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Missouri

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Select one of the below 34 best Missouri trips for 2022 and 2023. Your local English speaking guide will lead your small group or personalized private tour on an extraordinary adventure exploring St. Louis, Cape Girardeau, Hannibal, and New Madrid. Our amazing Missouri trips for 2022 feature river cruises, cruises, cultural, village visits, and classic, and start from $1,999 for trips of 8 to 16 days. Most of the trips and itineraries below can be customized to meet your precise needs. Just contact one of Adventure Life's Missouri trip planning experts to start planning your next seamless trip.
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Visit historic St. Louis
$2,699
Savings
EXPLORE

Memphis to St. Louis

9 Day Itinerary aboard American Queen
  • Listen to the music of Memphis
  • Explore wonders of New Madrid
  • Admire historic handicrafts
  • Explore the culture of St. Louis
Starts/ Ends in:
Memphis / St. Louis
Activities:
River Cruises, Village Visits
Activity Level:
Relaxed
Board the American Queen and join this delightful 9-day journey From the legacies that line the Mississippi River to the corners of creative genius along Ohio, your riverboat journey promises a wealth of eye-opening experiences and memories. Explore the seismic wonders of New Madrid and the iconic …
Cruise Details
0
Explore the rivers of America
$2,799
Savings
EXPLORE

St. Louis to Minneapolis

9 Day Itinerary aboard American Duchess
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts/ Ends in:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Explore the land and river that inspired legendary American author Samuel Clemens, better known by his pen name, Mark Twain. Cruise northward from St. Louis, Missouri along the mighty Mississippi River, toward the city of Minneapolis. Along the way, explore port towns such as Hannibal, Missouri, …
Cruise Details
0
View the iconic arch when you visit St. Louis, gateway to the west
$10,499
EXPLORE

America’s Great River

St. Paul to New Orleans - 15 Day Itinerary aboard Viking Mississippi
  • Explore St. Louis' arts scene
  • Enjoy American music styles
  • Learn Civil War history
  • Experience New Orleans' culture
  • Visit the Quad Cities
Starts/ Ends in:
St. Paul / New Orleans
Activities:
Archaeological Sites, River Cruise, Village Visit
Activity Level:
Relaxed
Discover the history, natural beauty, and distinctive regional cultures of America's great river, the mighty Mississippi, on this 15-day cruise aboard Viking Mississippi. Set sail from St. Paul, Minnesota, and venture south toward New Orleans, Louisiana. Along the way, visit small towns and …
Cruise Details
0
View monuments from the Civil War in Mississippi
$5,499
EXPLORE

Minneapolis to New Orleans

16 Day Itinerary aboard American Duchess
  • Enjoy musical history in Memphis
  • Explore the arts in Minneapolis, MN
  • Discover St. Louis, Missouri
  • Admire the diversity of New Orleans
  • Learn about Civil War history
Starts/ Ends in:
Minneapolis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Watch landscapes, cultures and even language transform as you cruise along the Mississippi river from Minneapolis to New Orleans aboard the American Duchess. Board this 16-day cruise to sail nearly the full length of the mighty Mississippi. Along the way, visit historic port cities and laid-back …
Cruise Details
0
$2,299
EXPLORE

Louisville to St. Louis

9 Day Itinerary aboard American Countess
  • Taste famous Kentucky bourbon
  • Enjoy the music of Owensboro
  • Admire historic handicrafts
  • Explore vibrant St. Louis
Starts/ Ends in:
Louisville / St. Louis
Activities:
River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Board the American Countess riverboat and cruise through the heart of the American Midwest on this 9-day journey from Louisville, Kentucky to St. Louis, Missouri on the Ohio and Mississippi Rivers. Experience the laid-back, small-town hospitality of Kentucky ports such as Owensboro, where …
Cruise Details
0
Enjoy vibrant nightlife and live music
$2,299
EXPLORE

