Cruises Operated by American Cruise Lines, Inc.

Explore New Orleans to Huntsville on a 16-day Mississippi River cruise aboard American Heritage. Visit historic estates, Civil War sites, music landmarks, museums, arts districts, and river towns while following the Mississippi and Tennessee rivers through Louisiana, Mississippi, Tennessee, Kentucky, and Alabama. Experience local traditions.

Explore a 16-day river cruise from Huntsville to New Orleans aboard American Heritage, following the Tennessee and Mississippi Rivers through Florence, Savannah, Paducah, Memphis, Vicksburg, Natchez, St. Francisville, Baton Rouge and Oak Alley, with historic sites, museums, music, Civil War history and Southern culture and historic cultural sites.

Sail the Mississippi River from St. Paul to New Orleans on a 16-day cruise aboard American Melody. Visit La Crosse, Dubuque, Davenport, Hannibal, St. Louis, Memphis, Vicksburg, Natchez, and Baton Rouge while exploring river history, Native heritage, Civil War sites, music, architecture, museums, agriculture, and regional culture.

Explore a 16-day Mississippi and Ohio River cruise from St. Louis to Pittsburgh aboard American Melody. Visit Paducah, Henderson, Evansville, Louisville, Madison, Cincinnati, Maysville, and Marietta, with time for museums, historic districts, Underground Railroad sites, regional art, river heritage, and American history. Discover local history.

Embark on a 16-day cruise linking two rivers, the Mississippi and Cumberland, between New Orleans and Nashville aboard American Symphony. Visit Civil War battlefields, antebellum estates, and the birthplaces of jazz, blues, and country music.

Experience a 15-day journey from Tacoma to Tacoma aboard American Constellation, exploring Mount Rainier, Olympic National Park, San Juan Islands, Victoria, and Puget Sound. Discover local landscapes, Indigenous heritage, maritime history, wildlife, and coastal communities through guided hikes, museum visits, scenic drives, and cultural excursions.

Experience a 15-day journey from Tacoma to Tacoma aboard American Constitution, exploring Mount Rainier, Olympic National Park, San Juan Islands, Victoria, and Puget Sound. Discover local landscapes, Indigenous heritage, maritime history, wildlife, and coastal communities through guided hikes, museum visits, scenic drives, and cultural excursions.

Explore Ketchikan, Misty Fjords, Wrangell, Petersburg, Glacier Bay, Sitka, Haines and Juneau on a 12-day Alaska cruise aboard American Constellation from Ketchikan to Juneau. Experience Alaska’s coastal landscapes, Indigenous cultures, Gold Rush history, working fishing towns and protected wilderness areas along the Inside Passage.

Set sail on a 10-day cruise on the Ohio River aboard American Symphony, sailing Louisville to Pittsburgh with stops in Madison, Cincinnati, and Marietta. Between days of scenic cruising, explore bourbon country, Underground Railroad history, and riverbank wildlife.

Set sail on a 10-day river cruise from Pittsburgh to Louisville aboard American Symphony, tracing the Ohio River through Wheeling, Marietta, Cincinnati and Madison. See steel-era history, ancient earthworks, and bourbon country.

Experience a 9-day cruise aboard American Symphony from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.

Join this 9-day Northeast Harbors cruise from Boston to New York aboard American Glory. Explore historic Boston before visiting picturesque Plymouth, MA, and the grandeur of Newport. Dive into maritime history in New London, Mystic, and Essex, CT. Lastly, enjoy an evening cruise around New York Harbor.