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Boat floating along the Mekong River

Top Mekong River Trips & Tours in April 2026

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Discover Mekong River in April 2026 on one of these 20 tours hand-selected by the travel experts at Adventure Life. Explore the best of during April 2026 as you enjoy Local Market Visits, Village Visits, Archaeological Site Visits, Biking, and Cooking Classes. Prices for trips in April 2026 range from $1,712 to $17,950 for a vacation of 5 to 16 days. Choose any of the below 20 itineraries in April 2026 and customize it when you contact one of Adventure Life's expert Mekong River trip planners.
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    • Mekong River
Royal Palace in Phnom Penh
from $2,071
EXPLORE

Mekong River - Upstream - Low water

Phnom Penh to Siem Reap - 5 Day Itinerary aboard The Jahan
Starts / Ends
Phnom Penh / Siem Reap
Activity Level
Variable
Join this 5-day Mekong River cruise from Phnom Penh to Siem Reap. Travel across the mighty Mekong delta to get an inside look at Cambodian culture. Stop in charming port towns and immerse yourself in the city's culture and history.
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit a local home in Kampong Cham
Cruise Details
0
Phnom Penh Royal Palace complex
from $1,825
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard The Jahan
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jahan. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.
  • Observed locals along the river
  • See the floating market in Cai Be
  • Visit Phnom Penh cultural sites
  • Visit Tan Chau floating fish farm
Cruise Details
0
Boat floating along the Mekong River
from $3,250
EXPLORE

Mekong River - Downstream - Low water

Siem Reap to Saigon - 8 Day Itinerary aboard Jayavarman
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Village Visits, Local Market Visits, Archaeological Site Visits
Activity Level
Variable
Embark on this 8-day Mekong River cruise from Siem Reap to Saigon during low water season and discover the wonders of the Mekong. Experience the diverse cultures of Vietnam and Cambodia as you navigate the mighty Mekong Delta. Pause at quaint port towns and fully engage with the local culture and history.
  • Interact with locals
  • Explore Cambodian culture
  • Observed locals along the river
  • Explore the Mekong River
  • Discover villages and markets
Cruise Details
0
Houses of Tonle Sap
from $1,951
EXPLORE

Mekong River - Upstream - Low water

Phnom Penh to Siem Reap - 5 Day Itinerary aboard Jayavarman
Starts / Ends
Phnom Penh / Siem Reap
Activity Level
Variable
Take this 5-day Low Water Mekong River cruise from Phnom Penh to Siem Reap aboard the Jayavarman. Travel across the mighty Mekong Delta to get an inside look at Cambodian culture. Stop in charming port towns and immerse yourself in the city's culture and history.
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit a local home in Kampong Cham
Cruise Details
0
Phnom Penh Royal Palace complex
from $1,712
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard Jayavarman
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jayavarman. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.
  • Observed locals along the river
  • See the floating market in Cai Be
  • Visit Phnom Penh cultural sites
  • Visit Tan Chau floating fish farm
Cruise Details
0
Royal Palace and Silver Pagoda
from $1,712
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard Jayavarman
Starts / Ends
Phnom Penh / Ho Chi Minh City
Activity Level
Variable
Cruise downstream on the Mekong River in majestic style aboard the Jayavarman on this 4-day journey from Phnom Penh to Saigon. Learn about the culture and heritage with visits to rural villages, historic pagodas, and colorful markets
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit Tan Chau floating fish farm
Cruise Details
0
Boy on wooden fishing boat
from $1,951
EXPLORE

Mekong River - Downstream - Low water

Siem Reap to Phnom Penh - 5 Day Itinerary aboard Jayavarman
Starts / Ends
Siem Reap / Phnom Penh
Activity Level
Variable
Embark on a 5-day cruise along the Mekong River from Siem Reap to Phnom Penh with the Jayavarman, and cruise the expansive Mekong Delta to discover the pre-Angkorian temples and culture of Cambodia.
  • Explore the mighty Mekong River
  • Discover pre-Angkorian temples
  • Explore Tonle's riverine
  • Learn about Phnom Penh
Cruise Details
0
Sunset over the Mekong River
from $3,620
EXPLORE

Mekong River - Downstream - Low water

Siem Reap to Saigon - 8 Day Itinerary aboard The Jahan
Starts / Ends
Siem Reap / My Tho
Activities
Cooking Classes
Activity Level
Variable
Enjoy an 8-day Mekong River cruise from Siem Reap to Saigon aboard the Jahan during the low water season. Discover Vietnam and Cambodia's southern cultures while exploring the Mekong Delta. Pause at port towns and immerse yourself in the region's culture and history.
  • Explore Kampong Cham
  • Discover Angkor Ban
  • Discover Binh Thanh Island
  • Experience Tan Chau
Cruise Details
0
Traditional mat-making
from $1,825
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard The Jahan
Starts / Ends
Phnom Penh / My Tho
Activities
Biking
Activity Level
Variable
On this 4-day journey from Phnom Penh to Saigon, cruise downstream on the lower Mekong River in majestic style aboard the Jahan. See the stunning scenery and discover the culture and history of the various towns along the mighty Mekong.
  • Experience Binh Thanh Island
  • Explore My An Hung Village
  • Discover Tan Chau
  • Experience Cao Dai
Cruise Details
0
The beautiful Vinh Trang temple near My Tho
from $3,250
EXPLORE

Mekong River - Upstream - Low water

Saigon to Siem Reap - 8 Day Itinerary aboard Jayavarman
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Explore the Mekong River in sumptuous luxury aboard the Jayavarman on this 8-day low-water river journey, which cruises majestically along the lower Mekong from Saigon to Siem Reap. Explore the mighty Mekong and learn about the culture and history of different towns along the river.
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Tan Chau floating fish farm
  • Visit Phnom Penh cultural sites
Cruise Details
0
Everyday life in Vietnam
from $2,849
EXPLORE