Memphis to St. Louis

(or reverse) - 9 Day Itinerary aboard American Duchess
  • Explore Memphis
  • Discover New Madrid
  • Experience Paducah's history
  • Visit Cape Girardeau
Starts/ Ends in:
Memphis / St. Louis
Activities:
River Cruises, Small Ship Cruises, Urban Exploration
Activity Level:
Relaxed
From Memphis to St. Louis, the Lower Mississippi River is loaded with stories to tell. From the legacies that line the Mississippi to the imaginative corners of Ohio, this 9-day riverboat tour promises a variety of enlightening encounters and unforgettable memories. Explore the seismic wonders of …
Cruise Details
0
Visit historic St. Louis
$2,399
EXPLORE

St. Louis to Minneapolis

9 Day Itinerary aboard American Countess
  • Explore the culture of St. Louis
  • See Mark Twains hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts/ Ends in:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Relaxed
Explore the country and river that inspired Mark Twain, the pen name of the famed American novelist Samuel Clemens. From St. Louis, Missouri, cruise north along the magnificent Mississippi River towards Minneapolis. Explore port towns such as Hannibal, Missouri, the birthplace of Mark Twain, and …
Cruise Details
0
Explore historic New Orleans
$5,099
EXPLORE

Minneapolis to New Orleans

16 Day Itinerary aboard American Queen
  • Enjoy musical history in Memphis
  • Admire the diversity of New Orleans
  • Discover St. Louis, Missouri
  • Explore the arts in Minneapolis, MN
  • Learn about Civil War history
Starts/ Ends in:
Minneapolis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Watch landscapes, cultures and even language transform as you cruise along the Mississippi river from Minneapolis to New Orleans aboard the American Queen. Board this 16-day cruise to sail nearly the full length of the mighty Mississippi. Along the way, visit historic port cities and laid-back …
Cruise Details
0
Visit historic St. Louis
$2,899
EXPLORE

Minneapolis to St. Louis

9 Day Itinerary aboard American Duchess
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts/ Ends in:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Relaxed
Discover the region and river that inspired renowned American novelist Samuel Clemens, better known as Mark Twain. Sail north from Minneapolis on this 9-day voyage aboard American Countess along the gorgeous Mississippi River toward the city of St. Louis. Along the way, stop in port towns such as …
Cruise Details
0
Enjoy vibrant nightlife and live music
$2,799
EXPLORE

Nashville to Memphis

9 Day Itinerary aboard American Duchess
  • Explore Nashville, Tennessee
  • Experience small-town charm
  • Visit the National Quilt Museum
  • Enjoy the music and food of Memphis
Starts/ Ends in:
Nashville / Memphis
Activities:
River Cruises
Activity Level:
Relaxed
Immerse yourself in the history, music, and culture of this distinctive region on this enchanting 9-day journey on the Cumberland and Mississippi rivers. Set sail from Nashville, considered by many to be the capital of country music. Experience laid-back, small-town charm in Dover, Tennessee, and …
Cruise Details
0
$2,499
EXPLORE

Minneapolis to St. Louis

9 Day Itinerary aboard American Queen
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts/ Ends in:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Discover the region and river that inspired famed American novelist Samuel Clemens, better known as Mark Twain. On this 9-day cruise onboard American Queen, sail north from St. Louis, Missouri, along the magnificent Mississippi River toward the city of Minneapolis. Along the way, visit port towns …
Cruise Details
0
Explore beautiful Nashville
$2,799
EXPLORE

Nashville to St. Louis

8 Day Itinerary aboard American Duchess
  • Explore Nashville, Tennessee
  • Visit the National Quilt Museum
  • Experience small-town charm
  • Stop at the Popeye Character Trail
  • Enjoy the museums of St. Louis
Starts/ Ends in:
Nashville / Alton
Activities:
River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Immerse yourself in the history, music, and culture of this distinctive region on this enchanting 8-day journey on the Cumberland and Mississippi rivers. Set off from Nashville, considered by many to be the capital of country music. Experience laid-back, small-town charm in Dover, Tennessee, and …
Cruise Details
0
Explore beautiful Nashville
$1,999
Savings
EXPLORE

