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Top Main River Trips & Tours in October 2026

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Discover Main River in October 2026 on one of these 12 tours hand-selected by the travel experts at Adventure Life. Explore the best of during October 2026 as you enjoy Village Visits, Archaeological Site Visits, Wine Tasting, Hiking, and Urban Exploration. Prices for trips in October 2026 range from $1,995 to $25,590 for a vacation of 7 to 15 days. Choose any of the below 12 itineraries in October 2026 and customize it when you contact one of Adventure Life's expert Main River trip planners.
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Explore historic Bamberg
from $4,449
$2500
EXPLORE

Europe's Rivers & Castles - Cruise Only

Nuremberg - Luxembourg - 8 Day Itinerary aboard MS Amacerto
  • Explore Wurzburg’s Baroque splendor
  • Discover Bamberg’s architecture
  • Stroll Wertheim’s charming streets
  • Visit Rudesheim’s vineyard gondola
Starts / Ends
Nuremberg / Luxembourg
Activities
Hiking
Activity Level
Variable
Set sail on an 8-day river cruise aboard the MS Amacerto, exploring Europe’s charm from the scenic Main River to the Upper Middle Rhine Valley's castles and Moselle's vineyards. Visit picturesque villages like Bernkastel, Cochem, and Rothenburg, admire the Wurzburg Residenz fresco, and savor German wines and smoked beer.
Cruise Details
0
Explore the old district of Frankfurt
from $2,626
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Cruise through the Heart of Europe from the Rhine to the Danube

Strasbourg to Vienna - 10 Day Itinerary aboard MS Beethoven
  • Enjoy Frankfurt’s skyline views
  • Discover Würzburg’s baroque beauty
  • Taste Nuremberg’s famous Lebkuchen
  • Explore Romantic Road gems
  • Discover Vienna’s imperial palaces
Starts / Ends
Strasbourg / Vienna
Activities
Small Ship Sailing
Activity Level
Variable
This 10-day voyage aboard the MS Beethoven brings you Europe’s cultural gems, from Frankfurt’s modern skyline to medieval towns like Rothenburg and Würzburg. Explore Regensburg’s 2,000-year-old history, savor Nuremberg’s famous Lebkuchen, and conclude in imperial Vienna with optional palace visits and a classical concert.
Cruise Details
0
Stop in Frankfurt, a major financial hub in Germany
from $2,709
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Along the Danube and the Rhine - Following the Romantic Road

Roundtrip Strasbourg - 10 Day Itinerary aboard MS Beethoven
  • Discover Vienna’s imperial splendor
  • Stroll Passau’s historic streets
  • See Regensburg’s ancient treasures
  • Enjoy Frankfurt skyline views
Starts / Ends
Strasbourg / Strasbourg
Activities
Local Market Visits
Activity Level
Variable
Sail the Danube and Rhine on a 10-day river cruise,, aboard MS Beethoven, discovering Europe’s most iconic cities and historic gems. Explore imperial Vienna, medieval Regensburg, and the Romantic Road’s charming towns before ending with modern Frankfurt’s dazzling skyline.
Cruise Details
0
River through Koblenz Germany
from $2,014
EXPLORE

The Valley of the romantic Rhine, the Moselle and the Main

Strasbourg Roundtrip - 7 Day Itinerary aboard MS Gérard Schmitter
  • Cruise Iffezheim & Gambsheim locks
  • Enjoy Strasbourg at night
  • Visit the unique Reichsburg Castle
  • Join an exclusive wine tasting
Activity Level
Variable
Explore the enchanting cities of Strasbourg, Frankfurt, Cochem, Koblenz, Rudesheim and Mannheim on this 7-day river cruise aboard the MS Gérard Schmitter. As you travel the Rhine, Moselle, and Main rivers, you'll have the chance to tour ancient towns, bike through verdant valleys, savor the local wines, and explore castles.
Cruise Details
0
Strasbourg at dusk
from $1,995
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The Valley of the Romantic Rhine, the Moselle and the Main

Strasbourg Roundtrip - 7 Day Itinerary aboard MS La Boheme
  • Enjoy Strasbourg at night
  • Visit Cochem, Pearl of the Moselle
  • See the unique Reichsburg Castle
  • Discover the famous Lorelei Rock
Starts / Ends
Strasbourg / Strasbourg
Activity Level
Variable
Discover three extraordinary rivers: the enchanting Rhine, the graceful Moselle, and the charming Main, on this incredible 7-day cruise aboard La Boheme exploring this romantic region. Delight yourself with the enchanting city of Frankfurt with its mix of ancient and modern sites that are sure to astonish you.
Cruise Details
0
Brilliant tulips growing near Amsterdam
from $12,190
2for1
EXPLORE

