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Top Moselle River Trips & Tours in September 2025

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Discover Moselle River in September 2025 on one of these 10 tours hand-selected by the travel experts at Adventure Life. Explore the best of Cochem, Rudesheim, Trier, Bernkastel, and Amsterdam during September 2025 as you enjoy cruises, wine tasting, biking, hiking, and river cruises. Prices for trips in September 2025 range from $3,639 to $82,500 for a vacation of 7 to 15 days. Choose any of the below 10 itineraries in September 2025 and customize it when you contact one of Adventure Life's expert Moselle River trip planners.
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    • Moselle River
Heidelberg
$7,219
EXPLORE

Rhine & Moselle Delights

15 Day Itinerary aboard MS Amaprima
  • Cruise tranquil Lake Lucerne
  • Explore Strasbourg on foot
  • Visit Trier, Germany’s oldest city
  • Admire Amsterdam's beauty
Activities:
Biking, Hiking, Land & Sea Exploration, Wine Tasting
Activity Level:
Variable
Find inspiration along the castle-laden Rhine and its breathtaking tributary, the Moselle, on this unique 15-day cruise from Basel, located exactly between the corners of three countries—Germany, France and Switzerland. Cruise to Strasbourg, the “Crossroads of Europe,” and finally …
Cruise Details
0
Cochem town on the Mosel River, Germany
$10,725
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Classic Cruise – Germany & Luxembourg

7 Day Itinerary aboard La Nouvelle Etoile
  • Visit the 'Queen of German Castles'
  • Tour Germany’s oldest town
  • Finish the cruise in Luxembourg
  • Enjoy superb European wines
Activities:
Local Market Visits, River Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
Join an exciting and breathtaking 7-day cruise aboard La Nouvelle Etoile sailing through Germany & Luxembourg where you will find some of the historical places that will take you back in time. Visit Burg Eltz, the 12th Century Queen of German Castles. Tour Trier, Germany’s oldest town and …
Cruise Details
0
Explore historic Bamberg
$4,239
EXPLORE

Europe's Rivers & Castles - Cruise Only

Nuremberg - Luxembourg - 8 Day Itinerary aboard MS Amacerto
  • Explore Wurzburg’s Baroque splendor
  • Discover Bamberg’s architecture
  • Stroll Wertheim’s charming streets
  • Visit Rudesheim’s vineyard gondola
Starts / Ends:
Nuremberg / Luxembourg
Activities:
Archaeological Site Visits, Biking, Hiking, River Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
Embark on an 8-day river cruise aboard the MS Amacerto. Experience the charm of Europe, from the winding Main River to the UNESCO-listed Upper Middle Rhine Valley, lined with majestic castles and the lush, vineyard-covered hills of the Moselle. Delight in picturesque villages like Bernkastel, …
Cruise Details
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Cochem town on the Mosel River, Germany
$5,599
EXPLORE

The Rhine & Moselle (Northbound)

Basel - Amsterdam - 11 Day Itinerary aboard Avalon Imagery II
  • Explore Black Forest village
  • Visit Strasbourg's Gothic cathedral
  • Discover Heidelberg Castle ruins
  • Taste wine in Bernkastel
Starts / Ends:
Basel / Amsterdam
Activities:
River Cruises, Small Ship Cruises, Wine Tasting
Activity Level:
Variable
Embark on an 11-day cruise aboard the Avalon Imagery II. Cruise along the Rhine and Moselle Rivers, starting in Basel, Switzerland, and visiting remarkable cities in Germany, France, and Amsterdam. Explore Breisach, the gateway to Germany's enchanting Black Forest, then journey to Strasbourg to …
Cruise Details
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Trier
$4,939
EXPLORE

Rhine & Moselle Delights - Cruise Only

11 Day Itinerary aboard MS Amaprima
  • Explore “La Petite France”
  • Bike along the Rhine River
  • Discover Porta Nigra's secrets
  • Enjoy the fairytale town of Cochem
Starts / Ends:
Basel / Amsterdam
Activities:
Biking, Hiking, River Cruises, Wine Tasting
Activity Level:
Variable
Join the MS Amaprima on a exclusive cruise from Basel to Amsterdam. Fairytales come to life as you find inspiration along the castle-laden Rhine and its breathtaking tributary, the Moselle. From Basel, located exactly between the corners of three countries—Germany, France and …
Cruise Details
0
Cochem
$4,139
EXPLORE

