Have questions? We're here.
Boat floating along the Mekong River

Top Mekong River Trips & Tours in April 2026

Travel made your way
Talk with an expert
Build your ideal Mekong River trip. Call 1.406.541.2677
Start Planning My Trip
Filter (40 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • Mekong River
Local moving cattle through the fields
from $5,828
EXPLORE

Riches of the Mekong

16 Day Itinerary aboard MS Amadara
  • Explore Hanoi’s rich heritage
  • Cruise Ha Long’s stunning waters
  • Discover Angkor Thom’s grandeur
  • Sail Mekong’s timeless villages
Activities
Hiking
Activity Level
Variable
Embark on a 16-day cruise aboard the MS Amadara, exploring Hanoi, Ha Long Bay, Siem Reap, and Ho Chi Minh City. Discover ancient temples, cruise the Mekong River, visit charming villages, and experience the vibrant blend of history and modern life in Vietnam and Cambodia.
Cruise Details
0
Bike ride by Angkor Wat Temple
from $10,150
Up to 30%
EXPLORE

Wonders of Cambodia, Vietnam and the Mekong

Siem Reap - Ho Chi Minh - 13 Day Itinerary aboard Emerald Harmony
  • Explore ancient Angkor Thom
  • Discover temples at Ta Prohm
  • Visit Kampong Tralach
  • Tour Vietnam’s rural life
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Wildlife Viewing
Activity Level
Variable
Experience a 13-day cruise on the Emerald Harmony, starting in Siem Reap with guided tours of Angkor Wat and other iconic sites. Journey through the Mekong River, exploring Phnom Penh and the Mekong Delta, before concluding with two nights in Ho Chi Minh City, blending culture and heritage in Cambodia and Vietnam.
Cruise Details
0
Bike in front of Angkor Wat
from $5,494
EXPLORE

From the Mekong Delta to the Temples of Angkor & Hanoi and Halong Bay

Hanoi to Angkor Temples - 14 Day Itinerary aboard RV Indochine II
  • Explore Hanoi’s historic sites
  • Learn Cambodian history
  • Ride sampans through canals
  • Cruise scenic Halong Bay
Starts / Ends
Hanoi / Siem Reap
Activity Level
Variable
Travel from Hanoi to Siem Reap on a 14-day cruise-tour aboard RV Indochine II. Explore Vietnam’s capital, cruise Halong Bay, and visit Ho Chi Minh City. Journey along the Mekong River to discover floating villages, bustling markets, and temples.
Cruise Details
0
Angkor Wat
from $5,294
EXPLORE

From the Temples of Angkor to the Mekong Delta & Hanoi and Halong Bay

Siem Reap to Halong Bay - 14 Day Itinerary aboard RV Indochine II
  • Angkor Wat exploration
  • Explore Tonle Sap villages
  • Explore Sa Dec markets
  • Discover Hanoi's historic sites
Starts / Ends
Siem Reap / Hanoi
Activities
Local Market Visits, Land & Sea Exploration, Urban Exploration
Activity Level
Variable
Explore Vietnam and Cambodia on a 14-day cruise combining river cruising aboard RV Indochine II and cultural tours. Visit Angkor temples, Tonle Sap Lake, Phnom Penh, Chau Doc, Sa Dec, Ho Chi Minh City, Hanoi, and Halong Bay. Discover vibrant markets, ancient pagodas, floating villages, and historic landmarks.
Cruise Details
0
The Vinh Trang Temple in My Tho
from $4,784
EXPLORE

From the Mekong Delta to the Temples of Angkor & Hanoi and Halong Bay

Hanoi to Angkor Temples - 14 Day Itinerary aboard RV Indochine
  • Experience Hanoi city tour
  • Cruise along Halong Bay's islands
  • Explore Ho Chi Minh landmarks
  • Explore My Tho bee farm
Starts / Ends
Hanoi / Siem Reap
Activity Level
Variable
Discover Vietnam and Cambodia on a 14-day cruise from Hanoi to Siem Reap aboard RV Indochine. Cruise Halong Bay, explore Ho Chi Minh City, visit Phnom Penh, and marvel at Angkor temples. Enjoy guided tours, local markets, floating villages, and authentic cuisine with unique cultural experiences along the Mekong River.
Cruise Details
0
Cycling along the bridge
from $1,337
EXPLORE

