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Get the best deals on Mississippi river cruises and vacations with our exclusive travel discounts and deals. Everything is taken care of for you, from exceptional service on the ship to our expertly curated port excursions. Finding you the best deal on the best river cruise is what we do at Adventure Life. We've partnered with the top Mississippi river cruise companies, so we can negotiate the best deals with ship owners and pass the savings on to you. The key to choosing the right cruise is booking early. You'll have more alternatives and deals if you book early. If you wait until the last few months before your trip, you might get a discount, but the most popular ships might be full, leaving you with less-than-ideal options. Take advantage of our great deals on Mississippi river cruises and start exploring today!
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    • Mississippi River
$2,499
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Memphis to Louisville

9 Day Itinerary aboard American Duchess
  • Taste authentic local bourbon
  • Enjoy small-town hospitality
  • Listen to the music of Memphis
  • Explore artsy Louisville
Starts/ Ends in:
Memphis / Louisville
Activities:
River Cruises, Village Visits
Activity Level:
Relaxed
Board the American Duchess and join this delightful 9-day journey from Memphis, Tennessee to Louisville, Kentucky. Cruise the Mississippi and Ohio rivers and explore the cultural highlights of this region, from the musical traditions of Memphis and Owensboro to the artistic communities of Henderson …
Cruise Details
0
Explore the rivers of America
$2,799
Save 50%
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St. Louis to Minneapolis

9 Day Itinerary aboard American Duchess
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts/ Ends in:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Explore the land and river that inspired legendary American author Samuel Clemens, better known by his pen name, Mark Twain. Cruise northward from St. Louis, Missouri along the mighty Mississippi River, toward the city of Minneapolis. Along the way, explore port towns such as Hannibal, Missouri, …
Cruise Details
0
St. Louis' iconic arch at night
$2,499
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St. Louis to Minneapolis

9 Day Itinerary aboard American Queen
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts/ Ends in:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Explore the land and river that inspired legendary American author Samuel Clemens, better known by his pen name, Mark Twain. Cruise northward from St. Louis, Missouri along the mighty Mississippi River, toward the city of Minneapolis. Along the way, explore port towns such as Hannibal, Missouri, …
Cruise Details
0
$2,499
Save 50%
EXPLORE

Minneapolis to St. Louis

9 Day Itinerary aboard American Queen
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts/ Ends in:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Discover the region and river that inspired famed American novelist Samuel Clemens, better known as Mark Twain. On this 9-day cruise onboard American Queen, sail north from St. Louis, Missouri, along the magnificent Mississippi River toward the city of Minneapolis. Along the way, visit port towns …
Cruise Details
0
Explore beautiful Nashville
$1,999
Save 50%
EXPLORE

Nashville to Memphis

9 Day Itinerary aboard American Queen
  • Explore Nashville, Tennessee
  • Learn Civil War history
  • Visit the National Quilt Museum
  • Enjoy the music and food of Memphis
Starts/ Ends in:
Nashville / Memphis
Activities:
Archaeological Site Visits, River Cruises
Activity Level:
Relaxed
Immerse yourself in the history, music, and culture of this distinctive region on this enchanting 9-day journey on the Cumberland and Mississippi rivers. Set sail from Nashville, considered by many to be the capital of country music. Experience laid-back, small-town charm in Dover, Tennessee, and …
Cruise Details
0
Visit historic St. Louis
$2,399
Save 50%
EXPLORE

St. Louis to Minneapolis

9 Day Itinerary aboard American Countess
  • Explore the culture of St. Louis
  • See Mark Twains hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts/ Ends in:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Relaxed
Explore the country and river that inspired Mark Twain, the pen name of the famed American novelist Samuel Clemens. From St. Louis, Missouri, cruise north along the magnificent Mississippi River towards Minneapolis. Explore port towns such as Hannibal, Missouri, the birthplace of Mark Twain, and …
Cruise Details
0
New Orleans paddlewheel steamer in New Orleans, Lousiana
$1,999
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New Orleans to Memphis

9 Day Itinerary aboard American Queen
  • Explore vibrant New Orleans
  • Experience the music of Memphis
  • Learn the history of Vicksburg
  • Explore Nottoway Plantation
Starts/ Ends in:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
Explore beautiful Nashville
$2,399
Save 50%
EXPLORE

Nashville to St. Louis

9 Day Itinerary aboard American Countess
  • Explore Nashville, Tennessee
  • Visit the National Quilt Museum
  • Experience small-town charm
  • Stop at the Popeye Character Trail
  • Enjoy the museums of St. Louis
Starts/ Ends in:
Nashville / Alton
Activities:
River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Set sail on a 9-day river cruise along the Cumberland and Mississippi rivers to learn about the region's history, music, and culture. Set out from Nashville, which is widely regarded as the country music capital of the world. The small hamlet of Dover, Tennessee, is a fascinating place to visit …
Cruise Details
0
Enjoy vibrant nightlife and live music
$2,299
Save 50%
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Memphis to St. Louis

(or reverse) - 9 Day Itinerary aboard American Duchess
  • Explore Memphis
  • Discover New Madrid
  • Experience Paducah's history
  • Visit Cape Girardeau
Starts/ Ends in:
Memphis / St. Louis
Activities:
River Cruises, Small Ship Cruises, Urban Exploration
Activity Level:
Relaxed
From Memphis to St. Louis, the Lower Mississippi River is loaded with stories to tell. From the legacies that line the Mississippi to the imaginative corners of Ohio, this 9-day riverboat tour promises a variety of enlightening encounters and unforgettable memories. Explore the seismic wonders of …
Cruise Details
0
Legendary Sun Studios in Memphis, TN
$1,999
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Louisville to Memphis