Splendours of Europe

Amsterdam - Budapest - 15 Day Itinerary aboard Emerald Sky
  • Discover Amsterdam’s canals
  • Explore Cologne’s Old Town
  • Admire castles along Rhine Gorge
  • Stroll Miltenberg’s medieval street
Starts / Ends
Amsterdam / Budapest
Activity Level
Variable
Join this 15-day Splendors of Europe cruise on the Emerald Sky from Amsterdam to Budapest. Cruise through the Netherlands, Germany, Austria, Slovakia, and Hungary. Experience stunning landscapes, medieval towns, and hikes to hilltop fortresses. Explore four capital cities, each providing a distinctive perspective on the region's rich history.
Cruise Details
0
Explore the inspiring Amsterdam
from $12,190
2for1
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Splendours of Europe

Amsterdam - Budapest - 15 Day Itinerary aboard Emerald Destiny
  • Explore Amsterdam’s canals
  • Admire Rhine Gorge’s castles
  • Wander Miltenberg’s cobbled lanes
  • Visit Wurzburg’s Baroque palace
Starts / Ends
Amsterdam / Budapest
Activity Level
Variable
Embark on the 15-day Splendours of Europe cruise aboard the Emerald Destiny, traveling from Amsterdam to Budapest. Discover the wonders of the Netherlands, Germany, Austria, Slovakia, and Hungary while indulging in a glass-top canal boat excursion in Amsterdam. Throughout the visit to four capital cities, immerse in rich history of the region.
Cruise Details
0
Ehrenfels Castle on Rhine River near Rudesheim
from $2,362
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5 Different Rivers: The Rhine, Neckar, Main, Moselle, and Saar (Port-to-port cruise)

Strasbourg to Luxembourg - 9 Day Itinerary aboard MS Leonardo Da Vinci
  • Enjoy Heidelberg Castle guided tour
  • Rudesheim vineyard wine tasting
  • Enjoy Rhine Valley scenic sailing
  • Explore Saarburg’s old town
Starts / Ends
Strasbourg / Remich
Activity Level
Variable
Set sail on a 9-day Rhine and Moselle river cruise from Strasbourg to Luxembourg aboard MS Leonardo Da Vinci. Discover Heidelberg Castle, Mainz Cathedral, and Trier’s Roman ruins. Explore Frankfurt, Rüdesheim’s vineyards, Cochem Castle, and Luxembourg’s historic city center. Enjoy wine tastings, guided tours, and unique cultural landmarks.
Cruise Details
0
Enjoy a quiet moment on the banks of the Danube
from $12,190
2for1
EXPLORE

Splendours of Europe

Budapest - Amsterdam - 15 Day Itinerary aboard Emerald Dawn
  • Explore Budapest’s grand landmarks
  • Discover Bratislava’s Old Town
  • Tour Vienna’s imperial highlights
  • Visit Melk Abbey’s ancient library
Starts / Ends
Budapest / Amsterdam
Activity Level
Variable
Embark on a 14-day river cruise on the Emerald Dawn, starting in Budapest and exploring cities like Vienna, Wurzburg, and Cologne along the Danube, Rhine, and Main rivers. Experience guided tours and unique cultural highlights, culminating in Amsterdam's vibrant atmosphere.
Cruise Details
0
Romantic evening light over Basel
from $5,496
Save $1500
EXPLORE

Reflections on the Rhine (Southbound)

Amsterdam to Basel - 10 Day Itinerary aboard Avalon Imagery II
  • Explore Amsterdam’s canals
  • Discover Nijmegen’s Roman ruins
  • Taste Rüdesheim wines
  • Visit Strasbourg’s La Petite France
Starts / Ends
Amsterdam / Basel
Activities
Wine Tasting, Village Visits, Urban Exploration, Archaeological Site Visits, Biking
Activity Level
Variable
Experience Europe’s Rhine River from Amsterdam to Basel for 10 days on Avalon Imagery II. Explore Amsterdam’s canals, Nijmegen’s Roman ruins, Cologne Cathedral, Rhine Gorge castles, Rüdesheim vineyards, Heidelberg Castle, Strasbourg’s La Petite France, and the Black Forest with guided tours, tastings, and scenic walks.
Cruise Details
0
Explore the unique architecture of Bamberg
from $6,999
EXPLORE

European Jewels

Budapest - Amsterdam - 15 Day Itinerary aboard River Duchess
  • Experience Frankfurt’s
  • Explore Nuremberg
  • Enjoy Rudesheim
  • Discover Vienna
Starts / Ends
Budapest / Amsterdam
Activity Level
Variable
Sail the Danube on a 15-day river cruise from Budapest to Amsterdam aboard the River Duchess. Explore historic cities, stunning landscapes, and cultural treasures with expert-guided tours, wine tastings, and local experiences.
Cruise Details
0
Explore the inspiring Amsterdam
from $5,299
EXPLORE

Grand European Tour: Budapest to Amsterdam

Budapest to Amsterdam - 15 Day Itinerary aboard Viking River Cruises
  • Discover Europe’s castles & culture
  • Visit St. Stephen’s Cathedral
  • See St. Peter’s Cathedral
  • Learn Wertheim's tradition
Starts / Ends
Budapest / Amsterdam
Activity Level
Variable
Join this 15-day Grand European Tour from Amsterdam to Budapest. Explore the beauty, nature, and architecture of Netherlands, Germany, Austria, and Hungary while sailing along the Danube, Main and Rhine Rivers.
Cruise Details
0
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