Cycling the Mekong Delta

Vietnam Small Group Tour - 7 Day Itinerary
  • Explore Ho Chi Minh City
  • See the floating market in Cai Be
  • Visit the Khmer templ in Tra Vinh
  • Explore Can Tho's charming villages
  • See the rice paddies in Long Xuyen
  • Discover Chau Doc' diverse culture
Starts / Ends
Ho Chi Minh City / Ho Chi Minh City
Activities
Biking, Homestays
Activity Level
Moderate
Cycle through the Mekong Delta on this 7-day tour from Ho Chi Minh City. Explore vibrant villages, floating markets, and authentic river life on a route that blends active cycling with local culture. Perfect for travelers seeking an extended Mekong River tour, this tour offers a deep dive into the region's scenery and traditions.
Tour Details
0
Boy on wooden fishing boat
from $1,951
EXPLORE

Mekong River - Downstream - Low water

Siem Reap to Phnom Penh - 5 Day Itinerary aboard Jayavarman
  • Explore the mighty Mekong River
  • Discover pre-Angkorian temples
  • Explore Tonle's riverine
  • Learn about Phnom Penh
Starts / Ends
Siem Reap / Phnom Penh
Activity Level
Variable
Embark on a 5-day cruise along the Mekong River from Siem Reap to Phnom Penh with the Jayavarman, and cruise the expansive Mekong Delta to discover the pre-Angkorian temples and culture of Cambodia.
Cruise Details
0
Royal Palace and Silver Pagoda
from $10,750
Up to 30%
EXPLORE

Wonders of Vietnam, Cambodia and the Mekong

Ho Chi Minh City - Siem Reap - 13 Day Itinerary aboard Emerald Harmony
  • Explore Ho Chi Minh City’s streets
  • Venture Cu Chi’s legendary tunnel
  • Witness river life along Ben Tre
  • Stroll Sa Dec’s colorful markets
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Join a 13-day cruise through Vietnam and Cambodia aboard the Emerald Harmony, starting in Ho Chi Minh City and exploring the Mekong Delta’s villages. Conclude your adventure in Siem Reap, visiting the remarkable Angkor Wat temple complex.
Cruise Details
0
Killing Fields, Phnom Penh
from $11,735
Up to 30%
EXPLORE

Luxury Mekong and Temple Discovery Cruise

Siem Reap - Ho Chi Minh - 11 Day Itinerary aboard Scenic Spirit
  • Uncover Tan Chau’s cultural gems
  • Admire Angkor Wat’s divine beauty
  • Visit Banteay Srei
  • Explore Siem Reap’s French colonial
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Experience an 11-day cruise on the Scenic Spirit through Cambodia and Vietnam, starting in Siem Reap with visits to Angkor Wat and local markets. Enjoy a Mekong River journey with stops at various towns, cultural activities, and end your trip in Ho Chi Minh City.
Cruise Details
0
Sunset over the Mekong River
from $13,095
Up to 30%
EXPLORE

Treasures of the Mekong

Ho Chi Minh City - Siem Reap - 13 Day Itinerary aboard Scenic Spirit
  • Explore Ho Chi Minh City’s tunnels
  • Visit Cai Be’s orchard island
  • Uncover Sa Dec’s markets
  • Admire Oudong’s serene monastery
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Set sail on a 13-day cruise from Ho Chi Minh City to Siem Reap aboard the Scenic Spirit, exploring the rich culture and history of Vietnam and Cambodia. Enjoy activities like cooking classes, temple tours, and immersive experiences, including a monk’s blessing and a gala dinner.
Cruise Details
0
Khone Pha Pheng waterfall, a famous waterfall in Southern of Laos
from $1,172
EXPLORE

Southern Laos

Lao's Mekong River - 5 Day Itinerary
  • Explore Wat Phou Ancient Ruins
  • Cruise Mekong River Scenic Islands
  • View Khone Phapheng Massive Falls
  • Cycle Don Khone Peaceful Trails
  • Visit Liphi Cascading Waterfalls
Starts / Ends
Pakse / Pakse
Activity Level
Relaxed
Discover the hidden gems of Southern Laos on this immersive 5-day private adventure. You explore the ancient UNESCO ruins of Wat Phou, cruise the Mekong to the peaceful 4000 Islands, and experience local life with a fishing trip and island BBQ. The trip concludes with the stunning waterfalls and tribal villages of the cool Bolaven Plateau.
Tour Details
0
The beautiful Vinh Trang temple near My Tho
from $3,250
EXPLORE

