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Explore Louisville Cultural Cruises

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Explore the heart of the American Midwest by embarking on one of Adventure Life's cultural River Cruises to Louisville, Kentucky, this 2025. With 2 meticulously designed tours, you can journey through vibrant cities like St. Louis, Louisville, and Pittsburgh, immersing yourself in the region's rich history and heritage. Experience the laid-back hospitality of Kentucky ports, taste locally-distilled bourbon, and admire historic handicrafts along the way. From the music of Memphis to the artsy vibe of Louisville, these tours offer a relaxed exploration of the cultural gems nestled along the Ohio and Mississippi Rivers. Join us on a trip to discover the charm of small-town America and create unforgettable memories. Contact one of Adventure Life's tour specialists for help planning your next seamless trip.
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Visit historic Memphis, Tennessee
from $6,360
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Mississippi River Gateway Cruise

New Orleans to Louisville - 12 Day Itinerary aboard American Heritage
  • Explore Oak Alley Plantation
  • See Paducah wall murals
  • Explore Sun Studio
  • Visit Elvis Presley’s estate
Starts / Ends
New Orleans / Louisville
Activities
Wildlife Viewing, Village Visits, Urban Exploration, Archaeological Site Visits
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Variable
Embark on a 12-day Mississippi River cruise from New Orleans to Louisville aboard American Heritage. Explore iconic sites like Oak Alley, Vicksburg, and Memphis. Enjoy enriching excursions, Civil War history, live music, and Southern cuisine.
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View the iconic arch when you visit St. Louis, gateway to the west
from $9,240
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Grand Ohio River Cruise

Pittsburgh to St. Louis - 16 Day Itinerary aboard American Melody
  • Explore historic Marietta, Ohio
  • Explore Maysville’s Railroad
  • Visit Louisville’s Churchill Downs
  • Tour Paducah’s wall murals
Starts / Ends
Pittsburgh / St. Louis
Activity Level
Variable
Sail from Pittsburgh to St. Louis on a 16-day Ohio River cruise aboard American Melody. Visit historic towns like Marietta, Cincinnati, Louisville, and Paducah. Discover museums, landmark sites, and cultural excursions while enjoying daily enrichment programs and scenic cruising.
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