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Explore Pittsburgh

Ohio River Cruise

Pittsburgh - Louisville - Example 9 Day Cruise aboard American Melody
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Cruise the Ohio River from Pittsburgh to Louisville on this engaging 9-day river cruise aboard American Melody. Explore Wheeling, Marietta, Cincinnati, Madison, and Louisville while visiting historic districts, museums, and local landmarks. Walk through Victorian streets, tour National Register-listed sites, and learn about the Underground Railroad. Enjoy scenic river views, dramatic bridges, and charming small towns from the ship. Participate in onboard lectures, cultural programs, and tasting experiences. Engage with local history at Churchill Downs, the National Underground Railroad Freedom Center, and the Louisville Slugger Museum. This river adventure combines history, culture, and scenic landscapes for a comprehensive Ohio River experience.
Cycling along the river in PittsburghVisit historic Cincinnati, OhioSunset over the Cincinnati skylineExplore Pittsburgh
Highlights
  • Explore Pittsburgh’s steel heritage and famous American historical sites
  • Walk Wheeling’s cobblestone streets and Victorian-era architecture areas
  • Cruise past Ohio River towns with picturesque riverfront views
  • Visit Louisville Slugger Museum and sample local bourbon during excursion
Places Visited
Activity Level: Variable
Activity options vary depending on destination and operator. Activity level is determined by the range and intensity of activities you choose to participate in. Discuss with your Trip Planner which options are best for you.
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Full Itinerary

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Day 1: Pittsburgh, Pennsylvania

Discover Pittsburgh, Pennsylvania, a historic center of steel production and river commerce that shaped national trade in the 18th and 19th centuries. Check into your hotel and explore the city on your own. Visit landmarks and learn about notable figures such as Carnegie, Heinz, and other influential residents who helped define Pittsburgh’s history.

Day 2: Pittsburgh, Pennsylvania| Embark

Board the ship and settle into your cabin, preparing for the journey ahead. Attend the welcome reception and toast the crew before departure. Watch the Ohio River curve past as Pittsburgh fades behind you.

Cruise along the river, taking in expansive views and passing quaint towns. Observe forests, rolling hills, and peaceful valleys along the route. Spot historic buildings, riverfront communities, and local marinas, each offering a glimpse into the region’s past and daily life.

Day 3: Wheeling, West Virginia

As the birthplace of West Virginia, Wheeling maintains an air of nostalgia with well-preserved Victorian architecture lining cobblestone streets. The diverse range of activities available here offers something for everyone. History buffs can explore the city's rich heritage at the West Virginia Independence Hall or the Victorian-era Center Market. For those seeking cultural experiences, the Capitol Theatre features performances ranging from live music to theatrical productions. Art enthusiasts can venture to the Wheeling Artisan Center, while the Kruger Street Toy & Train Museum delights visitors of all ages.   

Day 4: Marietta, Ohio

This picturesque, charming town rests at the confluence of the Muskingum River and the Ohio River and has five National Register Historic Districts with buildings that date back to the town’s founding in 1788. Explore the first settlement in the Northwest Territory on the north side of the Ohio River. Hear stories of the compelling events that unfolded here which were spotlighted in the recent book entitled, The Pioneers by Pulitzer Prize-winning historian David McCullough. 

The Castle Historic House Museum Experience - Complimentary Excursion
Explore this beautifully preserved, 1855 Gothic-Revival house which is on the National Register of Historic Places. The Castle was once home to some of Marietta's most prominent citizens and the site of many prestigious functions. Hear fascinating stories about its history and learn about of one of the oldest regions in the Northwest Territory.
Activity Level: Medium | ADA ACCESSIBLE: Yes

Marietta Local Loop - Complimentary Excursion
Explore the captivating museums of Marietta at your leisure with the convenient shuttle, making stops at:
Campus Martius and Ohio River Museum - Explore America’s migration west, its earliest native inhabitants, and Marietta’s pioneers. Discover the golden age of the steamboat and learn more about the ecology of the Ohio River system. Outside the museum, visitors can take an escorted exploration of the WP SNYDER JR – the last intact, steam-powered “pool-type” stern-wheeled towboat in the United States.  
Children’s Toy & Doll Museum - Get a glimpse into what entertained and educated children in the late 19th and early 20th centuries. Explore nine rooms, displaying antique and vintage doll collections, including Kewpie dolls, Barbie dolls and GI Joe model dolls, miniature houses, as well as larger models of fairy tale homes such as the Ole’ Woman in the Shoe model and a Hansel and Gretel Gingerbread Doll House. 
Activity Level: Low | ADA Accessible: Yes