Rhine & Moselle Splendors - Cruise Only

Luxembourg - Basel - 8 Day Itinerary aboard MS Amacerto
  • Explore Cochem’s historic castle
  • Cruise Rhine Gorge’s beauty
  • Visit Heidelberg's treasure
  • Taste Rudesheim’s unique coffee
Starts / Ends:
Luxembourg / Basel
Activities:
Biking, Hiking, Village Visits, Wine Tasting
Activity Level:
Variable
Embark on an 8-day river cruise aboard the MS Amacerto. Immerse yourself in the charm of fairytale villages—explore Trier, home to ancient Roman wonders, and enchanting Cochem, where history and folklore breathe life into every cobblestone street. Delight in whimsical fantasies at …
Cruise Details
0
Enjoy time in Dusseldorf
$5,954
EXPLORE

Vineyards of the Rhine & Moselle

13 Day Itinerary aboard MS Amaprima
  • Explore the Rhine River
  • Admire vibrant Amsterdam
  • Visit a local tavern in Cologne
  • Tour the stunning city of Paris
Starts / Ends:
Amsterdam / Paris
Activities:
Biking, Hiking, Land & Sea Exploration, Local Market Visits, Village Visits
Activity Level:
Variable
Drink in the beauty, history and flavor of the Rhine and Moselle river valleys’ iconic vineyards. Begin your journey with a gentle ride through Amsterdam’s legendary canals, then head to Cologne where you can whet your palate for the wines ahead by tasting Kolsch beer. As for the …
Cruise Details
0
Frauenkirche church in Nuremberg
$6,299
EXPLORE

Europe's Rivers & Castles

Prague - Paris - 14 Day Itinerary aboard MS Amaprima
  • Explore attractive Prague
  • Admire Nuremberg's Gothic churches
  • Visit the medieval city of Wertheim
  • Sail through the Rhine River gorge
Activities:
Biking, Hiking, Land & Sea Exploration, Wine Tasting
Activity Level:
Variable
Embark on a 14-day cruise with 3 nights in Prague and Paris aboard the MS Amaprima. Begin your journey in Prague and conclude in Paris, exploring three stunning rivers. Cruise the meandering Main, the castle-lined Rhine, and the vineyard-draped Moselle. Wander through storybook villages like …
Cruise Details
0
Visit charming towns on the Moselle River
$3,639
EXPLORE

Vineyards of the Rhine & Moselle - Cruise Only

8 Day Itinerary aboard MS Amaprima
  • Tour the romantic Amsterdam
  • Visit Cologne's cathedral
  • Visit Rudesheim's vineyards
  • Admire beautiful castles
Starts / Ends:
Amsterdam / Luxembourg
Activities:
Biking, Hiking, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Visit some of Europe's most fascinating cities as you sail the Rhine River from youthful Amsterdam to Germany's fashion center, Düsseldorf. Explore splendid Cologne with its magnificent dome and admire the picturesque Rhine castles on your way to bustling Frankfurt and medieval …
Cruise Details
0
La Nouvelle Etoile Cruising
$82,500
EXPLORE

Private Charter - Classic Cruise - Germany & Luxembourg Aboard La Nouvelle Etoile

7 Day Itinerary aboard La Nouvelle Etoile
  • Tour Germany’s oldest town
  • Enjoy superb European wines
  • Visit the 'Queen of German Castles'
  • Finish the cruise in Luxembourg
Activities:
Local Market Visits, River Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
The Mosel River traverses a deep valley through woodlands and vineyards in eastern Germany. This 7-day cruise on La Nouvelle Etoile allows barge enthusiasts to see two of the region's most famous attractions: castles and wines. Visit Burg Eltz, the 12th-century Queen of German Castles in …
Cruise Details
0
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