Cruises Operated by American Cruise Lines, Inc.

Travel from Memphis to Nashville on a 9-day river cruise aboard American Symphony. Enjoy live onboard music, explore cities like Paducah and Clarksville, and visit landmarks such as Fort Donelson and the Grand Ole Opry. Experience music, history, and river scenery through curated excursions and onboard activities.

Embark on a 16-day Mississippi River cruise from Minnesota to Louisiana aboard American Serenade, exploring St. Paul to New Orleans with stops in La Crosse, Dubuque, Davenport, Hannibal, St. Louis, Memphis, Vicksburg, and Natchez. Enjoy onboard activities, stunning scenery, and experiences like the Mark Twain Boyhood Home and more.

Experience a 9-day cruise aboard American Heritage from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.

Discover national parks and legendary rivers on a 16-day land and river cruise from Portland to Jackson. Cruise the Columbia and Snake Rivers, visit Astoria and The Dalles, see Mount St. Helens, and explore Hells Canyon. Continue to Glacier, Yellowstone, and Grand Teton National Parks with guided tours, meals, and select stays.

Embark on a 9-day Ohio River cruise from Pittsburgh to Louisville aboard American Melody. Explore Wheeling, Marietta, Cincinnati, Madison, and more. Discover historic architecture, museums, riverfront views, and cultural attractions while enjoying onboard activities, local cuisine, and scenic river landscapes.

Embark on an 9-day Cape Cod cruise aboard American Glory, round-trip from Boston. Visit Provincetown, Plymouth, Martha’s Vineyard, Newport, and New Bedford. Step into colonial history, maritime culture, and coastal scenery.

Experience Alaska on a comprehensive 19-day land and cruise journey aboard American Constellation. Travel through Fairbanks, Denali, Anchorage, Seward, Juneau, Glacier Bay, Sitka, Petersburg, Wrangell, and Frederick Sound. Explore national parks, encounter wildlife, and join guided cultural tours across Alaska’s most iconic landscapes.

Embark a 16-day Alaska land and sea journey from Fairbanks to Juneau aboard American Constitution. Explore Denali, Kenai Fjords, Glacier Bay, Haines, Petersburg, Wrangell, and Endicott Arm. Ride a dome train, watch whales and glaciers, and enjoy expert-led excursions with rare access to protected waters.

Sail from Pittsburgh to St. Louis on a 16-day Ohio River cruise aboard American Melody. Visit historic towns like Marietta, Cincinnati, Louisville, and Paducah. Discover museums, landmark sites, and cultural excursions while enjoying daily enrichment programs and scenic cruising.

Embark on a 16-day combined Columbia and Snake Rivers cruise aboard American Jazz and land tour through iconic national parks, Glacier, Yellowstone, and Grand Teton National Parks. Explore vibrant towns, hike scenic trails, visit historic landmarks, and enjoy wine tastings, nature tours, and enriching excursions.

Embark on a 16-day East Coast Inland Passage cruise aboard American Liberty. Explore coastal towns like Charleston, Savannah, and Beaufort. Enjoy guided excursions to historic sites, maritime museums, and Civil War landmarks. Discover lighthouses, plantations, and preserved Southern architecture across 14 ports along the East Coast.

Embark on a 12-day cruise aboard the American Constellation, departing and returning to Juneau. Explore historical sites, stunning scenery, and lively ports in Southern Alaska and the Inside Passage, including Glacier Bay, Endicott Arm, and Dawes Glacier, cultural excursions, and outdoor adventures.