Cruises Operated by American Cruise Lines, Inc.

Travel from Memphis to Nashville on a 9-day river cruise aboard American Symphony. Enjoy live onboard music, explore cities like Paducah and Clarksville, and visit landmarks such as Fort Donelson and the Grand Ole Opry. Experience music, history, and river scenery through curated excursions and onboard activities.

Cruise the Mississippi River on a 16-day voyage aboard American Serenade. Visit La Crosse, Dubuque, Davenport, Hannibal, St. Louis, Memphis, Tunica, Vicksburg, Natchez, and Baton Rouge while exploring museums, riverfronts, historic landmarks, Civil War sites, and music destinations. Enjoy scenic cruising through the Upper and Lower Mississippi.

Embark on a 9-day cruise aboard American Heritage from Memphis to New Orleans along the Lower Mississippi River. Visit Cleveland, Vicksburg, Natchez, Baton Rouge, and Oak Alley. Explore Civil War landmarks, historic homes, museums, plantations, and Louisiana wetlands while discovering the history, music, and culture of the American South.

Discover national parks and legendary rivers on a 16-day land and river cruise from Portland to Jackson. Cruise the Columbia and Snake Rivers, visit Astoria and The Dalles, see Mount St. Helens, and explore Hells Canyon. Continue to Glacier, Yellowstone, and Grand Teton National Parks with guided tours, meals, and select stays.

Embark on a 9-day cruise aboard American Song, navigating the Columbia & Snake Rivers. Cruise past Mount Hood, reliving the golden age of riverboats. Explore Astoria's Victorian charm and visit Fort Clatsop. Journey through history in The Dalles, Richland, and Pendleton, culminating in the majestic landscapes of Hells Canyon.

Embark on a 9-day Ohio River cruise from Pittsburgh to Louisville aboard American Melody. Explore Wheeling, Marietta, Cincinnati, Madison, and more. Discover historic architecture, museums, riverfront views, and cultural attractions while enjoying onboard activities, local cuisine, and scenic river landscapes.

Set sail for 9 days aboard American Serenade from St. Paul to St. Louis. Walk through historic Summit Avenue, admire La Crosse from Grandad’s Bluff, explore Dubuque’s River Museum, and discover Mark Twain’s legacy in Hannibal. Experience curated onboard programs, live music, and the beauty of the Upper Mississippi’s diverse wildlife.

Embark a 16-day Alaska land and sea journey from Fairbanks to Juneau aboard American Constitution. Explore Denali, Kenai Fjords, Glacier Bay, Haines, Petersburg, Wrangell, and Endicott Arm. Ride a dome train, watch whales and glaciers, and enjoy expert-led excursions with rare access to protected waters.

Sail from Pittsburgh to St. Louis on a 16-day Ohio River cruise aboard American Melody. Visit historic towns like Marietta, Cincinnati, Louisville, and Paducah. Discover museums, landmark sites, and cultural excursions while enjoying daily enrichment programs and scenic cruising.

Embark on a 16-day combined Columbia and Snake Rivers cruise aboard American Jazz and land tour through iconic national parks, Glacier, Yellowstone, and Grand Teton National Parks. Explore vibrant towns, hike scenic trails, visit historic landmarks, and enjoy wine tastings, nature tours, and enriching excursions.

Embark on a 16-day East Coast Inland Passage cruise aboard American Liberty. Explore coastal towns like Charleston, Savannah, and Beaufort. Enjoy guided excursions to historic sites, maritime museums, and Civil War landmarks. Discover lighthouses, plantations, and preserved Southern architecture across 14 ports along the East Coast.

Embark on a 12-day Alaskan Explorer cruise aboard the American Constitution, taking in Alaska’s untouched landscapes. The adventure begins and ends in Juneau, with stops in Haines, Glacier Bay, Sitka, Petersburg, Wrangell, and Dawes Glacier.