Top South America Trips & Tours in October 2025

Begin your holiday Argentina hiking expedition by flying to Patagonia's El Calafate and then driving El Chalten, where you'll hike among glaciers and towering granite spires in the world-famous Fitz Roy Range. Discover Bariloche, the principal city of the Argentine Lakes District and a great base camp for enjoying various outdoor activities.

On this 10-day Patagonia cruise from Puerto Natales to Ushuaia aboard National Geographic Explorer, explore Chilean Patagonia’s fjords, glaciers, and vistas. Navigate coastlines by Zodiac and kayak, glide into fjords, and hike to spot wildlife. Discover the rare beauty of Karukinka Natural Park and Isla de los Estados (Staten Island).

Board the expeditionary river boat Tucano for a 5-day exploration of Brazil's Amazon rainforest along the Rio Negro. You will have daily opportunities to venture deep into the heart of the jungle as you tour the flooded forest of Igapo, visit indigenous communities and partake in their customs & traditions, and watch out for the incredible biodiversity.

Hike & Trek the best of Patagonia in Chile's Torres del Paine National Park on this abbreviated W-Trek adventure tour. Spend five days hiking in the backcountry exploring one of the world's most spectacular parks and spotting enormous glaciers, turquoise lakes, and verdant temperate rainforests. One of the world's premier hiking trips!

Venture into the Atacama Desert! Three to five night extensions include flexible itineraries that explore this unique region, including a visit to the Valley of the Moon, and the El Tatio geysers. Evenings are spent at the renowned Terrantai Lodge in San Pedro de Atacama.

Explore the wilds of Patagonia on this short but challenging hiking itinerary. Rewarded with panoramic vistas as your reach your destination each day, this itinerary designed for the active traveler.

The Galapagos are some of the world’s most famous and beguiling islands. The Infinity offers you the perfect opportunity to discover and enjoy this natural wonder next to your own group of up to 20 guests! Sailing across San Cristobal, Santa Fe, South Plaza, Isabela, Fernandina, and more.

From Iquitos, Peru, embark on the Zafiro for an eight-day tour highlighting the magnificent Amazon River's wonders. Navigate deep into Pacaya Samiria Reserve on an excursion to spot Amazonian marvels such as the pink river dolphin, many bird species, and all the animals that make this rainforest home.

This Galapagos cruise aboard the Tip Top IV takes you beyond the highlights of the Western Islands with 8 days of exciting activity! Enjoy the company of friendly sea lions while snorkeling and make friends with the gentle giant tortoises in Isabela and Santa Cruz.

Torres del Paine National Park offers a combination of unique wildlife and spectacular scenery in one of the most isolated regions of South America. Travel through Punta Arenas, Chile, or El Calafate, Argentina to arrive at EcoCamp. After full days of exploring the park return and rest in comfort in the new Suite Domes!

Take in the sights, sounds, food, and culture as you explore Santiago, Buenos Aires, and Rio de Janeiro. This 10 day itinerary includes free days and optional activities so you can set the pace of your South American vacation!

This 4-day Amazon cruise of Iquitos & Nauta aboard Amatista gives you an insider's view of life in Peru's rainforest, including piranha fishing, wildlife spotting, visit local villages, and opportunities to learn about wildlife preservation!

Adventure Life's guides and partners has identified the poorest families in the Cachiccata community. The elements can cause damage to homes over time, and many families do not have the extra means to make renovations to their homes. During this 4 day/3 night trip, participants, side-by-side with the family members, will work on cleaning, repairing, and restoring their homes. We stay in the community campground each night to immerse ourselves in the village life. The trip ends with traditional Inca ceremony and offering as a time to reflect over the previous days' experiences.

Embark on a 19-day cruise from Santiago to Ushuaia aboard the Seabourn Pursuit, exploring Chile's stunning coastline, Patagonia's fjords, and the pristine wilderness of Antarctica. Highlights include volcanic landscapes, penguin colonies, and majestic glaciers.

Take the opportunity to meet Argentina’s capital city, Buenos Aires! Often referred to as one of South America’s (and maybe the world’s) most exciting cities, Buenos Aires offers fabulous food, world famous wine, the Tango, amazing art, interesting neighborhoods. The city is interesting by day, and captivating by night.

Visit a traditional Estancia founded at the end of the 19th century just outside Torres del Paine National Park. Meet your local Baqueano (Patagonian cowboy) guide, who introduces you to the fine selection of Patagonian horses. Cross the Baguales River, famous for fly fishing due to its calm waters and lively trout.

Experience a 2 day/1 night whitewater rafting trip on the Urubamba River, the sacred river of the Incas. Raft through Class II-IV rapids on this trip that includes one overnight of camping and great food after your day's adrenaline-filled adventure on this great river.