Top South America Trips & Tours in September 2026

Discover three natural wonders of the world in one amazing trip: the Galapagos Islands, the Amazon Rainforest, and the Andes Mountains of Ecuador. Starting in Quito, fly to Sacha Lodge, deep in the Amazon, followed by the indigenous markets of Otavalo, staying at historic Hacienda Pinsaqui, culminating in the Wildlife Odyssey on an 8-day Galapagos cruise.

Experience the urban and rural environments of Bolivia on this combination tour! Take a city tour of La Paz, enjoy front row seats during the parade of dancers, tour a silver mine, and explore Lake Titicaca. These are just a few examples of what this adventure has in store for you!

During your visit to Rio de Janerio, visit the mountaintops of Corcovado and Sugarloaf, two of Rio's iconic peaks, and stroll the beaches of Ipanema and Copacabana. Fly to Manaus, the entrance of the Brazilian Amazon, and embark the Amazon Clipper for a 4-day cruise along the wildlife rich waters of the Rio Negro, one of the Amazon River's largest tributaries.

Explore the Amazon on this 5-day tour from the comfort of the community-run Uakari Floating Lodge. Located in the Mamirauá Sustainable Developments Reserve, this floating lodge offers a full-service experience. Spend your time hiking or canoeing through the forest learning about the local habitat and looking out for unique animals with your guide.

Explore the pristine lakes, rivers, and volcanoes that make up the Chilean Lake District on our 5 day tour. Nature hikes, wildlife viewing, kayaking, and fly fishing are activities that will ensure you experience all aspects of the Chilean Lake District!

Experience the Amazon on a 5-day cruise aboard Delfin III. Explore the Marañón, Yanallpa, Dorado, Pacaya, Magdalena, and Yarapa Rivers. Visit local communities, see pink dolphins, try piranha fishing, and witness the Amazon’s biodiversity. End in Iquitos with visits to a bee project and the Amazon Research Center.

Sail to one of the most unique archipelagos in the world on this 5-day Galapagos Islands cruise aboard the Alya catamaran. The Galapagos Islands are teeming with sea life including blue-footed boobies, giant tortoises, land and marine iguanas, sea lions, and penguins.

Experience Manu National Park, the most biologically diverse place on the planet, like virtually no one else can: camp inside the park at the Manu Wildlife Tent Camp. Delight in the sights and sounds of this 1.8 million-hectare jungle paradise.

Explore the Atacama Desert on a 7-day trekking tour through Chile’s most iconic landscapes. Hike Valle de la Luna, Rainbow Valley, and Guatin Valley. Visit ancient petroglyphs, the village of Rio Grande, the Tatio Geysers, and the Atacama Salt Flat. See flamingos at the turquoise Miscanti and Miñiques Lagoons before returning to Calama.

This 6-day tour of Bolivia's Amazon takes you to Madidi National Park, where you'll stay 3 nights in Madidi Jungle Ecolodge - Owned and operated by an indigenous community in Bolivia. Here, learn to see the jungle through the eyes of the local Quechua Indians as you explore and look for wildlife and learn about traditional farming & cuisine.

Enjoy 15 days of relaxing and fun aboard Samba yacht! Visit Santa Cruz, Floreana, Española, San Cristobal, Santa Fe, Santiago, Bartholomew, Rabida and North Seymour. Discover the magnificent wildlife and the incredible landscapes on Galapagos Islands .