Have questions? We're here.
What a view.

Top South America Tours & Cruises in 2028

Travel made your way ™
Talk with an expert
Build your ideal South America trip. Call 800.344.6118
Start Planning My Trip
Filter (550 Results)
  • Start Date
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • South America
View of the wildlife in Torres del Paine
from $3,000
EXPLORE

Kaweskar Route

Puerto Natales Roundtrip - 5 Day Itinerary aboard MV Skorpios III
  • Observe Amalia Glacier
  • Sail across the ice at Calvo Fjord
  • Walk in a small native forest
  • Cruise along White Angostura Island
Starts / Ends
Puerto Natales / Puerto Natales
Activity Level
Variable
Sail along the Kaweskar Route during this 5-day small ship cruise from Puerto Natales through the Magellanic fjords and channels of Chilean Patagonia. Enjoy daily land explorations on the Amalia, El Brujo, Bernal, and Alsina Glaciers and the area of Fiordo Calvo.
Cruise Details
0
Red scarlet macaw in flight
from $2,727
EXPLORE

Rio de Janeiro and Amazon Clipper Cruise

8 Day Itinerary
  • Enjoy views of Rio de Janeiro
  • Visit Christ the Redeemer
  • Learn about local flora and fauna
  • Canoe along the Rio Negro
Starts / Ends
Rio de Janeiro / Manaus
Activities
Land & Sea Exploration
Activity Level
Relaxed
Rio de Janeiro and Amazon Clipper Cruise is a Brazil tour itinerary offered through Adventure Life. Review the day-by-day highlights and what's included, or contact a trip planner to customize the itinerary to your travel dates and interests.
Tour Details
0
Whale watching on Peninsula Valdes
from $600
EXPLORE

Peninsula Valdes Self-Drive

4 Day Itinerary
Activity Level
Relaxed
Tour Details
0
Penguin jump in Antarctica
from $13,495
Save 15%
EXPLORE

Complete Antarctica: Sail In, Fly Out

Ushuaia - Punta Arenas - 11 Day Itinerary aboard Ocean Nova
  • Cross Drake Passage route
  • Explore Antarctic Peninsula landing
  • Visit South Shetland Islands
  • Explore Estancia Olga Teresa
Starts / Ends
Ushuaia / Punta Arenas
Activities
Wildlife Viewing, Whale Watching, Kayaking, Citizen Science, Photography Seminars
Activity Level
Variable
Take an 11-day trip from Ushuaia, Argentina to Punta Arenas, Chile aboard Ocean Nova. Cross the Drake Passage, explore Antarctica by Zodiac, and visit the South Shetland Islands and King George Island. Observe penguins, seals, and whales, and learn from onboard experts during the journey.
Cruise Details
0
Black Turtle cove with mangroves
from $5,500
Savings
EXPLORE

Northern Islands

5 Day Itinerary aboard Alya
  • Swim and snorkel at Darwin Bay
  • Discover Genovesa Island's birdlife
  • Hike to Dragon Hill
Starts / Ends
Baltra / Charles Darwin Center
Activities
Stand Up Paddle Boarding
Activity Level
Variable
Sail to one of the most unique archipelagos in the world on this 5-day Galapagos Islands cruise aboard the Alya catamaran. The Galapagos Islands are teeming with sea life including blue-footed boobies, giant tortoises, land and marine iguanas, sea lions, and penguins.
Cruise Details
0
from $3,884
EXPLORE

Manu Explorer

8 Day Itinerary
  • See giant otters in oxbow lakes
  • Visit Macaw Clay Lick Project
  • Fall asleep to the forest sounds
  • Enjoy the changing scenery
Activity Level
Easy Active
Explore the Manu Cloud Forest wildlife safari through the breathtaking ecosystems of southeastern Peru. This 8-day journey takes you from the lofty Andean highlands and rugged puna grasslands into lush cloud forests alive with colorful birdlife, exotic flora, and diverse wildlife.
Tour Details
0
Trek the Route of the Parks of Patagonia
from $7,150
EXPLORE

Rincon Bonito: Patagonia's Hidden North

10 Day Itinerary
  • Rafting adventure on Petrohue River
  • Cochamo Valley Exploration
  • Paddling in Reloncaví Fjord
  • Trek the North Patagonian Andes
Starts / Ends
Puerto Montt / Puerto Varas
Activities
Village Visits, Hiking, Whitewater Rafting
Activity Level
Moderate
On the 10-day Rincon Bonito: Patagonia's Hidden North tour, explore Puerto Varas and the Chilean Patagonia Lake District. Highlights include a walking tour along Lake Llanquihue, rafting on the Petrohue River, a visit to Cochamo Valley, and a paddling adventure in the Reloncavi Fjord. Conclude the trip with a trek through the North Patagonian Andes.
Tour Details
0
Don\'t get too close
from $4,985
EXPLORE

