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As your luxury boat sails across the azure waters of Europe's southern seas bask in the warm Mediterranean sun and take in the stunning views of the region’s most iconic Mediterranean cruise ports. Depending on the itinerary, voyages may include stops in the vibrant seaside cities of Spain and France, as well as Italy's  famed Mediterranean ports like Venice, known as the "City of Bridges."  Travelers can also take advantage of Adventure Life's exclusive trips in the eastern Mediterranean, including Croatia and the Dalmatian Coast, as well as ancient Greek cities and other locations along the warm Adriatic Sea shores. The most popular things to do in the Mediterranean in 2025 are Archaeological Site Visits, Village Visits, Small Ship Sailing, Local Market Visits, and Wine Tasting. Our Mediterranean cruises in 2025 range in price from $958 to $112,500 for journeys of 5 to 29 days. We can help you choose the right Mediterranean cruise, no matter where you're going.
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    • Mediterranean
Beautiful Taormina, Italy, with Mt. Etna in the background
from $31,340
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Islands of the Mediterranean

Piraeus - Malaga - 12 Day Itinerary aboard Scenic Eclipse II
  • Explore Athens’ Acropolis
  • Discover Mykonos’ iconic windmills
  • Wander Santorini’s streets
  • Experience Chania’s Venetian harbor
Starts / Ends
Piraeus / Malaga
Activities
Local Market Visits, Village Visits, Archaeological Site Visits
Activity Level
Variable
Embark on a 12-day Mediterranean cruise aboard the Scenic Eclipse II, exploring iconic Greek islands like Mykonos and Santorini, along with the charming coastal towns of Sardinia and Ibiza. This journey combines rich cultural immersion, stunning scenery, and regional flavors across Southern Europe.
Cruise Details
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Cannes at sunset
from $23,590
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Splendors of Sicily, Italy and the French Riviera

Valletta - Nice - 9 Day Itinerary aboard Scenic Eclipse II
  • Explore Valletta’s walled city
  • Discover Taormina’s ancient theater
  • Admire Sorrento’s cliffside villas
  • Visit Civitavecchia iconic monument
Starts / Ends
Valletta / Nice
Activity Level
Variable
Embark on a 9-day Mediterranean cruise on the Scenic Eclipse II, starting in Valletta, Malta, and visiting stunning locations like Taormina, Sorrento, and Portofino. Experience the charm of Bastia, Monte Carlo, and Cannes, culminating in the beautiful Cote d’Azur in Nice.
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Stop in beautiful Malta
from $23,540
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Island Odyssey: Malta, Sicily & the Greek Isles

Valletta - Piraeus - 8 Day Itinerary aboard Scenic Eclipse II
  • Explore Valletta’s walled city
  • Discover Syracuse’s Greek ruins
  • Wander Monemvasia’s medieval street
  • Stroll Nafplion’s Old Town
Starts / Ends
Valletta / Piraeus
Activities
Wildlife Viewing
Activity Level
Variable
Embark on an 8-day cruise aboard Scenic Eclipse II, starting in Valletta, Malta, and visiting historic Syracuse, Nafplion, and Mykonos. Experience the cultural richness, history, and stunning coastal beauty of the Mediterranean in style and comfort.
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Charming streets of Mykonos, Greece
from $14,495
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Cruising the Greek Isles

Roundtrip Athens - 10 Day Itinerary aboard Le Dumont-d'Urville
  • Explore ancient Greek ruins
  • Visit Crete's Knossos Palace
  • Experience Santorini wine and hike
  • Wander in Patmos villages
Starts / Ends
Athens / Athens
Activities
Urban Exploration, Wine Tasting, Cooking Classes
Activity Level
Variable
Sail through Greece on a 12-day luxury cruise aboard Le Dumont d’Urville, from ancient Athens to sun-soaked islands like Santorini, Mykonos, and Patmos. Explore iconic ruins, whitewashed villages, and hidden gems with guided tours, hands-on culinary experiences, and exclusive cultural encounters that reveal the true heart of the Greek Isles.
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Enjoy the beauty of the Mediterranean
from $12,790
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Hidden Gems of the Croatian Riviera

Dubrovnik - Venice - 8 Day Itinerary aboard Emerald Kaia
  • Stroll Piran Venetian architecture
  • Admire Opatija coastal views
  • Visit Split’s UNESCO-listed palace
  • Sail Venice's iconic canals
Starts / Ends
Dubrovnik / Venice
Activity Level
Variable
8-day cruise along the Adriatic aboard Emerald Kaia. Explore the coastlines and islands of Greece, Turkey, Croatia, Italy, France and Spain. Discover rich history, charming streets, and breathtaking landscapes on your unique cruise
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A stunning fortified old town with massive stone walls overlooking the Adriatic Sea
from $12,495
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Adriatic Voyage: Croatia, Montenegro and Greece

