Cruises Operated by American Cruise Lines, Inc.

Experience a 9-day cruise aboard American Symphony from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.

Join this 9-day Northeast Harbors cruise from Boston to New York aboard American Glory. Explore historic Boston before visiting picturesque Plymouth, MA, and the grandeur of Newport. Dive into maritime history in New London, Mystic, and Essex, CT. Lastly, enjoy an evening cruise around New York Harbor.

Embark on a 9-day cruise aboard American Jazz, navigating the Columbia & Snake Rivers. Cruise past Mount Hood and Mount St. Helens, reliving the golden age of riverboats. Explore Astoria's Victorian charm and visit Fort Clatsop. Journey through history in The Dalles, Richland, and Pendleton, culminating in the majestic landscapes of Hells Canyon.

Explore the Upper Mississippi River on this 9-day cruise from St. Louis to Minneapolis aboard the American Melody. Begin in St. Louis, Missouri, and travel through Alton, Hannibal, Muscatine, Dubuque, Winona, and Red Wing. Visit Mark Twain's boyhood home, explore historic towns, and marvel at the diverse landscapes.

Explore the segment of the Mississippi River on this 9-day cruise from St. Louis to Minneapolis American Symphony. Begin in St. Louis, Missouri, and through Alton, Hannibal, Muscatine, Dubuque, Winona, and Red Wing. Visit Mark Twain's boyhood home, explore historic towns, and marvel at the diverse landscapes.

Experience a 9-day cruise aboard American Splendor from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.

Embark on an unforgettable 9-day Columbia & Snake Rivers cruise aboard American Jazz. Experience scenic landscapes, historic towns, and diverse wildlife. Highlights include traveling through Hells Canyon, Columbia River Gorge, and Mount St. Helens.

Set sail on a 9-day Tennessee Rivers Cruise from Nashville to Chattanooga aboard American Symphony. Relax with expert talks, regional cuisine, and comfortable accommodation while exploring the history, culture, and natural beauty of America’s heartland.

Embark on a 9-day cruise from Chattanooga to Nashville aboard the American Symphony. Cruise the Tennessee River, visiting historic towns like Decatur, Florence, Savannah, and Paducah. Experience cultural landmarks, scenic landscapes, and enriching excursions that highlight the region's rich heritage.

Cruise the southeastern coast on a 9-day voyage from Charleston, South Carolina to Amelia Island, Florida, aboard American Liberty. Explore Savannah, Beaufort, Hilton Head, and more.

Cruise the Chesapeake Bay on a 9-day cruise aboard American Independence, sailing from Baltimore to Yorktown, Williamsburg, St. Michaels, and Annapolis. Explore colonial streets, museums, battlefields, maritime towns, wildlife-rich waterways, and historic harbors through guided tours and scenic cruising.

Sail from Washington to Baltimore on an 9-day cruise aboard American Independence. Explore Revolutionary War sites, historic seaports, and Chesapeake Bay wildlife. Visit Yorktown, Williamsburg, Cambridge, St. Michaels, and Annapolis. Enjoy onboard enrichment, local excursions, and scenic cruising through America’s historic heartland.