Have questions? We're here.

Mississippi

Travel made your way ™
United States
Kayaking
Columbia River
Sunrise over Crown Point at Columbia River
Cumberland River
Explore historic Nashville, Tennessee
Florida
Fort Lauderdale strip aerial view
Hawaii
Halawa Bay on Molokai
Illinois River
Aerial views of Chicago
New England
Springtime in Boston
Ohio River
Pacific Northwest
Bridge over Columbia River to Mount Hood
Tennessee River
unsplash
Chattanooga Tennessee
Washington
Explore the landscape of the Pacific northwest
Talk with an expert
Build your ideal United States trip. Call 1.406.541.2677
Start Planning My Trip
Talk with an expert
Filter (15 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • Mississippi
Visit historic Memphis, Tennessee
from $6,360
Savings
EXPLORE

Mississippi River Gateway Cruise

New Orleans to Louisville - 12 Day Itinerary aboard American Heritage
  • Explore Oak Alley Plantation
  • See Paducah wall murals
  • Explore Sun Studio
  • Visit Elvis Presley’s estate
Starts / Ends
New Orleans / Louisville
Activities
Village Visits, Archaeological Site Visits, Urban Exploration, Wildlife Viewing
Activity Level
Variable
Embark on a 12-day Mississippi River cruise from New Orleans to Louisville aboard American Heritage. Explore iconic sites like Oak Alley, Vicksburg, and Memphis. Enjoy enriching excursions, Civil War history, live music, and Southern cuisine.
Cruise Details
0
Explore historic New Orleans
from $4,255
Savings
EXPLORE

Highlights of the Mississippi Cruise

New Orleans Roundtrip - 8 Day Itinerary aboard American Melody
  • Explore the antebellum of Natchez
  • Visit historic Civil War sites
  • Discover Oak Alley's historic charm
  • Visit charming ports and cities
Starts / Ends
New Orleans / New Orleans
Activities
Local Market Visits
Activity Level
Variable
The American Melody hosts this 8-day Mississippi River cruise from New Orleans. Explore historic plantations, Civil War sites, and charming towns. Immerse in the rich culture, cuisine, and music of the Deep South.
Cruise Details
0
Visit historic Minneapolis
from $15,890
Savings
EXPLORE

Complete Mississippi River

New Orleans - St. Paul - 23 Day Itinerary aboard American Melody
  • Explore Natchez's Grand Homes
  • Visit Oak Alley
  • Delve into Baton Rouge's history
  • Unravel Vicksburg's Civil War
Starts / Ends
New Orleans / St. Paul
Activities
Wine Tasting
Activity Level
Variable
Discover the Mighty Mississippi on a 23-day cruise covering 10 states aboard American Melody. Immerse in history, culture, and cuisine from New Orleans to Minneapolis, exploring charming ports along the way.
Cruise Details
0
13-15 of 15 Results
  • 1
  • 2

Real experience. Honest advice.

Talk with an expert trip planner 1.800.344.6118

Plan My Trip
Eric Niskanen Adventure Life employee profile
Eric N.
The beautiful lake with the waterfalls in Plitvička Jezera, Croatia
United States

Chat Mississippi with a specialist

Our team is waiting and ready to talk with you about your next adventure. So go ahead and book an appointment with one of our specialized trip planners.

Let's Chat
1.800.344.6118

Where is your next adventure?

Contact Chat Call
More Reasons

Why Travel With Adventure Life

All News

Featured In

How it Works

Connect

No cost, no commitment. Talk with our experts about your dream trip.

Plan

Share your travel style—we match you with the right itinerary or create one just for you.

Book

Lock in knowing every detail is handled and you’re fully supported.

Travel

Enjoy a seamless journey—and unlock 5% off your next adventure.

United States Travel Guide

Top United States Travel Destinations

United States Trips by Departure Date

Top Experiences in United States

United States Trips by Duration

United States Trips by Activity

Eric Niskanen Adventure Life employee profile
Eric N
Plan My Trip
We love travel, talk with an expert 1.800.344.6118