Split to Athens - 9 Day Itinerary aboard Le Dumont-d'Urville
  • Explore ancient Split ruins
  • Cruise scenic Kotor Bay
  • Visit underground lake Cephalonia
  • Transit historic Corinth Canal
Starts / Ends
Venice / Athens
Activities
Kayaking, Biking
Activity Level
Variable
Sail from Venice to Athens on a 9-day Adriatic voyage aboard Le Dumont d’Urville. Explore ancient ruins, charming coastal towns, and scenic islands, with plenty of enriching excursions and unforgettable views.
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Explore colorful villages on Rhodes
from $11,990
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Greek Islands & Turkish Coastline

Roundtrip Athens - 8 Day Itinerary aboard Emerald Azzurra
  • Explore Athens' sophistication
  • Discover Delos' mythological past
  • Experience Mykonos' whitewashed
  • Visit Patmos’ sacred cave
Starts / Ends
Athens / Athens
Activity Level
Variable
Set sail on an 8-day cruise from Athens aboard the Emerald Azzurra, discovering Greece and Turkey's coastal gems. Experience ancient sites like Delos and Mykonos, enjoy leisure in Santorini, and explore local markets, all while relaxing on your luxurious yacht.
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Stop in beautiful Parga
from $16,840
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Mediterranean Enchantment

Athens - Dubrovnik - 8 Day Itinerary aboard Emerald Azzurra
  • Navigate Corinth Canal
  • Explore Delphi ruins
  • Discover Lefkada coastlines
  • Experience Parga’s castle views
Starts / Ends
Athens / Dubrovnik
Activities
Hiking
Activity Level
Variable
Set sail on an 8-day cruise from Athens to Dubrovnik aboard the Emerald Azzurra. Explore historic sites like Delphi and enjoy scenic coastal stops, culminating in the medieval beauty of Dubrovnik.
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Explore colorful villages on Rhodes
from $11,990
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Classical Greece

Roundtrip Athens - 8 Day Itinerary aboard Emerald Azzurra
  • Explore Delos archaeological island
  • Wander Mykonos whitewashed island
  • Visit Bodrum seaport
  • Discover Rhodes old town
Starts / Ends
Athens / Athens
Activity Level
Variable
Embark on an 8-day cruise aboard the Emerald Azzurra from Athens, exploring Delos, Bodrum, Rhodes, Santorini, Chania, and Hydra. Discover ancient ruins, stunning landscapes, and charming harbors before returning to the historic Greek capital.
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Wander through Rome
from $11,790
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Enchanting Italian Coastlines

Roundtrip Civitavecchia - 8 Day Itinerary aboard Emerald Sakara
  • Explore Amalfi's dramatic cliffs
  • Wander Capri's chic lanes
  • Uncover Sorrento’s cliffside villas
  • Enjoy Capri’s seafood cuisine
Starts / Ends
Civitavecchia / Civitavecchia
Activity Level
Variable
Experience the thrill of spectacular adventures along the enchanting coastlines and captivating islands of Greece, Turkey, Croatia, Italy, France, and Spain on an unforgettable 8-day cruise aboard the luxurious Emerald Sakara.
Cruise Details
0
St.Blaise Church, Dubrovnik
from $12,220
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Croatia, Under Sail Aboard Le Ponant

Dubrovnik - Dubrovnik - 8 Day Itinerary aboard Le Ponant
  • See private performance of Moreška
  • Explore the Mljet Island
  • Wander through Dubrovnik
  • Sail to the monumental Bay of Kotor
Starts / Ends
Dubrovnik / Dubrovnik
Activity Level
Variable
Set sail on an 8-day cruise to Croatia, Under Sail aboard Le Ponant roundtrip Dubrovnik. Explore Mljet Island, Korcula, Komiza, Hvar, Pučišća, Šipan, and the picturesque port of Kotor in Montenegro.
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The medieval fortress of Calvi
from $12,220
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Corsican shores, under Sail Aboard Le Ponant

Roundtrip Nice - 8 Day Itinerary aboard Le Ponant
  • Visit Balagne and Cap Corse
  • Visit Gulf of Ajaccio
  • Discover the Gulf of Sant’Amanza
  • Visit the Gulf of Roccapina
Starts / Ends
Nice / Nice
Activities
Scuba Diving, Snorkeling
Activity Level
Variable
Set sail on an 8-day cruise along the Corsican coastline aboard Le Ponant, departing from Nice. Explore the northern terrain of Balagne and Cap Corse with historic citadels and unspoiled villages. Experience the Gulf of Sant’Amanza. Visit the Gulf of Roccapina and Domaine de Murtoli before returning to Nice.
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Visit the Baroque Cathedral of Syracuse
from $8,220
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Cruising Southern Italy and Sicily – with Smithsonian Journeys