Mekong River - Upstream - Low water

Saigon - Siem Reap - 8 Day Itinerary aboard Jayavarman
  • Aboard a luxury riverboat in Mekong
  • Visit Cai Be workshops
  • Explore Tan Phong Island
  • Cruise the Tonle River
  • Meet monks in Angkor Ban
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Village Visits, Archaeological Site Visits, Cooking Classes
Activity Level
Variable
Sail the Mekong River aboard the Jayavarman on an 8-day cruise from Saigon to Siem Reap. Discover local life along the river, from Vietnam’s craft villages and island communities to Cambodia’s temples, silk weaving villages, and cultural traditions.
Cruise Details
0
Explore the floating village of Tonle Sap
from $4,800
EXPLORE

Mekong Discovery - Phnom Penh to Ho Chi Minh

4 Day Itinerary aboard Aqua Mekong
  • Walk through verdant plantations
  • Learn about local traditions
  • Visit Vinh Trang Pagoda
  • Tour Sa Dec markets
Activity Level
Variable
Embark the luxurious Aqua Mekong in Phnom Penh, Cambodia, on this 4-day discovery cruise along the Mekong River to Ho Chi Minh City, Vietnam. You'll peruse vibrant markets and visit typical Mekong Delta villages while getting to know local cultures and ways of life, with a visit to Vinh Trang Pagoda and opportunities to bike along the way.
Cruise Details
0
Phnom Penh Royal Palace complex
from $10,290
Up to 30%
EXPLORE

Luxury Mekong

Siem Reap to Ho Chi Minh City - 8 Day Itinerary aboard Scenic Spirit
  • Explore beauty of Angkor Ban
  • Visit architecture of Phnom Penh
  • Visit the Royal Palace
  • Sail through Vinh Te canal
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Experience an 8-day cruise along the Mekong River from Siem Reap to Ho Chi Minh on the Scenic Spirit, blending cultural exploration with relaxation. Discover historical sites and local traditions while enjoying luxurious comfort and the region's vibrant contrasts.
Cruise Details
0
Houses of Tonle Sap
from $1,951
EXPLORE

Mekong River - Upstream - Low water

Phnom Penh to Siem Reap - 5 Day Itinerary aboard Jayavarman
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • See Kampong Luong crafts
Starts / Ends
Phnom Penh / Siem Reap
Activity Level
Variable
Take this 5-day Low Water Mekong River cruise from Phnom Penh to Siem Reap aboard the Jayavarman. Travel across the mighty Mekong Delta to get an inside look at Cambodian culture. Stop in charming port towns and immerse yourself in the city's culture and history.
Cruise Details
0
Royal Palace in Phnom Penh
from $2,071
EXPLORE

Mekong River - Upstream - Low water

Phnom Penh to Siem Reap - 5 Day Itinerary aboard The Jahan
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit a local home in Kampong Cham
Starts / Ends
Phnom Penh / Siem Reap
Activity Level
Variable
Join this 5-day Mekong River cruise from Phnom Penh to Siem Reap. Travel across the mighty Mekong delta to get an inside look at Cambodian culture. Stop in charming port towns and immerse yourself in the city's culture and history.
Cruise Details
0
Boat floating along the Mekong River
from $2,071
EXPLORE

Mekong River - Downstream - Low water

Siem Reap to Phnom Penh - 5 Day Itinerary aboard The Jahan
  • Discover Mekong Delta
  • Explore via Tuk-tuk
  • Khmer art at National Museum
  • Cambodia's architecture
Starts / Ends
Siem Reap / Phnom Penh
Activity Level
Variable
Join this 5-Day Low Water Serenity Cruise Expedition aboard The Jahan from Siem Reap to Phnom Penh, and travel across the mighty Mekong Delta to discover the ancient pre-Angkorian temples and Cambodian culture.
Cruise Details
0
Aerial view of Angkor Wat
from $12,395
Up to 30%
EXPLORE

Treasures of the Mekong

Siem Reap - Ho Chi Minh - 13 Day Itinerary aboard Scenic Spirit
  • Discover Siem Reap’s ancient temple
  • Explore Banteay Srei’s history
  • Marvel at Bayon’s Ta Prohm ruins
  • Sample Vietnamese flavors
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Embark on a 13-day journey through Cambodia and Vietnam, starting in Siem Reap with tours of Angkor Wat and a luxurious private gala dinner. Cruise the Mekong River aboard Scenic Spirit, visiting traditional villages and ending in Ho Chi Minh City, where you can explore the Cu Chi Tunnels and War Museum.
Cruise Details
0
19-36 of 40 Results

Top Mekong River Travel Destinations

Mekong River Trips by Departure Date

Top Experiences in Mekong River

Mekong River Trips by Duration

Mekong River Trips by Activity

More Reasons

Why Travel With Adventure Life

All News

Recognized By