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Top Mekong River Trips & Tours in May 2026

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Discover Mekong River in May 2026 on one of these 11 tours hand-selected by the travel experts at Adventure Life. Explore the best of during May 2026 as you enjoy Local Market Visits, Village Visits, Archaeological Site Visits, Wildlife Viewing, and Cooking Classes. Prices for trips in May 2026 range from $0 to $22,095 for a vacation of 5 to 13 days. Choose any of the below 11 itineraries in May 2026 and customize it when you contact one of Adventure Life's expert Mekong River trip planners.
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Bike ride by Angkor Wat Temple
from $10,150
2for1
EXPLORE

Wonders of Cambodia, Vietnam and the Mekong

Siem Reap - Ho Chi Minh - 13 Day Itinerary aboard Emerald Harmony
  • Explore ancient Angkor Thom
  • Discover temples at Ta Prohm
  • Visit Kampong Tralach
  • Tour Vietnam’s rural life
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Local Market Visits, Village Visits, Wildlife Viewing, Archaeological Site Visits
Activity Level
Variable
Experience a 13-day cruise on the Emerald Harmony, starting in Siem Reap with guided tours of Angkor Wat and other iconic sites. Journey through the Mekong River, exploring Phnom Penh and the Mekong Delta, before concluding with two nights in Ho Chi Minh City, blending culture and heritage in Cambodia and Vietnam.
Cruise Details
0
Royal Palace and Silver Pagoda
from $10,150
2for1
EXPLORE

Wonders of Vietnam, Cambodia and the Mekong

Ho Chi Minh City - Siem Reap - 13 Day Itinerary aboard Emerald Harmony
  • Explore Ho Chi Minh City’s streets
  • Venture Cu Chi’s legendary tunnel
  • Witness river life along Ben Tre
  • Stroll Sa Dec’s colorful markets
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Join a 13-day cruise through Vietnam and Cambodia aboard the Emerald Harmony, starting in Ho Chi Minh City and exploring the Mekong Delta’s villages. Conclude your adventure in Siem Reap, visiting the remarkable Angkor Wat temple complex.
Cruise Details
0
Killing Fields, Phnom Penh
from $11,735
2for1
EXPLORE

Luxury Mekong and Temple Discovery Cruise

Siem Reap - Ho Chi Minh - 11 Day Itinerary aboard Scenic Spirit
  • Uncover Tan Chau’s cultural gems
  • Admire Angkor Wat’s divine beauty
  • Visit Banteay Srei
  • Explore Siem Reap’s French colonial
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Experience an 11-day cruise on the Scenic Spirit through Cambodia and Vietnam, starting in Siem Reap with visits to Angkor Wat and local markets. Enjoy a Mekong River journey with stops at various towns, cultural activities, and end your trip in Ho Chi Minh City.
Cruise Details
0
Sunset over the Mekong River
from $12,395
2for1
EXPLORE

Treasures of the Mekong

Ho Chi Minh City - Siem Reap - 13 Day Itinerary aboard Scenic Spirit
  • Explore Ho Chi Minh City’s tunnels
  • Visit Cai Be’s orchard island
  • Uncover Sa Dec’s markets
  • Admire Oudong’s serene monastery
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Land & Sea Exploration, Cooking Classes
Activity Level
Variable
Set sail on a 13-day cruise from Ho Chi Minh City to Siem Reap aboard the Scenic Spirit, exploring the rich culture and history of Vietnam and Cambodia. Enjoy activities like cooking classes, temple tours, and immersive experiences, including a monk’s blessing and a gala dinner.
Cruise Details
0
Khone Pha Pheng waterfall, a famous waterfall in Southern of Laos
from $1,143
EXPLORE

Southern Laos

Lao's Mekong River - 5 Day Itinerary
  • Explore Wat Phou Ancient Ruins
  • Cruise Mekong River Scenic Islands
  • View Khone Phapheng Massive Falls
  • Cycle Don Khone Peaceful Trails
  • Visit Liphi Cascading Waterfalls
Starts / Ends
Pakse / Pakse
Activity Level
Relaxed
Discover the hidden gems of Southern Laos on this immersive 5-day private adventure. You explore the ancient UNESCO ruins of Wat Phou, cruise the Mekong to the peaceful 4000 Islands, and experience local life with a fishing trip and island BBQ. The trip concludes with the stunning waterfalls and tribal villages of the cool Bolaven Plateau.
Tour Details
0
Phnom Penh Royal Palace complex
from $10,290
2for1
EXPLORE