Nashville to Memphis

9 Day Itinerary aboard American Queen
  • Explore Nashville, Tennessee
  • Learn Civil War history
  • Visit the National Quilt Museum
  • Enjoy the music and food of Memphis
Starts/ Ends in:
Nashville / Memphis
Activities:
Archaeological Site Visits, River Cruises
Activity Level:
Relaxed
Immerse yourself in the history, music, and culture of this distinctive region on this enchanting 9-day journey on the Cumberland and Mississippi rivers. Set sail from Nashville, considered by many to be the capital of country music. Experience laid-back, small-town charm in Dover, Tennessee, and …
Cruise Details
0
Visit historic Chicago, Illinois
$2,399
EXPLORE

Illinois River: Chicago to St. Louis

Chicago to St. Louis - 9 Day Itinerary aboard American Countess
  • Explore the city of Chicago
  • Discover the hometown of Mark Twain
  • Find history in Peoria
  • Enjoy the natural beauty of Alton
Starts/ Ends in:
Chicago / St. Louis
Activities:
River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Board American Countess on this 9-day cruise exploring highlights of the Illinois River. Explore the legacy of the American midwest on this river cruise through the historic heartland from Chicago to St. Louis. This journey takes you to a variety of beautiful American port cities in a luxury cruise …
Cruise Details
0
Explore beautiful Nashville
$2,799
EXPLORE

Memphis to Nashville

9 Day Itinerary aboard American Duchess
  • Explore Nashville, Tennessee
  • Experience Dover's small-town charm
  • Visit the National Quilt Museum
  • Enjoy the music and food of Memphis
Starts/ Ends in:
Nashville / Memphis
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Relaxed
On this delightful 9-day adventure along the Cumberland and Mississippi rivers, immerse yourself in history, music, and culture. As you begin your adventure through the Home of the Blues, the earth blooms with a rainbow of greens. Stand on the deck and take in the splendor of the transformation …
Cruise Details
0
Explore beautiful Nashville
$2,699
EXPLORE

Memphis to Nashville

9 Day Itinerary aboard American Queen
  • Explore Nashville, Tennessee
  • Experience small-town charm
  • Visit the National Quilt Museum
  • Enjoy the music and food of Memphis
Starts/ Ends in:
Memphis / Clarksville
Activities:
River Cruises
Activity Level:
Relaxed
Discover the history, music, and culture of this distinct region on this 9-day adventure along the Cumberland and Mississippi rivers. As you begin your adventure in the Home of the Blues, the planet erupts in a profusion of greens. Observe the transformation's splendor while standing on the …
Cruise Details
0
Explore beautiful Nashville
$2,599
Savings
EXPLORE

St. Louis to Nashville

9 Day Itinerary aboard American Queen
  • Explore Nashville, Tennessee
  • Visit the National Quilt Museum
  • Experience small-town charm
  • Stop at the Popeye Character Trail
  • Enjoy the museums of St. Louis
Starts/ Ends in:
Nashville / Alton
Activities:
River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Immerse yourself in the history, music, and culture of this distinctive region on this enchanting 9-day journey on the Cumberland and Mississippi rivers. Set off from St. Louis, Missouri, the "Gateway to the West" and home to a colorful history and a vibrant arts scene.Learn about the …
Cruise Details
0
Explore beautiful Nashville
$2,799
EXPLORE

Nashville to St. Louis

9 Day Itinerary aboard American Duchess
  • Explore Nashville, Tennessee
  • Visit the National Quilt Museum
  • Experience small-town charm
  • Stop at the Popeye Character Trail
  • Enjoy the museums of St. Louis
Starts/ Ends in:
Nashville / Alton
Activities:
River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Spend time learning about North America's rich heritage through its music and arton this enchanting 9-day journey on the Cumberland and Mississippi rivers. Set off from Nashville, considered by many to be the capital of country music. Experience laid-back, small-town charm in Dover, Tennessee, …
Cruise Details
0
1-18 of 34 Results

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