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Top Mekong River Trips & Tours in April 2026

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Discover Mekong River in April 2026 on one of these 38 tours hand-selected by the travel experts at Adventure Life. Explore the best of during April 2026 as you enjoy Village Visits, Local Market Visits, Archaeological Site Visits, Land & Sea Exploration, and Biking. Prices for trips in April 2026 range from $0 to $20,055 for a vacation of 5 to 16 days. Choose any of the below 38 itineraries in April 2026 and customize it when you contact one of Adventure Life's expert Mekong River trip planners.
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    • Mekong River
Phnom Penh Royal Palace complex
from $1,825
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard The Jahan
  • Observed locals along the river
  • See Cai Be’s rice & candy making
  • Explore the Gieng Island
  • Visit Phnom Penh cultural sites
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jahan. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.
Cruise Details
0
Phnom Penh Golden Temple
from $3,620
EXPLORE

Mekong River - Upstream - Low water

Saigon - Siem Reap - 8 Day Itinerary aboard The Jahan
  • Visit Phnom Penh landmarks
  • Explore Kampong Laeang pottery
  • Meet Binh Thanh weavers
  • Explore Angkor Ban village
Starts / Ends
My Tho / Siem Reap
Activity Level
Variable
Journey 8 days from Saigon to Siem Reap aboard The Jahan, exploring the Mekong River’s changing landscapes and riverside life. Visit workshops in Cai Be, fruit gardens on Tan Phong Island, and communities in Cambodia that craft silver, weave silk, and make mats. Discover Phnom Penh, Angkor Ban, and the temples near Kampong Cham.
Cruise Details
0
Everyday life in Vietnam
from $2,849
EBD $4000
EXPLORE

Charms of the Mekong - Cruise Only

Ho Chi Minh - Siem Reap - 8 Day Itinerary aboard MS Amadara
  • Explore Cai Be’s vibrant workshops
  • Discover Sa Dec history
  • Visit Phnom Penh landmarks
  • Experience Oknhatey, silk weaving
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Embark on an 8-day river cruise aboard the MS Amadara, starting in Ho Chi Minh City, a vibrant blend of history and modernity. Cruise the Mekong River, exploring villages, pagodas, and markets and experiencing local traditions, including a monk’s blessing and artisan crafts.
Cruise Details
0
The colorful Tonle Sap village
from $10,570
EXPLORE

Mekong Expedition - Ho Chi Minh to Siem Reap (Extension)

Low water - 8 Day Itinerary aboard Aqua Mekong
  • Discover My An Hung
  • Enjoy a traditional performance
  • Learn to cook Mekong dishes
  • Visit Cambodia's National Museum
  • Past by Buddhist temples
Activity Level
Variable
From Ho Chi Minh, Vietnam to Phnom Penh, Cambodia, luxurious Aqua Mekong takes you on this 8-day Mekong River cruise, visiting Buddhist temples, local villages & markets, and touring Chau Doc, Kampong Chhnang, Kampong Tralach, Koh Oknha Tey, and Sa Dec.
Cruise Details
0
Royal Palace and Silver Pagoda
from $1,712
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard Jayavarman
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit the Gieng Island
Starts / Ends
Phnom Penh / Ho Chi Minh City
Activity Level
Variable
Cruise downstream on the Mekong River in majestic style aboard the Jayavarman on this 4-day journey from Phnom Penh to Saigon. Learn about the culture and heritage with visits to rural villages, historic pagodas, and colorful markets
Cruise Details
0
Traditional mat-making
from $1,825
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard The Jahan
  • Hear Khmer Rouge survivor story
  • Explore Gieng Island
  • Explore My An Hung Village
  • Discover water hyacinth weaving
  • Experience Tan Phong Island
Starts / Ends
Phnom Penh / Ho Chi Minh City
Activities
Biking
Activity Level
Variable
On this 4-day journey from Phnom Penh to Saigon, cruise downstream on the lower Mekong River in majestic style aboard the Jahan. See the stunning scenery and discover the culture and history of the various towns along the mighty Mekong.
Cruise Details
0
Woman on a boat in Vietnam
from $2,296
EXPLORE