Luxury Mekong

Siem Reap to Ho Chi Minh City - 8 Day Itinerary aboard Scenic Spirit
  • Explore beauty of Angkor Ban
  • Visit architecture of Phnom Penh
  • Visit the Royal Palace
  • Sail through Vinh Te canal
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Urban Exploration
Activity Level
Variable
Experience an 8-day cruise along the Mekong River from Siem Reap to Ho Chi Minh on the Scenic Spirit, blending cultural exploration with relaxation. Discover historical sites and local traditions while enjoying luxurious comfort and the region's vibrant contrasts.
Cruise Details
0
Aerial view of Angkor Wat
from $12,395
2for1
EXPLORE

Treasures of the Mekong

Siem Reap - Ho Chi Minh - 13 Day Itinerary aboard Scenic Spirit
  • Discover Siem Reap’s ancient temple
  • Explore Banteay Srei’s history
  • Marvel at Bayon’s Ta Prohm ruins
  • Sample Vietnamese flavors
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Embark on a 13-day journey through Cambodia and Vietnam, starting in Siem Reap with tours of Angkor Wat and a luxurious private gala dinner. Cruise the Mekong River aboard Scenic Spirit, visiting traditional villages and ending in Ho Chi Minh City, where you can explore the Cu Chi Tunnels and War Museum.
Cruise Details
0
Oudong, the old capital city of Cambodia
from $11,735
2for1
EXPLORE

Luxury Mekong and Temple Discovery Cruise

Ho Chi Minh City - Siem Reap - 11 Day Itinerary aboard Scenic Spirit
  • Explore Cai Be’s orchards
  • Discover Sa Dec’s wet market
  • Witness silk weaving on Silk Island
  • Ascend Wat Hanchey for Mekong views
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Join an 11-day cruise on the Scenic Spirit from Ho Chi Minh City to Siem Reap, cruising the Mekong River and exploring vibrant floating markets and rich cultural sites. Discover the Khmer Empire’s legacy, including ancient temples and riverside villages that showcase local life in Vietnam and Cambodia.
Cruise Details
0
Royal Palace in Phnom Penh
from $8,790
2for1
EXPLORE

Majestic Mekong River Cruise

Ho Chi Minh City - Phnom Penh - 8 Day Itinerary aboard Emerald Harmony
  • Navigate Vietnam’s Cho Gao Canal
  • Visit Tan My floating hamlet
  • Explore Sa Dec markets
  • Discover My An Hung village
Starts / Ends
Ho Chi Minh City / Oudong
Activity Level
Variable
Experience an 8-day cruise on the Emerald Harmony from Ho Chi Minh to Phnom Penh, exploring the Mekong Delta, local communities, and historic sites. Enjoy onboard cultural performances, a Tuk Tuk ride in the capital, and a Buddhist blessing at Oudong Temple.
Cruise Details
0
Ben Tre biking on a country lane
from $1,012
EXPLORE

Biking the Mekong Delta

3 Day Itinerary
  • Enjoy home-cooked meals
  • Cycle through small Delta villages
  • Explore Cai Rang Floating Market
Starts / Ends
Ho Chi Minh City / Ho Chi Minh City
Activity Level
Moderate
Cycle through small villages, past rice fields, and to vibrant markets as you explore the Mekong Delta on this 3-day Vietnam extension. Ride through Cai Be, Vinh Long, and Can Tho, exploring rural landscapes, the famous Cai Rang Floating Market, and local culture. Extend your Vietnam tour with this intimate exploration of the Mekong Delta region.
Tour Details
0
Boat floating along the Mekong River
EXPLORE

Experience the Mekong by Cruise

1 Day Itinerary
  • Visit a candy mill
  • Visit a coconut workshop
  • Enjoy biking or ride on a rickshaw
Starts / Ends
Mekong River / Mekong River
Activities
Biking
Activity Level
Relaxed
This one-day Vietnam tour extension includes a cruise along the Mekong River and visits to other scenic locations. Visit Ben Tre, My Long, a coconut workshop, a bee garden, a candy mill, and a farmer's house, and ride a rickshaw past coconut trees and vegetable farms.
Tour Details
0
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