coca, board a canoe down the Napo River where we'll have four nights exploring the Amazon rainforest at Sacha Lodge. Luxury accommodations, gourmet cuisine, English-speaking naturalists & indigenous guides revealing monkeys, birds & Amazonian wildlife will make your weeklong trip to Ecuador unforgettable.
Tour Details
0
Puntiagudo Volcano, a snow-cappedd volcanic chain in Chile, near Osorno Volcano
from $2,650
EXPLORE

Chile's Three Lakes & Volcanoes Crossing

Chile Small Group Tour - 4 Day Itinerary
  • Hike the Desolacion Trail
  • Boat ride to Puntiagudo Valley
  • Hike to Lake Rupanco
  • Visit hot springs by Lake Rupanco
Starts / Ends
Puerto Varas / Puerto Varas
Activities
Village Visits, Homestays
Activity Level
Moderate
Join a 4-day trek in Chile's Lake District, connecting three lakes and volcanoes. Hike the Desolación Trail to Lake Todos Los Santos, take a boat to Puntiagudo Valley, and trek 8.5 km to a family lodge. On day three, hike 18 km to Lake Rupanco for stunning views. End with a soak in natural hot springs before returning to Puerto Varas.
Tour Details
0
Cotopaxi volcano in Ecuador
from $2,234
EXPLORE

Ecuador North to South

8 Day Itinerary
  • Hike on Cotopaxi Volcano
  • Take a train over Naríz del Diablo
  • Explore the ruins of Ingapirca
  • Visit a unique mangrove forest
Activities
Hacienda Visits
Activity Level
Relaxed
This tour of Ecuador offers visitors some of the most stunning natural beauty and cultural diversity on the continent. Wander the cobblestone streets of colonial Quito, experience indigenous cultures near Cotopaxi and Quilotoa volcanoes, ride the panoramic Nariz del Diablo train, explore Inca ruins and colonial Cuenca before finishing our trip in Guayaquil.
Tour Details
0
Sunset over Salar de Uyuni
from $1,310
EXPLORE

La Paz and Uyuni

4 Day Itinerary
  • See giant cacti up to 32-ft tall
  • Explore La Paz with your guide
  • Visit Uynui Salt Flats
Starts / Ends
La Paz / La Paz
Activity Level
Easy Active
On this 4-day tour, you will get a taste of Bolivia's geographical diversity from volcanos to ancient salt flats. Visit the capital city of La Paz, where you can wander through the colorful markets and marvel at the historic architecture before flying to Uyuni to explore the famous region of the world's largest salt flats, visible from space.
Tour Details
0
from $15,800
EXPLORE

Galapagos Inner Loop

San Cristobal to San Cristobal - 10 Day Itinerary aboard Silver Origin
  • Observe Galapagos Wildlife
  • Visit Historic Post Office
  • Explore Volcanic Islands
  • Discover Conservation Efforts
Starts / Ends
San Cristobal / San Cristobal Airport
Activity Level
Variable
Discover the Galapagos on this 10-day journey from San Cristobal to San Cristobal aboard Silver Origin. Begin with a two-night stay in Quito before exploring islands including Bartolome, Isabela, Fernandina, Floreana, and Santa Cruz. Observe wildlife, snorkel, kayak, hike volcanic landscapes, and visit conservation centers.
Cruise Details
0
25-36 of 204 Results

Relax. We've got this.

Talk with an expert trip planner 1.800.344.6118

Plan My Trip
Franny Friesz Adventure Life employee profile
Franny F.
Peruvian weavers
South America

Chat South America with a specialist

Our team is waiting and ready to talk with you about your next adventure. So go ahead and book an appointment with one of our specialized trip planners.

Let's Chat
1.800.344.6118

Where is your next adventure?

Contact Chat Call

Why Travel With Us?

Rewards That Go Further

Secure your 5% Past Traveler Rewards across a wide range of ships and destinations - not a single brand and not just cruises.

Unbiased Cruise Expertise

We're not tied to any one cruise line, so you receive honest guidance on the best ship and itinerary for you—not a sales pitch.

Expert Guidance

With deep destination expertise in complex travel, we advise on how to maximize your time, avoid common pitfalls, and get the most out of every part of your trip.

As Featured In

How it Works

Connect

No cost, no commitment. Talk with our experts about your dream trip.

Plan

Share your travel style—we match you with the right itinerary or create one just for you.

Book

Lock in knowing every detail is handled and you’re fully supported.

Travel

Enjoy a seamless journey—and unlock 5% off your next adventure.