Valletta - Livorno - 9 Day Itinerary aboard Le Dumont-d'Urville
  • Explore Valletta's heritage
  • Discover Syracuse's history
  • Admire Taormina's scenic views
  • Experience Naples culture
Starts / Ends
Valletta / Livorno
Activity Level
Variable
Sail on this 9-day Southern Italy and Sicily cruise with Smithsonian Journeys aboard Le Dumont-d'Urville. Start in Valletta, Malta, exploring historic landmarks. Visit Syracuse's Greek and cultural sites and Taormina's scenic views and theater. Explore Reggio di Calabria's coast and museum. Visit Civitavecchia, and conclude in Livorno, Tuscany.
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Tour the charming city of Valletta, Malta.
from $9,450
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A Circumnavigation of Sicily with Smithsonian Journeys

Valletta - Valletta - 9 Day Itinerary aboard Le Bougainville
  • Take a loop around Sicily
  • Discover Sicily's beautiful cities
  • Visit Syracuse
  • Explore Palermo
Starts / Ends
Valletta / Valletta
Activity Level
Variable
During this 9-day cruise around Sicily aboard the new luxury expedition ship Le Bougainville, you'll be able to explore mythical places at the crossroads of Eastern and Western civilizations. Discover Sicily's most beautiful historic cities and ancient sites.
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Explore ancient monasteries in Greece
from $15,815
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The Hidden Pearls of the Aegean Sea

Athens to Athens - 10 Day Itinerary aboard Sea Cloud
  • Explore Athens' iconic landmarks
  • Sail to picturesque Nauplio
  • See Monemvasia's medieval allure
  • Discover Milos' unique landscape
Starts / Ends
Piraeus / Piraeus
Activity Level
Variable
Embark on a 10-day Greek cruise aboard Sea Cloud, starting in Athens and exploring iconic landmarks like the Parthenon. Sail to Nauplio, Monemvasia, Milos, Astypalaia, and Patmos, before concluding your journey in Ermoupoli, Syros' captivating capital.
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Colorful local boats in Greece
from $8,280
EXPLORE

A Symphony at Sea: The Musical Traditions of Greece

Roundtrip Athens - 8 Day Itinerary aboard Le Champlain
  • Explore historic Athens landmarks
  • Marvel at Delos ruins
  • Enjoy Mykonos’ seaside charm
  • Relax in car-free Hydra
Starts / Ends
Athens / Athens
Activities
Small Ship Sailing
Activity Level
Variable
Set sail on Le Champlain for an 8-day round-trip Mediterranean Cruise from Athens through the Greek Islands. Explore Heraklion, Santorini, Rhodes, Amorgos, Delos, Mykonos, and Hydra. Discover ancient ruins, scenic landscapes, and charming whitewashed villages. Each destination reveals a unique part of Greece’s history, culture, and beauty.
Cruise Details
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Visit beautiful Hydra
from $10,390
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Ancient Wonders of the Mediterranean

Athens - Valletta - 13 Day Itinerary aboard Le Dumont-d'Urville
  • Explore the rocky plateau of Athens
  • Explore Patmos
  • Admire volcanic beauty and ruins
  • Explore the Delphi Sanctuary
Starts / Ends
Athens / Valletta
Activity Level
Variable
Embark on a 13-day Mediterranean cruise aboard Le Dumont-d'Urville, exploring the enchanting destinations of Greece, Turkey, and Italy. Each destination offers unique experiences, from ancient ruins and historic monasteries to stunning beaches and charming villages.
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Scenic panoramic view of historic Perast on the Bay of Kotor
from $15,796
EXPLORE

Under Sail: Greece and the Dalmatian Coast

11 Day Itinerary aboard Sea Cloud
  • Sail a tall ship in historic waters
  • Tour ruins in Greece and Albania
  • Skim Montenegro’s Gulf of Kotor
  • Spend a day in Dubrovnik's Old Town
Activity Level
Variable
Spend 11 days immersed in the history & culture of the Mediterranean as you cruise aboard the Sea Cloud. Experience the crystal blue waters of the Aegean, Ionian, and Adriatic Seas as you visit Greece, Albania, Montenegro, and Croatia, home to historic sites and surprising beauty, like hiking or strolling in Dubrovnik, Ithaca, Korcula, and Hvar.
Cruise Details
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