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Top Main River Trips & Tours in September 2026

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Discover Main River in September 2026 on one of these 7 tours hand-selected by the travel experts at Adventure Life. Explore the best of during September 2026 as you enjoy Village Visits, Wine Tasting, Archaeological Site Visits, Hiking, and Biking. Prices for trips in September 2026 range from $1,995 to $26,590 for a vacation of 7 to 15 days. Choose any of the below 7 itineraries in September 2026 and customize it when you contact one of Adventure Life's expert Main River trip planners.
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Explore historic Bamberg
from $4,849
CLP
EXPLORE

Europe's Rivers & Castles - Cruise Only

Nuremberg - Luxembourg - 8 Day Itinerary aboard MS Amacerto
Starts / Ends
Nuremberg / Luxembourg
Activities
Hiking, Wine Tasting, Village Visits, Biking, Archaeological Site Visits
Activity Level
Variable
Set sail on an 8-day river cruise aboard the MS Amacerto, exploring Europe’s charm from the scenic Main River to the Upper Middle Rhine Valley's castles and Moselle's vineyards. Visit picturesque villages like Bernkastel, Cochem, and Rothenburg, admire the Wurzburg Residenz fresco, and savor German wines and smoked beer.
  • Explore Wurzburg’s Baroque splendor
  • Discover Bamberg’s architecture
  • Stroll Wertheim’s charming streets
  • Visit Rudesheim’s vineyard gondola
Cruise Details
0
Strasbourg at dusk
from $1,995
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The Valley of the Romantic Rhine, the Moselle and the Main

Strasbourg Roundtrip - 7 Day Itinerary aboard MS La Boheme
Starts / Ends
Strasbourg / Strasbourg
Activity Level
Variable
Discover three extraordinary rivers: the enchanting Rhine, the graceful Moselle, and the charming Main, on this incredible 7-day cruise aboard La Boheme exploring this romantic region. Delight yourself with the enchanting city of Frankfurt with its mix of ancient and modern sites that are sure to astonish you.
  • Enjoy Strasbourg at night
  • Visit Cochem, Pearl of the Moselle
  • See the unique Reichsburg Castle
  • Discover the famous Lorelei Rock
Cruise Details
0
River through Koblenz Germany
from $2,348
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The Valley of the romantic Rhine, the Moselle and the Main

Strasbourg Roundtrip - 7 Day Itinerary aboard MS Gérard Schmitter
Activity Level
Variable
Explore the enchanting cities of Strasbourg, Frankfurt, Cochem, Koblenz, Rudesheim and Mannheim on this 7-day river cruise aboard the MS Gérard Schmitter. As you travel the Rhine, Moselle, and Main rivers, you'll have the chance to tour ancient towns, bike through verdant valleys, savor the local wines, and explore castles.
  • Cruise Iffezheim & Gambsheim locks
  • Enjoy Strasbourg at night
  • Visit the unique Reichsburg Castle
  • Join an exclusive wine tasting
Cruise Details
0
Brilliant tulips growing near Amsterdam
from $13,190
2for1
EXPLORE

Splendours of Europe

Amsterdam - Budapest - 15 Day Itinerary aboard Emerald Sky
Starts / Ends
Amsterdam / Budapest
Activities
Local Market Visits
Activity Level
Variable
Join this 15-day Splendors of Europe cruise on the Emerald Sky from Amsterdam to Budapest. Cruise through the Netherlands, Germany, Austria, Slovakia, and Hungary. Experience stunning landscapes, medieval towns, and hikes to hilltop fortresses. Explore four capital cities, each providing a distinctive perspective on the region's rich history.
  • Discover Amsterdam’s canals
  • Explore Cologne’s Old Town
  • Admire castles along Rhine Gorge
  • Stroll Miltenberg’s medieval street
Cruise Details
0
Explore the inspiring Amsterdam
from $13,190
2for1
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Splendours of Europe

Amsterdam - Budapest - 15 Day Itinerary aboard Emerald Destiny
Starts / Ends
Amsterdam / Budapest
Activity Level
Variable
Embark on the 15-day Splendours of Europe cruise aboard the Emerald Destiny, traveling from Amsterdam to Budapest. Discover the wonders of the Netherlands, Germany, Austria, Slovakia, and Hungary while indulging in a glass-top canal boat excursion in Amsterdam. Throughout the visit to four capital cities, immerse in rich history of the region.
  • Explore Amsterdam’s canals
  • Admire Rhine Gorge’s castles
  • Wander Miltenberg’s cobbled lanes
  • Visit Wurzburg’s Baroque palace
Cruise Details
0
Explore the unique architecture of Bamberg
from $7,999
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European Jewels

Budapest - Amsterdam - 15 Day Itinerary aboard River Duchess
Starts / Ends
Budapest / Amsterdam
Activity Level
Variable
Sail the Danube on a 15-day river cruise from Budapest to Amsterdam aboard the River Duchess. Explore historic cities, stunning landscapes, and cultural treasures with expert-guided tours, wine tastings, and local experiences.
  • Experience Frankfurt’s
  • Explore Nuremberg
  • Enjoy Rudesheim
  • Discover Vienna
Cruise Details
0
Explore the inspiring Amsterdam
from $5,799
EXPLORE

Grand European Tour: Budapest to Amsterdam

15 Day Itinerary aboard Viking River Cruises
Starts / Ends
Budapest / Amsterdam
Activities
Urban Exploration
Activity Level
Variable
Join this 15-day Grand European Tour from Amsterdam to Budapest. Explore the beauty, nature, and architecture of Netherlands, Germany, Austria, and Hungary while sailing along the Danube, Main and Rhine Rivers.
  • View the Benedictine monastery
  • Visit St. Stephen’s Cathedral
  • See St. Peter’s Cathedral
  • Learn Wertheim's tradition
Cruise Details
0
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