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Top Spain Trips & Tours in May 2025

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Discover Spain in May 2025 on one of these 19 tours hand-selected by the travel experts at Adventure Life. Explore the best of Pinhão, Regua, Porto, Vega de Terron, and Salamanca during May 2025 as you enjoy cruises, wine tasting, river cruises, food & wine, and luxury. Prices for trips in May 2025 range from $1,430 to $28,690 for a vacation of 7 to 15 days. Choose any of the below 19 itineraries in May 2025 and customize it when you contact one of Adventure Life's expert Spain trip planners.
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Porto Cityscape, Portugal
$3,939
EXPLORE

Flavors of Portugal & Spain - Cruise Only

Porto - Vega de Terron - 8 Day Itinerary aboard MS Amavida
  • Explore Porto's historic old town
  • Taste Portugal's wines
  • Visit Nossa Senhora dos Remédios
  • Hike through Vega Terron, Spain
Activities:
Hiking, Small Ship Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
Embark on an 8-day cruise aboard the MS Amavida from Porto, the enchanting "City of Bridges" and gateway to the picturesque Douro River Valley, a UNESCO World Heritage Site renowned for its terraced vineyards and charming quintas perched along the steep riverbanks. Delight in wine …
Cruise Details
0
Porto with Dom Luis Bridge
$4,929
EXPLORE

Enticing Douro

11 Day Itinerary aboard MS Amadouro
  • Tour Belem Tower
  • Explore the Castelo da Pena
  • Travel to Lamego
  • Enjoy Sandeman Winery
Starts / Ends:
Lisbon / Regua
Activities:
Hiking, Land & Sea Exploration, River Cruises, Wine Tasting
Activity Level:
Variable
Rambling vineyards and charming native farms cling to the steep sides of the Douro River Valley, creating an incomparable backdrop to one of Europe’s most unspoiled regions and to Port country — the world’s oldest demarcated wine region. Visit Porto, the beautiful “City of …
Cruise Details
0
Explore historic Porto
$10,190
2-for-1
EXPLORE

Delightful Douro

Porto Roundtrip - 8 Day Itinerary aboard Scenic Azure
  • Explore the Douro Museum in Regua
  • Enjoy the elegant town of Lamego
  • Visit Salamanca
  • Be amazed by the Côa Valley Museum
Starts / Ends:
Porto / Porto
Activities:
Local Market Visits, River Cruises, Village Visits
Activity Level:
Variable
From windswept seaside meanderings to the astonishing beauty of the Douro Valley, this is a journey of contemplation and elegance. In Porto, board the luxurious Scenic Azure, which will transport through the hidden gems of the Douro Valley. Days will be spent immersed in the proud history and …
Cruise Details
0
Portuguese city on the river
$5,919
EXPLORE

Flavors of Portugal & Spain

Lisbon - Madrid - 14 Day Itinerary aboard MS Amavida
  • Explore Lisbon's vibrant charm
  • Discover Belem Tower's rich history
  • Cruise Porto's scenic Douro River
  • Visit Sintra's fairytale palace
Starts / Ends:
Lisbon / Madrid
Activities:
Hiking, Land & Sea Exploration, Village Visits, Wine Tasting
Activity Level:
Variable
Embark on a 14-day cruise with stays in Lisbon and Madrid aboard the MS Amavida. Begin your journey in vibrant Lisbon and conclude in dynamic Madrid, exploring the rich heritage of Portugal and Spain. Lisbon dazzles with Old World architecture and tales of legendary explorers, while nearby Sintra …
Cruise Details
0
Admire sun-soaked Malaga
$1,880
EXPLORE

Grand Prix Trials

7 Day Itinerary aboard Royal Clipper
  • Explore Malaga
  • Discover Granada
  • Experience Ibiza
  • Visit Mahon
Starts / Ends:
Malaga / Cannes
Activities:
Small Ship Cruises, Small Ship Sailing
Activity Level:
Variable
Embark on a 7-day cruise aboard the Royal Clipper through the stunning destinations of Malaga, Ibiza, Mahon, Fontvieille, and Cannes. In Malaga, marvel at the magnificent Moorish architecture of the Alcazaba and Castillo de Gibralfaro. Granada awaits with the breathtaking Alhambra Palace, a …
Cruise Details
0
Porto Cityscape, Portugal
$5,499
EXPLORE

Douro River Valley

Roundtrip Porto - 8 Day Itinerary aboard S.S. Sao Gabriel
  • Wander Salamanca's ancient streets
  • Tour Braga's rich history
  • Visit Douro Museum
  • Tour Porto’s Ribeira
Starts / Ends:
Porto / Porto
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Wine Tasting
Activity Level:
Variable
Embark on an 8-day cruise to and from Porto aboard the S.S. Sao Gabriel. Along the Douro River, cruising past Portugal's terraced hills, charming villages, and vineyards. Enjoy exclusive Port tastings, explore Porto's historic Ribeira district, and visit the UNESCO-listed Douro Valley. …
Cruise Details
0
Sprawling vineyards of France
$6,814
EXPLORE