Day 5: Day of Cruising

As you cruise along the grand Ohio River, experience the serene beauty of America's heartland. Witness the gentle sweep of greenery along the banks, interspersed with quaint towns that can be seen from the top deck. Partake in a variety of onboard activities designed to enrich your journey, from historical presentations to lively discussions, each adding depth to the stunning vistas that unfold before you. Let the rhythm of the river carry you through landscapes steeped in history, offering a peaceful yet engaging backdrop to your exploration. Each mile traveled is a new chapter in the unfolding story of the Ohio River, inviting you to witness its quiet waves and enduring charm.

Day 6: Cincinnati, Ohio

The dramatic bridges that span the Ohio River provide an impressive scenic welcome to your visit to Cincinnati. As an early shipbuilding and shipping metropolis, the town became known as the “Queen City.”  Your adventures ashore reveal the highlights of this vibrant cultural center which include major sports franchises, a delightful zoo, and a botanical garden, as well as numerous theaters and museums, including the National Underground Railroad Freedom Center, a Smithsonian Affiliate Museum.

Admire the eclectic architecture as you stroll along its charming streets and enjoy the diverse attractions, ranging from the abundant gardens of the Krohn Conservatory to the architectural wonders of St. Mary’s Cathedral Basilica. Get a taste of local cuisine by trying Cincinnati Skyline Chili or stopping for a scoop at Graeter’s ice cream shop, founded in 1868.

National Underground Railroad Freedom Center - Complimentary Excursion
The National Underground Railroad Freedom Center celebrates the brave men and women who came together to create a secret network through which the enslaved could escape to freedom. Their examples of courage, cooperation, and perseverance, is relevant to this day, as you continue to deal with contemporary issues of equality and diversity. 
Activity Level: Low | ADA ACCESSIBLE: Yes

Cincinnati City Experience - Complimentary Excursion
Explore both sides of the river on this fantastic, all-encompassing excursion. Begin in the heart of the city at Fountain Square. Along your journey, view the Contemporary Arts Center, Procter and Gamble’s International Headquarters, and the Taft Museum in beautiful Lytle Park. Learn about Cincinnati’s most well-known landmarks including Union Terminal, Music Hall, Washington Park, Smale Riverfront Park, Bicentennial Commons, the new TQL Stadium, and the Paul Brown Stadium and Great American Ball Park – home of the Bengals and Reds.

Enjoy the old-world charm of Mount Adams with its “shot-gun” row homes and charming district of shops and restaurants. View picturesque Eden Park, home to the Cincinnati Art Museum, Playhouse in the Park, and Krohn Conservatory. 

Cross the Ohio River to Kentucky’s historic Riverside Drive with its antebellum homes. Explore the entertainment district at Newport on the Levee and the World Peace Bell – the largest free-swinging bell in the world.  While in Kentucky, you'll enjoy a breathtaking view of the Cincinnati skyline. 
Activity Level: Low | ADA ACCESSIBLE: Yes

Day 7: Madison, Indiana

A quaint town located on the banks of the Ohio River, Madison is one of the oldest and most charming cities in the state, known for its well-preserved 19th-century architecture. The historic district, listed on the National Register of Historic Places, features over 130 preserved buildings that showcase a mix of Greek Revival, Victorian, and Federal styles.

With several local sites linked to the abolitionist movement, Madison’s rich history includes a significant role in the Underground Railroad. The town also celebrates its heritage during the Madison Regatta, one of the oldest hydroplane races in the U.S.

Considered an outdoor museum of architecture, stroll through the vibrant downtown which abounds with boutique shops, art galleries, and restaurants. Take time to admire the town’s natural beauty, with scenic views of the river and surrounding hills serving as a picturesque backdrop. 

Day 8: Louisville, Kentucky

An impressive waterfront town arching up the hillside, Louisville has a long history of commerce and revelry. The town grew at a portage around the treacherous Falls of the Ohio, now inundated behind the Ohio River’s Markland Dam. The historic importance of river commerce to the town is represented by the “Belle of Louisville” day excursion boat just down the banks, still operating after more than a century. Explore the impressive Churchill Downs to learn about the city’s renowned Kentucky Derby, the oldest continuously held horse race in the country.

Or stop by the Louisville Slugger Museum & Factory to see how the famous baseball bats are made. A visit to the local distillery lift your spirits as you savor samples and learn about the history of Kentucky bourbons.

