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Minneapolis - St.Paul Mississippi River Cruises

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Minneapolis is a beautiful city that many of our northern Mississippi River cruises visit. Other major cities you will likely visit on your cruise include St. Louis, Memphis, Baton Rouge, and New Orleans. You will see many gorgeous small towns along the way and visit the highlights of many of the cities mentioned above and more. Learn about the Lewis and Clark expedition, the immigration that built this country, and the intricate lock system of the Mississippi River. Contact our travel specialists to start planning your ideal river cruise today!
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Best Minnesota Cruises |  Minneapolis - St. Paul River Cruises for 2027-2028

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Mississippi River Cruise Deals

Top Deals for Mississippi River Cruises to Minneapolis

Trip Name From Days Summary
Upper Mississippi River $5,635 9 Explore the Upper Mississippi River on this 9-day cruise from St. Louis to Minneapolis aboard the American Melody. Begin in St. Louis, Missouri, and travel through Alton, Hannibal, Muscatine, Dubuque, Winona, and Red Wing. Visit Mark Twain's boyhood home, explore historic towns, and marvel at the diverse landscapes.
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Upper Mississippi River $5,635 9 Explore the segment of the Mississippi River on this 9-day cruise from St. Louis to Minneapolis American Symphony. Begin in St. Louis, Missouri, and through Alton, Hannibal, Muscatine, Dubuque, Winona, and Red Wing. Visit Mark Twain's boyhood home, explore historic towns, and marvel at the diverse landscapes.
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Complete Mississippi River $15,890 23 Discover the Mighty Mississippi on a 23-day cruise covering 10 states aboard American Melody. Immerse in history, culture, and cuisine from New Orleans to Minneapolis, exploring charming ports along the way.
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Grand Heartland Cruise $12,620 16 Cruise the Mississippi River on a 16-day voyage aboard American Serenade. Visit La Crosse, Dubuque, Davenport, Hannibal, St. Louis, Memphis, Tunica, Vicksburg, Natchez, and Baton Rouge while exploring museums, riverfronts, historic landmarks, Civil War sites, and music destinations. Enjoy scenic cruising through the Upper and Lower Mississippi.
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All Five Great Lakes $7,499 11 Embark on an 11-day Great Lakes cruise from Chicago to Toronto aboard Victory I, exploring cities, islands, and historical sites. Enjoy scenic sailings and unique excursions.
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Great Lakes and St. Lawrence Seaway $8,299 13 Sail from Chicago to Montreal on a 13-day cruise aboard Victory I, exploring iconic cities, engineering marvels, and natural wonders. Scenic lake crossings offer time to unwind between dynamic destinations.
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All Five Great Lakes Reverse $6,799 11 Embark on an 11-day All Five Great Lakes cruise aboard Victory II and explore cultural hubs like Cleveland and Detroit, visit Niagara Falls, and relax on car-free Mackinac Island. Enjoy scenic days on Lake Ontario, Erie, Huron, Michigan, and Superior.
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Great Lakes and Thunder Bay $9,899 16 Sail from Chicago round-trip on a 16-day Great Lakes and Thunder Bay cruise aboard Victory II and explore scenic ports across the Great Lakes. Cruise through Lake Michigan and Lake Superior on a journey full of natural and historic highlights.
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Five Great Lakes and St. Lawrence Seaway $9,899 15 Explore the Great Lakes on a 15-day cruise from Quebec City to Chicago aboard Victory II. Visit Montreal, Niagara Falls, Cleveland, Detroit, Mackinac Island, and Milwaukee. Sail across Lakes Ontario, Erie, Huron, Superior, and Michigan. Experience iconic cities, rich history, scenic cruising, and cultural landmarks.
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Five Great Lakes and St. Lawrence Seaway $9,899 15 Sail from Chicago to Quebec on a 15-day cruise through the Great Lakes and St. Lawrence Seaway aboard Victory II. Visit iconic destinations like Mackinac Island, Niagara Falls, and Montreal. Explore vibrant cities, historic sites, and scenic waterways.
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