From the Mekong Delta to Siem Reap

Ho Chi Minh City - Siem Reap - 9 Day Itinerary aboard RV Indochine II
  • Join a tour of Ho Ci Minh City
  • Observe Chau Doc´s vibrant market
  • Experience a trip in a “tuk tuk”
  • See Kampong Chhnang´s fish farms
Activity Level
Variable
Discover the culture and history of Vietnam & Cambodia on this 9-day cruise from Ho Chi Minh City to Siem Reap aboard the RV Indochine II, departing from Vietnam's Ho Chi Minh City towards Cambodia's Siem Reap, with stops in My Tho & Phnom Penh along the way.
Cruise Details
0
Enjoy the Mekong’s tranquil waters as colorful blooms and a rustic riverside home set a relaxed, local vibe.
from $2,849
EBD $4000
EXPLORE

Riches of the Mekong - Cruise Only

8 Day Itinerary aboard MS Amadara
  • Explore Angkor Ban village
  • Visit Oknhatey, Silk Island
  • Tour Phnom Penh highlights
  • Discover Oudong, royal capital
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Embark on an 8-day river cruise from Siem Reap to Ho Chi Minh aboard the MS Amadara, exploring rural villages, bustling markets, and historic sites. Experience Cambodia and Vietnam’s rich culture through artisan crafts, temple visits, and unique rides by oxcart, tuk-tuk, and trishaw.
Cruise Details
0
The floating village of Tonle Sap, Cambodia
from $6,400
EXPLORE

Mekong Explorer - Ho Chi Minh to Siem Reap (Extension)

5 Day Itinerary aboard Aqua Mekong
  • Enjoy a visit to a local's home
  • Walk through verdant plantations
  • Meet & interact with Buddhist Monks
  • Bike through Long Khanh
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
Board the Aqua Mekong in My Tho for a 5-day Mekong River cruise of Cambodia & Vietnam, including stops in Ho Chi Minh City, Phnom Penh, and Long Son Pagoda atop Sam Mountain. Travel back in time as you cruise upriver through the thriving Mekong Delta past floating villages, colonial vestiges, and gilded pagodas.
Cruise Details
0
Flower farms in Sa Dec, Vietnam
from $2,079
EXPLORE

From the Mekong Delta to Siem Reap

Ho Chi Minh City to Siem Reap - 9 Day Itinerary aboard RV Indochine
  • Visit Ho Chi Minh landmarks
  • Cruise across Tonle Sap Lake
  • Explore Sa Dec’s Huynh Thuy Le
  • Visit Chau Doc temples
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Urban Exploration
Activity Level
Variable
Embark on a 9-day Mekong River cruise aboard RV Indochine through Vietnam and Cambodia. Begin in Ho Chi Minh City and travel to Siem Reap, exploring temples, pagodas, markets, floating villages, and cultural landmarks along the way. Enjoy guided city tours, traditional crafts, and authentic cuisine.
Cruise Details
0
Statues and intricate relief carvings inside Angkor Wat
from $3,725
EXPLORE

From the Angkor Temples to the Mekong Delta

Siem Reap to Ho Chi Minh City - 11 Day Itinerary aboard RV Indochine II
  • Visit Angkor Wat temples
  • Explore Phnom Penh landmarks
  • Visit Cu Chi tunnels in Saigon
  • Discover Koh Chen crafts
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Local Market Visits, Land & Sea Exploration
Activity Level
Variable
Embark on an 11-day Mekong River cruise through Vietnam and Cambodia aboard RV Indochine II. Start in Siem Reap with Angkor temples, then sail across Tonle Sap Lake and explore Phnom Penh, Chau Doc, Sa Dec, Cai Be, and Ho Chi Minh City. Visit floating villages, historic landmarks, and cultural sites.
Cruise Details
0
Aerial view of Angkor Wat
from $3,215
EXPLORE

