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Top Mekong River Trips & Tours in October 2025

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Discover Mekong River in October 2025 on one of these 33 tours hand-selected by the travel experts at Adventure Life. Explore the best of during October 2025 as you enjoy Village Visits, Local Market Visits, Archaeological Site Visits, Biking, and Wildlife Viewing. Prices for trips in October 2025 range from $990 to $23,290 for a vacation of 5 to 16 days. Choose any of the below 33 itineraries in October 2025 and customize it when you contact one of Adventure Life's expert Mekong River trip planners.
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    • Mekong River
Phnom Penh Royal Palace complex
from $2,124
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard The Jahan
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jahan. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.
  • Observed locals along the river
  • See the floating market in Cai Be
  • Visit Phnom Penh cultural sites
  • Visit Tan Chau floating fish farm
Cruise Details
0
Sunset over the Mekong River
from $3,358
EXPLORE

Classic Mekong

Upstream - 8 Day Itinerary aboard RV Bassac Pandaw
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Fishing
Activity Level
Variable
Explore both Vietnam's and Cambodia's striking cultural contrast in this 8-day Upstream Classic Mekong Cruise from Saigon to Siem Reap aboard RV Bassac Pandaw. Travel from the vibrant French colonial port of Saigon through the vast delta so rich in human life and endeavor to the rich countryside of Cambodia.
  • Explore the floating markets
  • Explore riverside villages
  • See Phnom Penh's National Museum
Cruise Details
0
Everyday life in Vietnam
from $3,439
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Charms of the Mekong - Cruise Only

Ho Chi Minh - Siem Reap - 8 Day Itinerary aboard MS Amadara
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Embark on an 8-day river cruise aboard the MS Amadara, starting in Ho Chi Minh City, a vibrant blend of history and modernity. Cruise the Mekong River, exploring villages, pagodas, and markets and experiencing local traditions, including a monk’s blessing and artisan crafts.
  • Explore Cai Be’s vibrant workshops
  • Discover Sa Dec history
  • Visit Phnom Penh landmarks
  • Experience Oknhatey, silk weaving
Cruise Details
0
Boat floating along the Mekong River
EXPLORE

Experience the Mekong by Cruise

1 Day Itinerary
Starts / Ends
Mekong River / Mekong River
Activity Level
Relaxed
This one-day Vietnam tour extension includes a cruise along the Mekong River and visits to other scenic locations. Visit Ben Tre, My Long, a coconut workshop, a bee garden, a candy mill, and a farmer's house, and ride a rickshaw past coconut trees and vegetable farms.
  • Visit a candy mill
  • Visit a coconut workshop
  • Enjoy biking or ride on a rickshaw
Tour Details
0
Royal Palace and Silver Pagoda
from $1,956
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard Jayavarman
Starts / Ends
Phnom Penh / Ho Chi Minh City
Activity Level
Variable
Cruise downstream on the Mekong River in majestic style aboard the Jayavarman on this 4-day journey from Phnom Penh to Saigon. Learn about the culture and heritage with visits to rural villages, historic pagodas, and colorful markets
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit Tan Chau floating fish farm
Cruise Details
0
Traditional mat-making
from $2,124
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard The Jahan
Starts / Ends
Phnom Penh / My Tho
Activities
Biking
Activity Level
Variable
On this 4-day journey from Phnom Penh to Saigon, cruise downstream on the lower Mekong River in majestic style aboard the Jahan. See the stunning scenery and discover the culture and history of the various towns along the mighty Mekong.
  • Experience Binh Thanh Island
  • Explore My An Hung Village
  • Discover Tan Chau
  • Experience Cao Dai
Cruise Details
0
Phnom Penh Royal Palace complex
from $1,956
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard Jayavarman
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jayavarman. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.
  • Observed locals along the river
  • See the floating market in Cai Be
  • Visit Phnom Penh cultural sites
  • Visit Tan Chau floating fish farm
Cruise Details
0
The Vinh Trang Temple in My Tho, Vietnam
from $3,529
EXPLORE

From the Angkor Temples to the Mekong Delta

Siem Reap - Ho Chi Minh - 11 Day Itinerary aboard RV Indochine
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Experience an 11-day cruise on the RV Indochine from Siem Reap to Ho Chi Minh City, navigating over 2,700 miles of the Mekong River. Explore cultural landmarks like Angkor and Phnom Penh, all while enjoying colonial-inspired comfort aboard your vessel.
  • Visit the Banteay Srei temple
  • Explore the terrace of Elephants
  • Discover Kampong Chhnang
  • Tour Phnom Penh's National Museum
Cruise Details
0
Vietnam's bird sanctuary
from $10,290
NO SS
EXPLORE

Mekong Expedition - Ho Chi Minh to Siem Reap

High water - 8 Day Itinerary aboard Aqua Mekong
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Board the Aqua Mekong for an unforgettable 8-day cruise up the Mekong River from Saigon, Vietnam to Siem Reap, Cambodia, with stops in Phnom Penh and Tonle Sap Lake, among other highlights of the Indochina peninsula. Biking, hiking, cultural immersion, market visits, and cooking classes highlight the cruise.
  • Experience vibrant markets
  • Enjoy touring Cambodia's capital
  • Visit Long Son Pagoda
  • Explore Prek Toal Core Bird Reserve
Cruise Details
0
Sanctuary Spa
from $990
EXPLORE