Colors of Provence

14 Day Itinerary aboard MS Amakristina
  • Enjoy Lyon's culinary delights
  • Visit the Beaujolais wine region
  • Join a Provencal cooking lesson
  • Admire Antoni Gaudi’s works
Starts / Ends:
Paris / Barcelona
Activities:
Archaeological Site Visits, Biking, Cooking Classes, River Cruises, Urban Exploration, Wine Tasting
Activity Level:
Variable
Cruise through France’s legendary wine growing regions, home to such famous vintages as Beaujolais and Côte du Rhône. Enjoy wine tastings at local vintners, marvel at ancient Roman ruins, stroll through medieval villages, and shop for Provencal crafts. Visit the UNESCO World …
Cruise Details
0
Waterways of Libourne
$5,639
EXPLORE

Taste of Bordeaux

15 Day Itinerary aboard MS Amadolce
  • Visit the Atrium
  • Tour Arcachon
  • Explore the Castle of Roquetaillade
  • Enjoy wine tasting
Activities:
Land & Sea Exploration, Wine Tasting
Activity Level:
Variable
Board the Amadolce and enjoy 2 nights in Bilbao and 2 nights in San Sebastian leading up to a 7-night roundtrip Bordeaux cruise, followed by 2 nights in the Loire Valley and 1 night in Paris. On your roundtrip Bordeaux cruise enjoy one of the world’s undisputed wine regions. Iconic …
Cruise Details
0
Visit the historic Belem tower near Lisbon
$9,015
2-for-1
EXPLORE

Secrets of the Douro & Lisbon

Porto - Lisbon - 11 Day Itinerary aboard Emerald Radiance
  • Visit Ruins of Lisbon
  • Experience Roman times.
  • Explore Douro Valley
  • Amaze with eclecticmix architecture
Starts / Ends:
Pinhão / Lisbon
Activities:
Archaeological Site Visits, River Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
Start your journey in the Portuguese capital of Lisbon, where the cobbled alleyways and ancient ruins are yours to explore before meeting your Emerald Waterways Star-Ship in Porto. A symbol of Portugal’s birth and growth as a nation, the Douro has long been the country’s lifeline. …
Cruise Details
0
Porto with Dom Luis Bridge
$4,199
EXPLORE

Portugal's River of Gold

Lisbon-Porto - 10 Day Itinerary aboard Viking River Cruises
  • Tour the Jerónimos Monastery
  • Visit Vila Real's Mateus Palace
  • Explore Castelo Rodrigo
  • Enjoy Salamanca, Spain
Starts / Ends:
Lisbon / Salamanca
Activities:
Archaeological Site Visits, River Cruises, Small Ship Cruises, Wine Tasting
Activity Level:
Variable
Take in the natural beauty and rich history of the Douro River. Experience Lisbon's renaissance, revitalized by trendy galleries and eateries. Explore two of Iberia's most historic university towns: Coimbra, Portugal, and Salamanca, Spain. Tour Porto's port warehouses and enjoy …
Cruise Details
0
Ruins Athina Pronaia temple in Ancient Delphi
$15,696
EXPLORE

Mediterranean Wonders: Sicily, Greece, Sardinia, and Beyond

Spain - Greece - 13 Day Itinerary aboard National Geographic Orion
  • Cruise the Mediterranean Sea
  • Explore standing stones on Menorca
  • Taste Sicilian wine
  • Swim at Kefalonia
  • Explore Delphi and Corinth Canal
Starts / Ends:
Barcelona / Athens
Activities:
Small Ship Cruises
Activity Level:
Variable
On this 13-day Mediterranean Wonders: Sicily, Greece, Sardinia, and Beyond Cruise from Spain to Greece aboard National Geographic Orion, traverse the Mediterranean Sea to explore ancient ruins, medieval towns, and culinary delights from Spain and Sardinia to Corsica and Greece. Walk among …
Cruise Details
0
Visit the town of Pinhao, in the heart of the beautiful Douro Valley
$2,635
EXPLORE

From Portugal to Spain: Porto, the Douro Valley (Portugal) and Salamanca (Spain)