Charms of the Mekong - Cruise Only

Ho Chi Minh - Siem Reap - 8 Day Itinerary aboard MS Amadara
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Embark on an 8-day river cruise aboard the MS Amadara, starting in Ho Chi Minh City, a vibrant blend of history and modernity. Cruise the Mekong River, exploring villages, pagodas, and markets and experiencing local traditions, including a monk’s blessing and artisan crafts.
  • Explore Cai Be’s vibrant workshops
  • Discover Sa Dec history
  • Visit Phnom Penh landmarks
  • Experience Oknhatey, silk weaving
Cruise Details
0
The colorful Tonle Sap village
from $10,570
NO SS
EXPLORE

Mekong Expedition - Ho Chi Minh to Siem Reap (Extension)

Low water - 8 Day Itinerary aboard Aqua Mekong
Activity Level
Variable
From Ho Chi Minh, Vietnam to Phnom Penh, Cambodia, luxurious Aqua Mekong takes you on this 8-day Mekong River cruise, visiting Buddhist temples, local villages & markets, and touring Chau Doc, Kampong Chhnang, Kampong Tralach, Koh Oknha Tey, and Sa Dec.
  • Discover My An Hung
  • Enjoy a traditional performance
  • Learn to cook Mekong dishes
  • Visit Cambodia's National Museum
  • Past by Buddhist temples
Cruise Details
0
Kampong Chhnang
from $5,828
EXPLORE

Charms of the Mekong

16 Day Itinerary aboard MS Amadara
Starts / Ends
Ho Chi Minh City / Hanoi
Activities
Land & Sea Exploration
Activity Level
Variable
Embark on a 16-day cruise aboard the MS Amadara. Explore the Mekong, visit rural villages and ancient temples, and discover Angkor’s UNESCO sites in Siem Reap before concluding with an overnight stay at Ha Long Bay.
  • Explore Ho Chi Minh vibrant city
  • Visit Phnom Penh historic palaces
  • Discover Cai Be markets
  • Tour Siem Reap ancient temples
Cruise Details
0
Kampong Chhnang
from $2,849
EXPLORE

Riches of the Mekong - Cruise Only

8 Day Itinerary aboard MS Amadara
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Embark on an 8-day river cruise from Siem Reap to Ho Chi Minh aboard the MS Amadara, exploring rural villages, bustling markets, and historic sites. Experience Cambodia and Vietnam’s rich culture through artisan crafts, temple visits, and unique rides by oxcart, tuk-tuk, and trishaw.
  • Explore Angkor Ban village
  • Visit Oknhatey, Silk Island
  • Tour Phnom Penh highlights
  • Discover Oudong, royal capital
Cruise Details
0
Local moving cattle through the fields
from $5,828
EXPLORE

Riches of the Mekong

16 Day Itinerary aboard MS Amadara
Activities
Wildlife Viewing, Hiking
Activity Level
Variable
Embark on a 16-day cruise aboard the MS Amadara, exploring Hanoi, Ha Long Bay, Siem Reap, and Ho Chi Minh City. Discover ancient temples, cruise the Mekong River, visit charming villages, and experience the vibrant blend of history and modern life in Vietnam and Cambodia.
  • Explore Hanoi’s rich heritage
  • Cruise Ha Long’s stunning waters
  • Discover Angkor Thom’s grandeur
  • Sail Mekong’s timeless villages
Cruise Details
0
The floating village of Tonle Sap, Cambodia
from $6,400
NO SS
EXPLORE

Mekong Explorer - Ho Chi Minh to Siem Reap (Extension)

5 Day Itinerary aboard Aqua Mekong
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activities
Spa Relaxation
Activity Level
Variable
Board the Aqua Mekong in My Tho for a 5-day Mekong River cruise of Cambodia & Vietnam, including stops in Ho Chi Minh City, Phnom Penh, and Long Son Pagoda atop Sam Mountain. Travel back in time as you cruise upriver through the thriving Mekong Delta past floating villages, colonial vestiges, and gilded pagodas.
  • Enjoy a visit to a local's home
  • Walk through verdant plantations
  • Meet & interact with Buddhist Monks
Cruise Details
0
Phnom Penh Royal Palace complex
from $10,290
2for1
EXPLORE

Luxury Mekong

Siem Reap to Ho Chi Minh City - 8 Day Itinerary aboard Scenic Spirit
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Urban Exploration
Activity Level
Variable
Experience an 8-day cruise along the Mekong River from Siem Reap to Ho Chi Minh on the Scenic Spirit, blending cultural exploration with relaxation. Discover historical sites and local traditions while enjoying luxurious comfort and the region's vibrant contrasts.
  • Explore beauty of Angkor Ban
  • Visit architecture of Phnom Penh
  • Visit the Royal Palace
  • Sail through Vinh Te canal
Cruise Details
0
Explore the floating village of Tonle Sap
from $4,800
NO SS
EXPLORE

Mekong Discovery - Phnom Penh to Ho Chi Minh

4 Day Itinerary aboard Aqua Mekong
Activity Level
Variable
Embark the luxurious Aqua Mekong in Phnom Pehn, Cambodia on this 4-day discovery cruise along the Mekong River all the way to Ho Chi Minh City, Vietnam. You'll peruse vibrant markets and visit typical Mekong Delta villages while getting to know local cultures and ways of life, with a visit to Vinh Trang Pagoda and opportunities to bike along the way.
  • Walk through verdant plantations
  • Learn about local traditions
  • Visit Vinh Trang Pagoda
Cruise Details
0
1-18 of 20 Results

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