Farm House Resort and Spa Extension

4 Day Itinerary
Starts / Ends
Phnom Penh / Kampong Chhnang
Activities
Spa Relaxation, Village Visits
Activity Level
Relaxed
This 4-day tour starts in Phnom Penh or Battambang. Drive about 1 hour and 30 minutes from Phnom Penh or 4 hours from Battambang. Upon arrival, settle into the Smiling Gecko Farmhouse. Relax and enjoy the natural surroundings and delicious meals provided throughout your stay.
  • Discover Kampong Chhnang
  • Relax at the Farmhouse Resort & Spa
  • Support local Cambodians
Tour Details
0
Kampong Chhnang
from $3,439
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Riches of the Mekong - Cruise Only

8 Day Itinerary aboard MS Amadara
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Wildlife Viewing, Land & Sea Exploration
Activity Level
Variable
Embark on an 8-day river cruise from Siem Reap to Ho Chi Minh aboard the MS Amadara, exploring rural villages, bustling markets, and historic sites. Experience Cambodia and Vietnam’s rich culture through artisan crafts, temple visits, and unique rides by oxcart, tuk-tuk, and trishaw.
  • Explore Angkor Ban village
  • Visit Oknhatey, Silk Island
  • Tour Phnom Penh highlights
  • Discover Oudong, royal capital
Cruise Details
0
The floating village of Tonle Sap, Cambodia
from $6,200
NO SS
EXPLORE

Mekong Explorer - Ho Chi Minh to Siem Reap (Extension)

5 Day Itinerary aboard Aqua Mekong
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
Board the Aqua Mekong in My Tho for a 5-day Mekong River cruise of Cambodia & Vietnam, including stops in Ho Chi Minh City, Phnom Penh, and Long Son Pagoda atop Sam Mountain. Travel back in time as you cruise upriver through the thriving Mekong Delta past floating villages, colonial vestiges, and gilded pagodas.
  • Enjoy a visit to a local's home
  • Walk through verdant plantations
  • Meet & interact with Buddhist Monks
Cruise Details
0
Floating Market in Cai Be
from $4,299
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard The Jahan
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Join this 8-day Mekong River cruise during the high water season from Siem Reap to Saigon. Get an inside look at the southern cultures of Vietnam and Cambodia as you travel across the mighty Mekong delta. Stop in charming port towns and immerse yourself in the city's culture and history.
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Tan Chau floating fish farm
  • Visit Phnom Penh cultural sites
Cruise Details
0
Flower farms in Sa Dec, Vietnam
from $3,788
EXPLORE

Mekong River - Upstream - High water

Saigon to Siem Reap - 8 Day Itinerary aboard Jayavarman
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Local Market Visits, Archaeological Site Visits
Activity Level
Variable
Embark on this 8-day high river expedition on the Jayavarman and experience the Mekong River as it flows from Saigon to Siem Reap. Explore the lower Mekong and discover the diverse cultures and historical significance of the towns along its course.
  • Explore rural villages
  • Discover skilled craftsmanship
  • Experience scenic views at Delta
  • Explore floating markets
  • Discover cultures of Mekong Delta
Cruise Details
0
Sunset over the Mekong River
from $3,788
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard Jayavarman
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Cooking Classes
Activity Level
Variable
Explore the Mekong on this 8-day high-water Mekong River cruise from Siem Reap to Saigon. Get an inside look at the southern cultures of Vietnam and Cambodia as you travel across the mighty Mekong Delta. Stop in charming port towns and immerse yourself in the city's culture and history.
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Tan Chau floating fish farm
  • Visit Phnom Penh cultural sites
Cruise Details
0
Local moving cattle through the fields
from $5,098
EXPLORE

From the Temples of Angkor to the Mekong Delta & Hanoi and Halong Bay

14 Day Itinerary aboard RV Indochine
Starts / Ends
Siem Reap / Hanoi
Activities
Urban Exploration
Activity Level
Variable
This 14-day Mekong River cruise through Cambodia and Vietnam aboard the RV Indochine travels from Siem Reap in Cambodia to Hanoi, Vietnam observing imposing monuments, examples of finest architecture, and extraordinary landscapes, like those of famous Angkor Wat. Also visit Chau Doc, Ho Chi Minh City, Kampong Tralach, Koh Chen, My Tho, Sa Dec, & Tonle Sap Lake.
  • Discover 3 historical cities
  • Cross through the Cho Gao canal
  • Visit 4 major temples in Angkor
  • Meet locals and learn their culture
Cruise Details
0
Beautiful architecture in Tonle Sap
from $4,650
NO SS
EXPLORE

Mekong Discovery - Phnom Penh to Siem Reap

High water - 4 Day Itinerary aboard Aqua Mekong
Activity Level
Variable
Experience the colorful culture of Vietnam and Cambodia as you embark on this 4-day Mekong River Discovery Cruise and experience a richly-rewarding adventure by heading upriver in Cambodia and exploring the Tonle Sap Lake.
  • Experience an indigenous tradition
  • Discover Koh Chen´s pottery
  • Explore the Moat Khla village
Cruise Details
0
Royal Palace and Silver Pagoda
from $1,919
EXPLORE

Phnom Penh and Siem Reap

Downstream - 4 Day Itinerary aboard RV Mekong Pandaw
Starts / Ends
Siem Reap / Phnom Penh
Activity Level
Variable
Discover Cambodia on this 4-day cruise aboard RV Mekong Pandaw. Combine the ancient Khmer martial art of Bokator in Silk Island with a visit to Vipassana Dhura Meditation Center in Cambodia's ancient capital, Oudongon, on this expedition across the Tonle and Mekong Rivers.
  • Sunset cruise on Mekong
  • Explore pottery at Peam Chi Korng
  • Watch silk weaving demonstrations
  • Meditation at Oudong temple
Cruise Details
0
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