Kentucky Derby Experience - Complimentary Excursion
Get a behind-the-scenes look at the world-famous Churchill Downs Racetrack. Walk through a portion of the grandstands where thousands of people roar with excitement on Derby Day. Your guide lead you to the rail of the legendary dirt track where every Derby winner has raced, from Aristides to Secretariat and more. Have your camera ready for pictures of the historic track. Hear stories of the early days of the Kentucky Derby through its transformation into the event it is today. Enjoy a viewing of the epic film, The Greatest Race, a 360-degree, 18-minute media experience that make your heart race and your emotions soar. Be treated to Mint Juleps and Derby Pie Bites as you listen to a special presentation by an actual Kentucky Derby Jockey who can answer any questions you may have about this iconic event.
Activity Level: Low | ADA ACCESSIBLE: Yes

Day 9: Louisville, Kentucky| Disembark

  • 1 Breakfast
Enjoy breakfast onboard the ship as you prepare for your journey home. Reflect upon the memorable experiences and the new friendships forged during your time in the cruise.

Thank you for cruising, hoping your voyage was filled with delightful moments that you carry with you. Safe travels home, and looking forward to welcoming you aboard again soon.

Ship/Hotel

American Melody

Dates & Prices

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Deals

Special Offers 23942
Promotional rates are available on select departures for a limited time. These offers cannot be combined with other discounts and are only valid on new bookings.  Please discuss with your trip planner about applicable dates and cabin types.
Applies to select departures

Per person starting at
$5,275 2-3 travelers
Rates are subject to change without notice. Book early to get the best rate.
Single Balcony
Queen-size bed, full-size private bathroom with a full set of amenities, sliding glass doors open to private balcony, satellite TV and DVD player, complimentary WiFi Size: 250 sq. ft., including balcony
Standard Balcony
King-size bed, full-size private bathroom with a full set of amenities, sliding glass doors open to a private balcony, sitting area, writing desk, satellite TV and DVD player, complimentary WiFi Size: 275 sq. ft., including balcony
Deluxe Balcony
King-size bed, full-size private bathroom with a full set of amenities, sliding glass doors open to private balcony, sitting area, writing desk, satellite TV and DVD player, complimentary WiFi, Size: 316 sq. ft., including balcony
Premium Balcony
King-size bed that can convert to two twin beds, full-size private bathroom with a full set of amenities, sliding glass doors open to private balcony, sitting area, writing desk, satellite TV and DVD player, complimentary WiFi. Located on the top deck, these spacious staterooms feature commanding views of the passing river landscapes. Size: 350 sq. ft., including balcony
Veranda Suite
King-size bed that can convert to two twin beds, full-size private bathroom with a full set of amenities, large living area, sliding glass doors open to private balcony, satellite TV and DVD player, complimentary WiFi. Size: 405 sq. ft., including balcony
Grand Suite
Grand Suite
King-size bed, floor-to-ceiling glass windows offering 270-degree panoramic views, large balcony, private dining area, full-size private bathroom with a full set of amenities, satellite TV and DVD player, complimentary WiFi, individual climate control. Each Grand Suite features a separate bedroom and living area, ideal for gathering with family and friends after an invigorating day of exploration. Size: 650 sq. ft., including balcony
Included
  • 8 Breakfasts, 7 Lunches, 7 Dinners
  • 8 Nights Accommodations
  • Accommodations as listed
  • Ground transportation as listed
  • Activities as listed
  • Meals as listed
  • Access to a 24-7 Emergency line while traveling
  • Snacks
  • Onboard Entertainment 
  • Onboard gratuities
  • Port charges and fees
  • Complimentary cocktail parties
  • Dining service
  • WiFi provided by Starlink
  • Wine and beer service each afternoon and evening
  • Resident historians and experts who lead discussions and enlighten as you sail
  • Personalized experiences with a dedicated guest programs staff
Excluded
  • Travel Insurance
  • Personal Expenses
  • Flight costs (please request a quote)
  • Additional excursions during free time
  • Fuel and transportation surcharges (when applicable)
  • Premium and Signature shore excursions

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The trip was terrific with great planning on your part. Most of the adventures were not mainstream and somewhat off the beaten path which made it especially enjoyable!! We felt taken care of and you all were readily available to respond to questions and issues. I would highly recommend your company and friends have already expressed interest based on our pictures and excitement.
Gale Cantor

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