9 Day Itinerary aboard American Duchess
  • Experience the music of Memphis
  • Enjoy the music of Owensboro
  • Taste locally produced bourbon
  • Relax into a laid-back lifestyle
Starts/ Ends in:
Louisville / Memphis
Activities:
Adventure Options, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Cruise the Mississippi and Ohio rivers aboard the American Duchess on this 9-day cruise with a particular focus on the musical history and culture of this unique region. Board your ship in Louisville, Kentucky, where you can also get a taste of famous locally-produced Kentucky bourbon. Visit a …
Cruise Details
0
Visit historic St. Louis
$2,599
Save 50%
EXPLORE

Memphis to St. Louis

9 Day Itinerary aboard American Queen
  • Listen to the music of Memphis
  • Explore wonders of New Madrid
  • Admire historic handicrafts
  • Explore the culture of St. Louis
Starts/ Ends in:
Memphis / St. Louis
Activities:
River Cruises, Village Visits
Activity Level:
Relaxed
Board the American Queen and join this delightful 9-day journey From the legacies that line the Mississippi River to the corners of creative genius along Ohio, your riverboat journey promises a wealth of eye-opening experiences and memories. Explore the seismic wonders of New Madrid and the iconic …
Cruise Details
0
$2,599
Save 50%
EXPLORE

Louisville to St. Louis (Alton)

9 Day Itinerary aboard American Queen
  • Taste famous Kentucky bourbon
  • Explore vibrant St. Louis
  • Enjoy the music of Owensboro
  • Admire historic handicrafts
Starts/ Ends in:
Louisville / St. Louis
Activities:
River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Board the American Queen riverboat and cruise through the heart of the American Midwest on this 9-day journey from Louisville, Kentucky to St. Louis, Missouri on the Ohio and Mississippi Rivers. Experience the laid-back, small-town hospitality of Kentucky ports such as Owensboro, where you'll …
Cruise Details
0
Visit historic St. Louis
$2,599
Save 50%
EXPLORE

St. Louis to Louisville

9 Day Itinerary aboard American Queen
  • Taste famous Kentucky bourbon
  • Explore vibrant St. Louis
  • Enjoy the music of Owensboro
  • Visit National Quilt Museum
Starts/ Ends in:
Louisville / St. Louis
Activities:
River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Board the American Queen riverboat and cruise through the heart of the American Midwest on this 9-day journey from St. Louis to Louisville on the Ohio and Mississippi Rivers. Experience the laid-back, small-town hospitality of Kentucky ports such as Owensboro, where classic folk music and …
Cruise Details
0
Explore beautiful Nashville
$2,799
Save 50%
EXPLORE

Nashville to St. Louis

8 Day Itinerary aboard American Duchess
  • Explore Nashville, Tennessee
  • Visit the National Quilt Museum
  • Experience small-town charm
  • Stop at the Popeye Character Trail
  • Enjoy the museums of St. Louis
Starts/ Ends in:
Nashville / Alton
Activities:
River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Immerse yourself in the history, music, and culture of this distinctive region on this enchanting 8-day journey on the Cumberland and Mississippi rivers. Set off from Nashville, considered by many to be the capital of country music. Experience laid-back, small-town charm in Dover, Tennessee, and …
Cruise Details
0
$2,299
Save 50%
EXPLORE

Louisville to St. Louis

9 Day Itinerary aboard American Countess
  • Taste famous Kentucky bourbon
  • Enjoy the music of Owensboro
  • Admire historic handicrafts
  • Explore vibrant St. Louis
Starts/ Ends in:
Louisville / St. Louis
Activities:
River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Board the American Countess riverboat and cruise through the heart of the American Midwest on this 9-day journey from Louisville, Kentucky to St. Louis, Missouri on the Ohio and Mississippi Rivers. Experience the laid-back, small-town hospitality of Kentucky ports such as Owensboro, where …
Cruise Details
0
Explore beautiful Nashville
$2,599
Savings
EXPLORE

St. Louis to Nashville

9 Day Itinerary aboard American Queen
  • Explore Nashville, Tennessee
  • Visit the National Quilt Museum
  • Experience small-town charm
  • Stop at the Popeye Character Trail
  • Enjoy the museums of St. Louis
Starts/ Ends in:
Nashville / Alton
Activities:
River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Immerse yourself in the history, music, and culture of this distinctive region on this enchanting 9-day journey on the Cumberland and Mississippi rivers. Set off from St. Louis, Missouri, the "Gateway to the West" and home to a colorful history and a vibrant arts scene.Learn about the …
Cruise Details
0
Visit historic Chicago, Illinois
$2,399
Save 50%
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Illinois River: Chicago to St. Louis

Chicago to St. Louis - 9 Day Itinerary aboard American Countess
  • Explore the city of Chicago
  • Discover the hometown of Mark Twain
  • Find history in Peoria
  • Enjoy the natural beauty of Alton
Starts/ Ends in:
Chicago / St. Louis
Activities:
River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Board American Countess on this 9-day cruise exploring highlights of the Illinois River. Explore the legacy of the American midwest on this river cruise through the historic heartland from Chicago to St. Louis. This journey takes you to a variety of beautiful American port cities in a luxury cruise …
Cruise Details
0
1-17 of 17 Results

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