8 Day Itinerary aboard MS Infante Don Henrique
  • Explore Porto
  • Discover Salamanca
  • Experience Vega de Terron
  • Discover Douro Valley
Activities:
River Cruises, Wine Tasting
Activity Level:
Variable
Embark on an 8-day cruise to and from Porto aboard the MS Infante Don Henrique. Cruise through the stunning Douro Valley, filled with breathtaking scenery, historic sites, and unique experiences. Start your journey in the vibrant city of Porto, then travel through Regua to explore the region's …
Cruise Details
0
Visit the historic Belem tower near Lisbon
$9,015
2-for-1
EXPLORE

Lisbon & Secrets of the Douro

Lisbon - Porto - 11 Day Itinerary aboard Emerald Radiance
  • Visit Ruins of Lisbon
  • Experience Roman times.
  • Explore Douro Valley
  • Amaze with eclecticmix architecture
Starts / Ends:
Lisbon / Porto Antigo
Activities:
Archaeological Site Visits, River Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
Start your journey in the Portuguese capital of Lisbon, where the cobbled alleyways and ancient ruins are yours to explore before meeting your Emerald Waterways Star-Ship in Porto. A symbol of Portugal’s birth and growth as a nation, the Douro has long been the country’s lifeline. …
Cruise Details
0
Porto with Dom Luis Bridge
$1,430
EXPLORE

Portugal to Spain - Porto, the Douro Valley and Salamanca

8 Day Itinerary aboard MS Vasco de Gama
  • Admire the city of Porto at night
  • Tour Vila Real by coach
  • Explore the old city of Salamanca
  • Visit Lamego's monumental sanctuary
Activities:
River Cruises, Wine Tasting
Activity Level:
Variable
Be carried away by the charm of the Mediterranean countries. From Portugal to Spain, you will visit Porto, a lively and fascinating city where you can taste its famous wine, or Guimarães, the beating heart of Portugal with a remarkable history that gives it today all its charm. Be guided …
Cruise Details
0
Explore beautiful Barcelona
$12,799
EXPLORE

Timeless Tastes & Treasure

Barcelona - Venice - 15 Day Itinerary aboard World Navigator
  • Visit Barrakka Panoramic Lifts
  • Explore French Riviera and Old Nice
  • Visit the town of Côte d'Azur
  • Do truffle-hunting in Tuscany
Starts / Ends:
Barcelona / Venice
Activities:
Archaeological Site Visits, Local Market Visits, Urban Exploration, Wine Tasting
Activity Level:
Variable
Embark on a 15-day Timeless Tastes & Treasure Cruise from Barcelona to Venice aboard World Navigator. Along Valletta's Grand Harbor, start with the Barrakka Panoramic Lifts, for a sunset with an extended evening in port. Enjoy a late night in Monte Carlo, to explore the scenery of the …
Cruise Details
0
Porto, Portugal Old Town
$8,290
2-for-1
EXPLORE

Secrets of the Douro

Porto - Porto - 8 Day Itinerary aboard Emerald Radiance
  • Visit Quinta do Tedo vineyard
  • Experience Roman times
  • Explore Douro Valley
  • Admire eclectic mix architecture
Starts / Ends:
Lisbon / Porto Antigo
Activities:
Archaeological Site Visits, River Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
Start your voyage in Porto by boarding the Emerald Waterways Star-Ship. The Douro, a symbol of Portugal's origin and growth as a nation, has long served as the country's lifeblood. After leaving the pastel-colored city of Porto, travel across the enchanting countryside. The riverbanks are …
Cruise Details
0
Relax in beautiful Porto
$14,290
2-for-1
EXPLORE

The Unforgettable Douro

Porto to Porto - 11 Day Itinerary aboard Scenic Azure
  • Enjoy a Fado performance
  • Enjoy a variety of activities
  • Explore the Douro Museum
  • Tour charming villages
  • Taste locally-produced wines
Starts / Ends:
Porto / Porto
Activities:
Small Ship Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
Portugal’s Douro River winds through stunning landscapes dotted with timeless towns that have preserved traditional ways of life. From elegant Lamego to Regua and Vega de Terron, find pockets of history and traditional living tucked amid the lush green hillsides of the Douro Valley. Board …
Cruise Details
0
Stop in sunny Salamanca
$11,240
2-for-1
EXPLORE

Delightful Douro with Lisbon

11 Day Itinerary aboard Scenic Azure
  • Visit the Maritime Museum
  • Visit Palacio Nacional
  • Relax and enjoy musical performance
  • Explore the Douro Museum in Regua
Starts / Ends:
Lisbon / Porto
Activities:
River Cruises, Small Ship Cruises, Wine Tasting
Activity Level:
Variable
Discover the beautiful Douro river valley with a relaxing adventure aboard Scenic Azure. Attend an exclusive Sundowners cocktail event on the manicured lawns of the Douro Museum, and watch as the sun sinks beneath the fruitful vines of Régua’s plentiful vineyards. Tour the …
Cruise Details
0
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