Guyana Rainforest

6 Day Itinerary
  • Tour Georgetown’s historic markets
  • Paddle the Burro Burro River
  • Hike Surama Mountain trails
  • Visit majestic Kaieteur Falls
Activities
Wilderness Lodge Exploration, Cooking Classes
Activity Level
Easy Active
This 6-day adventure blends Guyanese culture with rainforest wilderness. Explore Georgetown's markets and colonial sights, then fly inland to Surama, a Macushi village. Climb Surama Mountain, sleep in a riverside hammock camp, and paddle the Burro Burro River for wildlife before a flight to Kaieteur, the world's tallest single-drop waterfall.
Tour Details
0
Enjoying the landscape of Lencois Maranhenses National Park
from $2,218
EXPLORE

Lençóis Maranhenses Trekking

6 Day Itinerary
  • Trek through dunes & lagoons
  • Swim in clear freshwater pools
  • Explore the town of Baixa Grande
  • Walk the charming streets of Atins
Activities
Camping
Activity Level
Moderate
Lencois Maranhenses Trekking is a Brazil tour itinerary offered through Adventure Life. Review the day-by-day highlights and what's included, or contact a trip planner to customize the itinerary to your travel dates and interests.
Tour Details
0
The Amazon River
from $12,880
EXPLORE

Luxury Amazon Expeditions Cruise - High Water

Roundtrip Iquitos - 8 Day Itinerary aboard Aqua Nera
  • Discover Iquitos cuisine
  • Spot Yanayacu Yacapana wildlife
  • Learn about Amazon fierce piranhas
  • Visit Clavero Lake villagers
Starts / Ends
Iquitos / Iquitos
Activities
Local Market Visits, Rainforest Exploration
Activity Level
Variable
Embark on an 8-day Amazon River cruise on the Aqua Nera, starting with a warm welcome and local cuisine in Iquitos. Explore rivers, wildlife, artisan markets, and conservation efforts, concluding your journey with a visit to the Manatee Rescue Center.
Cruise Details
0
A pair of friendly sea lions
from $9,945
Savings
EXPLORE

Island Circumnavigation

8 Day Itinerary aboard Galapagos Horizon
  • Discover Sullivan Bay's beauty
  • Observe mola-mola sunfish
  • Swim & snorel across Isabela Island
  • Visit South Plaza Islands
Starts / Ends
Baltra / San Cristobal Airport
Activity Level
Variable
This 8-day cruise offers incredible snorkeling, hiking, and kayaking adventures all around the Galapagos archipelago in style. Gourmet cuisine, the best guides, and spacious & stylish cabins guarantee a top-notch luxury cruising experience second to none.
Cruise Details
0
Uakari Floating Lodge
from $4,224
EXPLORE

Rio de Janeiro and Uakari Amazon Lodge

9 Day Itinerary
  • Enjoy views of Rio de Janeiro
  • Visit Christ the Redeemer
  • Learn about local flora and fauna
  • Canoe through flooded forests
Starts / Ends
Rio de Janeiro / Uakari Floating Lodge
Activities
Snorkeling, Urban Exploration
Activity Level
Relaxed
Rio de Janeiro and Uakari Amazon Lodge is a Brazil tour itinerary offered through Adventure Life. Review the day-by-day highlights and what's included, or contact a trip planner to customize the itinerary to your travel dates and interests.
Tour Details
0
361-372 of 550 Results

Relax. We've got this.

Talk with an expert trip planner 800.344.6118

Plan My Trip
Kevin Moore employee headshot
Kevin M.
Peruvian weavers
South America

Chat South America with a specialist

Our team is waiting and ready to talk with you about your next adventure. So go ahead and book an appointment with one of our specialized trip planners.

Let's Chat
800.344.6118

Where is your next adventure?

Contact Chat Call

Why Travel With Us?

Expert Guidance

With deep destination expertise in complex travel, we advise on how to maximize your time, avoid common pitfalls, and get the most out of every part of your trip.

Rewards That Go Further

Secure your 5% Past Traveler Rewards across a wide range of ships and destinations - not a single brand and not just cruises.

Unbiased Cruise Expertise

We're not tied to any one cruise line, so you receive honest guidance on the best ship and itinerary for you—not a sales pitch.

As Featured In

How it Works

Connect

No cost, no commitment. Talk with our experts about your dream trip.

Plan

Share your travel style—we match you with the right itinerary or create one just for you.

Book

Lock in knowing every detail is handled and you’re fully supported.

Travel

Enjoy a seamless journey—and unlock 5% off your next adventure.