From the Mekong Delta to the Angkor Temples

Ho Chin Min City to Angkor - 11 Day Itinerary aboard RV Indochine
  • Visit Ho Chi Minh landmarks
  • Cu Chi tunnels tour
  • Explore Angkor Wat temples
  • Tour Sa Dec historic house
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Experience an 11-day Mekong River cruise from Vietnam to Cambodia aboard RV Indochine. Explore Ho Chi Minh City landmarks, My Tho canals, Phnom Penh palaces, and Siem Reap’s Angkor temples. Visit bustling markets, floating villages, craft villages, and historic sites. Discover culture, tradition, and history on a unique river adventure through Southeast Asia.
Cruise Details
0
Floating Market in Cai Be
from $1,712
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard Jayavarman
  • Observed locals along the river
  • See the floating market in Cai Be
  • Explore the Gieng Island
  • Visit Phnom Penh cultural sites
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jayavarman. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.
Cruise Details
0
Sunset over the Mekong River
from $3,620
No SS
EXPLORE

Mekong River - Downstream - Low water

Siem Reap to Saigon - 8 Day Itinerary aboard The Jahan
  • Discover Gieng Island Workshops
  • Explore Angkor Ban Village
  • Tour Phnom Penh Landmarks
  • Visit Binh Thanh Island
Starts / Ends
Siem Reap / My Tho
Activities
Spa Relaxation
Activity Level
Variable
Sail for 8 days aboard the Jahan from Siem Reap to Saigon, uncovering the heart of Cambodia and Vietnam along the Mekong River. Visit floating villages, temples, and traditional workshops in Phnom Penh, Kampong Tralach, and the Mekong Delta. Enjoy cultural encounters, local cuisine, and daily guided excursions.
Cruise Details
0
Boat floating along the Mekong River
from $3,250
No SS
EXPLORE

Mekong River - Downstream - Low water

Siem Reap to Saigon - 8 Day Itinerary aboard Jayavarman
  • Explore Angkor Ban village
  • Discover Phnom Penh’s heritage
  • Visit Gieng Island workshops
  • Experience My An Hung life
  • Savor local culinary traditions
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Village Visits, Archaeological Site Visits, Cooking Classes
Activity Level
Variable
Sail aboard the Jayavarman on an 8-day Mekong River cruise from Siem Reap to Saigon. Explore riverside villages, ancient temples, and vibrant delta communities while enjoying authentic Cambodian and Vietnamese culture, cuisine, and scenic river life.
Cruise Details
0
Monks outside the temple
from $4,800
EXPLORE

Mekong Discovery - Phnom Penh to Siem Reap (Extension)

Low water - 4 Day Itinerary aboard Aqua Mekong
  • Learn about Buddhist meditation
  • Ride an ox-cart along the Tonle Sap
  • Visit the National Museum
Activity Level
Variable
Board the Aqua Mekong for an excellent 4-day round-trip cruise from Phnom Penh along the Tonle Sap River. Along the way, you'll learn about a uniquely Buddhist practice at the Vipassana Dhura Mandala, enjoy a unique ox-cart ride, and see the Khmer Art Collection at the National Museum of Cambodia.
Cruise Details
0
Kampong Chhnang
from $5,828
EXPLORE

Charms of the Mekong

16 Day Itinerary aboard MS Amadara
  • Explore Ho Chi Minh vibrant city
  • Visit Phnom Penh historic palaces
  • Discover Cai Be markets
  • Tour Siem Reap ancient temples
Starts / Ends
Ho Chi Minh City / Hanoi
Activity Level
Variable
Embark on a 16-day cruise aboard the MS Amadara. Explore the Mekong, visit rural villages and ancient temples, and discover Angkor’s UNESCO sites in Siem Reap before concluding with an overnight stay at Ha Long Bay.
Cruise Details
0
Local moving cattle through the fields
from $5,828
EXPLORE

Riches of the Mekong

16 Day Itinerary aboard MS Amadara
  • Explore Hanoi’s rich heritage
  • Cruise Ha Long’s stunning waters
  • Discover Angkor Thom’s grandeur
  • Sail Mekong’s timeless villages
Activities
Wildlife Viewing, Hiking
Activity Level
Variable
Embark on a 16-day cruise aboard the MS Amadara, exploring Hanoi, Ha Long Bay, Siem Reap, and Ho Chi Minh City. Discover ancient temples, cruise the Mekong River, visit charming villages, and experience the vibrant blend of history and modern life in Vietnam and Cambodia.
Cruise Details
0
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